NCT02260453

Coronary Angiography Before Elective Carotid Endarterectomy in Patients With Asymptomatic Coronary Artery Disease

Randomized Controlled Trial Analyzing the Role of Systematic Preoperative Coronary Angiography Before Elective Carotid Endarterectomy in Patients With Asymptomatic Coronary Artery Disease

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 426 (actual)
• Sponsor: University of Roma La Sapienza · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate the potential benefit of systematic preoperative coronary angiography followed by selective coronary artery revascularization on the incidence of myocardial infarction (MI) in patients without a history of coronary artery disease (CAD) and undergoing carotid endarterectomy (CEA).

Detailed description

Patients candidates for CEA, with no history of CAD, a normal electrocardiogram (ECG), and a normal cardiac ultrasound were randomized in two groups. In group A (n = 216) all patients underwent coronary angiography before CEA +- coronary artery revascularization. In group B (n = 210) CEA was performed without coronary angiography.

Conditions

• Carotid Stenosis
• Coronary Stenosis

Interventions

Type	Name	Description
OTHER	Preoperative coronary angiography	If coronary disease is detected percutaneous intervention (PCI) or coronary artery bypass grafting (CABG) is applied
OTHER	Standard cardiac workup	EKG, transthoracic cardiac echocardiogram

Timeline

• Start date: 2005-01-01
• Primary completion: 2009-07-01
• Completion: 2012-06-01
• First posted: 2014-10-09
• Last updated: 2014-10-09