| Not Yet Recruiting | Validity and Reliability of the Hypertonia Assessment Tool (HAT) in Stroke Patients NCT07429383 | Fatih Sultan Mehmet Training and Research Hospital | — |
| Recruiting | A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia NCT07304089 | Vima Therapeutics | Phase 2 |
| Recruiting | LIFUS For Neurological Disorders NCT07417280 | University Health Network, Toronto | N/A |
| Recruiting | Local Field Potentials in Dystonia NCT07309133 | Newcastle-upon-Tyne Hospitals NHS Trust | — |
| Recruiting | Predicting DBS Outcomes in Dystonia Using Wearable Gait Sensors NCT07323602 | Ruijin Hospital | — |
| Not Yet Recruiting | Long-read Genome Sequencing for the Molecular Diagnosis of Dystonia NCT06999096 | University Hospital, Strasbourg, France | N/A |
| Enrolling By Invitation | Deep Brain Stimulation (DBS) MatchMaker NCT06912841 | Boston Children's Hospital | — |
| Recruiting | Pharmacogenomic Contributions to Trihexyphenidyl Biotransformation and Response in Children With Dystonic Cere NCT06554288 | Children's Mercy Hospital Kansas City | Phase 1 |
| Recruiting | Deep Anterior Cerebellar Stimulation in Treatment of Poststroke Spasticity and Motor Function Impairment. NCT07190092 | Jan Biziel University Hospital No 2 in Bydgoszcz | N/A |
| Recruiting | Chronic Outcome Monitoring for DBS in Dystonia NCT07244549 | Charite University, Berlin, Germany | — |
| Completed | Prospective Pilot Trial to Address Feasibility and Safety of Oral Zinc in GNAO1 Associated Disorders NCT06412653 | Children's University Hospital Cologne, Germany | Phase 2 |
| Recruiting | A Multicenter Pediatric Deep Brain Stimulation Registry NCT06585618 | Boston Children's Hospital | — |
| Unknown | Strategy to Adapt Botulinum Toxin Doses in Dystonia NCT06386848 | Central Hospital, Nancy, France | — |
| Recruiting | The Effect of Alcohol on Common Tremor Syndromes NCT06403280 | Medical University of Graz | N/A |
| Not Yet Recruiting | Lesioning Procedures for Movement Disorders NCT06352268 | All India Institute of Medical Sciences | — |
| Recruiting | The Use of the CUE1/CUE1+ in People With Parkinson's Disease and Related Disorders NCT06174948 | Queen Mary University of London | N/A |
| Recruiting | Differences in Brain Network Mechanisms Between STN and GPi Deep Brain Stimulation in the Treatment of Cranioc NCT06480188 | Anhui Provincial Hospital | N/A |
| Recruiting | Radiofrequency (RF) Ablation Prospective Outcomes Study for Central Nervous System - RAPID for CNS NCT06553625 | Boston Scientific Corporation | — |
| Completed | Study of Behavioral Dysfunctions and Related Neuronal Correlates in Patients With Dystonia NCT06264063 | IRCCS Centro Neurolesi Bonino Pulejo | N/A |
| Recruiting | Quantifying Motor Network Dynamics to Predict and Enhance Outcomes in Pediatric Dystonia NCT07325175 | Children's Hospital Medical Center, Cincinnati | N/A |
| Recruiting | Multimodal Investigation of Cortico-Basal Ganglia-Thalamo-Cortical Network Dynamics in Dystonic Patients With NCT06716983 | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | — |
| Completed | The Development of a System for Measurement of Tremor NCT05956223 | The Bionics Institute of Australia | N/A |
| Not Yet Recruiting | Efficacy and Safety of Radiofrequency Pallidotomy in the Management of Dystonia NCT06038097 | All India Institute of Medical Sciences | N/A |
| Completed | Single and Multiple Ascending Dose Study of MTR-601 in Healthy Individuals NCT06117020 | Motric Bio | Phase 1 |
| Active Not Recruiting | Towards Noninvasive DBS of the Basal Ganglia in Parkinson's Disease Using TUS NCT06232629 | University Health Network, Toronto | N/A |
| Recruiting | Sleep-specific DBS Therapy in Parkinson's Disease NCT05962489 | University of Minnesota | N/A |
| Unknown | Investigating LFP Correlates of TUS in Patients With Movement Disorders NCT05965960 | University Health Network, Toronto | N/A |
| Not Yet Recruiting | Enhancing Sensorimotor Processing in Children With Dystonia NCT05612464 | King's College London | — |
| Withdrawn | New Stereotactic Frame System for Neurosurgery NCT04283812 | Mayo Clinic | N/A |
| Recruiting | Observational Study on "Functional Overlay" in Patients With Movement Disorders NCT05943652 | Medical University of Graz | — |
| Unknown | Sensorimotor Integration in Monogenic Parkinson-dystonia Syndromes NCT05713721 | University Hospital Schleswig-Holstein | — |
| Active Not Recruiting | Harmonic Ratio in Patients With GLUT1 Deficiency Syndrome NCT05887739 | IRCCS National Neurological Institute "C. Mondino" Foundation | — |
| Recruiting | Effects of Exercise on Dystonia Pathophysiology NCT05663840 | University of Florida | N/A |
| Unknown | Comparison of the Electric Plasma Surgical Tool "PlasmaBlade" for Replacement of the Deep Brain Stimulation (D NCT05535556 | Yonsei University | — |
| Recruiting | Deep Brain Stimulation in Laryngeal Dystonia and Voice Tremor NCT05150093 | Massachusetts Eye and Ear Infirmary | N/A |
| Recruiting | Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia NCT05317390 | Massachusetts Eye and Ear Infirmary | N/A |
| Terminated | Impact of a Standardized Music Therapy Protocol on the Quality of Life of Patients With Abnormal Movements Tre NCT05214313 | University Hospital, Montpellier | N/A |
| Withdrawn | Role of Basal Ganglia and Thalamus in Perceptual Consciousness and Metacognition NCT04461730 | University Hospital, Grenoble | — |
| Recruiting | Dystonia Image-based Programming of Stimulation: A Prospective, Randomized, Double-blind Crossover Trial NCT05097001 | Wuerzburg University Hospital | N/A |
| Completed | The Effects of Vibrotactile Stimulation in Patients With Movement Disorders NCT05106816 | University of Florida | N/A |
| Completed | Exploratory Study of Dipraglurant (ADX48621) for the Treatment of Patients With Blepharospasm NCT05027997 | Addex Pharma S.A. | Phase 2 |
| Unknown | Brain Sensing in Neurological and Psychiatric Disorders NCT04810325 | University College, London | — |
| Recruiting | Register for Patients With Thyroid Hormone Resistance. NCT06566066 | Charite University, Berlin, Germany | — |
| Completed | Physiology, Imaging and Modeling of Essential Tremor NCT03811405 | University of Florida | N/A |
| Completed | In Vivo Measurement of the Accuracy of the "Neurolocate" Module of the Neurosurgical Robot "Neuromate" in Its NCT04712552 | Centre Hospitalier Universitaire de Nice | — |
| Unknown | SUNDYS: A Multicenter, Randomized, Double-blind, Sham-controlled, Parallel-group Trial NCT04650958 | Ruijin Hospital | N/A |
| Withdrawn | Neurophysiological Characteristics of Subthalamic Deep-brain Stimulation (STN-DBS) NCT04707638 | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | — |
| Completed | Deep Brain Stimulation Effects in Dystonia NCT04568681 | University of Florida | — |
| Recruiting | Cortical-Basal Ganglia Speech Networks NCT04286308 | Massachusetts General Hospital | N/A |
| Completed | Repetitive Transcranial Magnetic Stimulation (rTMS) for Dystonia and Tremor NCT04299087 | University of Florida | N/A |
| Unknown | Using DBS to Probe Basal Ganglia Dysfunction NCT04080674 | University of Oxford | — |
| Recruiting | Abbott DBS Post-Market Study of Outcomes for Indications Over Time NCT04071847 | Abbott Medical Devices | — |
| Completed | A Post-Market Study Evaluating the Safety of Infinity DBS System With MR Conditional Labeling NCT03884231 | Abbott Medical Devices | — |
| Recruiting | Deep Brain Stimulation (DBS) Retrospective Outcomes Study NCT03664609 | Boston Scientific Corporation | — |
| Unknown | Brain Network Activation in Patients With Movement Disorders NCT03269201 | Sheba Medical Center | — |
| Completed | Spine MRI in Patients With Deep Brain Stimulation (DBS) NCT03753945 | University Health Network, Toronto | N/A |
| Completed | Whole Body Vibration for Dystonia Cerebral Palsy NCT03779308 | The Hong Kong Polytechnic University | N/A |
| Completed | Database Of Clinical Data For Individuals With Variants In The IRF2BPL Gene NCT03892798 | Children's Hospital Medical Center, Cincinnati | — |
| Active Not Recruiting | The Motor Network in Parkinson's Disease and Dystonia: Mechanisms of Therapy NCT03582891 | University of California, San Francisco | N/A |
| Completed | Interactions Between Striatum and Cerebellum in ADCY5 and PRRT2 Dystonias NCT03481491 | Institut National de la Santé Et de la Recherche Médicale, France | N/A |
| Recruiting | Dystonia Genotype-Phenotype Correlation NCT03428009 | University of Texas Southwestern Medical Center | — |
| Active Not Recruiting | Deep Brain Stimulation Surgery for Focal Hand Dystonia NCT02911103 | National Institute of Neurological Disorders and Stroke (NINDS) | Phase 1 / Phase 2 |
| Completed | Efficacy and Safety of DBS in Patients With Primary Dystonia NCT03017586 | Beijing Pins Medical Co., Ltd | N/A |
| Completed | Pathophysiology of Focal Hand Dystonia NCT03223623 | National Institute of Neurological Disorders and Stroke (NINDS) | N/A |
| Completed | Exercise Training in Dystonia NCT03318120 | University of Florida | N/A |
| Terminated | Effect of the Visual Information Change in Functional Dystonia NCT03270189 | Fondation Ophtalmologique Adolphe de Rothschild | N/A |
| Completed | Efficacy of Botulinum Toxin for the Treatment of Dystonia Associated With Parkinson's Disease and Atypical Par NCT04948684 | Hospital Avicenne | — |
| Completed | Meditoxin® Treatment in Patients With Cervical Dystonia NCT03232320 | Medy-Tox | Phase 3 |
| Completed | Clinical and Physiological Studies of Tremor Syndromes NCT03027310 | National Institute of Neurological Disorders and Stroke (NINDS) | — |
| Completed | Assessing Cervical Dystonia NCT03587350 | The Leeds Teaching Hospitals NHS Trust | N/A |
| Completed | Thalamic Deep Brain Stimulation for Secondary Dystonia in Children and Young Adults NCT03078816 | University of California, San Francisco | N/A |
| Completed | Cholinergic Receptor Imaging in Dystonia NCT02689466 | National Institute of Neurological Disorders and Stroke (NINDS) | — |
| Completed | Osteopathic Manual Treatment Parkinson's Disease and Truncal Dystonia NCT03307161 | New York Institute of Technology | N/A |
| Completed | Blepharospasm Tools NCT02780336 | Emory University | — |
| Enrolling By Invitation | Effects of Stimulation Patterns of Deep Brain Stimulation NCT02553525 | Duke University | N/A |
| Recruiting | Vercise™ DBS Dystonia Prospective Study NCT02686125 | Boston Scientific Corporation | — |
| Completed | Role of the Striatal Cholinergic System in the Pathophysiology of Dystonia NCT02727361 | University Hospital, Bordeaux | N/A |
| Completed | rTMS and Botulinum Toxin in Primary Cervical Dystonia NCT02542839 | University of Florida | N/A |
| Unknown | Clinical Trial of STN-DBS for Primary Cranial-Cervical Dystonia NCT02583074 | Beijing Tiantan Hospital | N/A |
| Completed | Novel Stimulation Patterns for the Treatment of Dystonia NCT02468843 | University of Florida | — |
| Unknown | The Effects of Cannabis on Dystonia and Spasticity on Pediatric Patients NCT02470325 | Wolfson Medical Center | Phase 2 |
| Completed | A Randomized Controlled Trail Comparing Subthalamic and Pallidal Deep Brain Stimulation for Dystonia NCT02263417 | Beijing Pins Medical Co., Ltd | Phase 4 |
| Terminated | Dystonia Coalition Projects NCT04156022 | University of Texas Southwestern Medical Center | — |
| Active Not Recruiting | ExAblate Transcranial MRgFUS for the Management of Treatment-Refractory Movement Disorders NCT02252380 | InSightec | N/A |
| Unknown | Multi-Target Pallidal and Thalamic Deep Brain Stimulation for Hemi-Dystonia NCT02982304 | University of British Columbia | Phase 1 |
| Enrolling By Invitation | Sensory Gating Measured With Microelectrode Recording (MER) During Deep Brain Stimulation (DBS) Surgery NCT02320266 | University of Colorado, Denver | — |
| Completed | Incobotulinum Toxin A (Xeomin®) As A Treatment For Focal Task-Specific Dystonia Of The Musician's Hand NCT02107261 | Icahn School of Medicine at Mount Sinai | Phase 2 |
| Completed | Local Fields Potentials Recorded From Deep Brain Stimulating Electrodes NCT02071446 | University of Colorado, Denver | — |
| Completed | MyoSense- Automated Muscle Hypertonicity Classification System NCT02076581 | Great Lakes NeuroTechnologies Inc. | — |
| Completed | Pilot Trial of Botulinum Toxin and Occupational Therapy for Writer's Cramp NCT02015039 | National Institute of Neurological Disorders and Stroke (NINDS) | Phase 1 / Phase 2 |
| Completed | The Effects of Repetitive Paired Associative Stimulation in Dystonia NCT01888926 | National Institute of Neurological Disorders and Stroke (NINDS) | — |
| Unknown | Perceptual Decision Making Under Conditions of Visual Uncertainty NCT01845883 | University of California, Los Angeles | N/A |
| Completed | Functional Magnetic Resonance Imaging (fMRI) During Deep Brain Stimulation (DBS) to Treat Parkinson's Disease NCT01809613 | Mayo Clinic | — |
| Terminated | Transcranial Magnetic Stimulation for Focal Hand Dystonia NCT01792336 | National Institute of Neurological Disorders and Stroke (NINDS) | — |
| Suspended | Effect of Increasing Motor Cortex Inhibition on Task Specific Dystonia NCT01823237 | Emory University | N/A |
| Completed | Magnetic Resonance (MR) Guided Functional Ultrasound-Neurosurgery for Movement Disorders NCT01698450 | University Children's Hospital, Zurich | Phase 1 |
| Withdrawn | Surface EMG Biofeedback for Children With Cerebral Palsy NCT01681888 | University of Southern California | N/A |
| Completed | Can Short Latency Afferent Inhibition Give us Clues to Better DYT 1 Dystonia Treatments? NCT01435681 | University of Florida | — |
| Completed | Functional Connectivity in Primary Focal Dystonia NCT01761903 | University of Colorado, Denver | — |
| Completed | Validating a New Writer s Cramp Scale NCT01579266 | National Institute of Neurological Disorders and Stroke (NINDS) | — |
| Completed | Studying Childhood-Onset Hemidystonia NCT01432899 | National Institutes of Health Clinical Center (CC) | — |
| Completed | Ampicillin for DYT-1 Dystonia Motor Symptoms NCT01433757 | University of Florida | Phase 1 |
| Recruiting | Deep Brain Stimulation Surgery for Movement Disorders NCT01581580 | National Institute of Neurological Disorders and Stroke (NINDS) | N/A |
| Completed | Abnormal Movements, Cerebellum and Sensorimotor : Oculomotor Study NCT01495897 | Institut National de la Santé Et de la Recherche Médicale, France | N/A |
| Recruiting | Clinical Outcomes for Deep Brain Stimulation NCT03992625 | Washington University School of Medicine | — |
| Completed | The Dystonia Coalition Natural History and Biospecimen Repository for Isolated Dystonias NCT01373424 | Emory University | — |
| Completed | Cerebellum and Cortical Plasticity: the Case of Dystonia NCT01272154 | Institut National de la Santé Et de la Recherche Médicale, France | N/A |
| Completed | Physiological Brain Atlas Development NCT01210534 | Ohio State University | — |
| Completed | Effect of Deep Brain Stimulation (DBS) on Sleep Architecture in Patients With Movement Disorders NCT01169324 | University of Alabama at Birmingham | N/A |
| Completed | Neurotransmitter Measurements Using (WINCS) During Deep Brain Stimulation Neurosurgery NCT01705301 | Mayo Clinic | — |
| Completed | Physiological Investigations of Movement Disorders NCT01019343 | National Institute of Neurological Disorders and Stroke (NINDS) | N/A |
| Unknown | Alteration of Deep Brain Stimulation Parameters for Dystonia NCT00971854 | University of Oxford | N/A |
| Completed | RECHARGE Sub-Study to the Implantable Systems Performance Registry (ISPR) NCT00998660 | MedtronicNeuro | Phase 4 |
| Completed | Fatigue in Dystonia (a Single Session, Questionnaire-based Study of Fatigue in Dystonia) NCT00954408 | University of Florida | — |
| Completed | Amantadine for Improving Neurologic Symptoms in Ataxia-Telangiectasia NCT00950196 | Sheba Medical Center | Phase 4 |
| Completed | Deep Brain Stimulation in Patients With Dystonia NCT00773604 | University of California, San Francisco | N/A |
| Recruiting | Studies of the Variable Phenotypic Presentations of Rapid-Onset Dystonia Parkinsonism and Other Movement Disor NCT00682513 | State University of New York at Buffalo | — |
| Completed | Theta-burst Transcranial Magnetic Stimulation NCT00878787 | University of Southern California | N/A |
| Withdrawn | Dexmedetomidine Effects on Microelectrode Recording in Deep Brain Stimulation NCT00608231 | Vanderbilt University | Phase 2 / Phase 3 |
| Terminated | Effect of Vocal Exercise After Botulinum Toxin Injection for Spasmodic Dysphonia NCT00895063 | NYU Langone Health | N/A |
| Completed | Research of Biomarkers in Parkinson Disease NCT00465790 | Institut National de la Santé Et de la Recherche Médicale, France | — |
| Terminated | Brain Changes in Blepharospasm NCT00487383 | National Institute of Neurological Disorders and Stroke (NINDS) | — |
| Completed | Use of EMG to Assess Clinical Hypertonia NCT00472914 | University of Southern California | — |
| Unknown | Sedation During Microelectrode Recordings Before Deep Brain Stimulation for Movement Disorders. NCT00355927 | Hadassah Medical Organization | N/A |
| Completed | DYSCAR: Characterization of Dystonia NCT00361465 | University Hospital, Grenoble | — |
| Recruiting | Physiological Brain Atlas Development NCT00575081 | Vanderbilt University Medical Center | — |
| Unknown | Efficacy and Safety of Deep Brain Stimulation (DBS) of the Pallidal (GPi) in Patients With Tardive Dystonia NCT00331669 | Charite University, Berlin, Germany | Phase 2 |
| Completed | Quantification of Upper Extremity Hypertonia NCT00285870 | University of Southern California | — |
| Completed | Pallidal Stimulation in Patients With Post-anoxic and Idiopathic Dystonia NCT00169338 | Marie-laure Welter | Phase 2 |
| Completed | Transcranial Electrical Polarization to Treat Focal Hand Dystonia NCT00106782 | National Institute of Neurological Disorders and Stroke (NINDS) | Phase 2 |
| Completed | Deep Brain Stimulation for Cervical Dystonia NCT00105430 | National Institute of Neurological Disorders and Stroke (NINDS) | Phase 2 |
| Unknown | Bilateral Internal Pallidum Stimulation in Primary Generalized Dystonia NCT00272246 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | Phase 2 / Phase 3 |
| Completed | Brain Function in Focal Dystonia NCT00102999 | National Institute of Neurological Disorders and Stroke (NINDS) | — |
| Completed | Neurophysiological Markers in Patients With Craniofacial Dystonia and Their Relatives NCT00082615 | National Institute of Neurological Disorders and Stroke (NINDS) | — |
| Completed | The Physiology of Tricks NCT00072956 | National Institute of Neurological Disorders and Stroke (NINDS) | — |
| Completed | Use of Interventional MRI for Implantation of Deep Brain Stimulator Electrodes NCT00792532 | University of California, San Francisco | — |
| Completed | Childhood Hypertonia of Central Origin: A Trial of Anticholinergic Treatment Effects NCT00122044 | University of Southern California | Phase 2 |
| Unknown | Efficacy and Safety of DBS of the GPi in Patients With Primary Generalized and Segmental Dystonia NCT00142259 | German Parkinson Study Group (GPS) | Phase 4 |
| Terminated | Brain Anatomy in Dystonia NCT00031369 | National Institute of Neurological Disorders and Stroke (NINDS) | — |
| Completed | Mexiletine for the Treatment of Focal Dystonia NCT00001784 | National Institute of Neurological Disorders and Stroke (NINDS) | Phase 2 |
| Completed | Deep Brain Stimulation in Treating Patients With Dystonia NCT00004421 | Icahn School of Medicine at Mount Sinai | Phase 2 / Phase 3 |
| Approved For Marketing | Humanitarian Device Exemption NCT00580658 | Vanderbilt University Medical Center | — |
| Unknown | Pallidal Stimulation in Patients With Idiopathic Generalised Dystonia NCT00169403 | Groupe Hospitalier Pitie-Salpetriere | Phase 3 |