| Not Yet Recruiting | Cerebellar Research in Ultrasound Stimulation NCT07508696 | KU Leuven | N/A |
| Not Yet Recruiting | Image-Guided DBS Programming NCT07433699 | University of Pennsylvania | Phase 1 |
| Not Yet Recruiting | Transcranial Temporal Interference Stimulation (tTIS) To Modulate Essential Tremor NCT07531238 | Vanessa Fleury | N/A |
| Not Yet Recruiting | Neuromodulation Strategies for Treatment-Resistant Essential Tremor Using Chronos™ DBS NCT07302867 | University of British Columbia | N/A |
| Recruiting | Analysis of Cutaneous Phosphorylated Alpha-Synuclein to Identify Patients at Risk of Progressing From Essentia NCT07428447 | CND Life Sciences | — |
| Recruiting | Investigating Subcortical Contributions to Speech Sequencing in Deep Brain Stimulator Recipients NCT07455760 | Boston University Charles River Campus | N/A |
| Not Yet Recruiting | Magnetoencephalography (MEG) Pilot Study NCT07446192 | University of Florida | N/A |
| Recruiting | Dual-Site Transcranial Magnetic Stimulation of the Supplementary Motor Area and Cerebellum for the Treatment o NCT07344194 | São Paulo State University | Phase 1 / Phase 2 |
| Recruiting | LIFUS For Neurological Disorders NCT07417280 | University Health Network, Toronto | N/A |
| Recruiting | Analysis of Clinical Outcomes in Patients Undergoing Magnetic Resonance-Guided Focused Ultrasound for Medicati NCT07212244 | Sunnybrook Health Sciences Centre | — |
| Recruiting | Attention and Eye Movement in Parkinson's Disease NCT06899022 | University of Nebraska | N/A |
| Recruiting | Proof of Concept Study on BP1.4979 Effect on Essential Tremor NCT07074002 | Bioprojet | Phase 2 |
| Not Yet Recruiting | Developing a New LIFU Neuromodulation Method to Suppress Tremor NCT07103265 | University of Calgary | Phase 2 |
| Recruiting | Simultaneous Bilateral Radiofrequency Thalamotomy for Medication-Refractory Essential Tremor NCT07066358 | Tokyo Women's Medical University | N/A |
| Not Yet Recruiting | GyroGlove Use in Essential Tremor Patients NCT05958030 | GyroGear Ltd | N/A |
| Recruiting | Modulate Tremor Severity With Low-intensity Focused Ultrasound Stimulation Targeting the Deep Nucleus of Patie NCT07172295 | National Taiwan University Hospital | N/A |
| Not Yet Recruiting | Safety and Effectiveness of Unilateral MR-Guided Focused Ultrasound Thalamotomy for Essential Tremor NCT07006740 | meishanshan | — |
| Recruiting | Temporal Interference for Essential Tremor NCT07016425 | Liankun_Ren | N/A |
| Recruiting | Deep Brain Stimulation of the Deep Cerebellar Nuclei for Refractory Tremor NCT07049003 | The Cleveland Clinic | Phase 1 |
| Recruiting | Circadian Adaptive DBS in Essential Tremor NCT06635811 | University of Florida | N/A |
| Recruiting | EMBRACE Tremor BiFUS NCT06974916 | InSightec | N/A |
| Enrolling By Invitation | The Efficacy of Aldehyde Dehydrogenase Enzyme in Essential Tremor Patients: A Single-Center Study NCT07238725 | Pico Entech Co., Ltd. | N/A |
| Active Not Recruiting | Impact of Sensory Electrical Stimulation on Sensation and Tremor NCT06428526 | Shirley Ryan AbilityLab | N/A |
| Recruiting | Home Use Study of Targeted Mechanical Stimulation for Tremor Relief NCT07078422 | Encora, Inc. | N/A |
| Recruiting | Stereotactic Radiosurgery in the Treatment of Essential Tremor NCT06821906 | Maria Sklodowska-Curie National Research Institute of Oncology | Phase 2 |
| Recruiting | Ultrasound Neuromodulation in Essential Tremor NCT06610877 | University of California, San Francisco | N/A |
| Enrolling By Invitation | A Study to Evaluate the Safety and Efficacy of Staged Bilateral Magnetic Resonance-Guided Focused Ultrasound T NCT06676501 | Chinese PLA General Hospital | N/A |
| Completed | Nonlinear Absorber in Essential Tremor Treatment NCT06397391 | Hospices Civils de Lyon | N/A |
| Recruiting | Possibilities of Use MRI-Guided Laser Interstitial Thermal Therapy in Medically Intractable Tremor NCT06799923 | Centre Hospitalier Universitaire, Amiens | N/A |
| Recruiting | 24-months Study to Evaluate Safety and Efficacy of Peroneal Transcutaneous NeuroModulation in Subjects With Pa NCT06570421 | Stimvia s.r.o. | N/A |
| Recruiting | Directional Bilateral Thalamic Patterned Stimulation (Chronos) NCT06325852 | Alfonso Fasano | N/A |
| Recruiting | Tapping Test and the Archimedean Spiral for the Differential Diagnosis of Tremor. Machine Learning Approach NCT06378619 | Consorci Sanitari de l'Alt Penedès i Garraf | — |
| Recruiting | The Effect of Alcohol on Common Tremor Syndromes NCT06403280 | Medical University of Graz | N/A |
| Recruiting | The BRAINMAP-DBS Study: BRain Network AnalysIs usiNg 7-Tesla MRI and MAgnetoencephalograPhy for Deep Brain Sti NCT06932692 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | N/A |
| Not Yet Recruiting | Lesioning Procedures for Movement Disorders NCT06352268 | All India Institute of Medical Sciences | — |
| Enrolling By Invitation | Identifying Markers of Disease Subtypes and Disease Progression in the Syndrome of Essential Tremor NCT06349538 | Medical University of Graz | — |
| Recruiting | Functional Brain Network Changes in Patients Undergoing Deep Brain Stimulation for Essential Tremor NCT06293638 | The Cleveland Clinic | — |
| Recruiting | 3-D Tractography FUS Ablation for Essential Tremor NCT06331052 | University of North Carolina, Chapel Hill | N/A |
| Active Not Recruiting | Assessment of the Safety and Efficacy of the Felix NeuroAI Wristband in Essential Tremor NCT06235190 | Fasikl Inc. | N/A |
| Recruiting | Multicentre RCT of Awake Versus Asleep Tractography Based DBS for ET NCT05968976 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | N/A |
| Recruiting | Radiofrequency (RF) Ablation Prospective Outcomes Study for Central Nervous System - RAPID for CNS NCT06553625 | Boston Scientific Corporation | — |
| Completed | Upper Limb Tremor Reduction in Essential Tremor Patients NCT06343285 | Encora, Inc. | N/A |
| Completed | The Development of a System for Measurement of Tremor NCT05956223 | The Bionics Institute of Australia | N/A |
| Recruiting | Repetitive Transcranial Magnetic Stimulation Therapy in Essential Tremor NCT06145932 | Second Affiliated Hospital of Soochow University | N/A |
| Enrolling By Invitation | Essential 3 - Decentralized, Phase 3 Study Evaluating the Safety and Efficacy of Ulixacaltamide in Essential T NCT06087276 | Praxis Precision Medicines | Phase 3 |
| Completed | Study to Evaluate Safety and Efficacy of Peroneal Transcutaneous NeuroModulation in Subjects With Parkinson's NCT06036368 | Stimvia s.r.o. | N/A |
| Recruiting | Coordinated Reset Deep Brain Stimulation for Essential Tremor NCT05897775 | University of Minnesota | Phase 1 |
| Enrolling By Invitation | A Study of Wearable Device in Essential Tremor Patients NCT05976074 | Mayo Clinic | N/A |
| Recruiting | The STEREO-DBS ET Study: 7-Tesla MRI Brain Network Analysis for Deep Brain Stimulation in Essential Tremor NCT05909839 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | — |
| Completed | Pilot Study of the Felix System in Patients With Essential Tremor and Parkinson's Tremor NCT05842434 | Fasikl Inc. | N/A |
| Unknown | Investigating LFP Correlates of TUS in Patients With Movement Disorders NCT05965960 | University Health Network, Toronto | N/A |
| Recruiting | Electroclinical Correlates in Essential Tremor NCT05671848 | University Hospital, Bordeaux | N/A |
| Withdrawn | New Stereotactic Frame System for Neurosurgery NCT04283812 | Mayo Clinic | N/A |
| Unknown | Echo-Focusing in Patients With Treatment-Resistant Neurologic and Psychiatric Indications (EF001) NCT05089786 | InSightec | N/A |
| Unknown | Bridging Gaps in the Neuroimaging Puzzle: New Ways to Image Brain Anatomy and Function in Health and Disease U NCT05769933 | CSEM Centre Suisse d'Electronique et de Microtechnique SA - Recherche et Developpement | — |
| Completed | Tolerability and Efficacy of Continuous Theta-burst Stimulation for Essential Tremor: A Randomized Study. NCT06314139 | West China Hospital | N/A |
| Unknown | Comparison of the Electric Plasma Surgical Tool "PlasmaBlade" for Replacement of the Deep Brain Stimulation (D NCT05535556 | Yonsei University | — |
| Unknown | Open Label Study for the Use of Transcranial Ultrasound Treatment of Tremor NCT05475340 | Neurological Associates of West Los Angeles | EARLY_Phase 1 |
| Terminated | A Study to Evaluate the Long-term Safety and Tolerability of SAGE-324 in Participants With Essential Tremor NCT05366751 | Sage Therapeutics | Phase 2 / Phase 3 |
| Recruiting | Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia NCT05317390 | Massachusetts Eye and Ear Infirmary | N/A |
| Unknown | Neurophysiologic Assessment of ET Patients Treated by Vim DBS NCT05362448 | University College London Hospitals | N/A |
| Withdrawn | A Clinical Trial of PRAX-114 in Participants With Essential Tremor NCT05387642 | Praxis Precision Medicines | Phase 2 |
| Completed | JAME, a Wearable Device to Control Tremor NCT06847581 | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | N/A |
| Terminated | Impact of a Standardized Music Therapy Protocol on the Quality of Life of Patients With Abnormal Movements Tre NCT05214313 | University Hospital, Montpellier | N/A |
| Unknown | Clinical Profile in Patients With Essential Tremors NCT05170022 | Assiut University | — |
| Recruiting | Motor Network Physiology NCT04957095 | University of Texas Southwestern Medical Center | N/A |
| Completed | Study to Evaluate SAGE-324 in Participants With Essential Tremor NCT05173012 | Sage Therapeutics | Phase 2 |
| Completed | Repetitive Transcranial Magnetic Stimulation in Essential Tremors Patients NCT05157321 | Al-Azhar University | N/A |
| Completed | A Study To Assess the Safety and Efficacy of JZP385 in the Treatment of Adults With Moderate to Severe Essenti NCT05122650 | Jazz Pharmaceuticals | Phase 2 |
| Recruiting | Elucidating the Temporality of Structural and Functional Connectivity Changes in Essential Tremor After Succes NCT04758624 | Northwell Health | N/A |
| Completed | Interphase Gap in Biphasic Stimulation in DBS for ET NCT05177900 | Myles Mc Laughlin | N/A |
| Completed | [18F] LBT-999 PET Compared to [123I]-FP/CIT SPECT to Distinguish Between Parkinson's Diseases and Essential Tr NCT04265209 | GE Healthcare | Phase 3 |
| Terminated | DBS of Posterior Subthalamic Area (PSA) and Ventral Intermediate Nucleus (VIM) in Essential Tremor (ET) NCT05096572 | St. Joseph's Hospital and Medical Center, Phoenix | N/A |
| Completed | A Clinical Trial of 2 Doses of PRAX-944 in Participants With Essential Tremor NCT05021991 | Praxis Precision Medicines | Phase 2 |
| Completed | The Effects of Vibrotactile Stimulation in Patients With Movement Disorders NCT05106816 | University of Florida | N/A |
| Completed | Symptomatic Relief of Action Tremor With Cala Trio Using Trio+ Bands NCT05480215 | Cala Health, Inc. | N/A |
| Recruiting | Neurofeedback Using Implanted Deep Brain Stimulation Electrodes NCT05101161 | ETH Zurich | N/A |
| Withdrawn | VIM DBS Respiratory Modulation: N-of-1 Trial NCT05381688 | University of Oxford | — |
| Active Not Recruiting | Linac FRACtionated Radiosurgical THALamotomie in Tremors (FRACTHAL) NCT04727658 | Centre Hospitalier Universitaire de Nice | Phase 2 |
| Terminated | directSTIM™ Deep Brain Stimulation System Post-Market Clinical Follow-up Study on Essential Tremor NCT05795218 | Aleva Neurotherapeutics SA | — |
| Recruiting | Bilateral Essential Tremor Treatment With Gamma Knife NCT04748640 | Université de Sherbrooke | Phase 2 / Phase 3 |
| Completed | Safety, Efficacy, and Tolerability of NBI-827104 for the Treatment of Essential Tremor NCT04880616 | Neurocrine Biosciences | Phase 2 |
| Completed | Analysis and Suppression of Tremor During Grasp Using Ultrasound Imaging and Electrical Stimulation NCT05308368 | North Carolina State University | N/A |
| Completed | RWE Study Utilizing the Cala Trio Device in Patients With Essential Tremor NCT05540626 | Cala Health, Inc. | N/A |
| Completed | Physiology, Imaging and Modeling of Essential Tremor NCT03811405 | University of Florida | N/A |
| Recruiting | Directional Versus Nondirectional DBS for ET NCT04828798 | Oregon Health and Science University | N/A |
| Completed | Complex Eye Movements in Parkinson's Disease and Related Movement Disorders NCT04925622 | Saccadous, Inc. | — |
| Completed | Characterization of Complex Pulse Shapes in Deep Brain Stimulation for Movement Disorders Using EEG and Local NCT04658641 | KU Leuven | N/A |
| Completed | Deep Brain Stimulation Effects in Essential Tremor NCT04581941 | University of Florida | — |
| Completed | Brain Networks and Consciousness NCT04502550 | University of Texas Southwestern Medical Center | — |
| Completed | A Second Magnetic Resonance Guided Focused Ultrasound Thalamotomy for Essential Tremor NCT04720469 | Sunnybrook Health Sciences Centre | N/A |
| Unknown | Alternating Current Stimulation for Essential Tremor NCT04509349 | University of Calgary | N/A |
| Recruiting | Cortical-Basal Ganglia Speech Networks NCT04286308 | Massachusetts General Hospital | N/A |
| Recruiting | Sensory-specific Peripheral Stimulation for Tremor Management NCT04501133 | Shirley Ryan AbilityLab | N/A |
| Active Not Recruiting | Bilateral Essential Tremor Treatment With FUS NCT04501484 | University Health Network, Toronto | N/A |
| Completed | Environmental Epidemiology of Essential Tremor NCT04576676 | University of Texas Southwestern Medical Center | — |
| Active Not Recruiting | Bilateral Treatment of Medication Refractory Essential Tremor NCT04112381 | InSightec | N/A |
| Completed | A Study to Evaluate the Diagnostic Efficacy of DaTSCAN™ Ioflupane (123I) Injection in Single Photon Emission C NCT04193527 | GE Healthcare | Phase 3 |
| Completed | A Study to Evaluate the Efficacy, Safety, and Tolerability of SAGE-324 in Participants With Essential Tremor NCT04305275 | Sage Therapeutics | Phase 2 |
| Completed | The Relationship of Muscle Strength With Functional Skills in Geriatric Individuals With Essential Tremor NCT05244863 | Kahramanmaras Sutcu Imam University | — |
| Completed | A Clinical Trial of PRAX-944 in Participants With Essential Tremor NCT05021978 | Praxis Precision Medicines | Phase 2 |
| Unknown | Cyclic Deep Brain Stimulation in Essential Tremor NCT04260971 | King's College Hospital NHS Trust | N/A |
| Completed | Modulatory Effects of Deep Brain Stimulation on Cerebral Cortical Activity NCT04361955 | The Cleveland Clinic | N/A |
| Unknown | Transcranial Ultrasound Therapy of Essential Tremor NCT04074031 | Assistance Publique - Hôpitaux de Paris | N/A |
| Recruiting | Dual Lead Thalamic Deep Brain Recording (DBR)-DBS Interface for Closed Loop Control of Severe Essential Tremor NCT04212780 | University of Florida | N/A |
| Recruiting | Abbott DBS Post-Market Study of Outcomes for Indications Over Time NCT04071847 | Abbott Medical Devices | — |
| Recruiting | Boston Scientific Registry of Deep Brain Stimulation for Treatment of Essential Tremor (ET) NCT04032470 | Boston Scientific Corporation | — |
| Recruiting | Algorithms for Programming DBS Systems for ET NCT03984643 | University of Minnesota | N/A |
| Unknown | Transcranial Direct Current Stimulation of the Motor Cortex in Essential Tremor NCT03952117 | Lebanese American University | N/A |
| Unknown | Using Wearable and Mobile Data to Diagnose and Monitor Movement Disorders NCT04231487 | Rutgers, The State University of New Jersey | — |
| Completed | Evaluation of the Infinity Deep Brain Stimulation Electrode Screening Mode Tool NCT03794661 | Abbott Medical Devices | N/A |
| Completed | A Post-Market Study Evaluating the Safety of Infinity DBS System With MR Conditional Labeling NCT03884231 | Abbott Medical Devices | — |
| Completed | Next-Generation Pre-Operative Targeting for Thalamic DBS in the Treatment of Tremor NCT03875404 | Mayo Clinic | N/A |
| Completed | Optimization of VIM Targeting in Essential Tremor Surgery NCT03760406 | University Hospital, Bordeaux | N/A |
| Recruiting | Deep Brain Stimulation (DBS) Retrospective Outcomes Study NCT03664609 | Boston Scientific Corporation | — |
| Unknown | Brain Network Activation in Patients With Movement Disorders NCT03269201 | Sheba Medical Center | — |
| Completed | Investigating the Use of Complex Pulse Shapes for DBS in Movement Disorders NCT04725045 | KU Leuven | N/A |
| Active Not Recruiting | Long-Term Transcutaneous Stimulation and Essential Tremor: A PET Study NCT03778060 | Mayo Clinic | N/A |
| Completed | A Clinical Study to Evaluate CAD-1883 in Essential Tremor NCT03688685 | Cadent Therapeutics | Phase 2 |
| Completed | Trial of Cannabis for Essential Tremor NCT03805750 | University of California, San Diego | Phase 1 / Phase 2 |
| Completed | Utilizing Smart Devices to Identify New Phenotypical Characteristics in Movement Disorders NCT03638479 | Universität Münster | — |
| Completed | Staged Bilateral Exablate Treatment of Medication Refractory Essential Tremor NCT03465761 | InSightec | N/A |
| Recruiting | Chinese ET Registry (CETR) NCT04198246 | Xiangya Hospital of Central South University | — |
| Completed | Prospective Study for Symptomatic Relief of ET With Cala Therapy NCT03597100 | Cala Health, Inc. | N/A |
| Terminated | Ataxia in Essential Tremor: Describing the Differences Between Disease Process and Treatment Effect NCT03769961 | Oregon Health and Science University | — |
| Completed | Probabilistic Targeting of the VIM NCT03696420 | University Hospital, Bordeaux | — |
| Completed | tSMS in Essential Tremor NCT03780426 | Fundación de investigación HM | Phase 2 |
| Completed | Wearable Sensor for Responsive DBS for ET NCT03051178 | University of Florida | N/A |
| Unknown | Relief From Side Effects: Clinical Use of Electrodes With Direction NCT03795935 | University of British Columbia | N/A |
| Active Not Recruiting | Functional Neuroimaging Feedback for Focused Ultrasound Thalamotomy NCT03560622 | Vibhor Krishna | N/A |
| Terminated | Essential Tremor in Children and Adolescent NCT03487705 | University Hospital, Montpellier | N/A |
| Recruiting | The Swedish Essential Tremor (SWEET) Trial NCT03832712 | Karolinska Institutet | N/A |
| Active Not Recruiting | RAD 1601: EDGE Radiosurgery for Intractable Essential Tremor and Tremor-Dominant Parkinson's Disease NCT03305588 | University of Alabama at Birmingham | N/A |
| Withdrawn | Efficacy of Pramipexole Extended Release in the Treatment of Essential Tremor NCT01441284 | University of Pecs | Phase 3 |
| Completed | A Phase 2 RCT Study of CX-8998 for Essential Tremor NCT03101241 | Jazz Pharmaceuticals | Phase 2 |
| Completed | Pathophysiology of Tremor-modulating Mechanisms of Propranolol and Primidone in Essential Tremor NCT04692844 | University Medical Centre Ljubljana | — |
| Completed | A Pilot Study of the Cala ONE Device for Essential Tremor NCT03152136 | Cala Health, Inc. | N/A |
| Completed | Clinical and Physiological Studies of Tremor Syndromes NCT03027310 | National Institute of Neurological Disorders and Stroke (NINDS) | — |
| Completed | Neurophysiologic Study of Patient With Essential Tremor and Dystonic Tremor NCT03041714 | National Institute of Neurological Disorders and Stroke (NINDS) | — |
| Completed | A Study to Evaluate SAGE-217 in Participants With Essential Tremor NCT02978781 | Biogen | Phase 2 |
| Active Not Recruiting | Responsive Deep Brain Stimulator for Essential Tremor NCT02649166 | University of Florida | N/A |
| Active Not Recruiting | Global Registry: ExAblate Neuro MR Guided Focused Ultrasound (MRgFUS) of Neurological Disorders: NCT03100474 | InSightec | — |
| Completed | The Effectiveness of Alternating Stimulation in Preventing Tolerance in Essential Tremor Patients NCT02947841 | Oregon Health and Science University | N/A |
| Terminated | Atlas Predicted DBS Settings in Essential Tremor NCT02678429 | Vanderbilt University | N/A |
| Terminated | Evaluation of Directional Recording and Stimulation Using spiderSTN NCT02894567 | Aleva Neurotherapeutics SA | N/A |
| Completed | Deep Brain Stimulation for Voice Tremor: Left, Right, or Both Hemispheres? NCT02960243 | University of British Columbia | N/A |
| Completed | Comparison of Botulinum Toxin Injections in Forearm FLexor Plus EXtensor Muscles vs. Flexor Muscles Alone for NCT02909907 | The Cleveland Clinic | N/A |
| Enrolling By Invitation | Effects of Stimulation Patterns of Deep Brain Stimulation NCT02553525 | Duke University | N/A |
| Completed | Biomarkers in Neural Disorders NCT02761707 | University of Pennsylvania | — |
| Completed | Cala ONE Device for Essential Tremor NCT02629614 | Cala Health, Inc. | N/A |
| Completed | Cerebellar rTMS for Essential Tremor NCT02704793 | Mashhad University of Medical Sciences | N/A |
| Completed | The Motor Network in Essential Tremor: Mechanisms of Therapy NCT02712515 | University of Florida | — |
| Withdrawn | Acamprosate and Methazolamide for Essential Tremor NCT06312800 | Henry Ford Health System | Phase 2 |
| Unknown | Mapping Functional Networks of Brain Activity Using EEG in Patients With Essential Tremor or Parkinson Disease NCT02692183 | Sheba Medical Center | — |
| Completed | Essential Voice Tremor: A Study of Botulinum Toxin Treatment and Injection Augmentation NCT02711995 | Weill Medical College of Cornell University | N/A |
| Completed | GADGET-PD Genetic and Digital Diagnosis of Essential Tremor and Parkinson's Disease Trial NCT02668835 | Scripps Translational Science Institute | — |
| Unknown | An Efficacy/Safety Study of Perampanel for Reducing Essential Tremor NCT02668146 | VA Greater Los Angeles Healthcare System | Phase 2 |
| Completed | Tremor Monitoring Device NCT02523807 | Rambam Health Care Campus | — |
| Unknown | Deep braIn Stimulation for Tremor TractographIC Versus Traditional NCT02491554 | University Hospital Freiburg | N/A |
| Active Not Recruiting | ExAblate Transcranial MRgFUS for the Management of Treatment-Refractory Movement Disorders NCT02252380 | InSightec | N/A |
| Completed | Continued Access Protocol: ExAblate Transcranial MR Guided Focused Ultrasound for the Treatment of Essential T NCT02289560 | InSightec | N/A |
| Completed | Cerebello-thalamo-cortical Coupling in Essential Tremor NCT02346409 | Institut National de la Santé Et de la Recherche Médicale, France | N/A |
| Terminated | Transcranial Stimulation for Essential Tremor NCT03025529 | Beth Israel Deaconess Medical Center | N/A |
| Completed | Demand-driven Management of Essential Tremor NCT02443181 | University of Washington | N/A |
| Withdrawn | Functional Outcomes of Awake vs. Asleep Deep Brain Stimulation (DBS) for Essential Tremor NCT02418858 | St. Joseph's Hospital and Medical Center, Phoenix | N/A |
| Enrolling By Invitation | Sensory Gating Measured With Microelectrode Recording (MER) During Deep Brain Stimulation (DBS) Surgery NCT02320266 | University of Colorado, Denver | — |
| Terminated | A Study to Evaluate the Effectiveness and Safety of ExAblate MRgFUS on Essential Tremor NCT03253991 | InSightec | N/A |
| Completed | Thalamic LFPs and VIM DBS in Essential Tremor: Correlation, Evolution, and Therapeutic Perspectives NCT02264925 | University Hospital, Bordeaux | N/A |
| Completed | Limb Cooling in Essential Tremor NCT02067702 | University of Florida | — |
| Completed | Evaluate SAGE-547 in Participants With Essential Tremor NCT02277106 | Sage Therapeutics | Phase 2 |
| Unknown | Gamma Knife Radiosurgery for Treatment of Essential Tremor NCT02255929 | Swedish Medical Center | N/A |
| Unknown | Kinematic-based BoNT-A Injections for Bilateral ET NCT02551848 | Western University, Canada | Phase 2 |
| Completed | A Pilot Study to Assess the Effects of Pre-SMA LF-rTMS for the Treatment of Essential Tremor NCT02763865 | Medical University of South Carolina | N/A |
| Completed | Experimental Therapeutics in Essential Tremor Using Cerebellar Transcranial Direct Current Stimulation NCT02052271 | Institut National de la Santé Et de la Recherche Médicale, France | N/A |
| Completed | Propranolol and Botulinum Toxin for Essential Vocal Tremor NCT02111369 | Emory University | Phase 4 |
| Completed | Battery-preserving Stimulation Patterns for Deep Brain Stimulation NCT02569021 | University of Florida | — |
| Completed | Local Fields Potentials Recorded From Deep Brain Stimulating Electrodes NCT02071446 | University of Colorado, Denver | — |
| Completed | Functional Imaging of Tremor Circuits and Mechanisms of Treatment Response NCT02495883 | University of California, San Diego | Phase 4 |
| Completed | Defining Phenotypes of Movement Disorders :Parkinson's Plus Disorders (PD), Essential Tremor (ET), Cortical Ba NCT02132052 | University of Colorado, Denver | — |
| Completed | Montreal Cognitive Assessment Index Following MRI Guided Focused Ultrasound Thalamotomy NCT06941285 | Rambam Health Care Campus | — |
| Withdrawn | The Essential Tremor (ET) and Parkinson Disease (PD) Tremor Acute Stimulation Study NCT01940406 | BlueWind Medical | N/A |
| Completed | Continuous Tremor Assessment During Daily Activities NCT01978080 | Great Lakes NeuroTechnologies Inc. | N/A |
| Completed | Compare Rates of Agreement Between Clinical Diagnosis and Visual Assessment of DaTscan™ Images in Non-Caucasia NCT01952678 | GE Healthcare | — |
| Completed | ExAblate Transcranial MR Guided Focused Ultrasound for the Treatment of Essential Tremors NCT01827904 | InSightec | N/A |
| Unknown | Deep Brain Stimulation (DBS) Data Base Study NCT01909531 | St. Joseph's Hospital and Medical Center, Phoenix | — |
| Withdrawn | Optimizing DBS Electrode Placement and Programming NCT01820390 | University of Colorado, Denver | — |
| Completed | Functional Magnetic Resonance Imaging (fMRI) During Deep Brain Stimulation (DBS) to Treat Parkinson's Disease NCT01809613 | Mayo Clinic | — |
| Recruiting | Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor NCT01734122 | Vanderbilt University Medical Center | — |
| Completed | Evaluation of Directional Stimulation During the Implantation of Deep Brain Stimulation (DBS) Leads NCT01764815 | Aleva Neurotherapeutics SA | N/A |
| Completed | Magnetic Resonance (MR) Guided Functional Ultrasound-Neurosurgery for Movement Disorders NCT01698450 | University Children's Hospital, Zurich | Phase 1 |
| Unknown | Imaging in the Diagnosis of Parkinson's Disease and Essential Tremor NCT01446939 | Hospital Israelita Albert Einstein | — |
| Completed | Adaptive Portable Essential Tremor Monitor NCT01602042 | Great Lakes NeuroTechnologies Inc. | — |
| Completed | Experimental Therapeutics in Essential Tremor Using Transcranial Direct Current Stimulation NCT01579435 | Institut National de la Santé Et de la Recherche Médicale, France | N/A |
| Completed | Movement Disorder Quantification Algorithm Development NCT01534650 | Great Lakes NeuroTechnologies Inc. | — |
| Completed | Octanoic Acid for Essential Tremor NCT01468948 | National Institute of Neurological Disorders and Stroke (NINDS) | Phase 1 |
| Recruiting | Deep Brain Stimulation Surgery for Movement Disorders NCT01581580 | National Institute of Neurological Disorders and Stroke (NINDS) | N/A |
| Completed | ExAblate (Magnetic Resonance-guided Focused Ultrasound Surgery) for Treatment of Tremor NCT01932463 | InSightec | N/A |
| Completed | A Pilot Efficacy and Safety Study of ST101 in Essential Tremor NCT01332695 | Sonexa Therapeutics, Inc. | Phase 2 |
| Completed | ExAblate Transcranial MR Guided Focused Ultrasound in the Treatment of Essential Tremor NCT02037217 | InSightec | Phase 1 |
| Recruiting | Clinical Outcomes for Deep Brain Stimulation NCT03992625 | Washington University School of Medicine | — |
| Completed | ExAblate Transcranial MR Guided Focused Ultrasound in the Treatment of Essential Tremor NCT01304758 | InSightec | Phase 1 |
| Completed | Decision-making and Emotion Recognition in Essential Tremor NCT01223144 | University Hospital, Bordeaux | N/A |
| Completed | Ethanol Response in Essential Tremor: Clinical and Neurophysiological Correlates NCT01200966 | National Institute of Neurological Disorders and Stroke (NINDS) | — |
| Completed | Neurotransmitter Measurements Using (WINCS) During Deep Brain Stimulation Neurosurgery NCT01705301 | Mayo Clinic | — |
| Completed | RECHARGE Sub-Study to the Implantable Systems Performance Registry (ISPR) NCT00998660 | MedtronicNeuro | Phase 4 |
| Completed | Double-Blind, Placebo Controlled Pilot Study of Octanoic Acid in Essential Tremor NCT00848172 | National Institute of Neurological Disorders and Stroke (NINDS) | Phase 1 / Phase 2 |
| Withdrawn | Pre-lemniscal Radiation Deep Brain Stimulation for ET NCT00634478 | Medical College of Wisconsin | N/A |
| Withdrawn | Dexmedetomidine Effects on Microelectrode Recording in Deep Brain Stimulation NCT00608231 | Vanderbilt University | Phase 2 / Phase 3 |
| Completed | Pregabalin (Lyrica) for the Treatment of Essential Tremor NCT00584376 | University of South Florida | Phase 4 |
| Completed | Multiple-dose,Double-blind,Placebo-controlled Study of Sodium Oxybate in Patients With Essential Tremor NCT00598078 | Jazz Pharmaceuticals | Phase 2 |
| Terminated | WiiMote Game Controller as a Device to Study Movement Disorders NCT00802191 | Vanderbilt University | — |
| Terminated | T2000 in Essential Tremor - Open Label Continuation NCT00655278 | Sun Pharmaceutical Industries, Inc. | Phase 2 |
| Completed | A Pilot Clinical Trial Of Memantine for Essential Tremor NCT00439699 | VA Greater Los Angeles Healthcare System | Phase 4 |
| Completed | Ventrointermediate Nucleus (VIM DBS) and Working Memory NCT00906412 | Washington University School of Medicine | — |
| Completed | Transcranial Duplex Scanning and Single Photon Emission Computer Tomography (SPECT) in Parkinsonian Syndromes NCT00368199 | Maastricht University Medical Center | — |
| Terminated | A Study of T2000 in Essential Tremor NCT00321087 | Sun Pharmaceutical Industries, Inc. | Phase 2 |
| Recruiting | Physiological Brain Atlas Development NCT00575081 | Vanderbilt University Medical Center | — |
| Completed | Pregabalin in the Treatment of Essential Tremor NCT00646451 | Baylor College of Medicine | EARLY_Phase 1 |
| Completed | Deep Brain Stimulation (DBS) for the Suppression of Tremor NCT02087046 | Abbott Medical Devices | N/A |
| Completed | Clinical Trial Characterizing the Bioavailability of 1-Octanol in Adults With Ethanol-responsive Essential Tre NCT00102596 | National Institute of Neurological Disorders and Stroke (NINDS) | Phase 2 |
| Completed | Efficacy of Levetiracetam in Essential Tremor NCT00620165 | Southern California Institute for Research and Education | Phase 1 / Phase 2 |
| Completed | A Safety/Efficacy Trial of Zonisamide for Essential Tremor NCT00223743 | VA Greater Los Angeles Healthcare System | Phase 2 |
| Completed | Octanol to Treat Essential Tremor NCT00080366 | National Institute of Neurological Disorders and Stroke (NINDS) | Phase 2 |
| Completed | Motor-related Cortical Potential in Patients With Essential Tremor NCT01250067 | China Medical University Hospital | N/A |
| Terminated | Zonisamide in the Treatment of Essential Tremor NCT00616343 | Loma Linda University | N/A |
| Completed | Chronic Versus Intermittent Deep Brain Stimulation for Essential Tremor NCT01334814 | Mayo Clinic | N/A |
| Completed | A Comparison of the Efficacy and Safety of Topiramate Versus Placebo in Treating Tremor of Unknown Cause. NCT00236496 | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | Phase 3 |
| Completed | 1-Octanol to Treat Essential Tremor NCT00016679 | National Institute of Neurological Disorders and Stroke (NINDS) | Phase 1 |
| Completed | Novel Therapies for Essential Tremor NCT00018564 | US Department of Veterans Affairs | Phase 3 |
| Completed | 1-Octanol to Treat Essential Tremor NCT00001986 | National Institute of Neurological Disorders and Stroke (NINDS) | Phase 1 |