| Recruiting | Remote Ischemic Conditioning Plus Stenting for Symptomatic Carotid Artery Stenosis NCT07412249 | General Hospital of Shenyang Military Region | N/A |
| Not Yet Recruiting | Research on Ultrasound Diagnostic Criteria for Intracranial and Extracranial Arterial Serial Stenosis NCT06947720 | Xuanwu Hospital, Beijing | — |
| Not Yet Recruiting | Monitoring of Brain Metabolites Using Proton and Deuterium MR Techniques NCT06705010 | Insel Gruppe AG, University Hospital Bern | N/A |
| Recruiting | Residual Stenosis and Restenosis Following Carotid Endarterectomy With Primary Closure, A Prospective Tracking NCT07057297 | Charles University, Czech Republic | — |
| Not Yet Recruiting | Efficacy and Outcome of Carotid Endarterectomy for Symptomatic Carotid Stenosis NCT06756360 | Assiut University | — |
| Not Yet Recruiting | Cognitive Improvement After Carotid Stenting in Hyperbaric Oxygen Therapy Trial NCT05980195 | Beijing Tiantan Hospital | N/A |
| Recruiting | Selective Coronary Revascularization in Carotid Artery Disease Patients After Carotid Revascularization (SCORE NCT06546761 | Pauls Stradins Clinical University Hospital | — |
| Enrolling By Invitation | Risk Prediction Model for Cerebrovascular Events in Carotid Artery Stenosis NCT06452173 | Beijing Tiantan Hospital | — |
| Recruiting | Plaque and Brain Inflammation in Symptomatic Carotid Stenosis: Role of the Ficolin-2 NCT05850247 | Hospices Civils de Lyon | Phase 2 |
| Unknown | Comparison Between Different Techniques for Carotid Artery Endarterectomy NCT06207643 | Sohag University | N/A |
| Active Not Recruiting | Endovascular Treatment of Cerebrovascular Diseases Guided by Optical Coherence Tomography (OCT) Technology（CVD NCT06986330 | First Affiliated Hospital of Wannan Medical College | — |
| Completed | Direct Access Carotid Artery Stenting Using the Neuroguard IEP System (PERFORMANCE III) NCT05845710 | Contego Medical, Inc. | N/A |
| Unknown | Pre-operative Antihypertension Strategies-Carotid Artery Stenting NCT05905848 | West China Hospital | Phase 3 |
| Unknown | Study of Carotid Artery Stenosis Through the Integration of Multimodal Imaging and Computational Fluid Dynamic NCT06294496 | Sichuan Provincial People's Hospital | — |
| Unknown | Chorioretinal Vascularization and Electrophysiological Changes After Carotid Revascularization NCT05835869 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | N/A |
| Active Not Recruiting | Differences of the Postoperative Outcome for Carotid Surgery Patients Treated by Either Male or Female Surgeon NCT06485102 | University Hospital Augsburg | — |
| Unknown | Remote Ischemic Conditioning and Dynamic Cerebral Autoregulation in Patients With Intracranial and Extracrania NCT05599009 | The First Hospital of Jilin University | N/A |
| Recruiting | Carotid Artery Stenting During Endovascular Treatment of Acute Stroke NCT06511089 | University Medical Center Groningen | Phase 3 |
| Completed | Ultrasonographic Morphology Assessment of Low-grade Carotid Stenosis NCT05437991 | Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer | N/A |
| Unknown | Spider Versus Emboshield Distal Protection on Cerebral Microembolization During Vulnerable Plaque in Carotid A NCT04904250 | Xuanwu Hospital, Beijing | N/A |
| Active Not Recruiting | Symptomatic Carotid Outcomes Registry NCT05300737 | University of Maryland, Baltimore | — |
| Active Not Recruiting | Radial Versus Femoral Access For Carotid Artery Stenting NCT05416853 | The First Affiliated Hospital of University of Science and Technology of China | N/A |
| Active Not Recruiting | Reconstruction of the Carotid Bifurcation in Patients With Arterial Hypertension of 2-3 Degrees NCT05931003 | Samara State Medical University | N/A |
| Completed | ACtive Catheterization for EndovaScular TreatmentS NCT05355259 | Basecamp Vascular | N/A |
| Unknown | SSPC Evaluation on Carotid Artery Stenosis After Endarterectomy NCT05296876 | Shanghai Pudong Hospital | — |
| Unknown | Comprehensive Assessment of Atherosclerotic Ischemic Stroke Risk and Development of a Prediction Model NCT06315153 | Xuanwu Hospital, Beijing | — |
| Unknown | Ophthalmologic Outcomes in Patients With Carotid Artery Stenosis NCT05623293 | Universidade do Porto | — |
| Unknown | Safety and Effectiveness of Ticagrelor in Patients Undergoing Carotid Stenting NCT04091074 | Assiut University | Phase 1 |
| Unknown | Carotid Artery Stent Implantation in the Treatment of Vulnerable Plaque NCT05524207 | Beijing Tsinghua Chang Gung Hospital | — |
| Recruiting | Multicentric Study on Clopidogrel Resistance in DAPT for CAS (MULTI-RESCLOSA) NCT05566301 | IRCCS Policlinico S. Donato | — |
| Recruiting | TRAnscranial Doppler CErebral Blood Flow and Cognitive IMPAIRment in Heart Failure NCT05250349 | John Paul II Hospital, Krakow | — |
| Completed | Effects of aSPIrin Versus Aspirin Plus Low-dose RIvaroxaban on Carotid aTherosclerotic Plaque Inflammation NCT05797376 | Asan Medical Center | Phase 4 |
| Completed | Prospective Evaluation for Hybrid Cardiac Procedures NCT05143671 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Recruiting | Simultaneous Cardiac Surgery and Micronet-covered Stent Carotid Revascularization in High Perioperative Stroke NCT04973579 | John Paul II Hospital, Krakow | — |
| Withdrawn | Distal Versus Proximal Protection on Cerebral Microembolization During High-risk Carotid Artery Stenting NCT04872127 | Xuanwu Hospital, Beijing | N/A |
| Completed | Ultrafast Ultrasound Imaging Assesment of Carotid Plaque Neovascularization NCT04470687 | Assistance Publique - Hôpitaux de Paris | N/A |
| Unknown | Study of 68GaNOTA-Anti-MMR-VHH2 in Oncological Lesions, Cardiovascular Atherosclerosis, Syndrome With Abnormal NCT04758650 | Universitair Ziekenhuis Brussel | Phase 2 |
| Completed | The Effect of Hypoxic and Normoxic Cerebral Oximetry Levels on Cognitive Functions After Carotid Endarterectom NCT05652426 | Duzce University | — |
| Completed | Safety and Feasibility of the Infinity Catheter for Radial Access NCT04553549 | Rutgers, The State University of New Jersey | — |
| Recruiting | Endovascular Acute Stroke Intervention - Tandem OCclusion Trial NCT04261478 | Centre hospitalier de l'Université de Montréal (CHUM) | N/A |
| Active Not Recruiting | Protection Against Emboli During Carotid Artery Stenting Using the Neuroguard IEP System NCT04201132 | Contego Medical, Inc. | N/A |
| Completed | Optical Coherence Tomography Angiography Evaluation of Ocular Changes in Patients With Carotid Artery Stenosis NCT04326842 | First Affiliated Hospital of Harbin Medical University | — |
| Unknown | Hemathologic and Imagiologic Predictors of Stroke During Carotid Endarterectomy With Regional Anesthesia NCT04327492 | Universidade do Porto | — |
| Unknown | Atrial Fibrillation and Carotid Atherosclerosis in Ischemic Stroke Patients-(AFCAS) NCT04821700 | University of Thessaly | — |
| Unknown | Carotid Stenosis Management During COVID-19 Era - Pilot Study NCT04947046 | Zealand University Hospital | — |
| Completed | Neurocognitive Function After Carotid Thrombendarterectomy NCT05739357 | Clinical Hospital Centre Zagreb | N/A |
| Active Not Recruiting | Transcutaneous ARFI Ultrasound for Differentiating Carotid Plaque With High Stroke Risk NCT04063709 | University of North Carolina, Chapel Hill | N/A |
| Unknown | Noninvasive Evaluation for Carotid Artery Stenosis: The Carotid Stenotic Scan NCT04057183 | Phillip J Bendick | — |
| Completed | The ENROUTE Transcarotid Neuroprotection System (ENROUTE Transcarotid NPS) DW-MRI Evaluation NCT03982420 | Silk Road Medical | — |
| Completed | Carotid Region Calcifications and Orthopantomogram NCT03936881 | Rennes University Hospital | — |
| Unknown | Extracranial Carotid & Intracranial Arterial Stenosis in Ischemic Stroke NCT04162587 | Mansoura University Hospital | — |
| Unknown | Investigation of Plaque Instability Using Bevacizumab-800CW and MSOT NCT03757507 | G.M. van Dam | N/A |
| Terminated | Dental Carotid Cognitive Study NCT03755362 | University of Maryland, Baltimore | N/A |
| Unknown | Evaluation of Cerebrovascular Events in Patients With Occlusive Carotid Artery Disorders NCT03840265 | Semmelweis University Heart and Vascular Center | N/A |
| Terminated | STAND: iSchemic sTroke evAluated at Bed Side With ultrasouND NCT04180826 | Fondation Ophtalmologique Adolphe de Rothschild | — |
| Recruiting | The Management of Asymptomatic Carotid Stenosis NCT06882954 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Completed | Co-administration of Dexmedetomidine in Carotid Endarterectomy (CEA) NCT04662177 | Insel Gruppe AG, University Hospital Bern | Phase 4 |
| Completed | Major Adverse Cardiac Events After Carotid Endarterectomy NCT03596229 | Mahidol University | — |
| Completed | Embolic Signals Detection Study (Esds) in Candidates for Surgical Carotid Revascularisation NCT05134493 | Azienda Ospedaliero-Universitaria di Modena | — |
| Unknown | Lifestyle Modification Programme for Patients With Asymptomatic Carotid Artery Stenosis NCT03929354 | Western Vascular Institute, Ireland | N/A |
| Unknown | Endarterectomy vs Stenting in Chinese Asymptomatic Carotid Stenosis Patients NCT03737175 | Xuanwu Hospital, Beijing | N/A |
| Completed | PET-MRI Imaging in Patients With Acute Neurovascular Syndrome NCT03215563 | University of Edinburgh | — |
| Completed | PET-MRI Imaging in Patients With Symptomatic Carotid Artery Stenosis NCT03215550 | University of Edinburgh | — |
| Completed | Modified Method of Eversion Carotid Endarterectomy in Patients With Extensive Atherosclerotic Disease of Carot NCT04255316 | Pirogov Russian National Research Medical University | N/A |
| Completed | Short-Term Endogenous Hydrogen Sulfide Upregulation NCT03303534 | Brigham and Women's Hospital | N/A |
| Unknown | Retrospective Study of Carotid Surgery in Dijon NCT03631381 | Centre Hospitalier Universitaire Dijon | — |
| Unknown | Prognostic Value of Carotid CEUS in Acute Ischemic Stroke Patients NCT03283306 | Seoul National University Hospital | — |
| Unknown | Insulin Resistance in Patients After Carotid Revascularization NCT03419767 | Peking Union Medical College Hospital | Phase 4 |
| Completed | Evaluation of the Carotid Plaque Stability by Ultrafast-ultrasound Imaging (UF) NCT03234257 | French Cardiology Society | N/A |
| Completed | Arachidonic Acid Metabolism in Carotid Stenosis Plaque in Diabetic Patients NCT03202823 | Centre Hospitalier Universitaire Dijon | — |
| Unknown | Microembolisation After Carotid Revascularisation NCT03303430 | University Hospital, Geneva | — |
| Recruiting | Carotid Atherosclerosis : Innovative Imaging Biomarkers. Study Case-control NCT02748941 | Hospices Civils de Lyon | N/A |
| Completed | CARotid Mri of Atherosclerosis NCT04835571 | Linkoeping University | N/A |
| Completed | Remote Ischemic Preconditioning for Carotid Endarterectomy NCT02808754 | University of Pittsburgh | N/A |
| Completed | Melatonin in Patients Under Carotid Endarterectomy NCT03115034 | Peking Union Medical College Hospital | Phase 4 |
| Unknown | Role of the Type of Carotid Stent and Cerebral Protection on Cerebral Microembolization During Carotid Artery NCT02915328 | Centro Cardiologico Monzino | N/A |
| Unknown | Ocular Effects of Carotid Endarterectomy NCT02448355 | Shaare Zedek Medical Center | N/A |
| Completed | Structural Stability of Carotid Plaque and Symptomatology NCT02476396 | University of Wisconsin, Madison | — |
| Completed | Carotid Arteries Stenting Complications: Transradial Approach Versus Transfemoral NCT02722720 | Meshalkin Research Institute of Pathology of Circulation | N/A |
| Completed | Effect on Cerebral Oxygenation by Sevoflurane or Propofol Using Near-infrared Spectroscopy in Carotid Endarter NCT02609087 | Chonnam National University Hospital | Phase 4 |
| Completed | Patient and Provider Assessment of Lipid Management Registry NCT02341664 | Duke University | — |
| Completed | The ENROUTE Transcarotid Neuroprotection System (ENROUTE Transcarotid NPS) DW-MRI Study NCT03985774 | Silk Road Medical | — |
| Unknown | The Use of Anti-CD4 mAb-Fragment for Imaging of Local Inflammation in Patients With Carotid Artery Stenosis NCT00904254 | Technische Universität Dresden | Phase 2 |
| Completed | Complementary and Alternative Medicine Interventions in Targeting Pain NCT04845334 | Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria | N/A |
| Completed | Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial NCT02089217 | Mayo Clinic | N/A |
| Completed | Classification of Carotid Plaque With Computed Tomography With Fast kVp (Kilovolt Peak)-Switching Technique NCT02436967 | Karolinska Institutet | — |
| Completed | Cardiac Output and Duplex Sonography in Carotid Endarterectomy NCT02230358 | Medical University Innsbruck | N/A |
| Completed | Screening and Access to Health Care for Vascular Disease NCT01889485 | Endeavor Health | — |
| Unknown | Clopidogrel Resistance and Embolism in Carotid Artery Stenting NCT02133989 | Samsung Medical Center | Phase 3 |
| Completed | Cognitive Outcome After Carotid Surgery NCT02118233 | Lahey Clinic | — |
| Terminated | TRACER RGD-K5 Carotid Plaque Imaging Study NCT01968226 | The Cleveland Clinic | Phase 2 |
| Completed | Perioperative Time Course of MMP-9 and Its Inhibitor During Carotid Artery Stenting and Carotid Endarterectomy NCT03410576 | University of Pecs | — |
| Completed | Ultrasound Guided Intermediate Cervical Plexus Block and Additional Perivascular Local Anesthetic Infiltration NCT02336958 | Helios Research Center | N/A |
| Unknown | Revascularization of Extracranial Carotid Artery Stenosis NCT01994187 | Xuanwu Hospital, Beijing | — |
| Completed | Platelet Activity in Vascular Surgery for Thrombosis and Bleeding NCT01897103 | NYU Langone Health | — |
| Completed | Indocyanine Green Fluorescence Uptake in Human Carotid Artery Plaque NCT01873716 | Massachusetts General Hospital | Phase 1 |
| Completed | Revacept in Symptomatic Carotid Stenosis NCT01645306 | AdvanceCor GmbH | Phase 2 |
| Unknown | Accuracy of TCD Monitoring in Predicting Cerebral Hyperperfusion Syndrome After Carotid Endarterectomy NCT01799070 | Peking Union Medical College Hospital | — |
| Recruiting | Predictive Value of Neovascularization Within Asymptomatic Carotis Stenosis on CEUS NCT01732523 | University Hospital, Basel, Switzerland | — |
| Completed | Correlation Between Laboratory Markers and Origin of New Brain Ischemic Lesions After Carotid Stenting NCT02310191 | University Hospital Ostrava | — |
| Terminated | [F-18] RGD-K5 Positron Emission Tomography (PET) in Participants With Carotid Artery Stenosis NCT01602471 | Siemens Molecular Imaging | Phase 2 |
| Completed | CorMatrix ECM for Carotid Repair Following Endarterectomy Registry NCT01569594 | Elutia Inc. | — |
| Withdrawn | Alternative Sensory Presentation Formats in Asymptomatic Carotid Stenosis NCT01531868 | Rhode Island Hospital | N/A |
| Withdrawn | Detection of Coronary Stenosis With Intravenous Microbubbles NCT00580580 | University of Nebraska | N/A |
| Unknown | Effect of Blood Pressure on rSO2 in Carotid Endarterectomy (CEA) NCT01451294 | G.J. de Borst | N/A |
| Completed | Overlay of 3D Scans on Live Fluoroscopy for Endovascular Procedures in the Hybrid OR NCT01480206 | Philips Clinical & Medical Affairs Global | — |
| Completed | The MICHI NEUROPROTECTION SYSTEM: Evaluation of Performance in Carotid Artery Stent Procedures (The LOTUS Stud NCT01958294 | Silk Road Medical | N/A |
| Unknown | Clopidogrel and Atorvastatin Treatment During Carotid Artery Stenting NCT01572623 | Campus Bio-Medico University | Phase 4 |
| Completed | Gadobutrol Enhanced MRA of the Supra-aortic Vessels NCT01344447 | Bayer | Phase 3 |
| Completed | Carotid Endarterectomy Versus Carotid Artery Stenting? A Prospective Comparison of Neuropsychological Outcome NCT01337128 | University Ghent | N/A |
| Completed | GORE Flow Reversal System and GORE Embolic Filter Extension Study NCT01343667 | W.L.Gore & Associates | N/A |
| Unknown | Physiological Magnetic Resonance Imaging (MRI) to Improve Carotid Endarterectomy Outcomes NCT01272843 | Sunnybrook Health Sciences Centre | — |
| Completed | Histological Validation Of Carotid Plaque Composition In Preoperative Imaging NCT01456403 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | — |
| Completed | Oxidative Stress and Oxysterols Profiling in Patients With Carotid Revascularization NCT02630862 | University of Roma La Sapienza | N/A |
| Completed | Adapt Monorail Carotid Stent System: A Postmarket Clinical Follow-up Study NCT01133327 | Boston Scientific Corporation | N/A |
| Unknown | Associations Between Diabetes, Arterial Stiffness and Fibulin-1 in Patients Undergoing Heart- and Vascular Sur NCT01106573 | Odense University Hospital | — |
| Terminated | Use of Amplified Sound Signal to Identify Presence of Carotid and Femoral Stenosis NCT01599195 | Albert Einstein Healthcare Network | — |
| Unknown | Early Warning and Optimization Strategy in Carotid Endarterectomy NCT01210937 | Peking Union Medical College Hospital | Phase 4 |
| Completed | A New Oxygen Mask for Carotid Endarterectomy Under Local Anaesthesia NCT01064908 | Brighton and Sussex University Hospitals NHS Trust | — |
| Completed | Carotid Stenting in Patients With High Risk Carotid Stenosis ("Soft Plaque") NCT01274676 | Centro Cardiologico Monzino | N/A |
| Terminated | Effect of ARC1779 on Cerebral Microembolism in Patients Undergoing Carotid Endarterectomy NCT00742612 | Archemix Corp. | Phase 2 |
| Completed | Comparing Carotid Stenting With Endarterectomy in Severe Asymptomatic Carotid Stenosis NCT00772278 | Carmel Medical Center | Phase 4 |
| Completed | Effects of Carotid Stent Design on Cerebral Embolization NCT00830232 | Dallas VA Medical Center | N/A |
| Completed | A Randomized Trial of Clinical Decision Making in Asymptomatic Carotid Stenosis NCT01315288 | Henry Ford Health System | N/A |
| Terminated | Rho Kinase (ROCK) Inhibition in Carotid Atherosclerosis NCT00670202 | Brigham and Women's Hospital | Phase 2 |
| Completed | Platelet Inhibition and Transcranial Doppler (TCD)-Detected Microemboli During and After Carotid Artery Stenti NCT01146301 | R&D Cardiologie | Phase 4 |
| Completed | EValuation of Systemic Atherothrombosis in Patients With ARTerial Disease of the Lower Limbs NCT01224600 | Institut de l'Atherothrombose | — |
| Active Not Recruiting | Carotid Endarterectomy Versus Carotid Artery Stenting in Asymptomatic Patients NCT00883402 | University of Oxford | N/A |
| Completed | Percentage of Secondary Prevention Patients Treated to Their LDL-C Targets NCT00536796 | AstraZeneca | — |
| Completed | Percentage of Secondary Prevention Patients Treated to Their LDL-C Targets NCT00536965 | AstraZeneca | — |
| Completed | Cost-Effectiveness of a Specialized Ultrasound Instrument to Diagnose Carotid Stenosis as a Way to Reduce the NCT00417586 | DVX, LLC | — |
| Terminated | Post-Approval Study of the NexStent Carotid Stent System and the FilterWire EZ Embolic Protection System: SONO NCT00478673 | Boston Scientific Corporation | Phase 4 |
| Completed | Carotid Ultrasound Sub-Study of the Familial Atherosclerosis Study-observational Study NCT00976014 | University of Washington | — |
| Terminated | Evaluation of the TriActiv ProGuard System During Carotid Artery Stenting NCT00395785 | Kensey Nash Corporation | Phase 2 / Phase 3 |
| Withdrawn | A Study of the Effects of Minocycline on Cognitive Function After Carotid Endarterectomy NCT00401921 | Brigham and Women's Hospital | Phase 2 |
| Withdrawn | Study of Early Versus Delayed Carotid Endarterectomy (CEA) for Small to Medium-sized Ischemic Stroke Caused by NCT00315562 | University of California, San Diego | Phase 1 |
| Completed | Emboshield® and Xact® Post Approval Carotid Stent Trial (The EXACT Study) NCT00287508 | Abbott Medical Devices | Phase 4 |
| Terminated | Carotid Angioplasty and Stenting Versus Endarterectomy in Asymptomatic Subjects Who Are at Standard Risk for C NCT00106938 | Abbott Medical Devices | N/A |
| Completed | Coronary Angiography Before Elective Carotid Endarterectomy in Patients With Asymptomatic Coronary Artery Dise NCT02260453 | University of Roma La Sapienza | Phase 3 |
| Unknown | A Prospective, Non-Randomized, Evaluation of Low-Risk Patients Undergoing Carotid Stenting With ANgiomax (Biva NCT01273350 | SPSI d.b.a Capital Cardiovascular Associates | N/A |
| Completed | A Single Center of Carotid Stenting With Distal Protection for the Treatment of Obstructive Carotid Artery Dis NCT00178672 | The University of Texas Health Science Center, Houston | Phase 4 |
| Unknown | CARMEDAS: Cost-Effectiveness Analysis of Imaging Strategies in Symptomatic Carotid Stenosis NCT00131001 | Hospices Civils de Lyon | N/A |
| Completed | Carotid Revascularization Endarterectomy Versus Stenting Trial NCT00004732 | Rutgers, The State University of New Jersey | N/A |
| Completed | EVA3S: Endarterectomy Versus Angioplasty in Patients With Severe Symptomatic Carotid Stenosis NCT00190398 | Assistance Publique - Hôpitaux de Paris | Phase 3 |
| Completed | Paraoxonase and LDL Oxidation in Carotid Artery Disease NCT00011258 | US Department of Veterans Affairs | — |
| Completed | Cohort Study of Heart Rate Variability NCT00005399 | University of North Carolina, Chapel Hill | — |
| Completed | Dietary Antioxidants and Atherosclerosis NCT00005412 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Adipose Distribution and Atherosclerosis NCT00005348 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Diabetes and Risk of Ischemic Stroke. NCT06401902 | Institut Mutualiste Montsouris | — |
| Completed | Asymptomatic Carotid Artery Plaque Study (ACAPS) NCT00000469 | National Heart, Lung, and Blood Institute (NHLBI) | Phase 2 |
| Completed | Recurrent Carotid Stenosis NCT00000527 | Emory University | Phase 2 |
| Withdrawn | Stroke Prevention With Abciximab in Carotid Endarterectomy NCT00178451 | University of Rochester | Phase 1 / Phase 2 |