| Recruiting | Trifluridine/Tipiracil + Oxaliplatin in Participants With Advanced or Metastatic Biliary Tract Cancer NCT07146646 | Case Comprehensive Cancer Center | Phase 2 |
| Not Yet Recruiting | Proteomic Analysis of Patients Undergoing Bariatric Surgery NCT06787807 | Universidade Federal de Pernambuco | N/A |
| Active Not Recruiting | Toripalimab Combined With Capecitabine as Postoperative Adjuvant Therapy for Patients With Resectable Advanced NCT06717464 | Tianjin Medical University Cancer Institute and Hospital | Phase 2 |
| Active Not Recruiting | Predicting Incidental Gallbladder Cancer NCT06531408 | University Hospital Plymouth NHS Trust | — |
| Enrolling By Invitation | Gem+Nab-P+LEN+TIS for Advanced Unresectable BTC (GALENT-BT) NCT06963060 | Wei Gong | Phase 2 |
| Not Yet Recruiting | Construction of Multicenter Retrospective Registry Cohort Database for Gallbladder Cancer NCT06276153 | RenJi Hospital | — |
| Recruiting | STALL vs Sole Local Wound Infiltration in Laparoscopic Cholecystectomy NCT06123117 | Helsinki University Central Hospital | N/A |
| Active Not Recruiting | UCAD for Diagnosing Benign or Malignant Gallbladder Diseases and Follow-up NCT06232538 | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | — |
| Unknown | Combination Therapy of HAIC, Surufatinib and Tislelizumab for Unresectable or Metastatic Biliary Tract Cancer NCT06134193 | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | Phase 2 |
| Active Not Recruiting | A Study of LSTA1 When Added to Standard of Care Versus Standard of Care Alone in Patients With Advanced Solid NCT05712356 | Lisata Therapeutics, Inc. | Phase 2 |
| Completed | Global Evaluation of Cholecystectomy Knowledge and Outcomes NCT06223061 | University of Edinburgh | — |
| Not Yet Recruiting | The Construction of Clinical Database and Multiomics Biobank Based on a Multicentral Prospective Cohort of Ben NCT05896956 | RenJi Hospital | — |
| Unknown | Robot-assisted vs Laparoscopic vs Open Radical Cholecystectomy for Gallbladder Cancer NCT06061744 | Hospital del Mar | — |
| Unknown | Envafolimab Combined With GEMOX in First-line Treatment of Advanced GBC NCT06013943 | Eastern Hepatobiliary Surgery Hospital | Phase 2 |
| Unknown | Deep Learning Radiogenomics For Individualized Therapy in Unresectable Gallbladder Cancer NCT05718115 | Post Graduate Institute of Medical Education and Research, Chandigarh | — |
| Recruiting | Combination of Gemcitabine, Albumin-paclitaxel , Sintilimab and Bevacizumab in Unresectable Gallbladder Cancer NCT05757336 | Lu Wang, MD, PhD | Phase 2 |
| Recruiting | Addition of Everolimus to Standard of Care in Carcinoma Gallbladder NCT05833815 | Banaras Hindu University | Phase 2 / Phase 3 |
| Completed | To Evaluate Efficacy and Safety of TT-00420 (Tinengotinib) as Monotherapy and Combination Therapy in Patients NCT05253053 | TransThera Sciences (Nanjing), Inc. | Phase 1 / Phase 2 |
| Completed | Artificial Intelligence-based Tumor Microenvironment Analysis for Prognosis Prediction in Gallbladder Cancer NCT07092397 | Samsung Medical Center | — |
| Unknown | Association Between Cell-free Nucleic Acid in Blood, Urine and Microbiome in Stool With Pancreatobiliary Cance NCT05596370 | Seoul National University Hospital | — |
| Recruiting | Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes NCT04907643 | Cedars-Sinai Medical Center | N/A |
| Unknown | A Prospective Study of UCAD for Diagnosing Benign or Malignant Biliary Obstruction and Follow-up NCT05237193 | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | — |
| Completed | Biomarker Discovery in Patients With Advanced Biliary Tract Cancer NCT04871321 | CHA University | — |
| Completed | Study of TT-00420 (Tinengotinib) Tablet as Monotherapy and Combination Therapy in Patients With Advanced Solid NCT04742959 | TransThera Sciences (Nanjing), Inc. | Phase 1 / Phase 2 |
| Completed | Poorly Differentiated Adenocarcinoma With Signet Ring Cells of the Gallbladder Producing a High Level of Alpha NCT05559229 | junya mita | — |
| Terminated | The PLATON Network NCT05489250 | Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest | — |
| Completed | PLATON - Platform for Analyzing Targetable Tumor Mutations (Pilot-study) NCT04484636 | Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest | N/A |
| Unknown | Hepatobiliary Tumors Tissue Samples Acquisition NCT04445532 | Peking Union Medical College Hospital | — |
| Terminated | Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors NCT04383210 | Elevation Oncology | Phase 2 |
| Completed | Behavioral Weight Loss Program for Cancer Survivors in Maryland NCT04534309 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | N/A |
| Terminated | Feasibility Study of Multi-Platform Profiling of Resected Biliary Tract Cancer NCT04561453 | University of Washington | — |
| Unknown | Adjuvant Immunotherapy Combined With Chemoradiation for Patients With High-risk reseCtable Extrahepatic chOlan NCT04333927 | Sun Yat-sen University | Phase 2 |
| Active Not Recruiting | Neoadjuvant Gemcitabine Plus Cisplatin With or Without Durvalumab in Resectable Biliary Tract Cancer NCT04308174 | Asan Medical Center | Phase 2 |
| Completed | Pembrolizumab in Biliary Tract Cancer NCT03260712 | European Organisation for Research and Treatment of Cancer - EORTC | Phase 2 |
| Recruiting | EULAT Eradicate GBC NCT06192719 | Centre Paul Strauss | — |
| Terminated | Gemcitabine Plus Cisplatin With or Without Bintrafusp Alfa (M7824) in Participants With 1L BTC NCT04066491 | EMD Serono Research & Development Institute, Inc. | Phase 2 / Phase 3 |
| Completed | M7824 Monotherapy in Locally Advanced or Metastatic Second Line (2L) Biliary Tract Cancer (Cholangiocarcinoma NCT03833661 | EMD Serono Research & Development Institute, Inc. | Phase 2 |
| Unknown | Comparing the Current Hydration Regimen for the ABC02 Chemotherapy Regimen Versus a Shorter Hydration NCT04362449 | Imperial College Healthcare NHS Trust | Phase 2 |
| Unknown | Three Dimension Laparoscopic Versus Open Surgery for Gallbladder Carcinoma NCT03491878 | Tongji Hospital | N/A |
| Recruiting | The Relationship Between Triceps Skinfold and Overall Survival of Pancreas, Bile Duct, Gallbladder Cancer NCT03637569 | Samsung Medical Center | — |
| Recruiting | NGS in Gallbladder Cancer and Response to Treatment NCT05404347 | Banaras Hindu University | — |
| Completed | Pembrolizumab, a Monoclonal Antibody Against PD-1, in Combination With Capecitabine and Oxaliplatin (CAPOX) in NCT03111732 | National Cancer Institute (NCI) | Phase 2 |
| Unknown | Observational Study on Patients With Hepatobiliary Tumors NCT04637048 | Gang Chen, MD | — |
| Completed | Chile Biliary Longitudinal Study NCT02692911 | National Cancer Institute (NCI) | — |
| Unknown | Molecularly Target Therapy With FORFIRINOX in Advanced or Recurrent Extrahepatic Cholangiocarcinoma and Gallbl NCT03768375 | Shanghai Jiao Tong University School of Medicine | Phase 2 |
| Completed | Programs To Support You During Chemotherapy NCT02489422 | Wake Forest University Health Sciences | N/A |
| Unknown | Chemothetapy FORFIRINOX in Advanced or Recurrent Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma NCT03772132 | Shanghai Jiao Tong University School of Medicine | Phase 2 |
| Unknown | Molecularly Target Therapy With GEMOX in Advanced or Recurrent Extrahepatic Cholangiocarcinoma and Gallbladder NCT02836847 | Shanghai Jiao Tong University School of Medicine | Phase 2 |
| Unknown | Two-in-one Covered and Uncovered Metal Stent NCT04337333 | Ajou University School of Medicine | N/A |
| Unknown | T Cell Mediated Adaptive Therapy for Her2-positive Neoplasms of Digestive System NCT02662348 | Yi Miao | Phase 1 |
| Unknown | A Study for Efficacy of Side-by-side Compared to Stent-in-stent Technique in the Endoscopic Management of Mali NCT02659852 | Yonsei University | N/A |
| Unknown | International Registry of Patients Treated With Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) NCT03210298 | Sabine Rhode | — |
| Completed | ABC-08: Phase Ib Trial of Acelarin in Combination With Cisplatin in Locally Advanced/ Metastatic Biliary Tract NCT02351765 | The Christie NHS Foundation Trust | Phase 1 |
| Active Not Recruiting | Copper Cu 64 Anti-CEA Monoclonal Antibody M5A PET in Diagnosing Patients With CEA Positive Cancer NCT02293954 | City of Hope Medical Center | N/A |
| Recruiting | Identification of New Biomarkers for Patients With Cholangiocarcinoma and Gallbladder Cancer NCT05184400 | Herlev and Gentofte Hospital | — |
| Completed | Alcohol Consumption and Gallbladder Cancer NCT02326948 | Cheju Halla General Hospital | — |
| Recruiting | The Effect in Wedge Resection and IVb/V Resection of the Liver for Gallbladder Cancer NCT02920554 | Saint Vincent's Hospital, Korea | N/A |
| Completed | Active Symptom Control Alone or With mFOLFOX Chemotherapy for Locally Advanced/ Metastatic Biliary Tract Cance NCT01926236 | The Christie NHS Foundation Trust | Phase 3 |
| Recruiting | Integrated Cancer Repository for Cancer Research NCT02012699 | University of Nebraska | — |
| Completed | Evaluation of the Effectiveness of Intraoperative Frozen Section on the Treatment of Suspected Gallbladder Can NCT06189664 | Imperial College London | — |
| Recruiting | Quebec Pancreas Cancer Study NCT04104230 | George Zogopoulos | — |
| Completed | Adjuvant Chemotherapy vs no Chemotherapy for Patients With GallBllader Carcinoma NCT02778308 | Govind Ballabh Pant Institute of Postgraduate Medical Education and Research | N/A |
| Completed | Gemcitabine, Oxaliplatin and Panitumumab in Kras/B-raf Wild-Type Biliary Track and Gallbladder Cancer NCT01308840 | University of Rochester | Phase 2 |
| Unknown | A Randomized, Open, Prospective Clinical Research of Fluorouracil Implant to Improve Surgical Gallbladder Canc NCT01317069 | Simcere Pharmaceutical Co., Ltd | Phase 2 |
| Completed | Gemcitabine Hydrochloride, Oxaliplatin, and Erlotinib Hydrochloride in Treating Patients With Advanced Biliary NCT00987766 | Vanderbilt-Ingram Cancer Center | Phase 1 |
| Terminated | Palonosetron Hydrochloride in Preventing Nausea and Vomiting Caused by Radiation Therapy in Patients With Prim NCT00903396 | Alliance for Clinical Trials in Oncology | Phase 2 |
| Terminated | A Study of Combination of Gemcitabine, Oxaliplatin (GEMOX)-Sorafenib in Patients With Advanced Biliary Tract C NCT00955721 | University of Miami | Phase 1 / Phase 2 |
| Completed | Gemcitabine and Cisplatin Plus Sorafenib in Patients With Advanced Biliary Tract Carcinomas Naive to Systemic NCT00919061 | Memorial Sloan Kettering Cancer Center | Phase 2 |
| Completed | Gemcitabine Hydrochloride and Oxaliplatin or Observation in Treating Patients With Biliary Tract Cancer That H NCT01313377 | UNICANCER | Phase 3 |
| Completed | Quality of Life in Patients Undergoing Radiation Therapy for Primary Lung Cancer, Head and Neck Cancer, or Gas NCT00836992 | Mayo Clinic | — |
| Completed | S0809: Capecitabine, Gemcitabine, and RT in Patients w/Cholangiocarcinoma of the Gallbladder or Bile Duct NCT00789958 | SWOG Cancer Research Network | Phase 2 |
| Completed | Radiation Stent Versus Self-expanding Metallic Stents (SEMS) for Palliative Treatment of Malignant Biliary Str NCT01320241 | Southeast University, China | Phase 2 |
| Terminated | Gemcitabine With/Out Capecitabine in Locally Advanced, Unresectable, or Metastatic Biliary Cancer NCT00658593 | NCIC Clinical Trials Group | Phase 3 |
| Completed | Vandetanib Gemcitabine Or Placebo Plus Gemcitabine Or Vandetanib Monotherapy In Advanced Biliary Tract Cancer NCT00753675 | Genzyme, a Sanofi Company | Phase 2 |
| Completed | Irinotecan, Fluorouracil, and Leucovorin in Treating Patients With Advanced Gastrointestinal Cancer NCT00654160 | Mayo Clinic | Phase 1 |
| Completed | Comprehensive Electronic Cancer Support System for the Treatment of Cancer Related Symptoms NCT01640522 | University of Pittsburgh | N/A |
| Terminated | Psychological and Emotional Impact in Patients Undergoing Treatment For Metastatic Cancer Either in a Clinical NCT00896467 | Centre Oscar Lambret | — |
| Terminated | Gemcitabine, Oxaliplatin, Tarceva &/or Cisplatin in HCC & Biliary Tree Cancers NCT00832637 | New Mexico Cancer Research Alliance | Phase 2 |
| Completed | Biliary Stenting With or Without Photodynamic Therapy in Treating Patients With Locally Advanced, Recurrent, o NCT00513539 | University College, London | Phase 3 |
| Completed | Safety and Immune Response to a Multi-component Immune Based Therapy (MKC1106-PP) for Patients With Advanced C NCT00423254 | Mannkind Corporation | Phase 1 |
| Terminated | Storage of Bile From Routine Procedures to Study Risk Factors NCT00414843 | Indiana University School of Medicine | — |
| Withdrawn | Study to Test the Benefit and Safety of GM-CT-01 in Combination With 5-FU to Treat Bile Duct and Gall Bladder NCT00386516 | Galectin Therapeutics Inc. | Phase 2 |
| Completed | Avastin and Tarceva for Upper Gastrointestinal Cancers NCT00350753 | Rigshospitalet, Denmark | Phase 2 |
| Completed | Capecitabine or Observation After Surgery in Treating Patients With Biliary Tract Cancer NCT00363584 | University Hospital Southampton NHS Foundation Trust | Phase 3 |
| Terminated | Escitalopram in Treating Depression in Patients With Advanced Lung or Gastrointestinal Cancer NCT00387348 | Massachusetts General Hospital | Phase 3 |
| Completed | Palliative Biliary Stenting on the Quality of Life of Patients With Unresectable Carcinoma Gallbladder With Hi NCT00391183 | All India Institute of Medical Sciences | Phase 2 / Phase 3 |
| Completed | Biliary Metal Stent Study: Metal Stents for Management of Distal Malignant Biliary Obstruction NCT00280709 | University Hospital, Linkoeping | Phase 4 |
| Completed | Fluorouracil, Cisplatin, and Radiation Therapy or Gemcitabine and Oxaliplatin in Treating Patients With Nonmet NCT00304135 | Federation Francophone de Cancerologie Digestive | Phase 2 / Phase 3 |
| Completed | Gemcitabine With or Without Cisplatin in Treating Patients With Unresectable Locally Advanced or Metastatic Ch NCT00262769 | University College, London | Phase 3 |
| Completed | Quality Of Life in Patients With Malignant Biliary Obstruction NCT00579865 | Memorial Sloan Kettering Cancer Center | — |
| Completed | Capecitabine, Epirubicin, and Carboplatin in Treating Patients With Progressive, Unresectable, or Metastatic C NCT00486356 | University of Nebraska | Phase 1 |
| Completed | Oxaliplatin, Gemcitabine, Erlotinib, and Radiation Therapy in Treating Patients With Unresectable and/or Metas NCT00266097 | UNC Lineberger Comprehensive Cancer Center | Phase 1 |
| Completed | Gemcitabine Plus Pemetrexed Disodium in Treating Patients With Unresectable or Metastatic Biliary Tract or Gal NCT00059865 | Alliance for Clinical Trials in Oncology | Phase 1 / Phase 2 |
| Completed | Endoscopic Versus Percutaneous Drainage For Hilar Block in Gall Bladder Cancer NCT00409864 | All India Institute of Medical Sciences | N/A |
| Completed | S0202 Gemcitabine and Capecitabine for Unresectable Locally Advanced Metastatic Gallbladder Cancer or Cholangi NCT00033540 | SWOG Cancer Research Network | Phase 2 |
| Completed | Adjuvant Palliative Capecitabine and Gemcitabine in Treating Patients With Locally Advanced or Metastatic Bili NCT00073905 | Swiss Cancer Institute | Phase 2 |
| Completed | Gemcitabine and Capecitabine in Treating Patients With Advanced and/or Inoperable Cholangiocarcinoma or Carcin NCT00084942 | Roswell Park Cancer Institute | Phase 2 |
| Completed | A Feasibility Phase II Study in the Treatment of Resected Cholangiocarcinoma, Gallbladder, Pancreatic and Ampu NCT00660699 | Washington University School of Medicine | Phase 2 |
| Completed | Gemcitabine and Cisplatin for Gallbladder and Biliary Tract Cancer NCT00123825 | Dana-Farber Cancer Institute | Phase 2 |
| Terminated | Vaccine Therapy in Treating Patients With Cancer of the Gastrointestinal Tract NCT00012246 | The University of Texas Medical Branch, Galveston | Phase 2 |
| Unknown | HAI Via Interventionally Implanted Port Catheter Systems NCT00356161 | Charite University, Berlin, Germany | Phase 2 |
| Completed | Study of Gemcitabine and Carboplatin in the Treatment of Metastatic or Recurrent Cholangiocarcinoma/Gallbladde NCT00660140 | Washington University School of Medicine | Phase 2 |
| Completed | Vaccine Therapy in Treating Patients With Advanced or Metastatic Cancer NCT00027534 | Michael Morse, MD | Phase 1 |
| Completed | Combination Chemotherapy in Treating Patients With Unresectable or Metastatic Biliary Tract or Gallbladder Can NCT00009893 | Alliance for Clinical Trials in Oncology | Phase 2 |
| Withdrawn | Anonymous Testing of Pathology Specimens for BRCA Mutations in Ashkenazi Jewish Individuals Who Have Cancer NCT00588263 | Memorial Sloan Kettering Cancer Center | — |
| Completed | DX-8951f in Treating Patients With Biliary Cancer NCT00005938 | Daiichi Sankyo | Phase 2 |
| Terminated | Rebeccamycin Analogue in Treating Patients With Advanced Liver and/or Biliary Cancer NCT00005997 | Case Comprehensive Cancer Center | Phase 2 |
| Completed | Photodynamic Therapy in Treating Patients With Cancer of the Bile Duct, Gallbladder, or Pancreas NCT00003923 | Memorial Sloan Kettering Cancer Center | Phase 2 |
| Completed | Visceral Lymphatic Mapping Using Isosulfan Blue in Patients With Cancer of the Pancreas, Colon, Stomach, Small NCT00489515 | Wake Forest University Health Sciences | — |
| Completed | Dolastatin 10 in Treating Patients With Metastatic Or Recurrent Liver, Bile Duct, or Gallbladder Cancer NCT00003557 | University of Chicago | Phase 2 |
| Completed | Radiation Therapy in Treating Patients With Bile Duct, Gallbladder, or Pancreatic Cancer NCT00003411 | University of Pittsburgh | Phase 1 |
| Completed | Combination Chemotherapy in Treating Patients With Recurrent, Refractory, or Metastatic Solid Tumors or Lympho NCT00019513 | National Institutes of Health Clinical Center (CC) | Phase 1 |
| Completed | Oxaliplatin Plus Irinotecan in Treating Patients With Metastatic Gastrointestinal Cancer NCT00003427 | Memorial Sloan Kettering Cancer Center | Phase 1 |
| Completed | Irinotecan in Treating Patients With Advanced Gallbladder or Bile Duct Cancer NCT00003276 | Alliance for Clinical Trials in Oncology | Phase 2 |
| Unknown | Liposomal Doxorubicin in Treating Patients With Liver or Bile Duct Cancer NCT00003296 | Brown University | Phase 2 |
| Completed | Gemcitabine and Radiation Therapy in Treating Patients With Locally Advanced Upper Gastrointestinal Cancer NCT00544193 | City of Hope Medical Center | Phase 1 |
| Completed | Interleukin-12 in Treating Patients With Cancer in the Abdomen NCT00003046 | M.D. Anderson Cancer Center | Phase 1 |
| Completed | Biological Therapy in Treating Patients With Metastatic Cancer NCT00004604 | Duke University | Phase 1 |