NCT06762600

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HRS-4729 Injection in Healthy Subjects

A Randomized, Double-Blind, Dose-Escalation, Placebo-Controlled Phase I Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Subcutaneous Injections of HRS-4729 Injection in Healthy Subjects

• Status: Recruiting
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 103 (estimated)
• Sponsor: Fujian Shengdi Pharmaceutical Co., Ltd. · Industry
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

The study is being conducted to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of HRS-4729 injection in healthy subjects.

Conditions

• Overweight or Obesity

Interventions

Type	Name	Description
DRUG	HRS-4729 injection	HRS-4729 injection
DRUG	HRS-4729 injection placebo	HRS-4729 injection placebo
DRUG	HRS9531 injection	HRS9531 injection
DRUG	HRS9531 injection placebo	HRS9531 injection placebo
DRUG	Acetaminophen	Acetaminophen

Timeline

• Start date: 2025-01-16
• Primary completion: 2025-12-01
• Completion: 2025-12-01
• First posted: 2025-01-07
• Last updated: 2025-04-30

Locations

1 site across 1 country: China