NCT01210534

Physiological Brain Atlas Development

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 456 (actual)
• Sponsor: Ohio State University · Academic / Other
• Sex: All
• Age: 7 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

Enrollment of candidates undergoing a deep brain stimulator (DBS) implant.

Detailed description

The study proposes the enrollment of candidates undergoing a deep brain stimulator (DBS) implant. Data will be collected before, during and after surgery and will be electronically entered into the Atlas database where it will be stored indefinitely. The purpose of the study is to create an Atlas to store physiological information utilizing non-rigid MRI normalization algorithms. In addition to collating and analyzing the physiological atlas in a statistical manner that allows the surgeon to predict optimal targeting locations for DBS implants based on multiple physiological variables, including pre-operative severity of disease, intraoperative neurophysiological observations, and post-operative response to DBS stimulation therapy.

Conditions

• Parkinson Disease
• Dystonia
• Tremors
• Obsessive Compulsive Disorder
• Depression

Interventions

Type	Name	Description
OTHER	No intervention	No intervention

Timeline

• Start date: 2010-08-01
• Primary completion: 2021-08-31
• Completion: 2021-10-18
• First posted: 2010-09-28
• Last updated: 2023-02-13

Locations

1 site across 1 country: United States