NCT00190541

Mesorectal Excision (ME) Versus ME With Lateral Node Dissection for Stage II, III Lower Rectal Cancer (JCOG0212)

Mesorectal Excision With Lateral Lymph Node Dissection Versus Without Lateral Lymph Node Dissection for Clinical Stage II, III Lower Rectal Cancer (JCOG0212)

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 700 (actual)
• Sponsor: Haruhiko Fukuda · Academic / Other
• Sex: All
• Age: 21 Years – 74 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate the of international standard operation, mesorectal excision (ME alone) compared to Japanese standard operation, ME with lateral lymph node dissection for clinical stage II, III lower rectal cancer

Detailed description

Total mesorectal excision (TME) or mesorectal excision (ME) with lateral lymph node dissection for advanced rectal cancer is widely performed in Japan. In other countries, TME or ME without lateral lymph node dissection is the standard. In order to determine which is the better rectal cancer surgery, relapse-free survivals of these are compared as the primary endpoint.

Conditions

• Rectal Neoplasms

Interventions

Type	Name	Description
PROCEDURE	Mesorectal excision with lateral lymph node dissection	Mesorectal excision with lateral lymph node dissection
PROCEDURE	Mesorectal excision without lateral lymph node excision	Mesorectal excision without lateral lymph node excision

Timeline

• Start date: 2003-06-01
• Primary completion: 2015-06-01
• Completion: 2015-06-01
• First posted: 2005-09-19
• Last updated: 2016-09-22

Locations

48 sites across 1 country: Japan