NCT04286308

Cortical-Basal Ganglia Speech Networks

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (estimated)
• Sponsor: Massachusetts General Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

In this research study the researchers want to learn more about brain activity related to speech perception and production.

Detailed description

Speech production is disrupted in a number of neurological diseases that involve the basal ganglia, including Parkinson's disease (PD) and dystonia. The investigators will use a novel experimental approach and combination of analytic techniques to elucidate the contribution of neural activity in cortical-basal ganglia circuits to the hierarchical control of speech production, in subjects undergoing deep brain stimulation surgery.

Conditions

• Parkinson Disease
• Essential Tremor
• Dystonia

Interventions

Type	Name	Description
OTHER	electrophysiological data collection	Electrophysiological data collection at the time of DBS surgery.

Timeline

• Start date: 2020-10-01
• Primary completion: 2027-02-01
• Completion: 2027-02-01
• First posted: 2020-02-27
• Last updated: 2026-03-25

Locations

1 site across 1 country: United States