NCT00580580

Detection of Coronary Stenosis With Intravenous Microbubbles

The Detection of Coronary Stenosis With Intravenous Mircrobubbles and Contrast Pulse Sequence Low Mechanical Index Imaging

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: University of Nebraska · Academic / Other
• Sex: All
• Age: 19 Years
• Healthy volunteers: Not accepted

Summary

To detect coronary artery disease by both coronary and carotid artery imaging and myocardial perfusion imaging using a new low mechanical index real time system.

Detailed description

The objective of this clinical study will be to visualize both coronary and carotid arteries as well as detect myocardial perfusion following a routine intravenous injection of Definity (0.05-0.20 millimeters), Optison (0.1-0.4 millimeters) or PESDA (0.05-0.2 mL). Following these injections , we will attempt to Contrast Pulse Sequencing on the Siemens Acuson Sequoia system to image both the coronary and carotid arteries, as well as the Myocardial perfusion.

Conditions

• Coronary Stenosis
• Carotid Stenosis
• Myocardial Reperfusion

Interventions

Type	Name	Description
DRUG	Optison	0.1-0.4 mL through intravenous injection at the beginning of the study.
DRUG	Definity	intravenous injection at 0.05-0.20 mL
DRUG	PESDA	intravenous injections dosage 0.05-0.20 mL

Timeline

• Start date: 2012-02-01
• Primary completion: 2013-03-01
• Completion: 2014-03-01
• First posted: 2007-12-24
• Last updated: 2024-09-23