NCT05957224

Differences in Postprandial Glucose Changes

An Intervention Comparing Changes in the Plasma Glucose Profile Over a Three-hour Timespan in Persons With T2DM Following Caribbean Shake vs Glucerna Intake: A Double Blinded, Cross-over Design

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 25 (estimated)
• Sponsor: The University of The West Indies · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Following a meal, in nondiabetic individuals, blood glucose rises to peak at 1hr and returns to baseline in 2 - 3 hours. In T2DM, this peak is higher and prolonged. Meal plans for persons with T2DM should comprise evenly spaced, complex carbohydrate portions in order to avoid post-prandial glucose spikes. Researchers have developed an expanded line of Caribbean-flavoured, low-calorie meal-replacement shakes which have been formulated to match the macronutrient and caloric content of a commercially available brand. In this trial investigators aim to (1) examine the change in glucose levels post intake of Caribbean vs the commercially available brand and (2) to conduct a comparative sensory analysis of the two shakes.

Conditions

• Diabetes Mellitus, Type II
• Overweight or Obesity

Interventions

Type	Name	Description
OTHER	Shake 1 then Shake 2	Oral administration of Caribbean low-calorie meal-replacement shake then commercial low-calorie meal-replacement shake
OTHER	Shake 2 then Shake 1	Oral administration of commercial low-calorie meal-replacement shake then Caribbean low-calorie meal-replacement shake

Timeline

• Start date: 2023-11-15
• Primary completion: 2024-05-15
• Completion: 2024-11-15
• First posted: 2023-07-24
• Last updated: 2023-07-24