| Withdrawn | Multimodality Optical and Ultrasound Intravascular Imaging for Stent Optimization and Atheroma Assessment NCT05753085 | Barts & The London NHS Trust | N/A |
| Not Yet Recruiting | Clinical Evaluation of Radiation Reduction for Optimized Safety NCT06348875 | Angiowave Imaging | — |
| Recruiting | Single vs. Dual Antiplatelet Therapy in Elderly or HBR Patients Undergoing Percutaneous Intervention With DCB NCT06535568 | Fondazione Ricerca e Innovazione Cardiovascolare ETS | N/A |
| Not Yet Recruiting | Disease Characteristics of R-CAD NCT07239921 | Peking Union Medical College Hospital | — |
| Suspended | IonMAN II Trial- Early Feasibility Study of the IoNIR Ridaforolimus-Eluting Coronary Stent System NCT06071702 | Medinol Ltd. | N/A |
| Not Yet Recruiting | Wearable Devices Assist in the Detection, Screening, and Management of Major Diseases in Middle-aged and Elder NCT06980064 | Tongji Hospital | N/A |
| Not Yet Recruiting | A MAajor RAdiation-based PCI Study in STEMI and NSTEMI NCT06565793 | Centre Cardiologique du Nord | — |
| Not Yet Recruiting | Transit Time Flow Measurement in Coronary Surgery NCT06471062 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Recruiting | PBM as Strategy to CABG Anemic Patients Bypass Graft (CABG) NCT06542393 | Federal University of São Paulo | Phase 2 |
| Recruiting | Impact of Fast-rotation Coronary CT in Patients Undergoing Aortic Stenosis Workup NCT05709652 | David C. Rotzinger | N/A |
| Completed | CERROS Pilot Study NCT06252350 | Angiowave Imaging | — |
| Unknown | Factors Related to the Progression of Non-target Coronary Lesions NCT06248138 | Mei Gao | — |
| Recruiting | Study of Microvascular Dysfunction, CFR and Cardioprotective Effect of Early Administration of Esmolol in MI NCT06376630 | National Medical Research Center for Cardiology, Ministry of Health of Russian Federation | N/A |
| Enrolling By Invitation | Whole Blood Transcriptomic Signal According to Coronary Atherosclerotic Plaque Burden Assessed by CT Angiograp NCT06194526 | MultiplAI Health Limited | — |
| Completed | Angiography-Derived Quantitative Functional Assessment Versus Pressure-Derived FFR and IMR: The FAIR Study NCT06039748 | Shenzhen Raysight Intelligent Medical Technology Co., Ltd. | — |
| Recruiting | Drug-Coated Balloon vs. Drug-Eluting Stent for Clinical Outcomes in Patients With Large Coronary Artery Diseas NCT05846893 | B. Braun Medical Industries Sdn. Bhd. | N/A |
| Not Yet Recruiting | Reverse T-stenting and Minimal Protrusion With External Minicrush for Treatment of Complex Coronary Bifurcatio NCT05782738 | San Luigi Gonzaga Hospital | N/A |
| Unknown | Automatic Anatomical and Functional Classification of Coronary Arteries With Artificial Intelligence. NCT05810610 | Institut Mutualiste Montsouris | — |
| Terminated | CT in Calcified Coronary Arteries With Photon Counting Detector NCT05551351 | Region Örebro County | — |
| Unknown | Long-term Follow-up of a Randomized Comparison of Percutaneous Coronary Intervention Versus Coronary Artery By NCT05963620 | Heart Center Leipzig - University Hospital | — |
| Completed | Measuring Blood Flow in Heart Vessels With a New Fibre Optic Sensor NCT05346458 | Queen Mary University of London | N/A |
| Completed | Compare the Effectiveness and Safety of Two Different Kinds of Cutting Balloon in Coronary Artery Disease NCT05509296 | Sino Medical Sciences Technology Inc. | N/A |
| Unknown | Evaluation of the Functional Impact of Coronary Stenoses in Diabetics by Spectral CT NCT05471687 | Hospices Civils de Lyon | N/A |
| Active Not Recruiting | IonMAN Trial- First in Human Study of the IoNIR Ridaforolimus-Eluting Coronary Stent System NCT05364697 | Medinol Ltd. | N/A |
| Completed | Diastolic Hyperemia-Free Ratio in Patients With CAD NCT05421169 | Yonsei University | — |
| Completed | Investigation of the Ringer Perfusion Balloon Catheter (Ringer PTCA) NCT04862689 | Vascular Solutions LLC | N/A |
| Recruiting | iFR Guided Coronary Artery Bypass Grafting Surgery NCT04014140 | Prakash Punjabi | — |
| Recruiting | Physio-Anatomy Clinical Data Collection Study NCT05312164 | Gentuity, LLC | — |
| Active Not Recruiting | TARGET-PREMIER Trail in Evaluating the Safety and Efficacy of the Rapamycin Target Eluting Stent in CAS Treatm NCT04951050 | Shanghai MicroPort Medical (Group) Co., Ltd. | N/A |
| Completed | A Study to EXhibit Percutaneous Coronary Artery Dilatation With Non-Slip Element Balloon NCT04985773 | Infraredx | N/A |
| Completed | STAR and Deferred Stenting Study NCT05089864 | Saint Luke's Health System | N/A |
| Active Not Recruiting | Comparison of the Diagnostic Performance and Costs of FFRB Vs. Standard Care in Suspected Coronary Artery Dise NCT06681584 | National Heart Centre Singapore | — |
| Recruiting | AI Driven National Platform for CT cOronary Angiography for clinicaL and industriaL applicatiOns Registry NCT05509010 | National Heart Centre Singapore | — |
| Completed | Assessment of Lesion-Associated Myocardial Ischemia Based on Fusion Coronary CT Imaging NCT04680689 | Cardio Med Medical Center | — |
| Completed | DK Score Coronary Scoring Balloon: a RCT Trial to Evaluate Acute Lumen Gain (SCORE CHINA) NCT05250193 | DK Medical Technology (Suzhou) Co., Ltd. | N/A |
| Unknown | The Flash FFR Ⅱ Study NCT04575207 | Peking University First Hospital | N/A |
| Completed | BIONICS Small Vessels Trial EluNIR Ridaforolimus Eluting Coronary Stent System (EluNIR) in Coronary Stenosis T NCT04761939 | Medinol Ltd. | — |
| Recruiting | Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS NCT04634240 | University of British Columbia | N/A |
| Active Not Recruiting | The Elixir Bioadaptor vs. The Onyx Stent in De Novo Native Coronary Arteries NCT04192747 | Elixir Medical Corporation | N/A |
| Completed | DCB Angioplasty for Coronary Lesions: an OCT Analysis NCT04984135 | The First Affiliated Hospital of Dalian Medical University | — |
| Unknown | The Sensitivity and Specificity of CardioSimFFRct Analysis Software on Coronary Artery Stenosis NCT04569669 | CCRF Inc., Beijing, China | N/A |
| Unknown | Diagnostic Accuracy of CCTA-derived Versus AngiogRaphy-dErived QuantitativE Flow Ratio (CAREER) Study NCT04665817 | Fudan University | — |
| Completed | The Assessment Of Myocardial Viability Based On CTA/MRI Hybrid Models NCT04397198 | Cardio Med Medical Center | — |
| Completed | FUnctional diagnoSIs of corONary Stenosis (FUSION) NCT04356027 | Abbott Medical Devices | — |
| Completed | Saline-induced Distal to Aortic Coronary Pressure Ratio vs. Resting and Hyperemic Indices of Coronary Artery S NCT04284345 | University Hospital, Geneva | N/A |
| Terminated | Impact of Mitral Regurgitation on Coronary Haemodynamics and Instantaneous Effect of Transcatheter Mitral Valv NCT04245956 | University Hospital, Geneva | N/A |
| Unknown | Culotte Versus DK-CRUSH Technique in Non-left Main Coronary Bifurcation Lesions NCT04192760 | University Heart Center Freiburg - Bad Krozingen | N/A |
| Completed | Radiographic Imaging Validation and EvALuation for Angio iFR (ReVEAL iFR) NCT03857503 | Volcano Corporation | — |
| Completed | Bingo Drug-Coated Balloon in Real World NCT04234893 | Yinyi(Liaoning) Biotech Co., Ltd. | — |
| Recruiting | Comparison of Optical Coherence Tomography-derived Minimal Lumen Area, Invasive Fractional Flow Reserve and FF NCT03820492 | Insel Gruppe AG, University Hospital Bern | N/A |
| Terminated | IRIS-BioFreedom Cohort in the IRIS-DES Registry NCT03190057 | Seung-Jung Park | — |
| Completed | EluNIR Ridaforolimus Eluting Coronary Stent System in Patients at High Bleeding Risk (HBR)- EluNIR HBR Study NCT03877848 | Medinol Ltd. | — |
| Unknown | Enhanced Recovery After Surgery (ERAS) in Coronary Artery Bypass Graft / Off Pump Coronary Artery Bypass (CABG NCT03956420 | Silesian University of Medicine | — |
| Terminated | Evaluation of Effectiveness and Safety of Hybrid Coronary Revascularization NCT03788369 | Seung-Jung Park | — |
| Completed | Coronary Plaque Geometry and Acute Coronary Syndromes NCT03702764 | Cardio Med Medical Center | — |
| Completed | Assessing the Accuracy of the OptoWire DeuxTM in a Wire to Wire Comparison NCT03815032 | Centre hospitalier de l'Université de Montréal (CHUM) | N/A |
| Unknown | Ultrathin DES in Complex PCI Scenarios: the ULTRA a Multicenter Study NCT05205148 | A.O.U. Città della Salute e della Scienza | — |
| Unknown | The FAVOR III China Study NCT03656848 | China National Center for Cardiovascular Diseases | N/A |
| Recruiting | IRIS- DESyne X2 in the IRIS-DES Registry NCT03588481 | Seung-Jung Park | — |
| Completed | BIONICS 38 mm Trial EluNIR Ridaforolimus Eluting Coronary Stent System (EluNIR) In Coronary Stenosis Trial NCT03702608 | Medinol Ltd. | N/A |
| Completed | Artimes Pro Low Profile Dilatation Catheters for Pre-Dilatation in Patients With Symptomatic Ischemic Heart Di NCT03301246 | Eminence Clinical Research, Inc. | N/A |
| Completed | Systemic, Pancoronary and Local Coronary Vulnerability NCT03606330 | Cardio Med Medical Center | — |
| Completed | Complex All-comers and Patients With Diabetes or Prediabetes, Treated With Xience Sierra Everolimus-eluting St NCT04475380 | Foundation of Cardiovascular Research and Education Enschede | — |
| Recruiting | Evaluation of Effectiveness and Safety of Rotational Atherectomy in Routine Clinical Practice NCT03427996 | Seung-Jung Park | — |
| Terminated | POLish Bifurcation Optimal Treatment Strategy Study for Left Main Bifurcation Percutaneous Coronary Interventi NCT03508219 | ECRI bv | N/A |
| Terminated | Percutaneous Treatment of LONG Native Coronary Lesions With Drug-Eluting Stent-VII: Sirolimus-eluting (Ultimas NCT03484234 | Seung-Jung Park | N/A |
| Completed | ILUMIEN IV: OPTIMAL Percutaneous Coronary Intervention (PCI) NCT03507777 | Abbott Medical Devices | N/A |
| Completed | Periodontal Disease, Inflammation and Acute Coronary Syndromes NCT03395041 | Cardio Med Medical Center | — |
| Recruiting | Asan Medical Center Myocardial Infarction Registry NCT03412435 | Seung-Jung Park | — |
| Completed | Multiomics and Imaging-based Assessment of Vulnerable Coronary Plaques in Acute Coronary Syndromes NCT03391908 | Cardio Med Medical Center | — |
| Completed | An Evaluation of a Physiology-guided PCI Optimisation Strategy NCT03259815 | NHS National Waiting Times Centre Board | N/A |
| Completed | 18F-fluorocholine PET-MR Imaging of Coronary Plaque Vulnerability NCT03252990 | Maastricht University Medical Center | — |
| Withdrawn | IRIS-Firehawk® Cohort in the IRIS-DES Registry NCT03380286 | Duk-Woo Park, MD | — |
| Completed | Pronostic Impact of Flow Fraction Reserve on Intermediate Stenoses NCT03588455 | Fondation Hôpital Saint-Joseph | — |
| Terminated | Contrast Volume Reduction During PCI With the Use of a New Assisting Software Package NCT02927990 | Philips Clinical & Medical Affairs Global | — |
| Terminated | HOW To Optimally Implant BioResorbable Scaffold - Intravascular Imaging Versus Quantitative Coronary Angiograp NCT03175523 | Seung-Jung Park | N/A |
| Completed | Physiologic Assessment of Coronary Stenosis Following PCI NCT03084367 | Volcano Corporation | — |
| Unknown | Application of speCtraL Computed tomogrAphy to impRove specIficity of Cardiac compuTed tomographY NCT03139006 | UMC Utrecht | — |
| Completed | Comparison of Devices Evaluating Fractional Flow Reserve in Coronary Arteries NCT03052803 | University Hospital, Caen | — |
| Unknown | Evaluation of the Correlation Between the Coronary Stenosis Degree With FFRCT and the Grade of Stable Angina P NCT02802046 | Guiyang No.4 People's Hospital | — |
| Unknown | FrActional Flow Reserve Guided Drug Coated Balloon Only Strategy in De Novo coronarY Lesions (FADDY) NCT03452904 | Second Affiliated Hospital, School of Medicine, Zhejiang University | Phase 3 |
| Completed | Thin Strut Sirolimus-eluting Stent in All Comers Population vs Everolimus-eluting Stent NCT02870140 | ECRI bv | N/A |
| Unknown | Bioresorbable Polymer ORSIRO Versus Durable Polymer RESOLUTE ONYX Stents NCT02508714 | Thorax Centrum Twente | N/A |
| Unknown | Validation of a Predictive Model of Coronary Fractional Flow Reserve in Patients With Intermediate Coronary St NCT03054324 | National Heart Centre Singapore | — |
| Completed | Assess the Efficacy and Safety of RESTORE Paclitaxel Eluting Balloon Versus RESOLUTE Zotarolimus Eluting Stent NCT02946307 | ZhuHai Cardionovum Medical Device Co., Ltd. | N/A |
| Completed | Human Vasodilatory Effect of GLP-1 NCT03502083 | Papworth Hospital NHS Foundation Trust | N/A |
| Completed | Computed Tomography (CT) Coronary Angiogram Evaluation in Cancer Patients Having CT Thorax, Abdomen and Pelvis NCT02275143 | University Hospital Plymouth NHS Trust | — |
| Unknown | Test Efficacy With Bioresorbable Polymer Coating Versus Bioresorbable Polymer Backbone (ISAR-RESORB) NCT02421016 | Deutsches Herzzentrum Muenchen | N/A |
| Completed | Study Comparing the MiStent SES Versus the XIENCE EES Stent NCT02385279 | ECRI bv | N/A |
| Completed | 3D-QFR in Non-selected Angiographic Stenosis. A Spanish Multicentre Study. NCT05251012 | Pablo Manuel Fernandez Corredoira | — |
| Withdrawn | Relationship Between Pressure and Flow Velocity on Coronary Physiology NCT02330861 | Hyogo Medical University | N/A |
| Completed | A Comparison of Fractional Flow Reserve-Guided Percutaneous Coronary Intervention and Coronary Artery Bypass G NCT02100722 | Stanford University | N/A |
| Completed | Contrast Enhancement on Coronary Computed Tomographic Angiography NCT02462044 | Maastricht University Medical Center | Phase 4 |
| Completed | Absorb IV Randomized Controlled Trial NCT02173379 | Abbott Medical Devices | N/A |
| Completed | Shockwave Coronary Lithoplasty Study NCT02758379 | Shockwave Medical, Inc. | N/A |
| Completed | Pharmacokinetics of Everolimus in Absorb BVS in Patients With Coronary Artery Lesions NCT02229864 | Abbott Medical Devices | N/A |
| Unknown | The ASSURE ROT Registry: Bioresorbable Vascular Scaffold Following Rotablation for Complex Coronary Lesions NCT01915420 | Medical Care Center Prof. Mathey, Prof. Schofer, Ltd. | — |
| Completed | A Clinical Evaluation of Absorb™ Bioresorbable Vascular Scaffold (Absorb™ BVS) System in Chinese Population ~ NCT01923740 | Abbott Medical Devices | N/A |
| Unknown | Combined Coronary and Cerebral Angiography and Intervention for Coronary and Cerebrovascular Atherosclerosis NCT02315924 | Capital Medical University | N/A |
| Completed | Comparison of BIOdegradable Polymer and DuRablE Polymer Drug-eluting Stents in an All COmeRs PopulaTion (BIO-R NCT01674803 | Foundation of Cardiovascular Research and Education Enschede | N/A |
| Completed | Teledi@Log - Tele-rehabilitation of Heart Patients NCT01752192 | Aalborg University | N/A |
| Completed | ABSORB III Randomized Controlled Trial (RCT) NCT01751906 | Abbott Medical Devices | N/A |
| Completed | Optical Coherence Tomography to Investigate FFR-Guided DEB-only Elective Coronary Angioplasty NCT02120859 | University of Jena | Phase 4 |
| Unknown | The Promus Element Rewards Study NCT01794065 | Medstar Health Research Institute | — |
| Completed | ABSORB: Postmarketing Surveillance Registry to Monitor the Everolimus-eluting Bioresorbable Vascular Scaffold NCT01583608 | Medical Care Center Prof. Mathey, Prof. Schofer, Ltd. | — |
| Unknown | Bifurcation Stenting Using 2 Link Stent Nobori Versus 3 Link Stent Xience NCT01574586 | Kurashiki Central Hospital | N/A |
| Withdrawn | Detection of Coronary Stenosis With Intravenous Microbubbles NCT00580580 | University of Nebraska | N/A |
| Unknown | Hybrid Sirolimus-eluting Versus Everolimus-eluting Stents for Total Coronary Occlusions NCT01516723 | R&D Cardiologie | Phase 3 |
| Terminated | The Treatment of Coronary De-novo Lesions With the Elutax Paclitaxel-eluting Balloon Alone, a Pilot Study NCT01899235 | Aalborg University Hospital | Phase 4 |
| Unknown | DUrable Polymer-based STent CHallenge of Promus ElemEnt Versus ReSolute Integrity NCT02175706 | Thorax Centrum Twente | N/A |
| Completed | DUrable Polymer-based STent CHallenge of Promus Element Versus ReSolute Integrity in an All Comers Population NCT01331707 | Foundation of Cardiovascular Research and Education Enschede | Phase 4 |
| Unknown | The Effect Of Remote Limb Ischemic Preconditioning For Carotid Artery Stenting NCT01175876 | Capital Medical University | Phase 1 |
| Completed | RESOLUTE Asia: Evaluation of the Endeavor Resolute Zotarolimus-Eluting Stent System in a Patient Population Wi NCT01132456 | Medtronic Vascular | N/A |
| Terminated | Chronic Total Occlusion Registry NCT04041921 | Seung-Jung Park | — |
| Completed | Vasodilator Free Measure of Fractional Flow Reserve NCT01118481 | Imperial College London | — |
| Completed | Trial Comparison of Accuseal and Bovine Pericardial Patch During Endarterectomy NCT01184183 | CAMC Health System | — |
| Completed | COMPETE: A Clinical Evaluation of Chrono Carbostent Carbofilm™ Coated Stent NCT00920283 | CID - Carbostent & Implantable Devices | N/A |
| Completed | Firefighter Aged Garlic Extract Investigation With CoQ10 as a Treatment for Heart Disease (FAITH) NCT00860847 | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | Phase 3 |
| Active Not Recruiting | Century Trial, a Randomized Lifestyle Modification Study for Management of Stable Coronary Artery Disease NCT00756379 | The University of Texas Health Science Center, Houston | N/A |
| Completed | Z-SEA-SIDE: Sirolimus Versus Everolimus Versus Zotarolimus-eluting Stent Assessment in Bifurcated Lesions and NCT01200693 | Catholic University of the Sacred Heart | Phase 4 |
| Completed | The Real-World Endeavor Resolute Versus XIENCE V Drug-Eluting Stent Study in Twente NCT01066650 | Foundation of Cardiovascular Research and Education Enschede | Phase 4 |
| Unknown | Coronary Computed Tomographic Angiography in Emergency Department Chest Pain Patients at Intermediate Risk of NCT00473863 | Vancouver General Hospital | Phase 3 |
| Completed | SEA-SIDE: Sirolimus Versus Everolimus-eluting Stent Randomized Assessment in Bifurcated Lesions and Clinical S NCT00697372 | Catholic University of the Sacred Heart | Phase 4 |
| Unknown | Diagnosis and Characterization of Coronary Artery Stenosis by Doppler Ultrasound NCT00521326 | Hillel Yaffe Medical Center | — |
| Completed | The Scanner in the Coronary Evaluation NCT00484380 | French Cardiology Society | N/A |
| Completed | Paclitaxel Eluting Balloon Versus Drug Eluting Stent in Native Coronary Artery Stenoses of Diabetic Patients NCT00462631 | Heart Centre Rotenburg | Phase 2 / Phase 3 |
| Completed | Maastricht Biomarker CT Study NCT01671930 | Maastricht University Medical Center | — |
| Unknown | Evaluation of a New Nanotechnology Based Drug-Eluting Stent for Opening of Narrowed Arteries of the Heart NCT00428662 | All India Institute of Medical Sciences | N/A |
| Completed | Sirolimus-eluting vs Zotarolimus-eluting Stents for Chronic Total Coronary Occlusions NCT00428454 | R&D Cardiologie | Phase 3 |
| Completed | Limus Eluted From A Durable Versus ERodable Stent Coating NCT00389220 | Biosensors Europe SA | N/A |
| Completed | Excel Drug-Eluting Stent Pilot Clinical Registry NCT00385905 | JW Medical Systems Ltd | Phase 4 |
| Unknown | Monitoring Response to Antiplatelet Therapy NCT00327041 | NHS Greater Glasgow and Clyde | — |
| Completed | PEPCAD I. The Paclitaxel-Eluting PTCA-Balloon Catheter to Treat Small Vessel NCT00404144 | Heart Centre Rotenburg | Phase 2 |
| Completed | Coronary Angiography Before Elective Carotid Endarterectomy in Patients With Asymptomatic Coronary Artery Dise NCT02260453 | University of Roma La Sapienza | Phase 3 |
| Completed | The Impact of Stent Deployment Techniques on Clinical Outcomes of Patient Treated With the CYPHER® Stent (S.T. NCT00403338 | Cordis US Corp. | — |
| Unknown | Long-term Outcome of Triple-vessel Coronary Artery Disease Underwent Three Different Strategies (LOTUS) NCT02634086 | Chinese Academy of Medical Sciences, Fuwai Hospital | — |
| Unknown | Percutaneous Coronary Intervention (PCI) With Drug-Eluting Stents (DES) Versus Coronary Artery Bypass Graft (C NCT00176397 | University of Leipzig | Phase 2 |
| Completed | Randomized Trial Evaluating Slow-Release Formulation TAXUS Paclitaxel-Eluting Coronary Stents to Treat De Novo NCT00301522 | Boston Scientific Corporation | Phase 2 / Phase 3 |
| Completed | Sirolimus-Eluting Stents for Chronic Total Coronary Occlusions NCT00258596 | R&D Cardiologie | Phase 3 |