Trials / Completed
CompletedNCT04194047
Effects of Red Blood Cells Transfusion on Renal Blood Flow
Effects of Red Blood Cells Transfusion on Renal Resistivity Index and Renal Venous Stasis Index
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 33 (actual)
- Sponsor
- Università degli Studi di Ferrara · Academic / Other
- Sex
- All
- Age
- 18 Years – 90 Years
- Healthy volunteers
- Not accepted
Summary
The renal Doppler resistive index (RRI) is a noninvasive tool that has been used to assess renal perfusion in the intensive care unit (ICU) setting. It is associated with the occurrence of acute kidney injury (AKI). Many parameters have been described as influential on the values of renal RI. Red blood cell (RBC) transfusion were shown to be able to increase renal oxygenation in animal model, whereas crystalloid resuscitation did not. We sought to describe the different effect of crystalloids infusion and RBC transfusion on renal blood flow, as evaluated with doppler ultrasound
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Transfusion | RBC transfusion (1 unit) |
| OTHER | Crystalloids infusion | Infusion of 500 ml of balanced crystalloids |
Timeline
- Start date
- 2020-03-01
- Primary completion
- 2022-09-01
- Completion
- 2022-09-01
- First posted
- 2019-12-11
- Last updated
- 2022-09-13
Locations
1 site across 1 country: Italy
Source: ClinicalTrials.gov record NCT04194047. Inclusion in this directory is not an endorsement.