NCT03738176

The Efficacy of Topical Sesame Oil Versus Topical Triamcinolone on Oral Lichen Planus and Salivary Level of Oxidative Stress Biomarker [MDA]

The Efficacy of Topical Sesame Oil in Orabase Versus Topical Triamcinolone in Orabase on Oral Lichen Planus and Salivary Level of Oxidative Stress Biomarker, Malondialdehyde [MDA] : Randomized Clinical Trial (RCT)

• Status: Unknown
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Mona Taha Mohammed MD · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

use seseme oil and corticosteroid topically for two groups

Detailed description

* The enrolled patients will be divided randomly into two groups. * Test group will receive topical sesame oil (3 times /day after eating) for a month. * Control group will receive topical corticosteroid (3 times /day after eating) for a month. * Assessment of the appearance score and severity of pain as well as the clinical parameter outcome will be done at baseline and at the end of two and four weeks and will be recorded in the patients' questionnaires \& by clinical sign score . MDA will be measured at the baseline \& at the end of four weeks after treatment.

Conditions

• Oral Lichen Planus

Interventions

Type	Name	Description
DRUG	Sesame Oil	Sesame oil(80 gm NaCMC-20 gmSesame oil)
DRUG	triamcinolone in orabase	triamcinolone 140 gm-Na CMC 50 gm

Timeline

• Start date: 2019-12-16
• Primary completion: 2020-11-16
• Completion: 2020-12-30
• First posted: 2018-11-13
• Last updated: 2019-08-02