NCT06899880

Perfusion Parameters and Outcome During a Standardized Deresuscitation Strategy with Net Ultrafiltration: a Retrospective Cohort Study.

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 120 (actual)
• Sponsor: Hospices Civils de Lyon · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

Hemodynamic tolerance of fluid removal during deresuscitation is a cornerstone of the impact on outcome of such a strategy. However, how to define and to predict hemodynamic tolerance to fluid removal remains controversial. The investigators routinely use a standardized deresuscitation protocol in patients with fluid overload and continuous renal replacement therapy combined with monitoring of clinical and biological perfusion parameters. The aim of the study was to describe perfusion during deresuscitation, and to determine whether it is associated with major adverse kidney events at day 30.

Conditions

• Fluid Overload
• Acute Kidney Injury
• Continuous Renal Replacement Therapy

Interventions

Type	Name	Description
OTHER	Describe the perfusion parameters during a deresuscitation strategy and their association with the outcome.	Arterial lactate, pCO2 gap, SvO2, capillary refill time and mottling score anomalies will be described during the first 5 days of the deresuscitation strategy.

Timeline

• Start date: 2024-01-01
• Primary completion: 2024-03-01
• Completion: 2024-04-01
• First posted: 2025-03-28
• Last updated: 2025-03-28

Locations

1 site across 1 country: France