NCT06135805

Impact of Fluocinonide 0,05% in Oral Lichen Planus

Impact of the Efficacy of Fluocinonide 0.05% Oral Gel in the Treatment of Oral Lichen Planus

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 47 (actual)
• Sponsor: University of Catania · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

A double-blind placebo-controlled trial is conducted in order to evaluate the efficacy of Fluocinonide 0,05% and determinate the statistical significance of the outcome variables. Oral cavity lichen is a chronic inflammatory condition affecting the mucosa of the oral cavity , which significantly reduces the quality of life of affected individuals.

Detailed description

A double-blind placebo-controlled study was conducted to evaluate the clinical efficacy of Fluocinonide 0.05% oral gel and determine the statistical significance of outcome variables. 20 patients with Oral Lichen Planus were divided by a randomization system, into two groups: case group treated with Fluocinonide 0.05% oral gel and applied to oral lesions 2 times a day for 1 month and a placebo group as a control group; with 2 months of follow-up.

Conditions

• Oral Lichen Planus

Interventions

Type	Name	Description
DRUG	Fluocinonide 0,05% oral gel	Application of Fluocinonide oral gel on oral syntomatic lesions
DRUG	Placebo	Application of placebo oral gel on oral lesions

Timeline

• Start date: 2023-08-20
• Primary completion: 2024-02-28
• Completion: 2024-02-28
• First posted: 2023-11-18
• Last updated: 2024-09-19

Locations

1 site across 1 country: Italy