NCT04523077

Association of Oral Lichen Planus and Thyroid Disease

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 50 (actual)
• Sponsor: University of Zagreb · Academic / Other
• Sex: Female
• Age: 35 Years – 70 Years
• Healthy volunteers: Accepted

Summary

Thyroid disease is a common endocrine disorder. Oral lichen planus (OLP) is a chronic autoimmune disease that occurs on the oral mucosa in 1-2% of the general population.The purpose of this study was to determine whether there is an association between thyroid disease and oral planus lichen in the population of our patients. In the last few years, a couple of studies have been published in the world literature that have studied the possible association of these diagnoses in different populations. Most of the results showed a higher prevalence of thyroid disease in the population of lichen patients, compared with patients without lichen, although some results are contradictory. Some authors believe that the onset of OLP precedes thyroid dysfunction. In the population of Croatian patients with lichen, no research has been done to study the possible connection between these two diseases. The obtained results could help clarify whether there is a connection between these two diagnoses in the population of our lichen patients and enable earlier detection of patients with thyroid hypofunction.

Conditions

• Oral Lichen Planus
• Thyroid Diseases

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	determination of thyroid hormones and antibodies	TSH, fT3, fT4, anti-TPO and anti-Tg were determined from blood sample

Timeline

• Start date: 2020-01-01
• Primary completion: 2020-04-30
• Completion: 2020-04-30
• First posted: 2020-08-21
• Last updated: 2020-08-25

Locations

1 site across 1 country: Croatia