NCT02780336

Blepharospasm Tools

Diagnostic and Rating Tools for Blepharospasm

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 405 (actual)
• Sponsor: Emory University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to develop new rating scales to help diagnose and measure the severity of blepharospasm. This is a condition involving a lot of blinking and spasms of eye closure that people can't control. This study will also test some video software to see if it can help diagnose people or tell the severity of disease using only a video recording of an exam. There is an additional plan to create an educational video to teach others the proper use of the scale and video software.

Detailed description

Blepharospasm is a chronic disorder characterized by too many contractions in the muscles around the eye and nearby facial muscles, leading to involuntary eye closure. This study involves a comprehensive evaluation for patients with blepharospasm, other eye and face disorders, and people without any neurologic or eye or face disorders. It addresses abnormal movements of the muscles around the eye, pain in those muscles, psychological accompaniments, and impact on regular daily life. The evaluation for each participant will be done on a single visit, and it may take up to 1.5 hours to complete. Each participant in this study will be asked to do the following: * Provide a copy of medical records and provide a medical history relating to the diagnosis of blepharospasm. * Have an examination by a neurologist or ophthalmologist to reveal the features and extent of dystonia or other eye and face disorders. The examination will be video recorded so it can be reviewed later by different experts. * Complete some questionnaires about quality of life and psychiatric well being The doctors will also complete various scales and questionnaires based on the participant's study visit.

Conditions

• Blepharospasm
• Dystonia
• Other Eye and Face Disorders

Interventions

Type	Name	Description
OTHER	No intervention.	Participants will complete questionnaires and interviews as well as have a neurological exam that will be video recorded. For this exam they will do simple movements (like looking at the camera, squeezing your eyes closed, moving your head, and writing).

Timeline

• Start date: 2016-08-01
• Primary completion: 2019-03-20
• Completion: 2019-03-20
• First posted: 2016-05-23
• Last updated: 2019-05-31

Locations

11 sites across 4 countries: United States, Canada, Germany, Italy