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Active Not RecruitingNCT03169075

QUALIOR Feasibility and Efficacy of a Supervised Home-based Standard Physical Exercise Program

Study Evaluating the Feasibility and Efficacy of a Supervised Home-based Standard Physical Exercise Program, for Metastatic Cancer Patients Receiving Oral Targeted Therapy: The UNICANCER SdS 01 QUALIOR Study

Status
Active Not Recruiting
Phase
N/A
Study type
Interventional
Enrollment
190 (actual)
Sponsor
UNICANCER · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This phase II-III study will be randomized (2:1) patients starting first-line oral targeted therapies (OTT) for metastatic cancer between an individualized supervised physical exercise programs (SPEP) by a personal coach, and recommended physical exercises via a booklet. Eligible patients will have received ≤2 lines of metastatic chemotherapy, Eastern Cooperative Oncology Group Performance status (ECOG PS) ≤2, controlled pain (visual analogue scale (VAS) \<3/10), and life expectancy ≥3 months.

Conditions

Interventions

TypeNameDescription
BEHAVIORALSupervised physical exercise programsA weekly supervised physical activity session of 60 min at the patient's home is planned for 3 months. These sessions will be supervised by an educator or physiotherapist trained, with respect to the pathology and the clinical study, specifically for this activity (Fédération Française Sport et Cancer) . The proposed exercises will be normalized and adapted to each patient's profile. Self reported questionnaires: FACT-F, FACT-G, EQ-5D, FAACT module AC/S, FACT-Gog, HADS, IPAQ, Evaluation by a coach VAE
BEHAVIORALAdapted physical activityProgram based on the recommendations for performing a physical activity. A booklet containing physical activity recommendations will be given to the patients after randomization. The weekly sessions at the patients home for the experimental group (Program A) must begin as soon as possible within the 15 days after starting oral targeted therapy. Self reported questionnaires: FACT-F, FACT-G, EQ-5D, FAACT module AC/S, FACT-Gog, HADS, IPAQ

Timeline

Start date
2017-07-11
Primary completion
2024-09-30
Completion
2028-07-11
First posted
2017-05-30
Last updated
2024-11-12

Locations

15 sites across 1 country: France

Source: ClinicalTrials.gov record NCT03169075. Inclusion in this directory is not an endorsement.