| Recruiting | Concordance and Discordance in the Assessment of Volume Status in Home Dialysis Patients: A Comparison of Modi NCT07178470 | Indiana University | — |
| Recruiting | Timing of Renal Replacement Therapy in the Critically Ill Patients NCT03629977 | Karolinska University Hospital | — |
| Recruiting | Timing and Dose of Fluid Deresuscitation in Critically Ill Patients NCT07275658 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | — |
| Not Yet Recruiting | Proactive Hemodynamic Management During Cytoreductive Surgery and HIPEC NCT07070973 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | N/A |
| Completed | Comparing Natriuretic Effects of ER Torsemide to IR Torsemide in Patients With Heart Failure NCT06995144 | Sarfez Pharmaceuticals, Inc. | Phase 4 |
| Enrolling By Invitation | Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates 2.0 NCT06823115 | Indiana University | — |
| Not Yet Recruiting | Naturally Controlled Decongestion Using Renal Independent System in ADHF Patients, a European Registry NCT06401109 | AquaPass Medical Ltd. | N/A |
| Not Yet Recruiting | Investigation of Novel and Established Therapies in a Human Intravenous Lipopolysaccharide Model of Sepsis NCT06626984 | Belfast Health and Social Care Trust | Phase 1 / Phase 2 |
| Recruiting | Muscle and Subcutaneous Tissue Variation by Ultrasound and Impedance Linked to Fluid Balance in ICU Patients NCT06697470 | Dr F Duprez | — |
| Not Yet Recruiting | The Efficient PICU Fluid Care Evaluation NCT06644508 | Radboud University Medical Center | N/A |
| Recruiting | Inferior Vena Cava Collapsibility Index Guide for Preoperative Fluid Therapy in Preeclampsia NCT06539026 | Ain Shams University | N/A |
| Not Yet Recruiting | Fluid Status and Body Composition Analysis by Bioelectrical Impedance in Patients After Cardiac Surgery (FLUBI NCT06498375 | University Medical Centre Ljubljana | — |
| Not Yet Recruiting | Macrohemodynamic Impact of Fluid Removal With Net Ultrafiltration in Patients With Continuous Renal Replacemen NCT06425289 | Hospices Civils de Lyon | — |
| Unknown | Role of Active Deresuscitation After Resuscitation: NCT06326112 | Unity Health Toronto | Phase 2 |
| Completed | Pharmacokinetics and Pharmacodynamics of Subcutaneous vs Intravenous Furosemide in Healthy Volunteers NCT06167707 | scPharmaceuticals, Inc. | Phase 1 |
| Recruiting | Fluid Administration and Fluid Accumulation in the Intensive Care Unit NCT06258616 | Nordsjaellands Hospital | — |
| Recruiting | Evaluating Fluid Responsiveness in ICU Patients Using VTI and Trendelenburg Positioning NCT06418022 | Lenox Hill Hospital | N/A |
| Completed | Intrarenal Venous Flow Change During Fluid Removal in Critically Ill Patients: A Prospective Exploratory Study NCT06216119 | Mahidol University | — |
| Completed | Perfusion Parameters and Outcome During a Standardized Deresuscitation Strategy with Net Ultrafiltration: a Re NCT06899880 | Hospices Civils de Lyon | — |
| Recruiting | Early Deresuscitation Strategy Driven by Tissue Perfusion in Renal Replacement Therapy in Patients With Acute NCT05817539 | Hospices Civils de Lyon | N/A |
| Unknown | Goal-Directed Fluid Therapy in Patients Undergoing Lower Limb Surgeries NCT06133257 | Zagazig University | N/A |
| Unknown | Optimization of Prime Fluid Strategy to Preserve Microcirculatory Perfusion During Cardiac Surgery With Cardio NCT05647200 | Amsterdam UMC, location VUmc | N/A |
| Completed | Hemodynamic Effects of Variations in Net Ultrafiltration Rate During Continuous Renal Replacement Therapy. NCT06071026 | Centre Hospitalier Universitaire de Nīmes | N/A |
| Unknown | Neutral Versus Liberal fLuId In Traumatic Brain Injury: a Randomised Controlled Trial NCT05983549 | Universita degli Studi di Genova | N/A |
| Completed | The Ratio of Femoral Vein Diameter to Femoral Artery Diameter to Predict Fluid Responsiveness in Children NCT05992246 | Tanta University | — |
| Completed | Fluid Responsiveness in Post-cardiac Surgery NCT05957003 | Tanta University | N/A |
| Completed | CPB Prime Fluid Strategies to Preserve Mcirocirculatory Perfusion NCT05647057 | Amsterdam UMC, location VUmc | N/A |
| Recruiting | Comparing the Diagnostic Sensitivity and Specificity of Pleural Fluid N-Terminal Pro B-type Natriuretic Peptid NCT05797649 | Chinese University of Hong Kong | — |
| Unknown | Primary Clinical Evaluation of Wearable Filtrating Artificial Kidney Device for On-site Medical Rescue NCT05906355 | Chinese PLA General Hospital | N/A |
| Recruiting | Thoracic Fluid Content During Stabilization and Therapeutic De-escalation in Septic Shock NCT06572995 | University Hospital, Brest | — |
| Completed | THIRST Alert Trial NCT05869656 | University College, London | N/A |
| Completed | Determinants of Portal Vein Pulsatility Index NCT06582368 | Institutul de Urgenţă pentru Boli Cardiovasculare Prof.Dr. C.C. Iliescu | — |
| Recruiting | ULtrafiltration-Rate Induced CArdiac Strain (ULRICA) - Study NCT06153888 | Umeå University | N/A |
| Completed | Intradıalytıc Weıght Control In Hemodıalysıs Patıents NCT07030361 | Balikesir University | N/A |
| Recruiting | Association Between Venous Excess Ultrasound Grading System and Acute Kidney Injury in the ICU Population NCT06585722 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | — |
| Completed | Peroperative Fluid Management in Major Gynecological Cancer Surgeries NCT06101498 | Bakirkoy Dr. Sadi Konuk Research and Training Hospital | N/A |
| Withdrawn | Retrograde Autologous Priming and Mannitol for Reducing Hemodilution in Cardiac Surgery NCT04870073 | Hamilton Health Sciences Corporation | Phase 3 |
| Completed | Feasibility of Slow Continuous UltraFiltration For Deresuscitation in Critically Ill Patients NCT05431491 | Belfast Health and Social Care Trust | N/A |
| Terminated | Restrictive Versus Liberal Rate of Extracorporeal Volume Removal Evaluation in Acute Kidney Injury NCT05306964 | University of Pittsburgh | N/A |
| Withdrawn | Effect of High-Flow Nasal Cannula on IVC Measurements Using Point of Care Ultrasound NCT05264454 | Nova Scotia Health Authority | N/A |
| Recruiting | Ultrafiltration Versus IV Diuretics in Worsening Heart Failure NCT05318105 | Nuwellis, Inc. | N/A |
| Recruiting | Interview Study of Adult and Child Patients and Parents of Children With Swelling Due to Nephrotic Syndrome. NCT05505500 | University of Michigan | — |
| Completed | Tidal Volume Challenge to Assess Volume Responsiveness NCT05254951 | Attikon Hospital | N/A |
| Completed | Effect on Kidney Function Recovery Guiding Decongestion With VExUS in Patients With Cardiorenal Syndrome 1 NCT05927285 | Hospital Civil de Guadalajara | N/A |
| Completed | Non-invasive Assessment to Predict Tolerance to Fluid Removal on Intermittent Kidney Replacement Therapy NCT05270759 | Centre hospitalier de l'Université de Montréal (CHUM) | — |
| Completed | Influence of Intraoperative Fluid Balance on the Incidence of Adverse Events in Pediatric Cardiac Surgery NCT05142046 | Brugmann University Hospital | — |
| Unknown | VExUS-guided Fluid Management in Patients With Acute Kidney Injury in the Intensive Care Unit NCT05240833 | Hospital de Clinicas de Porto Alegre | N/A |
| Recruiting | Lung Ultrasound-Guided Fluid Deresuscitation in ICU Patients NCT05188092 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | N/A |
| Completed | Implementation of Fluid Strategies Using Real-time Bioelectrical Analyzer in Surgical Intensive Care Unit (SIC NCT06097923 | Seoul St. Mary's Hospital | N/A |
| Completed | Atrial Natriuretic Peptide in Assessing Fluid Status NCT05070819 | Petrovsky National Research Centre of Surgery | N/A |
| Unknown | Fluid unLoading On Weaning (FLOW) NCT04496583 | Pontificia Universidad Catolica de Chile | N/A |
| Completed | Fluid Balance Neutralization During CRRT (Continuous Renal Replacement Therapy) NCT04801784 | Hospices Civils de Lyon | N/A |
| Withdrawn | Physiological Effects of 38°C vs. 22°C Fluid Therapy in Critically Ill Patients NCT04576806 | Karolinska Institutet | N/A |
| Terminated | Ultrafiltration Therapy Registry Using Aquadex (ULTRA-Peds) NCT04644731 | Nuwellis, Inc. | — |
| Unknown | Bio Electrical Impedance Analysis to Monitor Fluid Status During Deresuscitation Strategy in Continuous Renal NCT05160467 | Hospices Civils de Lyon | — |
| Active Not Recruiting | Prospective, Multi-center, Single-arm, Observational Study. US FDA 522 Pediatric Post Market Surveillance Stud NCT04608149 | Mozarc Medical US LLC | — |
| Completed | Transhepatic Echography for Fluid Responsiveness After Cardiovascular Surgery NCT04914455 | University Hospital, Lille | — |
| Recruiting | Controlled Fluid Removal in Critical Ill Patients With Fluid Overload in the Intensive Care Unit. NCT04180397 | Morten H. Bestle | Phase 4 |
| Completed | Prediction of the Effect of Fluid Administration Using Arterial Pressure and Ventilator Data During Abdominal NCT04298931 | University of Aarhus | — |
| Unknown | End-expiratory Occlusion Test and Lung Recruitment Maneuver to Assess Fluid responsiVeness In Surgical Patient NCT03820440 | Humanitas Clinical and Research Center | N/A |
| Recruiting | The Effect of Fluids on Aortic VTI During C-section NCT04330742 | Baylor College of Medicine | — |
| Completed | Hemodynamic Characteristics of Patients With SARS-CoV-2 NCT04337983 | Bicetre Hospital | — |
| Completed | Effects of Red Blood Cells Transfusion on Renal Blood Flow NCT04194047 | Università degli Studi di Ferrara | — |
| Completed | Point of Care Ultrasound Measurements of Perioperative Edema in Infants With Congenital Heart Disease NCT04151160 | University of Colorado, Denver | — |
| Completed | Discovering the Effect of Venous Insufficiency on Nocturia NCT04266496 | University Hospital, Ghent | N/A |
| Terminated | The Predictive Performance of Renal Ultrasound on Changes in Renal Clearance NCT04198168 | Aarhus University Hospital | — |
| Terminated | Compare the Diuretic Effect With Furosemide vs Furosemide and Albumin Combined in Cirrhotic Patients NCT04216784 | Rush University Medical Center | Phase 4 |
| Terminated | A Feasibility Study on Ultrafiltration and Blood Volume Measurements NCT04241718 | Nuwellis, Inc. | N/A |
| Suspended | Lung Ultrasound-guided Fluid Therapy in Pediatric Intensive Care Unit Patients NCT04215692 | Instituto Mexicano del Seguro Social | N/A |
| Completed | Target Weight Correction and Vascular Stiffness in Hemodialysis Patients NCT03929471 | University of Alberta | N/A |
| Completed | Pathophysiology of Perioperative Fluid Management in Emergency Laparotomy NCT03997721 | Copenhagen University Hospital, Hvidovre | — |
| Completed | Goal Directed Fluid Management , Pvi NCT03956901 | Bakirkoy Dr. Sadi Konuk Research and Training Hospital | N/A |
| Terminated | Diuretic Effect of Metolazone Pre-dosing Versus Concurrent Dosing NCT03746002 | University of Maryland, Baltimore | Phase 4 |
| Completed | Inferior Venacava Ultrasound to Guide Fluid Management for Prevention of Hypotension After Spinal Anesthesia. NCT04736498 | Tribhuvan University, Nepal | N/A |
| Completed | Diastolic Dysfunction and Interstitial Lung Edema in Septic Patients NCT03768752 | Universitätsklinikum Hamburg-Eppendorf | — |
| Terminated | Effects of Restrictive Fluid Strategy on Postoperative Oliguric Pancreatic Surgery Patients NCT03553394 | Uppsala University | N/A |
| Completed | Ultrasound Markers of Organ Congestion in Severe Acute Kidney Injury NCT04095143 | Centre hospitalier de l'Université de Montréal (CHUM) | — |
| Completed | Fluid Balance and Body Weight Changes in Critically Ill Adult Patients NCT04434079 | Hospital de Clinicas de Porto Alegre | — |
| Unknown | Feasibility and Safety in the Management of Fluid Overload in Peritoneal Dialysis Patients Through Sweat Stimu NCT03563898 | Hospital Civil de Guadalajara | N/A |
| Completed | Fluid Absorption in Patients Undergoing Operative Hysteroscopy; Results From a Prospective Controlled Study NCT04328870 | University of Jordan | N/A |
| Unknown | Albumin Mass Balance in Liver Transplantation NCT03441035 | Ake Norberg | — |
| Completed | The Effect of Maintenance Fluids on Overall Fluid Balance in ICU Patients NCT03972475 | Uppsala University | — |
| Unknown | Fluid Status in Valvular Heart Disease NCT03371394 | Medical University of Vienna | — |
| Unknown | Hydratation Status at Initiation of Peritoneal Dialysis: Study of the Role of Peritoneal Permeability NCT03322410 | CHU de Reims | N/A |
| Terminated | The Effect of Vitamin C, Thiamine and Hydrocortisone on Clinical Course and Outcome in Patients With Severe Se NCT03335124 | University Medical Centre Ljubljana | Phase 4 |
| Completed | Influence of Perioperative Fluid Therapy on Hemoglobin and Methemoglobin Levels NCT03220620 | University of Rostock | — |
| Unknown | VolumE maNagement Under Body Composition Monitoring in Critically Ill patientS on CRRT NCT03330626 | Seoul National University Hospital | N/A |
| Unknown | Diagnosis Accuracy of Abdominal Compression and Hemoconcentration to Detect Diuretic Induced Fluid Removal Int NCT03145935 | Hopital Louis Pradel | — |
| Completed | Dialysate Sodium Lowering Trial NCT03144817 | Tufts Medical Center | Phase 2 |
| Completed | TOnicity of Perioperative Maintenance SoluTions NCT03080831 | Niels Van Regenmortel | Phase 4 |
| Completed | Goal-directed Fluid Therapy in Elderly Patients Undergoing Lumbar Surgery NCT03974906 | Peking Union Medical College Hospital | N/A |
| Completed | Does Fluid Requirement Decrease With the Use of Pneumatic Compression Device on Lower Limbs NCT03789474 | All India Institute of Medical Sciences, Rishikesh | N/A |
| Unknown | Diagnosis Accuracy of Hemoconcentration to Detect Hypovolemia During CRRT NCT03144349 | Hopital Louis Pradel | — |
| Completed | Influence of Fluid Challenge on End-Expiratory Lung Impedance in Mechanically Ventilated Patients Monitored Wi NCT02992002 | University Hospital Schleswig-Holstein | — |
| Completed | Predicting Fluid Responsiveness in on Pump Coronary Artery Bypass Graft Using Extra Systoles NCT02903316 | University of Aarhus | — |
| Unknown | Fluid Restriction Keeps Children Dry NCT02989051 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | Phase 2 / Phase 3 |
| Completed | Non-invasive Cardiac Output Monitor in Young Adults NCT02813915 | Indiana University | — |
| Completed | Ultrasound Lung Fluid Responsiveness During Hysterectomy NCT03429751 | Alaa Mazy | N/A |
| Completed | Goal-directed Intraoperative Fluid Therapy in High-risk Surgery NCT02470221 | Huang YuGuang | — |
| Completed | Comparison of PVI-guided Fluid Management With Traditional Fluid Management in Colorectal Surgery NCT03339895 | Kocaeli University | N/A |
| Terminated | Forced Fluid Removal in High Risk Acute Kidney Injury NCT02458157 | Nordsjaellands Hospital | Phase 4 |
| Completed | Evaluating the Fluid Balance of Mechanically Ventilated Patients by Ultrasonography NCT03204292 | Jagiellonian University | — |
| Completed | Fluid Mobilization in Hospitalized Patients With Acute Kidney Injury NCT04522635 | University of California, San Diego | Phase 4 |
| Completed | Impact of Rational Control of Fluid Balance in the Intensive Care Unit NCT02345681 | Nantes University Hospital | Phase 3 |
| Completed | Comparison of Non-Invasive Methods of Assessing Fluid Responsiveness in ED and ICU Patients NCT02679625 | Olive View-UCLA Education & Research Institute | — |
| Completed | Can Vena Cava Ultrasound Guided Volume Repletion Prevent Spinal Induced Significant Hypotension in Elective Pa NCT02271477 | Ente Ospedaliero Cantonale, Bellinzona | N/A |
| Completed | Advanced Hemodynamic Monitoring in Free Flap Surgery NCT03168126 | Universitätsklinikum Hamburg-Eppendorf | — |
| Completed | Application of Bioimpedance Spectroscopy in Taiwan Dialysis Patients NCT02325856 | An Hsin QingShui Clinic | N/A |
| Completed | Body Composition Monitoring(BCM) for Determination of the Fluid Status in Patients Undergoing General Anesthes NCT01945541 | Medical University of Vienna | N/A |
| Completed | Furosemide Versus Ethacrynic Acid in Children With Congenital Heart Disease NCT01628731 | Bambino Gesù Hospital and Research Institute | Phase 3 |
| Terminated | Use of Biomarkers to Optimize Fluid Dosing,CRRT Initiation and Discontinuation in Pediatric ICU Patients With NCT01416298 | Children's Hospital Medical Center, Cincinnati | N/A |
| Completed | The Effect of Crystalloids and Colloids on Visceral Blood Flow NCT01087853 | University of Nottingham | Phase 1 / Phase 2 |
| Completed | Restrictive or Doppler-guided Fluid Treatment in Colorectal Surgery NCT03677622 | Holbaek Sygehus | N/A |
| Completed | The Optimization of Blood Pressure and Fluid Status Control With Eight-Polar Bioelectrical Impedance Analysis NCT00852514 | Taipei Veterans General Hospital, Taiwan | Phase 4 |
| Completed | Crystalloids Versus Colloids During Surgery NCT00517127 | Medical University of Vienna | Phase 4 |
| Withdrawn | "The Effect of Reduced Fluid Load After Cardiac Surgery" NCT01438502 | Haukeland University Hospital | — |