Trials / Terminated
TerminatedNCT02900248
CureOne Registry: Advanced Malignancy or Myelodysplasia, Tested by Standard Sequencing and Treated by Physician Choice
Patients Diagnosed With Advanced Malignancy or Myelodysplasia, Tested by Standardized Sequencing, and Treated by Physician-Determined Care Plan: A CureOne Observational Registry (N1)
- Status
- Terminated
- Phase
- —
- Study type
- Observational
- Enrollment
- 23 (actual)
- Sponsor
- CureOne · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Registry participants with advanced malignancy or myelodysplasia will have a sample of their tumor or tissue analysed for genetic alterations using next generation sequencing (NGS) performed in a lab that has been certified to meet a high quality standard. Treatments and outcomes will be reported to the registry to allow further understanding of how genetic differences can lead to better diagnosis and treatments.
Detailed description
Every malignancy or myelodysplasia is different on a molecular (genetic) level even in patients with the same diagnosis. These differences often give prognostic information, determine what types of treatments are available for a patient, as well as determine outcomes. In this registry, the method of identifying the genetic difference of the disease (using Next Generation Sequencing or NGS) is standardized, the treatments received by a patient, and the outcome of these treatments are entered into a database where all identifying information is removed. Payers (insurance companies) or others will generally pay for the testing, laboratories will report the genetic information, physicians and eventually patients will report treatments and outcomes. This information will then be reviewed frequently and analyzed to find better methods to improve the testing or treatments of disease. It is expected that dozens of other trials or registries will eventually be available for participants.
Conditions
- Neoplasms
- Lung Neoplasms
- Colon Neoplasms
- Breast Neoplasms
- Pancreatic Neoplasms
- Prostate Neoplasms
- Kidney Neoplasms
- Liver Neoplasms
- Rectal Neoplasms
- Hematologic Neoplasms
- Multiple Myeloma
- Myelodysplastic Syndromes
- Ovarian Neoplasms
- Bladder Neoplasms
- Testicular Neoplasms
- Endometrial Neoplasms
- Brain Neoplasms
- Biliary Tract Neoplasms
- Head and Neck Neoplasms
- Uterine Cervical Neoplasms
- Skin Neoplasms
- Melanoma
- Gastric Neoplasms
- Anal Neoplasms
- Sarcoma
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Provider determined | Provider will treat patient as he/she feels best |
Timeline
- Start date
- 2017-10-02
- Primary completion
- 2019-03-29
- Completion
- 2019-03-29
- First posted
- 2016-09-14
- Last updated
- 2019-04-02
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT02900248. Inclusion in this directory is not an endorsement.