| Not Yet Recruiting | Application of Multimodal MRI in Histological Grading and Prognostic Assessment of Rectal Cancer NCT07269912 | Sichuan Cancer Hospital and Research Institute | — |
| Active Not Recruiting | Optimization and Standardization of Single-Port Robotic Transanal Minimally Invasive Surgery for Rectal Tumor NCT07522294 | Jeng-Fu You | N/A |
| Enrolling By Invitation | The SMART Trial: Modified Single-Stapled Anastomosis in Laparoscopic or Robotic Low Anterior Resection for Rec NCT07376980 | Korea University Anam Hospital | N/A |
| Not Yet Recruiting | RATME Vs LATME in Middle and Low Rectal Cancer NCT06105203 | The First Hospital of Jilin University | N/A |
| Not Yet Recruiting | Endoscopic Submucosal Dissection vs. Transanal Endoscopic Surgery for Rectal Neoplasia NCT06902701 | Turkish Society of Colon and Rectal Surgery | — |
| Recruiting | Comprehensive Analysis of Gut Microbiota Signatures in Metastatic Colorectal Cancer NCT07154173 | Sixth Affiliated Hospital, Sun Yat-sen University | — |
| Completed | MRA Diameter as a Predictor for LLN Metastasis in Rectal Cancer. NCT07419516 | First Affiliated Hospital of Fujian Medical University | — |
| Completed | PeLear CCC: Proyecto Latino Contra Cancer Colorrectal NCT06426927 | University of North Carolina, Chapel Hill | N/A |
| Not Yet Recruiting | Effect of Pelvic Rehabilitation After Low Anterior Resection for Cancer Rectum. - A Randomised Controlled Tria NCT06524362 | GEM Hospital & Research Center | N/A |
| Unknown | Peritoneum and Anterior Rectus Sheath Suturing and Ileostomy NCT06344923 | Qilu Hospital of Shandong University | N/A |
| Not Yet Recruiting | Organ Preservation With Tislelizumab and Total Neoadjuvant Therapy in Patients With Low Rectal Cancer: RELIEVE NCT06390982 | Fudan University | Phase 2 |
| Recruiting | Selection of Surgical Technique in Rectal Cancer NCT06442215 | Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta | — |
| Recruiting | Study for Wait and Watch Suitable in Rectal Cancer NCT06252142 | Tata Memorial Centre | — |
| Not Yet Recruiting | No Stoma VS Ghost Stoma in Patients Undergoing Total Mesorectal Excision for Rectal Cancer NCT06225609 | fan li | N/A |
| Unknown | The Safety and Efficiency of Stent-based Diverting Technique Versus Ileostomy in Rectal Cancer Patients NCT06204497 | Sir Run Run Shaw Hospital | N/A |
| Recruiting | SGM-101 in Colorectal Brain Metastases. NCT04755920 | Leiden University Medical Center | Phase 2 |
| Unknown | Perfusion Outcomes With Near Infrared-Indocyanine Green Imaging System in Laparoscopic Total Mesorectal Excisi NCT04012645 | Zhongtao Zhang | N/A |
| Unknown | Virtual Ileostomy Versus Conventional Loop Ileostomy NCT05985252 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | N/A |
| Recruiting | Neoadjuvant Chemotherapy With PD-1 Inhibitors Combined With SIB-IMRT in the Treatment of Locally Advanced Rect NCT06017583 | Yong Zhang,MD | Phase 3 |
| Recruiting | Comparison of Postoperative Anal Function Between Parks and Bacon Techniques in Low Rectal Cancer NCT05943444 | Sixth Affiliated Hospital, Sun Yat-sen University | N/A |
| Active Not Recruiting | SCRT in TNT With or Without Chlorophyllin NCT05856305 | Tata Memorial Centre | Phase 2 |
| Recruiting | Choice of the Optimal Treatment Strategies for Mid-low REctal Cancer NCT05871762 | Peking Union Medical College Hospital | — |
| Recruiting | Study of Brain-Gut Function Reconstruction After Intersphincteric Resection for Ultra-Low Rectal Tumors NCT06082648 | Huashan Hospital | N/A |
| Recruiting | Effects of Aerobic Exercise on Skeletal Muscle Remodeling in Colorectal Cancer NCT05789433 | AdventHealth Translational Research Institute | N/A |
| Completed | Trial Comparing Loop Ileostomy Versus Loop Transverse Colostomy NCT05745909 | Republican Clinical Oncological Dispensary, Ministry of Health of the Republic of Bashkortostan | N/A |
| Unknown | Robotic Transanal Specimen Extraction Surgery Versus Robotic Transabdominal Incision Specimen Extraction Surge NCT05468944 | Taiyuan Li | N/A |
| Active Not Recruiting | Short-course Radiotherapy or Long-course Chemoradiation Followed by mFOLFOXIRI Consolidation Chemotherapy for NCT06417476 | Pei-Rong Ding | Phase 2 |
| Unknown | Neoadjuvant Arterial Embolization Chemotherapy Combined PD-1 Inhibitor for Locally Advanced Rectal Cancer NCT05420584 | The Fourth Affiliated Hospital of Zhejiang University School of Medicine | Phase 2 |
| Completed | A Prospective, Multicenter Randomized Controlled Study of the Application of Preoperative FOLFOXIRI Chemothera NCT06048146 | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | N/A |
| Recruiting | Reconstruction After Abdominoperineal Resection With Robot-assisted Harvest of VRAM Flap NCT05689775 | Oslo University Hospital | — |
| Recruiting | Neoadjuvant Chemoradiotherapy and Consolidation Chemotherapy for Rectal Cancer: A Randomized Controlled Trial NCT05496491 | Larissa University Hospital | N/A |
| Terminated | Blue and Amber Light Exposure in Patients With Rectal and Pancreatic Cancer NCT06164691 | Matthew Neal MD | N/A |
| Terminated | A Safety Study Adding Niraparib and Dostarlimab to Radiation Therapy for Rectal Cancers NCT04926324 | University of Iowa | Phase 1 / Phase 2 |
| Active Not Recruiting | Local Recurrence Due to Rectal Cancer in Sweden NCT04404777 | Sahlgrenska University Hospital | — |
| Enrolling By Invitation | Reinforced Versus Conventional Anastomosis in Laparoscopic Low Rectal Cancer Resection: A Comparative Study NCT07346534 | Shanghai 10th People's Hospital | N/A |
| Unknown | Rectal Artery Infusion Chemotherapy Combined With Anti-PD1 Antibody for MSS LARC NCT05307198 | Second Affiliated Hospital, School of Medicine, Zhejiang University | Phase 2 |
| Completed | Assessment of Complete Response MRI Criterion After Neoadjuvant Therapy in Locally Advanced Rectal Cancer NCT05534841 | Centre Hospitalier Universitaire de Nīmes | — |
| Active Not Recruiting | A Study of Atezolizumab With or Without Tiragolumab Following Neoadjuvant Chemoradiotherapy in Participants Wi NCT05009069 | Hoffmann-La Roche | Phase 2 |
| Unknown | Change of Circulating Tumor Cells During Laparoscopic or Transanal Endoscopic Surgery for Rectal Cancer. NCT05109130 | Sun Yat-sen University | — |
| Unknown | Low-dose Neuroleptanalgesia for Postoperative Delirium in Elderly Patients NCT05068180 | RenJi Hospital | Phase 4 |
| Recruiting | Intraoperative Neuromonitoring of Pelvic Autonomous Nerve Plexus During Total Mesorectal Excision NCT04949646 | Larissa University Hospital | N/A |
| Completed | TRECA - TREatment of Colorectal Adenomas and Early Colorectal CAncer in Region Västra Götaland NCT04788368 | Sahlgrenska University Hospital | — |
| Unknown | A Trial of Durvalumab (MEDI 4736) in Combination With Extended Neoadjuvant Regimens in Rectal Cancer NCT04621370 | Liz-Anne Lewsley | Phase 2 |
| Completed | Rectrospect - a Retrospective Study of Treatment Response NCT04787523 | Sahlgrenska University Hospital | — |
| Completed | Safety and Feasibility of PD-1 Blockade in the Treatment of dMMR or MSI-H Rectal Cancer NCT04357587 | Case Comprehensive Cancer Center | Phase 1 |
| Withdrawn | Single-incision Versus Conventional Laparoscopic Surgery for Colorectal Cancer NCT03633539 | Ruijin Hospital | N/A |
| Completed | Assessing the Additional Neoplasia Yield of Computer-aided Colonoscopy in a Screening Setting NCT04441580 | Fondazione Poliambulanza Istituto Ospedaliero | N/A |
| Completed | Shear Wave Elastography of Rectal Adenomas and Cancer NCT04409990 | Vejle Hospital | N/A |
| Active Not Recruiting | ctDNA-guided Surveillance for Stage III CRC, a Randomized Intervention Trial NCT04084249 | Claus Lindbjerg Andersen | N/A |
| Completed | Home-based HIIT to Improve CRC Survivorship: Feasibility and Relationship With Novel Surrogate Biomarkers of C NCT04080414 | University of Utah | N/A |
| Unknown | Exploring HIFU as a Treatment for Rectal and Other Pelvic Cancers NCT03595722 | Imperial College London | N/A |
| Completed | Treatment of Colorectal Liver Metastases With Immunotherapy and Bevacizumab NCT03698461 | Asan Medical Center | Phase 2 |
| Unknown | THREE-row Circular STAPLER in Low Anterior Resection for Rectal Cancer NCT03910699 | Russian Society of Colorectal Surgeons | N/A |
| Completed | Endoscopic Submucosal Dissection vs Local Laparoscopic Surgical Resection (TAMIS/TEO) in Early Rectal Neoplasi NCT03959839 | Dr. Alberto Herreros de Tejada Echanojáuregui | N/A |
| Completed | Peptide-based Immunization for Colon- and and Pancreas-carcinoma NCT03871790 | CENTOGENE GmbH Rostock | — |
| Unknown | Surviving Rectal Cancer at the Cost of a Colostomy International Validation of the Colostomy Impact Score NCT03516916 | Aarhus University Hospital | — |
| Recruiting | The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study NCT04075305 | UMC Utrecht | — |
| Unknown | Adjuvant Chemotherapy in Patients With Clinical Stage III Rectal Cancer Undergoing Neoadjuvant Chemoradiothera NCT03415763 | LI XIN-XIANG | Phase 3 |
| Recruiting | MRI Simulation-guided Boost in Short-course Preoperative Radiotherapy for Unresectable Rectal Cancer NCT03714490 | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | Phase 2 |
| Unknown | Organ Preservation in Locally Advanced Rectal Cancer by Radiochemotherapy Followed by Consolidation Chemothera NCT03561142 | University Hospital Tuebingen | Phase 2 |
| Unknown | Totally Neoadjuvant FOLFOXIRI + Short-course Radiation + XELOX in Patients With Locally Advanced Rectal Cancer NCT03484221 | China Medical University, China | Phase 2 |
| Recruiting | Non-operative Management for Locally Advanced Rectal Cancer NCT03179540 | Mount Sinai Hospital, Canada | N/A |
| Unknown | Robotic Assisted Transanal Total Mesorectal Excision Surgery for Rectal Cancer in Low Site NCT03422835 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | Phase 2 |
| Unknown | Robotic Versus Laparoscopic Low Anterior Resection for Rectal Cancer NCT03209076 | Instituto Nacional de Cancer, Brazil | N/A |
| Completed | Pseudo Continent Perineal Colostomy vs Permanent Left Iliac Colostomy After Abdominoperineal Resection for Ult NCT04141566 | Moroccan Society of Surgery | — |
| Completed | Evaluation of Delayed Coloanal Anastomosis NCT04248634 | Institut National d'Oncologie, Morocco | — |
| Terminated | CureOne Registry: Advanced Malignancy or Myelodysplasia, Tested by Standard Sequencing and Treated by Physicia NCT02900248 | CureOne | — |
| Unknown | The Role of Transanal Tube Drainage as A Mean of Prevention of Anastomotic Leakage Anastomotic Leakage NCT03325361 | University of Rome Tor Vergata | N/A |
| Unknown | Organ-preserving Management in Patients With Complete or Near-complete Tumour Response After Preoperative Radi NCT04095468 | Maria Sklodowska-Curie National Research Institute of Oncology | — |
| Unknown | Application of Circulating Tumor DNA Test in the Diagnosis and Treatment of Patients With Advanced Rectal Canc NCT03615170 | Zhejiang Cancer Hospital | — |
| Unknown | ESD Versus TAMIS for Early Rectal Neoplasms NCT03217773 | Chinese University of Hong Kong | N/A |
| Recruiting | "Wait-and-see" Policy for Complete Responders After Chemoradiotherapy for Rectal Cancer NCT03426397 | The Netherlands Cancer Institute | — |
| Completed | Safety and Efficacy of Atezolizumab Combined to Preoperative Radio-chemotherapy in Localized Rectal Cancer NCT03127007 | Grand Hôpital de Charleroi | Phase 1 / Phase 2 |
| Unknown | Transverse Coloplasty vs. Side-to-end Anastomosis Following Low Anterior Resection (LAR): CSAR Trial NCT03074461 | Ludwig-Maximilians - University of Munich | N/A |
| Unknown | Efficacy and Safety of a Preoperative Aerobic Exercise Program in Patients With Gastrointestinal Cancer. NCT03423056 | Instituto Nacional de Cancerologia, Columbia | N/A |
| Unknown | NEOadjuvant Chemotherapy Only Compared With Standard Treatment for Locally Advanced Rectal Cancer NCT03280407 | Zealand University Hospital | Phase 2 |
| Completed | Prospective Study Evaluating the Feasibility of Fiducial Markers Placement for Patients With Esophageal or Rec NCT03057288 | Société Française d'Endoscopie Digestive | N/A |
| Recruiting | Watch and Wait as Treatment for Patients With Rectal Cancer NCT03125343 | Sahlgrenska University Hospital | N/A |
| Completed | PET/MR for Staging Rectal Cancer Patients With and Without EMVI-MR NCT02537340 | Instituto do Cancer do Estado de São Paulo | — |
| Unknown | Sentinel Lymph Node Mapping in Rectal Cancer NCT02869152 | University of Virginia | N/A |
| Terminated | Tumor Hypoxia With HX4 PET in Several Diseases NCT02584400 | Maastricht Radiation Oncology | Phase 2 |
| Completed | Clinical Relevance of Major Pathologic Regression for Locally Advanced Rectal Cancer NCT06879197 | Yanhong Deng | — |
| Unknown | A Prospective Clinical Study for Laparoscopic D3 Dissection With Preservation of Left Colic Artery in Rectal C NCT02753465 | Fudan University | N/A |
| Completed | Timing of Rectal Cancer Resection After Preoperative Chemoradiotherapy NCT02441153 | Health Sciences North Research Institute | — |
| Completed | Individual Follow-up After Rectal Cancer - Focus on the Needs of the Patient NCT03622437 | Aarhus University Hospital | N/A |
| Unknown | Trial of Robotic Versus Laparoscopic-assisted Radical Resection for Rectal Cancer NCT02673177 | Southwest Hospital, China | N/A |
| Completed | Use of the TDT for Prevention of Anastomotic Leakage After Laparoscopic Anterior Resection for Rectal Cancer NCT02686567 | Third Military Medical University | N/A |
| Unknown | Predicting Neoadjuvant Therapy Response of Rectal Cancer With MRI NCT02640586 | Sun Ying-Shi | N/A |
| Unknown | Detection of CTCs in Stage III Rectal Cancer Patients Undergoing Neoadjuvant Therapy NCT02554448 | Sixth Affiliated Hospital, Sun Yat-sen University | N/A |
| Unknown | Rectal Sparing Approach After Preoperative Radio and/or Chemotherapy in Patients With Rectal Cancer NCT02710812 | University of Padova | — |
| Unknown | The Role of Indocyanine Green (ICG) Fluorescence Imaging on Anastomotic Leak in Robotic Colorectal Surgery NCT02598414 | Acibadem University | Phase 2 / Phase 3 |
| Terminated | Exercise Training for Rectal Cancer Patients NCT02538913 | Norwegian University of Science and Technology | N/A |
| Unknown | A Prospective Clinical Study for Transanal Double Purse-string Rectal Anastomosis Preformed With KOL Stapler NCT02565667 | Fudan University | N/A |
| Unknown | Prediction of Response to Neoadjuvant Therapy in Rectal Cancer NCT02439086 | Colchester General Hospital | N/A |
| Unknown | Mri IN STaging REctal Polyp Planes NCT02532803 | Royal Marsden NHS Foundation Trust | N/A |
| Terminated | Neoadjuvant Metformin in Association to Chemoradiotherapy for Locally Advanced Rectal Cancer NCT02473094 | University of Campinas, Brazil | Phase 2 |
| Active Not Recruiting | Safety of a Boost (CXB or EBRT) in Combination With Neoadjuvant Chemoradiotherapy for Early Rectal Adenocarcin NCT02505750 | Centre Antoine Lacassagne | Phase 3 |
| Unknown | Nano MRI on 7 Tesla in Rectal and Breast Cancer NCT02751606 | Radboud University Medical Center | Phase 3 |
| Completed | Induction Chemotherapy Before or After Preoperative Chemoradiotherapy and Surgery for Locally Advanced Rectal NCT02363374 | Prof. Dr. med. Claus Rödel | Phase 2 |
| Completed | Clinical Outcomes and Prognostic Factors of Robotic Assisted Rectal Cancer Resection Alone vs. Robotic Rectal NCT04265417 | Taiyuan Li | — |
| Completed | Irreversible Electroporation(IRE) For Unresectable Rectal Neoplasms NCT02425059 | Fuda Cancer Hospital, Guangzhou | N/A |
| Completed | Incidence, Risk Factor, Treatment and Overall Survival of Locally Recurrent Rectal Cancer NCT05475301 | Radboud University Medical Center | — |
| Completed | Fish Oil Supplement in Rectal Cancer NCT02534389 | AC Camargo Cancer Center | N/A |
| Unknown | Selinexor Combined With Standard Chemoradiation as Neoadjuvant Treatment in Locally Advanced Rectal Cancer NCT02137356 | Sheba Medical Center | Phase 1 |
| Recruiting | Development of a Clinical and Biological Database in Rectum Cancer NCT04006951 | Institut du Cancer de Montpellier - Val d'Aurelle | N/A |
| Completed | Transanal Total Mesorectal Excision Versus Laparoscopic TME for Rectal Cancer NCT02252250 | Third Military Medical University | N/A |
| Completed | Predicting RadIotherapy ReSponse of Rectal Cancer With MRI and PET NCT02233374 | Royal North Shore Hospital | N/A |
| Unknown | CONVERT: Neoadjuvant Chemotherapy Alone Versus Preoperative Chemoradiation for Locally Advanced Rectal Cancer NCT02288195 | Sun Yat-sen University | Phase 3 |
| Unknown | Preoperative Chemoradiation Followed by Chemotherapy for Locally Advanced Rectal Cancer NCT01952951 | National Cancer Center, Korea | Phase 2 |
| Terminated | Gene Expression and FDG PET/MRI in Evaluating Treatment Response in Patients With Locally Advanced Rectal Canc NCT02112162 | Washington University School of Medicine | Phase 1 |
| Unknown | Functional Outcome of Organ Preservation After Neo-adjuvant Chemo Radiation for Rectal Cancer NCT02278653 | Maastricht University Medical Center | — |
| Completed | Endoscopically Assisted Colostomy With Colopexy for Critically Ill Patients Without General Anesthesia or Lapa NCT02308631 | University of Sao Paulo | Phase 1 |
| Completed | Use of One Kind of Controllable Tube Ileostomy in the Low Rectal Cancer NCT02012023 | First Affiliated Hospital of Zhejiang University | N/A |
| Completed | Cancer and Anesthesia: Survival After Radical Surgery - a Comparison Between Propofol or Sevoflurane Anesthesi NCT01975064 | Uppsala University | Phase 4 |
| Completed | Ex Vivo Intra-arterial Indigo Carmine Injection After Transanal Total Mesorectal Excision NCT04455737 | Walter Brunner | — |
| Completed | Functional MRI of Hypoxia-mediated Rectal Cancer Aggressiveness NCT01816607 | University Hospital, Akershus | — |
| Completed | Clinical Relevance of the Salvage Treatment for Colorectal Neuroendocrine Tumors NCT06143605 | Yanhong Deng | — |
| Completed | [F-18] Fluorothymidine PET/CT Imaging for Pelvic Cancers NCT01717391 | John M. Buatti | Phase 2 |
| Completed | Diagnostic Value of Novel MR Imaging Techniques for the Primary Staging and Restaging of Rectal Cancer NCT01721785 | Maastricht University Medical Center | — |
| Terminated | A Trial of Dalotuzumab in Combination With Irinotecan Versus Cetuximab and Irinotecan for Participants With Me NCT01609231 | Merck Sharp & Dohme LLC | Phase 2 |
| Withdrawn | Transanal Endoscopic Microsurgery Versus Endoscopic Submucosal Dissection For Large Rectal Adenomas NCT01023984 | European Association for Endoscopic Surgery | Phase 4 |
| Terminated | Alkagin Paste in the Prevention of Radiation Dermatitis NCT01408407 | Dr. Te Vuong | Phase 2 |
| Terminated | Effective Study of Preoperative Short-course Radiotherapy for the Advanced Resectable Rectal Cancer NCT01437514 | West China Hospital | Phase 2 / Phase 3 |
| Terminated | Maintenance Chemotherapy After Neoadjuvant Chemoradiation Therapy for Distal Rectal Cancer NCT01613469 | Marks, John, M.D. | Phase 2 |
| Completed | Safety Study of Capecitabine With Radiation in Elderly Rectal Cancer NCT01584544 | Chinese Academy of Medical Sciences | Phase 1 |
| Unknown | Defunctioning Cannula Ileostomy After Lower Anterior Resection of Rectal Cancer NCT01980238 | First Affiliated Hospital of Zhejiang University | N/A |
| Completed | Study of Postoperative Concurrent Chemo-radiation With Capecitabine in Elderly Rectal Cancer Patients NCT01268943 | Chinese Academy of Medical Sciences | Phase 1 |
| Active Not Recruiting | Assessment of Response Before, During and After Neoadjuvant Chemoradiotherapy in Rectal Cancer Patients NCT01171300 | Universitaire Ziekenhuizen KU Leuven | N/A |
| Completed | Fluorescent Evaluation of Colorectal Anastamoses NCT01424293 | Maimonides Medical Center | N/A |
| Completed | Preoperative Chemoradiation With VMAT-SIB in Rectal Cancer NCT02745639 | IRCCS Azienda Ospedaliero-Universitaria di Bologna | Phase 2 |
| Completed | Five Fractions of Radiotherapy Followed by Full Dose FOLFOX Chemotherapy as Preoperative Treatment for Rectal NCT01060007 | Washington University School of Medicine | Phase 2 |
| Completed | Symptoms and Quality of Life (QoL) After Palliative Pelvic Radiation of Prostate and Rectal Cancers NCT01023529 | Sorlandet Hospital HF | — |
| Completed | The Effect of Case Management in Complex Cancer Pathways NCT00845247 | University of Aarhus | N/A |
| Terminated | Neo-Adjuvant FOLFOX for Rectal Carcinoma NCT00832299 | Beth Israel Medical Center | Phase 2 |
| Completed | NITI CAR27 (ColonRing) Compression Anastomosis in Colorectal Surgery NCT01056913 | St John of God Hospital, Vienna | Phase 4 |
| Terminated | Diverting Loop Ileostomy: With or Without Rod NCT00959738 | Insel Gruppe AG, University Hospital Bern | N/A |
| Unknown | Adjuvant Treatment of Concurrent RT and CAPOX or Capecitabine Alone for Stage II and III Rectal Cancer NCT00714077 | Chinese Academy of Medical Sciences | — |
| Completed | First-Line Bevacizumab and Chemotherapy in Metastatic Cancer of the Colon or Rectum - International Study NCT00537901 | King Faisal Specialist Hospital & Research Center | N/A |
| Completed | Concentration of Ertapenem in Colorectal Tissue NCT00535652 | University of Ulm | Phase 4 |
| Completed | Pilot Trial of Pre-operative Chemo/RT Using Xeloda and External Beam RT Followed by Definite Surgery in Patien NCT00535041 | King Faisal Specialist Hospital & Research Center | N/A |
| Completed | Local Excision in Downstaged Rectal Cancer NCT00427375 | University Hospital, Bordeaux | Phase 3 |
| Unknown | XELOX+Bevacizumab Followed by Capecitabine+Bevacizumab+Radiotherapy as Neoadjuvant Treatment of Locally Advanc NCT00557713 | Associacio catalana per a la recerca oncologica i les seves implicacions sanitaries i socials | Phase 2 |
| Completed | The Role of Biofeedback in Improving Continence After Anterior Resection NCT00515853 | University of Southampton | N/A |
| Completed | Neoadjuvant Chemoradiotherapy and Adjuvant Chemotherapy With 5-Fluorouracil and Oxaliplatin Versus 5-Fluoroura NCT00349076 | University of Erlangen-Nürnberg Medical School | Phase 3 |
| Completed | A Study of Pemetrexed and Folic Acid Given Before Surgery (Neoadjuvant Treatment) to Patients With Rectal Canc NCT00330915 | Eli Lilly and Company | Phase 2 |
| Unknown | Preoperative Chemoradiotherapy With Cetuximab in Rectal Cancer NCT00506844 | National Cancer Center, Korea | Phase 2 |
| Completed | Study of Neoadjuvant Chemotherapeutic Treatment (XELOX) Followed by Chemoradiotherapy (XELOX/RT) and Surgery V NCT00421824 | Sanofi | Phase 2 |
| Unknown | Genetic Profile on Predicting Sensibility of Preoperative Chemoradiotherapy on Locally Advanced Rectal Carcino NCT01930942 | Chinese Academy of Medical Sciences | Phase 2 |
| Terminated | Endoscopic Posterior Mesorectal Resection in T1 Rectal Cancer NCT00531297 | Cantonal Hospital of St. Gallen | N/A |
| Completed | Concurrent Chemoradiation With Concomitant Boost In Locally Advanced Rectal Cancer NCT02723253 | IRCCS Azienda Ospedaliero-Universitaria di Bologna | Phase 2 |
| Completed | Predictive Factors of Disease-free Survival After Complete Pathological Response to Neoadjuvant Radiotherapy i NCT03601689 | Moroccan Society of Surgery | — |
| Completed | Anterior Perineal Plane for Ultra Low Anterior Resection of the Rectum NCT00534131 | Queen Mary University of London | N/A |
| Completed | Palliative Short-Course Radiotherapy in Rectal Cancer NCT02639403 | IRCCS Azienda Ospedaliero-Universitaria di Bologna | Phase 2 |
| Completed | CORE: Capecitabine, Oxaliplatin, Radiotherapy and Excision NCT00174616 | Sanofi | Phase 2 |
| Completed | Mesorectal Excision (ME) Versus ME With Lateral Node Dissection for Stage II, III Lower Rectal Cancer (JCOG021 NCT00190541 | Haruhiko Fukuda | Phase 3 |
| Completed | Study of Oxaliplatin/5-FU/Leucovorin Plus Vatalanib Versus Oxaliplatin/5-FU/Leucovorin in Patients With Metast NCT00056459 | Novartis | Phase 3 |
| Completed | Study of Oxaliplatin/5-FU/Leucovorin Plus Vatalanib Versus Oxaliplatin/5-FU/Leucovorin in Patients With Previo NCT00056446 | Novartis Pharmaceuticals | Phase 3 |
| Terminated | Oxaliplatin in Rectal Cancer NCT00259363 | Sanofi | Phase 1 / Phase 2 |
| Completed | Preoperative Radiotherapy/ Oxaliplatin/ Capecitabine Treatment For Unresectable Locally-advanced Rectal Cancer NCT00263029 | Sanofi | Phase 2 |
| Completed | Study of the Efficacy and Safety of Epoetin Alfa Administered Weekly in Patients With Gastric or Rectal Cancer NCT00036400 | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | Phase 3 |
| Completed | A Phase I Study of Oral Topotecan as a Radiosensitizing Agent in Patients With Rectal Carcinoma NCT00215956 | H. Lee Moffitt Cancer Center and Research Institute | Phase 1 |
| Completed | Evaluation of the Neoadjuvant Treatment With Oxaliplatin -UFT- Radiotherapy in Rectal Cancer NCT00403624 | Sanofi | Phase 1 / Phase 2 |
| Completed | Preoperative Combined Radiation and Chemotherapy - Rectal Cancer NCT00232453 | University Health Network, Toronto | Phase 2 |
| Completed | Study Evaluating MAC-321 in Colorectal Cancer NCT00063427 | Wyeth is now a wholly owned subsidiary of Pfizer | Phase 2 |
| Completed | Study Evaluating EKB-569 in Advanced Colorectal Cancer NCT00072748 | Wyeth is now a wholly owned subsidiary of Pfizer | Phase 2 |