| Not Yet Recruiting | Low-cost Screening and Image-guided Photodynamic Therapy (PDT) of Premalignant and Malignant Oral Lesions NCT06876038 | University of Massachusetts, Boston | Phase 2 |
| Not Yet Recruiting | Role of Subgingival Instrumentation in Oral Lichen Planus NCT07381595 | Postgraduate Institute of Dental Sciences Rohtak | N/A |
| Recruiting | Effect of Topical Bromelain Versus Topical Corticosteroids in the Management of Oral Lichen Planus NCT06981767 | Cairo University | Phase 2 |
| Not Yet Recruiting | Effectiveness of a Sodium Hyaluronate 0.01% and Sh-Oligopeptide-85 SP Mouthwash for the Treatment of Symptomat NCT07280442 | Universidad Complutense de Madrid | Phase 4 |
| Not Yet Recruiting | Efficacy of Coconut Gel Compared to Corticosteroid Gel in the Management of Oral Lichen Planus NCT07100145 | Ain Shams University | Phase 4 |
| Not Yet Recruiting | Cardiovascular and Prothrombotic Risk in Patients With Oral Lichen Planus. NCT07151014 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Not Yet Recruiting | Evaluation of Artificial Intelligence in Diagnosis and Risk Assessment of Oral Potentially Malignant Disorders NCT07318922 | Ain Shams University | — |
| Recruiting | Photobiomodulation, Er:YAG Laser, and Clobetasol in the Treatment of Oral Lichen Planus. NCT07278999 | Medical University of Silesia | N/A |
| Recruiting | Evaluation of Efficacy and Safety of add-on Tofacitinib in Patients With Oral Lichen Planus NCT07131813 | All India Institute of Medical Sciences, Bhubaneswar | Phase 4 |
| Recruiting | The Therapeutic Effect of Curcumin in Nanogels Compared to 0.1% FAO in the Management of Oral Lichen Planus NCT06932848 | Chulalongkorn University | N/A |
| Withdrawn | Systemic Absorption of Dexamethasone Oral Rinse in Patients With Oral Lichen Planus NCT06428630 | Tufts University | EARLY_Phase 1 |
| Not Yet Recruiting | Periodontal Initial Treatment Combined With Glucocorticoid Therapy for Erosive Oral Lichen Planus NCT06498180 | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University | N/A |
| Completed | Unveiling the Protein Expression Patterns in Oral Lichen Planus and Leukoplakia Through Comparative Salivary P NCT07416318 | Kocaeli University | — |
| Enrolling By Invitation | Hypnotherapy for Oral Lichen Planus. Patients with Clinically and Histologically Confirmed Oral Lichen Planus NCT06697574 | Tel-Aviv Sourasky Medical Center | N/A |
| Enrolling By Invitation | Thyme Honey for Management of Oral Lichen Planus NCT06810752 | British University In Egypt | Phase 1 / Phase 2 |
| Recruiting | Mucoadhesive Modified-Release Formulations for the Topical Treatment of Symptomatic Oral Lichen Planus NCT07100613 | University of Palermo | Phase 2 |
| Active Not Recruiting | Evaluating LP-10 in Subjects With OLP NCT06233591 | Lipella Pharmaceuticals, Inc. | Phase 2 |
| Unknown | Topical Erythropoietin Hydrogel in Management of Oral Lichen Planus NCT06135259 | Ain Shams University | Phase 3 |
| Completed | Artificial Intelligence Based Program to Classify Oral Cavity Findings Based on Clinical Image Analysis NCT06325514 | Cairo University | — |
| Active Not Recruiting | Efficacy and Safety of Baricitinib in Oral Lichen Planus: a Proof-of-Concept Study NCT06158113 | University of North Carolina, Chapel Hill | Phase 2 |
| Recruiting | SYsteMatical Trained learnIng aLgorithms for Oral carcInogenesiS Interpretation by Optical Coherence Tomograph NCT06321003 | University of Palermo | — |
| Recruiting | Rate of Malignant Transformation and Clinical Characteristics Among an Oral Lichen Planus Cohort: a Retrospect NCT06934863 | Catholic University of the Sacred Heart | — |
| Completed | Efficacy and Safety of add-on Apremilast Versus add-on Methotrexate in Patients With Oral Lichen Planus NCT06260904 | All India Institute of Medical Sciences, Bhubaneswar | Phase 4 |
| Active Not Recruiting | Melatonin Epigenetic Potential in Preventing Malignant Transformation of Oral Lichen Planus NCT06533033 | Hams Hamed Abdelrahman | N/A |
| Completed | Salivary and Serum Leptin Levels in Oral Lichen Planus Patients: A Case-control Study. NCT06078579 | Cairo University | — |
| Completed | Metagenomic Analysis of the Oral Microbiome in Patients With Oral Lichen Planus: A Pilot Study in the Turkish NCT07137156 | Kahramanmaras Sutcu Imam University | — |
| Completed | Association Between Oral Lichen Planus and Thyroid Disease NCT06550154 | University of Barcelona | — |
| Completed | Impact of Fluocinonide 0,05% in Oral Lichen Planus NCT06135805 | University of Catania | N/A |
| Unknown | Efficacy of Ginger Muco-bioadhesive Gel in Management of Oral Lichen Planus With Immunohistochemical Analysis NCT05882864 | Ain Shams University | Phase 4 |
| Completed | Vitamin D Deficiency As a Risk Factor for the Development and Malignant Transformation of Oral Lichen Planus NCT06033105 | Fayoum University | — |
| Completed | The Role of Vitamin D in Amelioration of Oral Lichen Planus and Its Effect on Salivary IFN-γ Level NCT06204796 | Fayoum University | Phase 4 |
| Recruiting | Treatment of Oral Lichen Planus With Paeoniflorin and Photodynamic Therapy NCT05973097 | Peking University Third Hospital | N/A |
| Unknown | Identification of Oral Lesions Through an Autofluorescence System NCT05942794 | Federico II University | N/A |
| Completed | A Comparison of Photodynamic Therapy and Topical Clobetasol in Treatment of Oral Lichen Planus: a Split-Mouth NCT06752343 | Wroclaw Medical University | Phase 2 |
| Completed | Assessment of the Efficacy of Topical Curcumin in Treatment of Oral Lichen Planus NCT06605911 | Shaymaa Hussein Rafat Kotb | Phase 3 |
| Completed | Efficacy of Topical Glucosamine Versus Corticosteroid in Oral Lichen Planus NCT07114016 | Future University in Egypt | Phase 4 |
| Unknown | Efficacy of Probiotic Capsules With Topical Clobetasol Propionate in OLP Treatment NCT06119672 | October 6 University | Phase 3 |
| Completed | Different Treatment Modalities for Oral Lichen Plan NCT06681090 | Al-Azhar University | Phase 1 |
| Active Not Recruiting | Topical Sulfasalazine and Oral Lichen Planus NCT06060301 | Cairo University | Phase 3 |
| Completed | Dual-light Antibacterial Photodynamic Therapy as an Adjunctive Treatment to Corticosteroid Treatment in OLP NCT05401201 | Koite Health Oy | N/A |
| Completed | Evaluation of Efficacy of Neem (Azadirachta Indica) Versus Triamcinolone Acetonide in the Treatment of Oral Li NCT07141446 | Goa Dental College | Phase 1 / Phase 2 |
| Completed | the Oncogenic Potential of Salivary miRNA-93 and miRNA-412-3P in Oral Lichen Planus Patients NCT05400057 | Moataz Mahmoud | — |
| Completed | Discomfort Following Oral Biopsy Comparing Laser and Punch Biopsy NCT07414797 | Catholic University of the Sacred Heart | N/A |
| Completed | Oral Zinc Supplement as Adjunctive Therapy for Erosive Oral Lichen Planus NCT06042010 | Hams Hamed Abdelrahman | N/A |
| Completed | Oral Lichen Planus and Systemical Oncological Comorbidities NCT06449248 | Catholic University of the Sacred Heart | — |
| Completed | Relationship Between Oral Lichen Planus and Autoimmune Thyroid Diseases NCT05403216 | The Dental Hospital of Zhejiang University School of Medicine | — |
| Completed | Diagnostic Accuracy of lncRNA DQ786243 and miRNA146a in Saliva of Oral Potentially Malignant Lesions NCT05730855 | Fayoum University | — |
| Completed | Evaluating Treatment Efficacy in Oral Lichen Planus: The Role of Salivary Biomarkers NCT06332365 | Pia Lopez Jornet | N/A |
| Completed | Impact of PDT and Topical Corticosteroids on Taste Perception in Patients With OLP NCT07536737 | Medical University of Bialystok | N/A |
| Completed | Micronutrients in Management of Symptomatic Oral Lichen Planus NCT04765267 | Cairo University | N/A |
| Unknown | Diagnostic Accuracy of Salivary Gamma-synuclein in Oral Malignant and Premalignant Lesions NCT04732741 | Cairo University | — |
| Completed | Prevalence of Lichen Planus NCT06787872 | University of Ljubljana | — |
| Completed | Dexamethasone Solution and Dexamethasone in Mucolox™ NCT04540133 | University of California, San Francisco | Phase 2 |
| Unknown | The Regulatory Role of Immune Response in Oral Lichen Planus NCT05997173 | Peking University Third Hospital | — |
| Completed | Prolactin Hormone in Oral Lichen Planus NCT04785703 | October University for Modern Sciences and Arts | — |
| Active Not Recruiting | Efficacy of Topical Treatment With Clobetasol in Symptomatic Oral Lichen Planus. NCT04364555 | Malmö University | Phase 2 / Phase 3 |
| Completed | Impact of Topical Clobetasol on Gingival Crevicular Fluid miRNAs in Subjects Affected by Oral Lichen Planus NCT05818618 | University of Catania | N/A |
| Completed | Evaluation of the Effectiveness of Photodynamic Therapy in the Treatment of Lesions of the Lichen Planus Type NCT04991012 | Wroclaw Medical University | Phase 2 |
| Terminated | Intra and Extra Oral Inspection of Oral Mucosa NCT04079491 | Dalarna County Council, Sweden | — |
| Unknown | Effect of Oral Zinc Supplementation as an Adjuvant to Topical Corticosteroid in Oral Lichen Planus Patients NCT04278599 | Postgraduate Institute of Dental Sciences Rohtak | Phase 4 |
| Completed | Association of Oral Lichen Planus and Thyroid Disease NCT04523077 | University of Zagreb | — |
| Unknown | Matrix Metalloproteinases Neutralizing Agents in Oral Lichen Planus NCT04336488 | Jaylane kadry Ghonima | EARLY_Phase 1 |
| Unknown | The Efficacy of Topical Sesame Oil Versus Topical Triamcinolone on Oral Lichen Planus and Salivary Level of Ox NCT03738176 | Mona Taha Mohammed MD | EARLY_Phase 1 |
| Recruiting | Prediction of Malignant Transformation of Oral Leukoplakia Using a MAGE-A-based Immunoscore NCT03975322 | University of Erlangen-Nürnberg Medical School | — |
| Withdrawn | Apremilast - Oral Lichen Planus Trial NCT03836885 | Sunnybrook Health Sciences Centre | Phase 2 |
| Unknown | Clinical and Biochemical Assessment of the Effect of Topical Use of Coenzyme Q10 Versus Topical Corticosteroid NCT04091698 | Cairo University | Phase 1 |
| Completed | Diagnostic Accuracy of Salivary DNA Integrity Index in Oral Malignant and Premalignant Lesions NCT03682562 | Cairo University | — |
| Completed | Evaluation of Topical Pomegranate Extracts in Management of Oral Lichen Planus (A Randomized Clinical Trial) NCT04193748 | Cairo University | Phase 4 |
| Completed | Evaluation of Mucoadhesive Tacrolimus Patch on Caspase-3 Inducing Apoptosis in Oral Lichen Planus NCT05139667 | Ain Shams University | Phase 4 |
| Unknown | The Effect of Topical Curcumin Versus Topical Corticosteroid on Management of Oral Lichen Planus Patients NCT03877679 | Cairo University | Phase 1 |
| Completed | Evaluation of Salivary Level of miR-155 and IL-10 in Oral Lichen Planus Patients Before and After Treatment Wi NCT03871114 | Cairo University | — |
| Completed | Malondialdehyde and Nitrous Oxide as Salivary Biomarkers for Different Oral Lesions NCT04267419 | Beni-Suef University | — |
| Unknown | Evaluation of Topical Chamomile Versus Topical Triamcinolone Acetonide in Management of Oral Lichen Planus NCT03793634 | Cairo University | Phase 1 |
| Completed | Oral Epithelial Dysplasia Informational Needs Questionnaire NCT04153266 | University College, London | — |
| Completed | Intra-oral Treatment of OLP With Rivelin®-CLO Patches NCT03592342 | Dermtreat | Phase 2 |
| Completed | Oral Lichen Planus Treatment NCT05127083 | Universidad de Murcia | N/A |
| Completed | Use of Topical NSAID to Reduce Pain in Oral Lichen Planus and Oral Lichenoid Lesions. NCT03509675 | University of Washington | Phase 2 / Phase 3 |
| Unknown | Efficacy of Green Tea Buccal Tablets in Oral Lichen Planus NCT03415165 | Cairo University | EARLY_Phase 1 |
| Completed | Effect of Bifidobacterium Animalis Subsp. Lactis HN019 on Oral Lichen Planus NCT03386643 | University of Sao Paulo | Phase 2 |
| Completed | The Clinical and Biological Effects Of The Use Of Probiotic VSL#3 In Patients With Oral Lichen Planus NCT03052179 | University College, London | N/A |
| Unknown | Treatment Modalities of Oral Lichen Planus NCT03237533 | University of Faisalabad | EARLY_Phase 1 |
| Completed | Management of Pain in Oral Lichen Planus NCT03572959 | Sherine Adel Nasry | Phase 4 |
| Completed | Molecular & Cellular Characterisation of Oral Lichen Planus NCT04289233 | University of Birmingham | — |
| Unknown | Topical Betamethasone and Clobetasol in Orabase in Oral Lichen Planus NCT03026478 | Garlapati Komali | Phase 2 |
| Completed | Effect of Adjunctive Systemic Vitamin E on Clinical Parameters and Salivary Total Antioxidant Capacity in Symp NCT04126720 | Cairo University | Phase 1 |
| Completed | Expression of miRNa-138 and Cyclin D1 in Oral Mucosa of Patients With Oral Lichen Planus NCT02834520 | Cairo University | — |
| Completed | Glucosamine as a Novel Adjunctive Therapy in Oral Lichen Planus NCT02858297 | Ain Shams University | Phase 4 |
| Completed | Comparison or Rose Bengal and Toluidine Blue Staining for Lesion Detection Efficacy NCT03031899 | The Oxford Dental College, Hospital and Research Center, Bangalore, India | — |
| Unknown | Based on Metabonomics Dryness Pathogen Type of OLP: a Dynamic Study NCT02332486 | Heilongjiang University of Chinese Medicine | N/A |
| Completed | The Association Between Diabetes Mellitus, Oral Lichen Planus and Insulin-like Growth Factors 1 and 2 (IGF1 an NCT03257228 | University of Zagreb | — |
| Completed | Comparison of Tacrolimus 0.1% and Clobetasol 0.05% in the Management of Symptomatic Oral Lichen Planus NCT02744378 | University of Peradeniya | Phase 2 |
| Completed | Chamaemelum Nobile 2% Versus Placebo Topic Gel to Treat Oral Lichen Planus NCT02421770 | Universidad de Murcia | Phase 3 |
| Completed | Comparison of Triamcinolone Acetonide Mucoadhesive Film and Licorice Mucoadhesive Film Effect on Lichen Planus NCT02453503 | Isfahan University of Medical Sciences | Phase 2 |
| Completed | Evaluation of Green Tea as Antioxidant Agent in Management of Oral Lichen Planus NCT02329600 | Cairo University | Phase 3 |
| Completed | The Efficacy of Omega-3 in Treatment of Atrophic/Erosive Lichen Planus NCT02106468 | October 6 University | Phase 2 |
| Completed | A Clinical Trial to Study the Effects of Two Drugs, Lycopene and Prednisolone in Patients With Oral Lichen Pla NCT02587117 | B.P. Koirala Institute of Health Sciences | Phase 4 |
| Completed | The Use of Probiotics in Patients With Symptomatic Oral Lichen Planus NCT01743690 | University of Copenhagen | N/A |
| Completed | Acquired Chronic Erosive Gingivitis: Clinical Relevance of Papillary Gingival Biopsy NCT04293718 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | Topical "Non-Aromatic Very Rich in Steranes" (NAVS) Naphthalan for the Treatment of Oral Mucosal Diseases NCT02920658 | Ivan Alajbeg | Phase 2 |
| Completed | Clinical and Immunohistochemical Effect of Topical Pimecrolimus in Treatment of Oral Lichen Planus NCT02443311 | Ain Shams University | Phase 4 |
| Unknown | The Efficacy of Topical Minocycline in Managing Symptomatic Oral Lichen Planus NCT01083420 | Sheba Medical Center | Phase 3 |
| Completed | Molecular Mechanisms of the Development of Precancerous and Cancerous Lesions of the Oral Cavity NCT03026361 | University of Zagreb | — |
| Unknown | A Randomized Clinical Trial of the Effect of Pimecrolimus Cream 1% Compared With Topical Corticosteroid in Tre NCT01524744 | Mashhad University of Medical Sciences | Phase 2 |
| Unknown | Free Soft Tissue Graft in Treatment of Oral Lichen Planus NCT00737854 | Qazvin University Of Medical Sciences | Phase 1 |
| Terminated | Efficacy of Topical Rapamycin to Treat Chronic Erosive Oral Lichen NCT01061853 | University Hospital, Tours | Phase 3 |
| Completed | A Clinical Study of Curcuminoids in the Treatment of Oral Lichen Planus NCT00525421 | Nita Chainani Wu | Phase 2 |
| Completed | Study of Metronidazole and Doxycycline to Treat Oral Lichen Planus and to Compare Their Efficacy With Each Oth NCT00484250 | Mashhad University of Medical Sciences | Phase 2 |
| Completed | Pimecrolimus Cream for Oral Lichen Planus NCT00297037 | University of Utah | Phase 2 |
| Completed | Dexamethasone to Treat Oral Lichen Planus NCT00111072 | National Institute of Dental and Craniofacial Research (NIDCR) | Phase 2 |
| Terminated | Tacrolimus Ointment in Oral Lichen Planus NCT01544842 | University of Oulu | N/A |
| Completed | Impact of Continuous Defocused CO2 Laser Vaporisation on the Histological Malignant Transformation of Erosive NCT02154607 | Technical University of Munich | N/A |
| Terminated | A Randomized, Placebo-controlled, Double-blind Clinical Trial of Curcuminoids in Oral Lichen Planus NCT00226174 | University of California, San Francisco | Phase 2 |