NCT00535652

Concentration of Ertapenem in Colorectal Tissue

Konzentrationen Von Ertapenem in Kolorektalem Gewebe

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 23 (actual)
• Sponsor: University of Ulm · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine the tissue kinetics of ertapenem in colonic tissue from three hours up to six hours (25% of dosing interval) after administration of ertapenem.

Detailed description

The purpose of this study is to determine the tissue kinetics of ertapenem in colorectal tissue from three hours up to six hours (25% of dosing interval) after administration of ertapenem before an elective surgical intervention (open or laparoscopic surgery) at the colon/rectum. Subjects are patients. Hospitalized patients 18 years or older requiring elective surgical intervention (open or laparoscopic surgery) at the colon will be eligible for this study.

Conditions

• Diverticulosis, Colonic
• Rectal Neoplasms
• Colonic Neoplasms

Interventions

Type	Name	Description
DRUG	Ertapenem	powder for infusion, 1 gram I.V., single dose over 30 min.

Timeline

• Start date: 2007-09-01
• Primary completion: 2009-12-01
• Completion: 2009-12-01
• First posted: 2007-09-26
• Last updated: 2017-02-10
• Results posted: 2016-12-16

Locations

1 site across 1 country: Germany