Clinical Trials Directory

Trials / Sponsors / UNICANCER

UNICANCER

Academic / Other · 215 registered clinical trials54 currently recruiting.

StatusTrialPhaseStarted
Not Yet RecruitingTesting Mitazalimab in Combination With Standard Chemotherapy in Immunotherapy Resistant Advanced Biliary Trac
Biliary Tract Cancer (BTC)
Phase 2 / Phase 32026-07-01
Not Yet RecruitingClinical Trial Evaluating the Biological Activity of a New Drug Identified as Prifetrastat (PF-07248144), Comb
Metastatic (Stage IV) Melanoma
Phase 22026-05-18
Not Yet RecruitingPersonalizing Chemotherapy Selection After Surgery for Patients With Stage III Colorectal Cancer Using a Blood
Colorectal Cancer
Phase 32026-05-01
Not Yet RecruitingOptimising Adjuvant Chemotherapy Prescription in Young Patients With Hormone-dependent Breast Cancer Using Gen
Early Breast Cancer, Premenopausal Breast Cancer, HR+/HER2- Breast Cancer
Phase 32026-04-01
Not Yet RecruitingStudy Aiming to Test Whether Non-invasive Liquid Biopsies Can Safely Reduce Invasive Surveillance Methods in L
Lynch Syndrome
N/A2026-04-01
Not Yet RecruitingImmunotherapy Without Chemotherapy for Advanced Lung Cancer Patients With High PD-L1 Levels
Non Small Cell Lung Cancer (Squamous or Non Squamous)
Phase 22026-04-01
Not Yet RecruitingImmunotherapy Master Trial for Advanced Cancers
Advanced / Metastatic Solid Tumors, Advanced Malignancy
Phase 22026-04-01
Not Yet RecruitingSPECT-CT Guided ELEctive Contralateral Neck Treatment in Lateralized Oropharyngeal Cancer
Oropharyngeal Squamous Cell Carcinoma, Oropharyngeal Cancers, Oropharyngeal Carcinoma
N/A2026-04-01
Not Yet RecruitingLiver-directed Chemotherapy After Surgery of Liver Metastases of Colorectal Cancer in Patients With High Risk
Colorectal Adenocarcinoma Metastatic in the Liver, Colorectal Cancer
Phase 32026-03-01
Not Yet RecruitingTesting Ivonescimab in Combination With Chemotherapy in Patients With Metastatic Colorectal Cancers Without Li
Metastatic Colorectal Cancer
Phase 22026-03-01
RecruitingEvaluation of an Online Intervention to Educate Women at High Risk of Breast Cancer on How to Help Reduce Thei
Breast Cancer
N/A2026-02-19
RecruitingNeo-adjuvant Immunotherapy Master Trial for Localized Cancers
Localized Cancer
Phase 22026-01-21
RecruitingNeo-adjuvant Immunotherapy in Patients With Localized Melanoma
Cutaneous Melanoma, Stage III, Mucosal Melanoma
Phase 22026-01-12
Not Yet RecruitingBlood Biomarkers Based Screening for HPV-driven OPC
Head and Neck Squamous Cell Carcinoma, Anal Cancer, Human Papilloma Virus
N/A2026-01-01
Not Yet RecruitingAntibody-based PET Imaging and Treatment Response in Breast Cancer Treated With an Antibody-drug Conjugate.
Locally Advanced or Metastatic Breast Cancer
Phase 22025-12-31
RecruitingChemotherapy De-escalation in HR +, HER2-, Intermediate-risk Early Breast Cancer Treated With Adjuvant Ribocic
Breast Cancer
Phase 32025-12-18
Not Yet RecruitingStudy Evaluating Two Treatment Strategies for Rectal Cancer in Patients ≥75 Years Old
Locally Advanced Rectal Adenocarcinoma
Phase 32025-12-15
RecruitingTesting Ivonescimab in Combination With Chemotherapy in Advanced or Metastatic Gastric/Gastroesophageal Adenoc
Metastatic Esophageal Adenocarcinoma, Advanced Esophageal Adenocarcinoma, Metastatic Gastric Adenocarcinoma
Phase 22025-11-20
RecruitingDurvalumab and Tremelimumab With or Without Hepatic Arterial Infusion of Chemotherapy in Hepatocellular Carcin
Hepatocellular Carcinoma
Phase 2 / Phase 32025-11-14
RecruitingOptimal Methods to Characterize ADC Resistance in Solid Tumors and Identify Clinically Useful Biomarkers
Advanced Breast Cancer, Advanced Gastric Cancer, Advanced Urothelial Cancer
Phase 22025-11-14
RecruitingClinical Trial Evaluating the Activity of Zanidatamab for the Treatment of Patients With Solid Tumors With an
Non-Small Cell Lung Cancer, Sarcoma, Head &Amp; Neck Cancer
Phase 22025-10-30
RecruitingTesting Ivonescimab Versus FOLFOX in Advanced Biliary Tract Cancer Patients
Biliary Tract Cancer
Phase 22025-10-09
RecruitingArm Swelling Occurence in Breast Cancer Patients With Nodal Radiotherapy: Impact of Informing Them of AI-predi
Unilateral Breast Neoplasms
N/A2025-10-07
Not Yet RecruitingTesting Two Different Drugs (Sacituzumab-govitecan and Trastuzumab-deruxtecan) Combinations Prescribed in an A
Triple Negative Breast Neoplasms, Neoplasm Metastasis, HER 2 Low-expressing Breast Cancer
Phase 22025-10-01
Enrolling By InvitationDetecting Tumor DNA in the Blood of HR+/HER2-low Metastatic Breast Cancer Patients to Find Candidates for T-DX
Breast Cancer Metastatic, Breast Cancer Stage IV
Phase 22025-07-30
RecruitingPersonalizing the Use of Pembrolizumab for Patients Who Have a Strong Response in Early Triple Negative Breast
Breast Cancers, Triple Negative Breast Cancer (TNBC)
Phase 32025-07-23
RecruitingStudy Evaluating the Efficacy and Safety of Darolutamide and Stereotactic Dose Escalated Radiotherapy in Patie
High Risk Prostate Carcinoma, Prostate Cancer
Phase 32025-04-10
RecruitingEfficacy of Pemigatinib in Patients With Solid Tumors Characterized by an Alteration of the Gene FGFR in Tumor
Solid Tumor, Miscellaneous
Phase 22025-03-27
RecruitingSafety of Trifluridine/Tipiracil in Patients With Dihydropyrimidine Dehydrogenase Deficiency Diagnosed With Me
Metastatic Colorectal Cancer, Metastatic Gastroesophageal Adenocarcinoma, DPD Deficiency
Phase 22025-03-21
RecruitingCapecitabine Plus Pembrolizumab in Patients With Triple Negative Breast Cancer After Chemo-immunotherapy and S
Triple Negative Breast Neoplasms
Phase 22025-03-11
RecruitingInterest of Post-operative Chemotherapy in Patients With Localised Uterine Leiomyosarcoma Suspected of Having
Leiomyosarcoma Uterus
Phase 22025-01-27
RecruitingDecreasing Treatment for Metastatic HER2-Positive Breast Cancer With Undectable Cancer Levels in Blood Tests.
Metastatic Breast Cancer, HER2-positive Breast Cancer
Phase 22025-01-25
RecruitingDose Individualization of Chemotherapy in Patients With Gastrointestinal Cancers Lacking a Specific Liver Enzy
Digestive Cancer, Colorectal Cancer
Phase 22025-01-20
RecruitingPembrolizumab and Chemotherapy Treatment or no Treatment Guided by the Level of TILs in Resected Early-stage T
Triple-negative Breast Cancer
Phase 22024-12-27
RecruitingTreatment With Darolutamide +/- Radiation Therapy for Patients With a Castration Resistant Cancer and Metastas
Prostatic Cancer, Castration-Resistant
Phase 32024-10-07
RecruitingStandard of Care +/- 177Lu-PSMA-617 In de Novo mHSPC Patients With Poor PSA Response (PEACE6-Poor Responders)
Prostate Cancer Metastatic
Phase 32024-09-12
RecruitingTelemonitoring Platform "CUREETY TECHCARE" vs Standard of Care for mTBNC Patients Initiating a First-line Trea
Metastatic Triple-Negative Breast Carcinoma
N/A2024-07-25
RecruitingDostarlimab for Locally Advanced or Metastatic Cancer (Non-colorectal/Non-endometrial) With Tumor dMMR/MSI
Pancreatic Adenocarcinoma, Ampulla of Vater Carcinoma, Adrenocortical Carcinoma
Phase 22024-07-23
RecruitingPersonalized Medicine for Advanced Biliary Cancer Patients
Biliary Tract Neoplasms
Phase 32024-07-18
RecruitingSURVEILLE-HPV: Evaluation of HPV16 Circulating DNA as Biomarker to Detect the Recurrence, in Order to Improve
Oropharynx Squamous Cell Carcinoma
Phase 22024-04-03
RecruitingCapecitabine, Tucatinib, and Intrathecal Trastuzumab for Breast Cancer Patients With Leptomeningeal Disease
Leptomeningeal Metastasis, Leptomeningeal Disease, HER2-positive Metastatic Breast Cancer
Phase 22023-12-18
Active Not RecruitingDetection of Tumor DNA in the Blood of Patients Receiving Standard Therapy for Hormone Receptor-positive (HR+)
Breast Cancer Stage IV
Phase 22023-10-19
CompletedTesting Immunotherapy for Patients With Liver Cancer and Moderately Altered Liver Functions
Hepatocellular Carcinoma by BCLC Stage
Phase 22023-10-12
RecruitingSafety and Efficacy Analysis of an Antibody Associated With a Chemotherapy for Patients With a Triple Negative
Triple Negative Breast Cancer, Metastatic Breast Cancer
Phase 32023-10-05
RecruitingA Clinical-biological Prospective Cohort of Patients With BRAFV600E-mutated Metastatic Colorectal Cancer
Metastatic Colorectal Cancer, BRAF V600E Mutation Positive
N/A2023-07-24
RecruitingOxaliplatin ± Nivolumab in Combination With Trifluridine/Tipiracil or 5-fluorouracile in Frail Patients With A
Gastric Adenocarcinoma, Esophagus Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma
Phase 22023-06-23
RecruitingDurvalumab Maintenance After Thoracic Chemoradiotherapy in Frail Small Cell Lung Cancer Patients Whose Disease
Small Cell Lung Carcinoma
Phase 22023-03-24
RecruitingDeescalation of Endocrine Therapy Duration in Women With HR+ HER2- Breast Cancer at Very Low Risk
Breast Cancer
Phase 22022-10-12
Active Not RecruitingBinimetinib Encorafenib Pembrolizumab +/- Stereotactic Radiosurgery in BRAFV600 Melanoma With Brain Metastasis
Malignant Melanoma, BRAF V600 Mutation, Brain Metastases
Phase 22022-09-05
RecruitingTARGETed Therapy Drug MONITOring in DIGestive Oncology
Digestive Cancer, Metastatic Colorectal Cancer, Hepatocellular Carcinoma
N/A2022-08-29
RecruitingADT +/- Darolutamide in de Novo Metastatic Prostate Cancer Patients With Vulnerable Functional Ability (PEACE6
Prostate Cancer Metastatic
Phase 32022-04-19
RecruitingStudy Comparing the Standard Administration of IO Versus the Same IO Administered Each 3 Months in Patients in
Lung Cancer Metastatic, Renal Cell Carcinoma, Head and Neck Cancer
Phase 32022-03-08
Active Not RecruitingTreatment With Tucatinib in Patients With an Isolated Brain Progression of a Metastatic Breast Cancer
Metastatic Breast Cancer With a Isolated Brain Progression
Phase 22021-12-17
RecruitingStudy on the Efficacy of Treatment by Radiotherapy and Pembrolizumab in Newly Diagnosed Metastatic Head & Neck
Squamous Cell Carcinoma of Head and Neck
Phase 32021-12-01
CompletedPatient's Choice in the Reduction of Their Treatment in Women Over 65 Year With Breast Cancer
Breast Cancer
N/A2021-10-01
RecruitingComparison of Oral Cyclophosphamide vs Doxorubicin in ≥65 Years Old Advanced or Metastatic Soft Tissue Sarcoma
Advanced Soft-tissue Sarcoma, Metastatic Soft-tissue Sarcoma
Phase 32021-06-18
CompletedStudy Comparing Fibula Free-flap MR With or Without PVP in Patients With OOPC
Oropharynx Squamous Cell Carcinoma, Oral Cavity Squamous Cell Carcinoma
N/A2021-04-20
TerminatedEvaluation of Bintrafusp Alfa in Operable and Untreated Head and Neck Squamous Cell Carcinoma
Squamous Cell Carcinoma of Head and Neck
Phase 22021-02-04
TerminatedSequences Of REGorafenib And Trifluridine/Tipiracil in Patients With Metastatic Colorectal Cancer
Metastatic Colorectal Cancer
Phase 22020-11-23
SuspendedEffectiveness Assessment of Riluzole in the Prevention of Oxaliplatin-induced Peripheral Neuropathy.
Oxaliplatin-induced Peripheral Neuropathy
Phase 22020-10-28
CompletedEfficacy of Immunotherapy Plus a Drug in Patients With Progressive Advanced Mucosal Cancer of Different Locati
Squamous Cell Lung Cancer, Vulvar Cancer, Penile Cancer
Phase 22020-10-28
Active Not RecruitingProstate-cancer Treatment Using Stereotactic Radiotherapy for Oligometastases Ablation in Hormone-sensitive Pa
Oligometastatic Hormone Sensitive Prostate Cancer
Phase 32020-06-23
Active Not RecruitingEndocrine Therapy With Abemaciclib or Chemotherapy as Initial Metastatic Treatment in ER+/HER2- Breast Cancer
Cancer Metastatic
Phase 32020-06-11
CompletedCOVID-19 Detection Test in Oncology
Oncology
2020-05-23
CompletedConcordance of the IHC4 Score Performed in Local or Central Laboratory to Endopredict in ER+/HER2- Breast Canc
Breast Neoplasm Female
2020-04-24
WithdrawnEffectiveness and Tolerance of Fentanyl Citrate in Painful Pain Induced During Diagnostic or Therapeutic Exami
Breakthrough Pain
Phase 22020-02-01
Active Not RecruitingCombined Apalutamide, Radiotherapy, and LHRH Agonist in Prostate Cancer Patients After Prostatectomy
Prostate Cancer
Phase 32020-01-09
Active Not RecruitingLocoregional Treatment and Palbociclib in de Novo, Treatment Naive, Stage IV ER+, HER2- Breast Cancer Patients
Breast Cancer Stage IV, Radiotherapy, Surgery
N/A2019-10-23
CompletedStudy of DS-8201a, an Antibody Drug Conjugate for Advanced Breast Cancer Patients, With Biomarkers Analysis
Breast Tumors
Phase 22019-10-21
Active Not RecruitingDurvalumab, With Olaparib and Fulvestrant in Advanced ER+, HER2- Breast Cancer Patients.
ER-positive and HER2-negative Metastatic or Locally Advanced Breast Cancer, a Germline or Somatic BRCA Mutation, or a Deleterious Alteration of Other Genes Involved in Homologous Recombination Repair (HRR) or in MSI Status
Phase 22019-08-26
CompletedFeasibility and Tolerance of Nivolumab Neoadjuvant Immunotherapy in High Risk HPV Driven Oropharynx Cancer
Oropharynx Cancer
Phase 22019-07-25
Active Not RecruitingMy Personalized Breast Screening
Breast Screening
N/A2019-07-18
CompletedGemcitabine and Paclitaxel vs Gemcitabine Alone After FOLFIRINOX Failure in Metastatic Pancreatic Ductal Adeno
Metastatic Pancreatic Adenocarcinoma
Phase 32019-05-23
Active Not RecruitingRadiotherapy Omission in Low Risk Ductal in Situ Carcinoma Breast
DCIS, Breast Cancer, Low Risk DCIS
N/A2019-05-10
WithdrawnImpact of Immunoscore Colon Test on Adjuvant Therapeutic Strategy in Non-Metastatic Colon Cancer
Colonic Neoplasms
N/A2019-05-01
WithdrawnOligometastases of the LIVer Treated With Chemotherapy With ou Without Extracranial Stereotactic Body Radiatio
Liver Metastases, Colorectal Cancer
N/A2019-04-15
TerminatedRegorafenib Combined With Irinotecan as Second-line in Patients With Metastatic Gastro-oesophageal Adenocarcin
Adenocarcinoma of the Stomach, Adenocarcinoma of the Gastroesophageal Junction
Phase 1 / Phase 22019-02-07
Active Not RecruitingAtezolizumab Plus One-year BCG Bladder Instillation in BCG-naive High-risk Non-muscle Invasive Bladder Cancer
Bladder Cancer
Phase 32019-01-17
Active Not RecruitingAtezolizumab After Chemo-radiotherapy for MIBC Patients Not Eligible for Radical Cystectomy
Bladder Cancer
Phase 22018-12-14
CompletedAssociation of Radiochemotherapy and Immunotherapy for the Treatment of Unresectable Oesophageal caNcer
Esophagus Cancer, Unresectable Malignant Neoplasm
Phase 22018-12-05
CompletedTreatment of Metastatic Castrate Resistant Prostate Cancer Patients According to Circulating Tumor Cells Kinet
Prostate Carcinoma, Castration-resistant Prostate Cancer, Circulating Tumor Cells
Phase 22018-11-15
Active Not RecruitingMifamurtide Combined With Post-operative Chemotherapy for Newly Diagnosed High Risk Osteosarcoma Patients
Osteosarcoma
Phase 22018-10-23
Active Not RecruitingEfficacy of Repeat Stereotactic Radiation in Patients With Intraprostatic Tumor Recurrence
Local Recurrence of Malignant Tumor of Prostate
N/A2018-10-18
CompletedA Patient Consensus for the Research in Supportive Care in French Cancer Care Centers: the CyPRES Project
Cancer Patients
2018-10-10
CompletedImproving SUrgery of Liver Metastases: a Trial of the Arterial Chemotherapy Network
Colorectal Cancer Metastatic
Phase 22018-07-25
Active Not RecruitingStandard Treatment +/- SBRT in Solid Tumors Patients With Between 1 and 5 Bone-only Metastases
Metastatic Breast Cancer, Metastatic Lung Cancer, Metastatic Prostate Cancer
N/A2018-07-24
Active Not RecruitingIdentifying the Predictive Factors of Response to PD-1 or PD-L1 Antagonists
Melanoma, Non Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma
N/A2018-06-27
CompletedMetronomic Oral Vinorelbine Plus Anti-PD-L1/Anti-CTLA4 ImmunothErapy in Patients With Advanced Solid Tumours
Advanced Solid Tumours, Breast Cancer, Head and Neck Cancer
Phase 1 / Phase 22018-06-20
Active Not RecruitingAdjuvant Radiotherapy in Patients With Pathological High-risk Bladder Cancer (GETUG-AFU 30)
Patients With High-risk MIBC
N/A2018-04-19
TerminatedSAFIR-PI3K A Phase II Randomized Maintenance Trial Comparing Alpelisib and Fulvestrant Versus Chemotherapy in
Breast Cancer, PI3K, Alpelisib
Phase 22018-03-15
CompletedStudy on Androgen Receptor and Triple Negative Breast Cancer
Breast Cancer Female, Triple Negative and Androgen Receptor Positive
Phase 22018-03-14
Active Not RecruitingPD-1 Inhibitor and Chemotherapy With Concurrent Irradiation at Varied Tumour Sites in Advanced Non-small Cell
Non Small Cell Lung Cancer, Non Small Cell Lung Cancer Metastatic, Non-Small Cell Carcinoma of Lung, TNM Stage 4
Phase 32018-01-24
RecruitingEvolution of the Therapeutic Care in Lung Cancer in France Since 2015 (ESME LC)
Lung Cancer
2017-10-02
Active Not RecruitingInvestigation of Tumour Spectrum of Germline Mutations in Breast and Ovarian Cancer Genes.
Hereditary Breast and Ovarian Cancer, Mutation
N/A2017-09-21
Active Not RecruitingQUALIOR Feasibility and Efficacy of a Supervised Home-based Standard Physical Exercise Program
Home Based Standardised Adapted Physical Activity Programme, Patients Taking Oral Targeted Therapy for Metastatic Cancer
N/A2017-07-11
CompletedNivolumab in Recurrent and/or Metastatic SCCHN
Recurrent and/or Metastatic Platinum-refractory SCCHN
Phase 22017-07-07
CompletedSecured Access to Pembrolizumab for Patients With Selected Rare Cancer Types
Sarcoma, Ovarian Neoplasm, Central Nervous System Neoplasm
Phase 22017-07-05
CompletedSecured Access to Nivolumab for Adult Patients With Selected Rare Cancer Types
Carcinoma, Renal Cell, Head and Neck Neoplasm, Skin Neoplasms
Phase 22017-06-16
WithdrawnAssessment of Genomic Test Impact on Shared Decision of Adjuvant Chemotherapy in ER-positive, Her2-negative Ea
ER-positive Her2-negative Early Breast Cancer
N/A2017-05-01
Active Not RecruitingTracking Triple-negative Breast Cancer Evolution Through Therapy
Triple-Negative Breast Neoplasm
N/A2017-04-14
SuspendedEvolution of the Therapeutic Care in Ovarian Cancer From 2011
Ovarian Cancer
2017-04-01
CompletedIRinotecan and Oxaliplatin for Colon Cancer in Adjuvant Setting
Colon Cancer (High-risk Stage III: pT4N1 or pT1 to 4 N2)
Phase 32017-03-27
CompletedNivolumab in Recurrent or Metastatic Salivary Gland Carcinoma of the Head and Neck
Salivary Gland Carcinoma, Metastatic Cancer, Recurrent Cancer
Phase 22017-03-24
CompletedPAlbociclib and Circulating Tumor DNA for ESR1 Mutation Detection
Metastatic Breast Cancer
Phase 32017-03-22
CompletedDurvalumab and Endocrine Therapy in ER+/Her2- Breast Cancer After CD8+ Infiltration Effective Immune-Attractan
Breast Cancer, Estrogen Receptor Positive Tumor, Menopause
Phase 22017-02-15
CompletedPhase I Evaluating the Combination of Ribociclib+Capecitabine in Locally Advanced/Metastatic Breast Cancer HER
Breast Cancer
Phase 12017-02-02
CompletedEXPRESS: EXcePtional RESponSe - Exceptional and Unexpected Response to Targeted Therapies
Metastatic Cancers
N/A2016-12-01
Active Not RecruitingComparison FOLFIRINOX Panitumumab vs mFOLFOX6 Panitumumab in RAS/B-RAF Wild-type Metastatic Colorectal Cancer
Metastatic Colorectal Cancer
Phase 22016-12-01
Active Not RecruitingEvaluation of Lymphadenectomy and Chemotherapy TIP on Inguinal Lymph Nodes in Squamous Cell Carcinoma of the P
Penile Cancer, Squamous Carcinoma
Phase 22016-10-17
CompletedProspective Study Assessing EndoPredict® Genomic Test Impact on Shared Decision of Adjuvant Chemotherapy in Pa
Breast Cancer
N/A2016-09-01
Active Not RecruitingHypofractionated vs Standard Radiotherapy in Breast Cancer With an Indication for Regional Lymph Node Irradiat
Breast Cancer Female
N/A2016-09-01
TerminatedCopanlisib in Association With Cetuximab in Patients With Recurrent and/or Metastatic Head and Neck Squamous C
Carcinoma, Squamous Cell of Head and Neck
Phase 1 / Phase 22016-06-01
CompletedA Study to Assess the Efficacy of Rucaparib in Metastatic Breast Cancer Patients With a BRCAness Genomic Signa
Metastatic Breast Cancer
Phase 22016-03-01
CompletedNeoadjuvant Treatment for Advanced Rectal Carcinoma
Rectal Carcinoma
Phase 32016-01-07
CompletedNivolumab in Patients With Metastatic Renal Cell Carcinoma Who Have Progresses During or After Prior Systemic
Metastatic Renal Cell Carcinoma
Phase 22016-01-01
CompletedA Randomized Phase III Trial Comparing Folfirinox to Gemcitabine in Locally Advanced Pancreatic Carcinoma
Pancreatic Cancer, Carcinoma
Phase 32015-10-23
CompletedMolecular Alterations Associated With Resistance to Endocrine Therapy and Impacting Treatment With mTOR Inhibi
Metastatic Breast Cancer
N/A2015-05-19
CompletedNeoadjuvant Phase II Trial in Patients With T1c Operable, HER2-positive Breast Cancer According to TOP2A Statu
Breast Cancer
Phase 22015-01-01
CompletedEfficacy of Letrozole + Palbociclib Combination as Neoadjuvant Treatment of Stage II-IIIA PAM 50 ROR-defined L
Neoadjuvant Operable Breast Cancer
Phase 22015-01-01
CompletedStudy of Gemcitabine+Platinum Salt+Bevacizumab Combination for Metastatic Collecting Duct Carcinoma (GETUG-AFU
Collecting Duct Carcinoma (Kidney)
Phase 22014-12-01
Active Not RecruitingPhase 2 Study Assessing Secured Access to Vemurafenib for Patients With Tumors Harboring BRAF Genomic Alterati
Solid Tumors, Hematologic Cancers, Metastatic Cancers
Phase 22014-10-13
Active Not RecruitingA Phase II Study Evaluating Efficacy and Safety of Regorafenib in Patients With Metastatic Bone Sarcomas
Ewing Sarcomas, Chondrosarcomas, Osteosarcomas
Phase 22014-09-01
RecruitingEvolution of the Therapeutic Care in Metastatic Breast Cancer From 2008
Metastatic Breast Cancer
2014-07-01
CompletedSAFIR02_Lung - Efficacy of Targeted Drugs Guided by Genomic Profiles in Metastatic NSCLC Patients
Non-small Cell Lung Cancer Metastatic
Phase 22014-04-23
Active Not RecruitingSAFIR02_Breast - Efficacy of Genome Analysis as a Therapeutic Decision Tool for Patients With Metastatic Breas
Metastatic Breast Cancer
Phase 22014-04-07
Active Not RecruitingA Phase III of Cabazitaxel and Pelvic Radiotherapy in Localized Prostate Cancer and High-risk Features of Rela
Adenocarcinoma of Prostate, Progression of Prostate Cancer
Phase 32013-12-01
CompletedTreatment After Irinotecan-based Frontline Therapy: Maintenance With Erbitux (in Patients wtRAS mCRC)
Metastatic Colorectal Cancer
Phase 22013-11-22
Active Not RecruitingA Phase III Study for Patients With Metastatic Hormone-naïve Prostate Cancer
Metastatic Prostate Cancer
Phase 32013-11-13
CompletedPazopanib in Patients With Progressive Recurrent and/or Metastatic Salivary Gland Carcinoma
Salivary Gland Carcinoma
Phase 22013-08-26
CompletedPhase 2 Study Assessing Efficacy and Safety of Crizotinib in Patients Harboring an Alteration on ALK, MET or R
Hematologic Cancers, Solid Tumors, Metastatic Cancer
Phase 22013-08-01
CompletedAbiraterone Acetate in Molecular Apocrine Breast Cancer
Breast Cancer
Phase 22013-07-01
Active Not RecruitingSafety Study of Adding Everolimus to Adjuvant Hormone Therapy in Women With High Risk of Relapse, ER+ and HER2
Primary Non-metastatic Breast Cancer, Who Remain Disease-free
Phase 32013-03-01
Active Not RecruitingComparison of HT Concomitant With RT vs RT Alone in Patients With a Detectable PSA After Prostatectomy
Adenocarcinoma of Prostate
Phase 22012-12-01
CompletedRadiotherapy Plus Hormone Therapy in Biochemically-relapsing Prostate Cancer Patients Following Surgery
Biochemically-relapsing Prostate Adenocarcinoma Following Radical Prostatectomy
Phase 1 / Phase 22012-12-01
CompletedDual Targeting of EGFR With Cetuximab and Afatinib to Treat Refractory wtKRAS Metastatic Colorectal Cancer
Metastatic Colorectal Cancer
Phase 22012-10-01
CompletedCohort Study of Prospective Validation of Predictive Factors and Biological Imaging of Response to Bevacizumab
Metastatic, Breast Cancer
2012-06-01
CompletedTrial Comparing Adjuvant Chemotherapy With Gemcitabine Versus mFolfirinox to Treat Resected Pancreatic Adenoca
Pancreatic Adenocarcinoma (Ductal Adenocarcinoma)
Phase 32012-04-16
Active Not RecruitingAdjuvant Systemic Treatment for (ER)-Positive HER2-negative Breast Carcinoma in Women Over 70 According to Gen
Breast Cancer
Phase 32012-04-12
CompletedA Phase II, Open-Label, Multicenter Trial of Cabazitaxel in Patients With Recurrent or Metastatic Head and Nec
Recurrent Head and Neck Cancer, Metastatic Head and Neck Cancer
Phase 22012-04-01
RecruitingChronic Toxicities Related to Treatment in Patients With Localized Cancer
Breast Cancer Nos Metastatic Recurrent, Early Lung Cancer
N/A2012-02-20
CompletedEfficacy of Neoadjuvant Folfirinox Regimen in Patients With Resectable Locally Advanced Rectal Cancer
Cancer of the Rectum
Phase 32012-01-01
CompletedResearch of Biomarkers of Activity and Efficacy of BIBW2992 in Untreated Non-metastatic HNSCC Patients
Carcinoma, Squamous Cell of Head and Neck
Phase 22012-01-01
CompletedEfficacy of Gemcitabine With Pazopanib as Second Line Treatment in Patient With Metastatic or Relapsed Uterine
Leiomyosarcoma
Phase 22011-09-01
Active Not RecruitingEvaluation of Adjuvant Hormonal Treatment for 24 Months After Radical Prostatectomy in High Risk of Recurrence
Metastases
Phase 32011-07-01
CompletedHigh Throughput Technologies to Drive Breast Cancer Patients to Specific Phase I/II Trials of Targeted Agents
Metastatic Breast Cancer
2011-05-01
Active Not RecruitingHyperthermic Intra-Peritoneal Chemotherapy (HIPEC) in Relapse Ovarian Cancer Treatment
Ovarian Epithelial Cancer Recurrent
Phase 32011-04-26
CompletedChemotherapies Associated With Targeted Therapies on the Resection Rate of Hepatic Metastases
Colorectal Cancer
Phase 22011-02-01
CompletedMEGA (Met or EGFR Inhibition in Gastroesophageal Adenocarcinoma): FOLFOX Alone or in Combination With AMG 102
Malignant Neoplasm of Esophagus, Malignant Neoplasm of Stomach
Phase 22011-01-01
Active Not RecruitingStandard or Hypofractionated Radiotherapy Versus Accelerated Partial Breast Irradiation (APBI) for Breast Canc
Breast Cancer, Lumpectomy
N/A2010-12-27
CompletedFeasibility of a Chemotherapy With Docetaxel-Prednisone for Castration-resistant Metastatic Prostate Cancer El
Prostate Cancer
Phase 22010-12-09
CompletedEfficacy of Chemotherapy, Associated to Either Cetuximab or Bevacizumab, in KRAS Wild-type Metastatic Colorect
Colorectal Cancer
Phase 22010-12-01
CompletedStudy With Pazopanib in Combination With Cisplatin (CDDP) in Patients With Advanced Solid Tumors
Solid Tumors, Metastatic Cancer
Phase 12010-06-01
CompletedI-MVAC +/- Panitumumab as First-line Treatment of Advanced Urothelial Carcinoma Without H-Ras Nor K-Ras Mutati
Infiltrating Urothelial Carcinoma, KRAS Gene Mutation
Phase 32010-06-01
CompletedEvaluating Lapatinib + Capecitabine in Patients Aged 70 and Over With HER2 Metastatic Breast Cancer.
Metastatic Breast Cancer, 70 Years Old Patients and Over, After One Line of Chemotherapy With Trastuzumab
Phase 22009-12-01
CompletedGemcitabine Hydrochloride and Oxaliplatin or Observation in Treating Patients With Biliary Tract Cancer That H
Extrahepatic Bile Duct Cancer, Gallbladder Cancer, Liver Cancer
Phase 32009-07-01
CompletedLapatinib Ditosylate and Capecitabine in Treating Patients With Stage IV Breast Cancer and Brain Metastases
Breast Cancer, Metastatic Cancer
Phase 22009-04-01
TerminatedRadiation Therapy, Cisplatin, Fluorouracil, and Cetuximab in Treating Patients With Locally Advanced Anal Canc
Anal Cancer
Phase 22009-03-01
CompletedEfficacy and Tolerance Study of Bevacizumab in Her2- Inflammatory Breast Cancer Patients
Breast Cancer
Phase 22009-01-01
Active Not RecruitingRadiation Therapy in Treating Patients Receiving Hormone Therapy for Prostate Cancer (GETUG-AFU 18)
Prostate Cancer
N/A2008-10-01
CompletedLetrozole in Preventing Breast Cancer in Postmenopausal Women With a BRCA1 or BRCA2 Mutation
brca1 Mutation Carrier, brca2 Mutation Carrier, Breast Cancer
Phase 32008-05-01
CompletedTriptorelin and Radiation Therapy in Treating Patients Who Have Undergone Surgery for Intermediate-Risk Stage
Prostate Cancer
Phase 32008-04-07
TerminatedTrastuzumab With or Without Everolimus in Treating Women With Breast Cancer That Can Be Removed By Surgery
Breast Cancer
Phase 22008-04-01
CompletedRadiation Therapy + Combination Chemotherapy as 1st-Line Therapy for Patients With Inoperable Esophageal Cance
Esophageal Cancer
Phase 2 / Phase 32008-03-01
CompletedSystemic Chemotherapy With or Without Intraperitoneal Chemohyperthermia in Treating Patients Undergoing Surger
Colorectal Cancer, Primary Peritoneal Cavity Cancer
Phase 32008-02-01
TerminatedRadiation Therapy, Chemotherapy, and Cetuximab Followed by Surgery, Chemotherapy, and Cetuximab in Treating Pa
Colorectal Cancer
Phase 22007-10-29
CompletedEfficacy of Anastrozole and Fulvestrant in Patients With ER Positive, HER2 Negative, Operable Breast Cancer
Breast Cancer
Phase 22007-10-01
CompletedSunitinib as First-Line Therapy in Treating Patients With Locally Advanced Metastatic Papillary Renal Cell Can
Kidney Cancer
Phase 22007-09-05
CompletedSafety and Efficacy Comparison of Docetaxel and Ixabepilone in Non Metastatic Poor Prognosis Breast Cancer
Breast Cancer
Phase 32007-09-01
CompletedLapatinib and Vinorelbine in Treating Women With HER2-Overexpressing Locally Advanced or Metastatic Breast Can
Breast Cancer
Phase 12007-06-01
Active Not RecruitingCombined Chemotherapy With or Without Zoledronic Acid for Patients With Osteosarcoma
Sarcoma
Phase 32007-03-01
CompletedPositron Emission Tomography Using 3'-Deoxy-3'-(18F) Fluorothymidine in Treating Women With Locally Advanced C
Breast Cancer
N/A2006-11-01
CompletedRadiation Therapy With or Without Goserelin in Treating Patients Who Have Undergone Surgery for Recurrent or R
Prostate Cancer
Phase 32006-10-01
CompletedBevacizumab and Combination Chemotherapy as First-Line Therapy in Treating Patients With Metastatic Colorectal
Colorectal Cancer
Phase 22006-03-23
CompletedDoxorubicin and Cyclophosphamide in Treating Older Women With Stage I, Stage II, or Stage III Breast Cancer Th
Breast Cancer, Cognitive/Functional Effects, Depression
Phase 22006-01-01
CompletedRadiation Therapy and Capecitabine With or Without Oxaliplatin in Treating Patients Who Are Undergoing Surgery
Colorectal Cancer
Phase 32005-11-08
CompletedGemcitabine With or Without Docetaxel as Second-Line Therapy in Treating Patients With Metastatic or Relapsed,
Sarcoma
Phase 22005-10-01
CompletedDocetaxel in Treating Older Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Lung Cancer
Phase 22005-06-01
TerminatedDocetaxel in Treating Older Women With Metastatic Breast Cancer
Breast Cancer
Phase 22005-05-01
CompletedPaclitaxel in Treating Patients With Locally Advanced or Metastatic Soft Tissue Angiosarcoma or Lymphangiosarc
Sarcoma
Phase 22005-02-01
CompletedCombination Chemotherapy as First-Line Therapy in Treating Patients With Metastatic Pancreatic Cancer
Pancreatic Cancer
Phase 2 / Phase 32004-11-01
CompletedHormone Therapy and Docetaxel or Hormone Therapy Alone in Treating Patients With Metastatic Prostate Cancer
Prostate Cancer
Phase 32004-10-18
CompletedImatinib Mesylate in Treating Patients With Recurrent or Refractory Fibromatosis
Desmoid Tumor
Phase 1 / Phase 22004-09-01
CompletedRadiation Therapy in Treating Older Women Who Are Undergoing Surgery for Stage I or Stage II Breast Cancer
Breast Cancer
Phase 22004-07-01
CompletedCombination Chemotherapy in Treating Patients With Stage II or Stage III Germ Cell Tumors
Extragonadal Germ Cell Tumor, Teratoma, Testicular Germ Cell Tumor
Phase 32003-11-26
CompletedRadiation Therapy and Docetaxel With Either Fluorouracil or Cisplatin as First-Line Therapy in Treating Patien
Pancreatic Cancer
Phase 22003-10-06
CompletedTriptorelin, Flutamide, and External-Beam Radiation Therapy or External-Beam Radiation Therapy Alone in Treati
Prostate Cancer
Phase 32003-09-10
CompletedCapecitabine and Oxaliplatin in Treating Older Patients With Metastatic Colorectal Cancer
Colorectal Cancer
Phase 22003-06-30
TerminatedEvaluation of Hysterectomy After Chemoradiation Therapy for Stage IB2/II Cervical Cancer
Stage IB2 Cervical Cancer, Stage II Cervical Cancer, Adenocarcinoma
Phase 32003-05-01
CompletedHormone Therapy With or Without Docetaxel And Estramustine in Treating Patients With Prostate Cancer That is L
Prostate Cancer
Phase 32002-11-14
CompletedAllogeneic Stem Cell Transplant in Treating Patients With Metastatic Kidney Cancer
Kidney Cancer
Phase 22002-11-04
TerminatedCombination Chemotherapy Compared With Observation After Surgery in Treating Women With Relapsed Nonmetastatic
Breast Cancer
Phase 32002-11-01
CompletedCombination Chemotherapy in Treating Women With Stage I Breast Cancer
Breast Cancer
Phase 32002-08-01
CompletedComparison of Combination Chemotherapy Regimens in Treating Patients With Metastatic Colorectal Cancer
Colorectal Cancer
Phase 22002-07-23
CompletedCombination Chemotherapy With or Without Trastuzumab in Treating Women With Breast Cancer
Breast Cancer
Phase 32001-06-01
CompletedInterest of Maintenance Chemotherapy After Induction Treatment for Inflammatory Breast Cancer
Inflammatory Breast Cancer
Phase 32000-10-01
CompletedComparison of Radiation Therapy Regimens in Treating Patients With Localized Prostate Cancer
Prostate Cancer
Phase 31999-09-01
CompletedHydroxyurea in Treating Patients With Recurrent and/or Unresectable Meningioma
Brain and Central Nervous System Tumors
Phase 21999-07-01
TerminatedSecond-look Surgery With or Without Intraperitoneal Chemotherapy in Treating Patients With Recurrent Colorecta
Colorectal Cancer, Metastatic Cancer, Primary Peritoneal Cavity Cancer
Phase 21999-07-01
CompletedCombination Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver
Colorectal Cancer, Metastatic Cancer
Phase 21999-04-04
CompletedSurgery Plus Combination Chemotherapy and Radiation Therapy in Treating Patients With Cancer of the Urinary Tr
Bladder Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter, Urethral Cancer
Phase 21999-04-01
CompletedCombination Chemotherapy Plus Radiation Therapy in Treating Patients With Head and Neck Cancer
Head and Neck Cancer
Phase 21999-02-01
CompletedCombination Chemotherapy Plus Radiation Therapy in Treating Patients With Stage II or Stage III Anal Cancer
Anal Cancer
Phase 31999-01-04
CompletedRadiation Therapy With or Without Combination Chemotherapy in Treating Patients With Advanced Cancer of the Or
Head and Neck Cancer
Phase 31998-10-01
TerminatedMethylprednisolone With or Without Doxorubicin in Treating Patients With Metastatic Prostate Cancer
Prostate Cancer
Phase 31998-10-01
CompletedCombination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Small Cell Lung C
Lung Cancer
Phase 21998-09-01
CompletedCombination Chemotherapy With or Without Irinotecan in Treating Patients With Stage III Colon Cancer
Colorectal Cancer
Phase 31998-07-22
TerminatedCombination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Germ Cell Tumors
Childhood Germ Cell Tumor, Extragonadal Germ Cell Tumor, Ovarian Cancer
Phase 21998-03-01
CompletedCombination Chemotherapy in Treating Patients With Metastatic Kidney Cancer
Kidney Cancer
Phase 21998-03-01
CompletedRadiation Therapy in Treating Patients With Stage I, Stage II, or Stage III Prostate Cancer
Prostate Cancer
Phase 31997-12-01
TerminatedDiagnostic Study to Identify Sentinel Lymph Nodes in Women With Stage I or Stage II Breast Cancer
Breast Cancer
N/A1997-09-01
CompletedCombination Chemotherapy in Treating Children With Non-Hodgkin's Lymphoma
Lymphoma
Phase 31997-02-01
CompletedSurgery With or Without Combination Chemotherapy in Treating Patients With Cancer of the Esophagus
Esophageal Cancer, Gastric Cancer
Phase 31996-10-01
CompletedCombination Chemotherapy in Treating Patients With Extensive Stage Small Cell Lung Cancer
Lung Cancer
Phase 31996-03-01
CompletedHigh Dose Chemotherapy Plus Peripheral Stem Cell Transplantation Compared With Standard Therapy in Treating Wo
Breast Cancer
Phase 31994-12-01
CompletedCombination Chemotherapy With Bone Marrow Transplantation in Treating Men With Germ Cell Tumors
Extragonadal Germ Cell Tumor, Testicular Germ Cell Tumor
Phase 31994-02-01