| Not Yet Recruiting | A Single Ascending Dose Study of SYH2082 Injection in Healthy Participants NCT07532655 | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | Phase 1 |
| Not Yet Recruiting | Effect of the Thrive AI Health App on Lifestyle Behaviors and Quality of Life NCT07376655 | Yale University | N/A |
| Recruiting | A Study of Multiple Doses of Orally Administered RO7795081 in Otherwise Healthy Chinese Adult Participants Wit NCT07499050 | Hoffmann-La Roche | Phase 1 |
| Recruiting | Study of Olatorepatide in Adult Participants Living With Overweight or Obesity in the US NCT07431086 | Regeneron Pharmaceuticals | Phase 2 |
| Recruiting | Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or O NCT07353931 | Eli Lilly and Company | Phase 3 |
| Not Yet Recruiting | A Phase III Study to Evaluate the Efficacy and Safety of MDR-001 in Adult Participants With Overweight or Obes NCT07274137 | MindRank AI Ltd | Phase 3 |
| Recruiting | Extension Study of the Phase 3 Clinical Study of GZR18 Injection for Weight Loss NCT07292441 | Gan & Lee Pharmaceuticals. | Phase 3 |
| Recruiting | A Study of BGM1812 Injection in Healthy and Non-diabetic Overweight or Obese Chinese Participants NCT07294235 | BrightGene Bio-Medical Technology Co., Ltd. | Phase 1 |
| Recruiting | Relative Bioavailability of First vs Second-Generation Formulations of HRS9531 Tablets in Obese or Overweight NCT07150962 | Fujian Shengdi Pharmaceutical Co., Ltd. | Phase 1 |
| Recruiting | Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of BGM1812 Injection Following Single NCT07224399 | BrightGene Bio-Medical Technology Co., Ltd. | Phase 1 |
| Active Not Recruiting | A Study of IBI3032 in Chinese Participants With Overweight or Obesity NCT07170319 | Innovent Biologics Technology Limited (Shanghai R&D Center) | Phase 1 |
| Recruiting | The Efficacy and Safety of Metformin Intervention in Elderly Overweight or Obesity With Mild Cognitive Impairm NCT07395960 | Fudan University | Phase 1 / Phase 2 |
| Recruiting | A Study of LY4064912 in Healthy Participants and With Overweight or Obesity NCT07152002 | Eli Lilly and Company | Phase 1 |
| Not Yet Recruiting | Effectiveness of a Digital Behavioral Intervention Program for Overweight and Obese Patients NCT07045272 | Anhui Medical University | N/A |
| Not Yet Recruiting | Efficacy of Satisens® in Reducing Emotional Eating NCT07079046 | José Enrique de la Rubia Ortí, Ph | N/A |
| Recruiting | Healthy Living BEYOND Weight Study NCT07075341 | American Heart Association | — |
| Recruiting | A Study to Evaluate MWN109 Tablets in Healthy Adult Participants NCT06938269 | Shanghai Minwei Biotechnology Co., Ltd | Phase 1 |
| Recruiting | Remotely Delivered Resistance Training for Cardiometabolic Health Among Black Women NCT06360536 | University of Alabama at Birmingham | N/A |
| Not Yet Recruiting | Acute Impact of Whey Protein-enriched Milk Fat Globule Membrane Supplementation on Postprandial Markers of Hea NCT06953232 | Loughborough University | N/A |
| Recruiting | Weight Reduction in CLBP NCT04824248 | Vrije Universiteit Brussel | N/A |
| Recruiting | A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweigh NCT06948435 | Eli Lilly and Company | Phase 3 |
| Completed | The Effect of AMG 133 on Gastric Emptying NCT07429032 | Amgen | Phase 1 |
| Recruiting | A Study of HS-20094 in Overweight or Obese Participants NCT07057674 | Jiangsu Hansoh Pharmaceutical Co., Ltd. | Phase 1 |
| Enrolling By Invitation | Effect of Mediterranean Diet Combined With Intermittent Fasting on Liver Fibrosis Compared to Naltrexone/Bupro NCT06845345 | Carmen Dietvorst | Phase 4 |
| Recruiting | Semaglutide for Metabolic Intervention and Adipose Loss to Treat Atrial Fibrillation NCT06499857 | University of Chicago | Phase 3 |
| Active Not Recruiting | A Phase 2b Study to Evaluate the Efficacy and Safety of Once-Monthly MET097 in Adults With Obesity or Overweig NCT06973720 | Metsera, a wholly owned subsidiary of Pfizer | Phase 2 |
| Not Yet Recruiting | Pylorus Distensibility Measurement NCT06908551 | BariaTek Medical | — |
| Recruiting | eMOTION: Examining Implicit Attitudes in Physical Activity Engagement NCT07044570 | University of Southern California | — |
| Recruiting | A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439 NCT06857942 | Eli Lilly and Company | Phase 4 |
| Completed | A Clinical Study to Evaluate the Efficacy, Safety, and Tolerability of TERN-601 in Adults With Overweight or O NCT06854952 | Terns, Inc. | Phase 2 |
| Recruiting | A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Ac NCT06864026 | Eli Lilly and Company | Phase 4 |
| Recruiting | The Safety, Tolerability, and Pharmacokinetics of of SYH9017 in Chinese Participants With Overweight and Obesi NCT06830343 | CSPC Baike (Shandong) Biopharmaceutical Co., Ltd. | Phase 1 |
| Enrolling By Invitation | An Innovative Care Model Integrating Mobile Health Support to Promote Weight Management in Adults With Overwei NCT06996431 | The University of Hong Kong | N/A |
| Recruiting | A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HRS-4729 Injection in H NCT06762600 | Fujian Shengdi Pharmaceutical Co., Ltd. | Phase 1 |
| Enrolling By Invitation | Effect of Psiguavin for Obesity Treatment (PSIGUAVIN) NCT06512818 | Universidad Católica San Antonio de Murcia | Phase 1 / Phase 2 |
| Recruiting | Craving Network Neurofeedback NCT06426693 | Yale University | N/A |
| Active Not Recruiting | A Study of Safety and Tolerability of Multiple Doses of HRS-7535 in Obese Subjects NCT06621316 | Shandong Suncadia Medicine Co., Ltd. | Phase 1 / Phase 2 |
| Recruiting | A Study of BGM0504 Injection in Participants with Obesity or Overweight NCT06704581 | BrightGene New Bio-Medical Technology(Wuxi) Co.Ltd. | Phase 3 |
| Active Not Recruiting | A Phase 2b Study to Examine the Safety and Efficacy of Once-Weekly MET097 in Adults With Obesity or Overweight NCT06712836 | Metsera, a wholly owned subsidiary of Pfizer | Phase 2 |
| Active Not Recruiting | A Master Protocol for Orforglipron in Participants With Obstructive Sleep Apnea and Obesity or Overweight NCT06649045 | Eli Lilly and Company | Phase 3 |
| Completed | Effect of Akkermansia Muciniphila Akk11 on Metabolic and Gut Health in Overweight and Obese Subjects NCT06653101 | Wecare Probiotics Co., Ltd. | N/A |
| Recruiting | The Effects of Tirzepatide in People With Overweight/Obesity and Coronary Artery Disease NCT06606821 | Tina Vilsbøll | Phase 4 |
| Recruiting | Effect of Low-calorie Diets With Different Macronutrient Composition and Macronutrient Distribution in Shift W NCT06912555 | Universidad de Zaragoza | N/A |
| Completed | A Study of ZT002 Injection With Subjects With Overweight or Obesity NCT07020884 | Beijing QL Biopharmaceutical Co.,Ltd | Phase 2 |
| Recruiting | eMOTION: Examining Affective Mechanisms in Physical Activity Engagement NCT06570642 | University of Southern California | N/A |
| Recruiting | A Study to Evaluate Features of KN069 in Participants With Obesity or Overweight NCT06547775 | Suzhou Alphamab Co., Ltd. | Phase 1 |
| Completed | To Compare the Efficacy and Safety of HRS9531 and Placebo in Subjects With Overweight or Obese NCT06396429 | Fujian Shengdi Pharmaceutical Co., Ltd. | Phase 3 |
| Completed | Phase 1 to Study Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of NA-931 in Obese Participants NCT06615700 | Biomed Industries, Inc. | Phase 1 |
| Completed | DPP Feasibility Study of Breastfeeding - eMOMS 2.0 NCT06372860 | University of Kansas Medical Center | N/A |
| Completed | A Study of the Efficacy and Safety of Efsubaglutide Alfa in Overweight or Obesity Patients NCT06732960 | Shanghai Yinnuo Pharmaceutical Technology Co., Ltd. | Phase 2 |
| Completed | Localized Body Cooling Technology on Sleep and Metabolism in African, American With Overweight and Obesity NCT05849181 | University of Chicago | N/A |
| Completed | Probiotic Influence on Obesity-Related Lipidemia NCT06305650 | Wecare Probiotics Co., Ltd. | N/A |
| Completed | Binge Eating Self-help for Teens ONLINE Pilot and Feasibility Study NCT06107387 | Yale University | N/A |
| Unknown | Development of PI-ML Algorithm for Prediction of the Real-time Risk for Developing Pre-diabetes NCT06195566 | Jelizaveta Sokolovska | — |
| Unknown | Effects of Different ''Exercise Snacking'' Modalities on Glycemic Control in Patients With Type 2 Diabetes NCT06146036 | University of Nis | N/A |
| Completed | Sleep Extension or Regularity to Reduce Diabetes Risk NCT06128265 | University of Chicago | N/A |
| Recruiting | The Effects of Remimazolam on the Incidence of Severe Hypoxia During Sedated Hysteroscopy for Assisted Reprodu NCT06187896 | RenJi Hospital | N/A |
| Completed | A Study of TG103 Injection in Non-diabetic Overweight or Obesity NCT05997576 | CSPC Baike (Shandong) Biopharmaceutical Co., Ltd. | Phase 3 |
| Completed | A Study of ZT002 Injection in Participants With Overweight or Obesity NCT06371326 | Beijing QL Biopharmaceutical Co.,Ltd | Phase 1 |
| Recruiting | The Acute T-Rex (Timing of Resistance Exercise) Study NCT06366399 | University of Utah | N/A |
| Unknown | Differences in Postprandial Glucose Changes NCT05957224 | The University of The West Indies | N/A |
| Recruiting | Postprandial Effects of Animal Versus Plant-Based Protein NCT06445296 | Ball State University | N/A |
| Completed | Thread Embedding Acupuncture Combined With Auricular Acupuncture for Overweight and Obesity NCT06091761 | University of Medicine and Pharmacy at Ho Chi Minh City | N/A |
| Completed | A Study of BGM0504 Evaluating Weight Loss in Overweight or Obese Chinese Subjects NCT06973681 | BrightGene Bio-Medical Technology Co., Ltd. | Phase 2 |
| Unknown | Efficacy of Pigmented Rice on Reducing Cardiometabolic Risk Factors Among Filipino Adults NCT06092632 | University of Santo Tomas | N/A |
| Completed | eMOTION Formative Study NCT06125964 | University of Southern California | N/A |
| Completed | Multicenter Trial Investigating Performance and Safety of the Medical Device SiPore21® NCT06087822 | Sigrid Therapeutics AB | N/A |
| Unknown | Efficacy and Safety of HRS9531 Injections in Overweight or Obese Subjects NCT06054698 | Fujian Shengdi Pharmaceutical Co., Ltd. | Phase 2 |
| Unknown | A Phase 1 Study to Evaluate EMP22 PD and EMP16 PK Versus Xenical® in Healthy Volunteers NCT06013163 | Empros Pharma AB | Phase 1 |
| Completed | National Survey of Young Adult Nutrition NCT06096636 | USDA Grand Forks Human Nutrition Research Center | — |
| Not Yet Recruiting | The Effects of Remimazolam on the Incidence of Hypoxia During Sedated Hysteroscopy for Assisted Reproduction i NCT06004843 | RenJi Hospital | N/A |
| Completed | A Study of Retatrutide (LY3437943) on Renal Function in Participants With Overweight or Obesity and Chronic Ki NCT05936151 | Eli Lilly and Company | Phase 2 |
| Active Not Recruiting | Biological Sample Repository for Gastrointestinal Disorders NCT05874726 | Pichamol Jirapinyo, MD, MPH | — |
| Completed | Efficacy and Safety of HRS9531 Injection in Obese Subjects Without Diabetes NCT05881837 | Fujian Shengdi Pharmaceutical Co., Ltd. | Phase 2 |
| Active Not Recruiting | A Study of Orforglipron (LY3502970) in Adult Participants With Obesity or Overweight With Weight-Related Comor NCT05869903 | Eli Lilly and Company | Phase 3 |
| Enrolling By Invitation | PA Moves Trial - Patient Participants NCT05227105 | University of Pittsburgh | N/A |
| Completed | Phase 1 Study of CT-996 in Overweight/Obese Participants and Patients With Type 2 Diabetes Mellitus NCT05814107 | Carmot Australia First Pty Ltd | Phase 1 |
| Unknown | Hypocaloric Mediterranean Diet or Physical Activity to Lower Cardiometabolic Risk NCT04155112 | Oslo University Hospital | N/A |
| Unknown | Study Exploring the Supportive Effect of Acarbose in Weight Management NCT05934110 | Empros Pharma AB | Phase 2 |
| Active Not Recruiting | Functional Fitness for Overweight or Obese Adults with Mobility Disabilities NCT05880966 | University of Kansas | N/A |
| Recruiting | Lifestyle Intervention in Overweight/Obese Chronic Low Back Pain (CLBP) Patients: an International Multi-cente NCT05811624 | Vrije Universiteit Brussel | N/A |
| Recruiting | NDPP-NextGen: A Clinical Trial to Reduce Intergenerational Obesity and Diabetes Risks NCT05674799 | Wake Forest University Health Sciences | N/A |
| Completed | A Study of Daily Oral Orforglipron (LY3502970) Compared With Insulin Glargine in Participants With Type 2 Diab NCT05803421 | Eli Lilly and Company | Phase 3 |
| Completed | Indigenous Supported Agriculture "Go Healthy" NCT05773833 | Oklahoma State University Center for Health Sciences | N/A |
| Completed | Cognitive Behavioral Therapy for Adolescents With Bulimia Nervosa and Higher Weight (Online Treatment Study) NCT05770947 | Yale University | N/A |
| Completed | Phase 1b/2a Study of GSBR-1290 in Adult Overweight or Obese Healthy Subjects and Subjects With Type 2 Diabetes NCT05762471 | Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics | Phase 1 / Phase 2 |
| Recruiting | Taxi ROADmAP (Realizing Optimization Around Diet And Physical Activity) NCT05770570 | Memorial Sloan Kettering Cancer Center | Phase 2 |
| Completed | Latino Semaglutide Study NCT05087342 | Loma Linda University | Phase 3 |
| Completed | Safety and Efficacy of Bimagrumab and Semaglutide in Adults Who Are Overweight or Obese NCT05616013 | Eli Lilly and Company | Phase 2 |
| Completed | Physical Exercise in Obesity for Health and Quality of Life. NCT05713461 | Universidad Pablo de Olavide | N/A |
| Completed | T2DM Intensity Lifestyle Intervention NCT05561855 | Ningbo No. 1 Hospital | N/A |
| Recruiting | Better Lifestyle Counseling for African American Women During Pregnancy NCT05234125 | University of Illinois at Chicago | N/A |
| Completed | A 6-month Observational Study on Combined Oral Contraceptives and Body Weight in Pre-Menopausal Women With Ove NCT05061472 | University of Colorado, Denver | — |
| Unknown | A Study of TG103 Injection in Overweight or Obesity NCT05299697 | CSPC Baike (Shandong) Biopharmaceutical Co., Ltd. | Phase 2 |
| Completed | β-alanine Supplementation in Adults With Overweight/Obesity NCT05329610 | Nottingham Trent University | N/A |
| Completed | The KING'S WHOLE Feasibility Study NCT05273892 | King's College London | N/A |
| Completed | Metabolic Effects of Oral Sodium Butyrate Supplementation on Overweight Individuals NCT06247020 | Federico II University | N/A |
| Unknown | Lived Experience of Overweight/Obese Patients Who Have Benefited From a Mindful Eating Program. NCT05248607 | University Hospital, Montpellier | — |
| Withdrawn | Healthy Hearts: Leveraging the Diabetes Prevention Program to Decrease Health Disparities in Women of Reproduc NCT05379296 | The University of Texas Medical Branch, Galveston | N/A |
| Completed | Effect of a Modified 5:2 Intermittent Fasting Diet on Population With Overweight or Obesity in China NCT06552403 | Zhejiang Provincial Tongde Hospital | N/A |
| Unknown | Home Based or Traditional Class HIIT in Overweight Women. NCT04796532 | University of Évora | N/A |
| Completed | A Virtual Cardiometabolic Health Program for African Immigrants: The Afro-DPP Program NCT05144737 | Johns Hopkins University | N/A |
| Active Not Recruiting | Cardiovascular and InflammAging Study NCT04763291 | Green Beat | N/A |
| Completed | Understanding Variability in Behavioral Weight Loss Treatment Response in Young Women (Ready SET Health) NCT04875091 | Virginia Commonwealth University | N/A |
| Completed | HIIT on Overweight Middle-aged Adults NCT06383442 | Taipei Medical University | N/A |
| Unknown | Soy Peptide, Conjugated Linoleic Acid, Overweight or Obese, Body Composition NCT04728399 | Fangfang Zeng | N/A |
| Unknown | The Effects of Glucose Control and Weight Loss Between Beinaglutide and Dulaglutide in Type 2 Diabetes With Ov NCT05005741 | Second Xiangya Hospital of Central South University | Phase 4 |
| Active Not Recruiting | Technology-Supported Treatment of Sleep Apnea in Prediabetes NCT04225507 | University of Chicago | N/A |
| Completed | Supporting Lifestyle Change in Obese Pregnant Mothers Through Wearable Internet-of-Things (SLIM) NCT04826861 | University of Turku | N/A |
| Completed | Fermented Dairy Products and The Metabolic Syndrome NCT04755530 | Faidon Magkos | N/A |
| Completed | Anti-inflammatory Effect and Associated Mechanisms of Mango Consumption NCT04726293 | Clinical Nutrition Research Center, Illinois Institute of Technology | N/A |
| Completed | Adaptive Nutrition and Exercise Weight Loss (A-NEW) Study NCT04499950 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Phase 2 |
| Completed | Problematic Decision-Making and Adolescent Weight Loss NCT04848532 | Drexel University | N/A |
| Completed | Attitudes Toward Food During a Weight Loss Intervention NCT04586647 | Noom Inc. | N/A |
| Completed | The Effectiveness and Safety of HIIT in Overweight Male Subjects NCT05000437 | Indonesia University | N/A |
| Completed | Education to Decrease in Sodium Intake Evaluated With 24 Hour Urinary Sodium Excretion (RCT) NCT04894344 | Universidad Autonoma de Baja California | N/A |
| Completed | Electrical Vestibular Nerve Stimulation (VeNS) Compared to Sham Control as a Means of Reducing Excess Body Wei NCT04110717 | Neurovalens Ltd. | N/A |
| Active Not Recruiting | The Effects of Long-term Consumption of Full-fat Dairy Products on Satiety, Body Weight and Glycemic Control NCT04399460 | University of Toronto | N/A |
| Completed | Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IBI362 in Overweight or Obesity S NCT04440345 | Innovent Biologics (Suzhou) Co. Ltd. | Phase 1 / Phase 2 |
| Enrolling By Invitation | Antibiotic Prophylaxis in High-Risk Arthroplasty Patients NCT04297592 | Mayo Clinic | Phase 4 |
| Completed | A Proof of Concept Trial in Overweight and Obese Patients, Investigating Effect of EMP16-02 on Body Weight (Pr NCT04521751 | Empros Pharma AB | Phase 1 / Phase 2 |
| Withdrawn | A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Obesity NCT04100616 | ProgenaBiome | — |
| Recruiting | Promote Weight Loss in Obese Peripheral Artery Disease (PAD) Patients to Prevent Mobility Loss NCT04228978 | Northwestern University | N/A |
| Active Not Recruiting | Pulses Consumption and Its Role in Managing Systemic Inflammation, Insulin Sensitivity and Gut Microbiome in H NCT04267705 | Clinical Nutrition Research Center, Illinois Institute of Technology | N/A |
| Withdrawn | Long-term Consumption of Resistant Starch Type-4 (RS4) NCT04277741 | Kansas State University | N/A |
| Unknown | Modified Atkins Diet for Overweight and Obesity NCT04207879 | Hebei Medical University Third Hospital | — |
| Completed | Intermittent Fasting in Hypertriglyceridemic Overweight or Obese Subjects NCT04143971 | Shahid Beheshti University | N/A |
| Unknown | Impact of Time-Restricted Eating on Metabolic Homeostasis, Inflammation and Oxidative Stress in Metabolic Synd NCT04328233 | Nicolaus Copernicus University | N/A |
| Active Not Recruiting | Berries, Inflammation, and Gut Microbiome NCT04100200 | Clinical Nutrition Research Center, Illinois Institute of Technology | N/A |
| Completed | Treatment Efforts Addressing Child Weight Management by Unifying Patients, Parents & Providers NCT03843424 | Washington University School of Medicine | N/A |
| Active Not Recruiting | Hepatic Energy Fluxes in NASH and NAS Patients NCT03997422 | University of Minnesota | N/A |
| Terminated | Juice Plus Inflammaging and Cardiovascular Disease Prevention Study NCT04003935 | Green Beat | — |
| Terminated | A Study of FT 4101 in Overweight/Obese Participants With Non-alcoholic Steatohepatitis NCT04004325 | Forma Therapeutics, Inc. | Phase 1 / Phase 2 |
| Completed | Precision Nutrition Strategies for Improving the Quality of Life of Pre-senior and Senior Populations NCT04786925 | Clinica Universidad de Navarra, Universidad de Navarra | N/A |
| Completed | Examination of Circumferential Reduction NCT04451824 | Contour Research | N/A |
| Completed | A Research Study of NNC0165-1562 and Semaglutide in People Who Are Overweight or Obese NCT03574584 | Novo Nordisk A/S | Phase 1 |
| Completed | STEP 1: Research Study Investigating How Well Semaglutide Works in People Suffering From Overweight or Obesity NCT03548935 | Novo Nordisk A/S | Phase 3 |
| Completed | The Relationship Between Exercise Frequency, Intensity, and Restoration of Cardiometabolic Health NCT03376685 | University of Guelph | N/A |
| Completed | Efficacy of a Nutritive Bar, in Reduction of Weight, Body Fat and Control of Appetite NCT05104151 | CES University | N/A |
| Unknown | Capsaicin Effect on Cytokines Profile in Dyslipidemia NCT02823912 | University of Guadalajara | Phase 2 / Phase 3 |
| Recruiting | Community Park-Based Programs for Health Promotion: The Fit2Lead Prospective Cohort Study NCT06596265 | Duke University | — |
| Completed | Diet and Well-being of Young Danish Children NCT02170428 | University of Copenhagen | — |