Clinical Trials Directory

Trials / Terminated

TerminatedNCT02504619

Allogeneic SCT of CordIn™, in Patients With Hemoglobinopathies

Allogeneic Stem Cell Transplantation of CordIn™, Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells, in Patients With Hemoglobinopathies

Status
Terminated
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
1 (actual)
Sponsor
Gamida Cell ltd · Industry
Sex
All
Age
2 Years – 25 Years
Healthy volunteers
Not accepted

Summary

CordIn™ is a cryopreserved stem/progenitor cell-based product of purified CD133+ cells composed of ex vivo expanded allogeneic UCB cells. The overall study objectives are to evaluate the safety and efficacy of CordIn™.

Detailed description

CordIn™ is a cryopreserved stem/progenitor cell-based product of purified CD133+ cells composed of ex vivo expanded allogeneic UCB cells. The trial ends when the last patient completes their last visit. The overall study objectives are to evaluate the safety and efficacy of CordIn™: single ex-vivo expanded cord blood unit transplantation in patients with hemoglobinopathies (sickle cell disease or thalassemia major) following a preparative therapy.

Conditions

Interventions

TypeNameDescription
BIOLOGICALCordInCordIn™ is a cryopreserved stem/progenitor cell-based product of purified CD133+ cells composed of ex vivo expanded allogeneic UCB cells.

Timeline

Start date
2016-04-04
Primary completion
2016-08-01
Completion
2017-12-01
First posted
2015-07-22
Last updated
2019-06-26
Results posted
2019-06-26

Locations

3 sites across 2 countries: United States, France

Source: ClinicalTrials.gov record NCT02504619. Inclusion in this directory is not an endorsement.