Trials / Unknown
UnknownNCT03144349
Diagnosis Accuracy of Hemoconcentration to Detect Hypovolemia During CRRT
Is Variation of Plasmatic Protein Concentration During Continuous Renal Replacement Therapy Predictive of Hypovolemia in Intensive Care Unit?
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 52 (estimated)
- Sponsor
- Hopital Louis Pradel · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The aim of the study is to analyze if blood protein concentration variation during continuous renal replacement therapy (CRRT) with fluid removal can predict a decrease of 15 % of cardiac index in intensive care unit (ICU) patients. Blood protein concentration, clinical data describing hemodynamic status (providing data from Pulsion medical system PiCCO2 ® monitoring), including preload dependency evaluation with passive leg raising, are collected at different times: before initiation of fluid removal, and after the first episode of hypotension or one hour after initiation of fluid removal.
Detailed description
The aim of the study is to analyze if blood protein concentration variation during continuous renal replacement therapy (CRRT) with fluid removal can predict a decrease of 15 % of cardiac index in intensive care unit (ICU) patients. Blood protein concentration, clinical data describing hemodynamic status (providing data from Pulsion medical system PiCCO2 ® monitoring), including preload dependency evaluation with passive leg raising, are collected at different times: before initiation of fluid removal, and after the first episode of hypotension or one hour after initiation of fluid removal.
Conditions
Timeline
- Start date
- 2016-12-01
- Primary completion
- 2019-12-01
- Completion
- 2019-12-01
- First posted
- 2017-05-08
- Last updated
- 2019-04-16
Locations
2 sites across 1 country: France
Source: ClinicalTrials.gov record NCT03144349. Inclusion in this directory is not an endorsement.