NCT07016425

Temporal Interference for Essential Tremor

Efficacy and Safety of Non-invasive Temporal Interference Stimulation in the Treatment of Essential Tremor: A Pilot Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (estimated)
• Sponsor: Liankun_Ren · Academic / Other
• Sex: All
• Age: 30 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

This single-center prospective study aims to investigate the treatment efficacy of temporal interference (TI) in essential tremor patients aged 30-70.

Detailed description

Temporal Interference (TI) technology is a novel non-invasive method for deep brain stimulation (DBS). By generating an overlapping electric field from safe currents, TI creates focused stimulation in targeted deep brain areas. This approach allows for the exploration of deep brain nuclei functions and has the potential to serve as a non-invasive alternative to traditional invasive DBS for clinical treatments. This study aims to investigate the treatment efficacy of TI deep brain stimulation by including essential tremor patients aged 30-70. Before and after TI stimulation, clinical data will be recorded. Clinical and imaging data will be analyzed and processed to advance the treatment of essential tremor.

Conditions

• Essential Tremor

Interventions

Type	Name	Description
OTHER	Temporal Interference	Researchers apply temporal interference (TI) stimulation to the deep brain nuclei of essential tremor patients.

Timeline

• Start date: 2025-06-09
• Primary completion: 2026-05-30
• Completion: 2026-09-30
• First posted: 2025-06-11
• Last updated: 2025-07-16

Locations

1 site across 1 country: China