NCT06426693

Craving Network Neurofeedback

Connectome-based Neurofeedback of the Craving Network to Reduce Food Cue Reactivity

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Yale University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

This project tests whether individuals with overweight or obesity and high craving can learn to change their brain response to food cues using neurofeedback, to impact their craving and eating behavior.

Detailed description

Aim 1 of this study is to test whether neurofeedback from the craving network is associated with reduced craving network strength. Aim 2 of this study is to test whether neurofeedback from the craving network is associated with reduced food craving and changes in eating behavior. Aim 3 of this study is to test whether neurofeedback from the craving network is associated with changes in resting state functional connectivity.

Conditions

• Overweight or Obesity

Interventions

Type	Name	Description
DEVICE	Experimental feedback	Participants provided with feedback of target brain activation patterns (e.g., thermometer) and will be instructed to try to change the feedback (e.g., decrease the thermometer).
DEVICE	Control feedback	Participants provided with control (sham, yoked to another participant) feedback (e.g., thermometer) and will be instructed to try to change the feedback (e.g., decrease the thermometer).

Timeline

• Start date: 2024-11-27
• Primary completion: 2027-03-31
• Completion: 2027-03-31
• First posted: 2024-05-23
• Last updated: 2025-12-03

Locations

1 site across 1 country: United States