NCT00976014

Carotid Ultrasound Sub-Study of the Familial Atherosclerosis Study-observational Study

Effects of Long-term Therapy With LDL-lowering Plus HDL Raising on Carotid Intima-media Thickness (CIMT) - Carotid Ultrasound Sub-Study of the Familial Atherosclerosis Study-observational Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 76 (actual)
• Sponsor: University of Washington · Academic / Other
• Sex: Male
• Age: —
• Healthy volunteers: Not accepted

Summary

This observational study looks at Carotid Stenosis in two groups of subjects using a non-invasive procedure, B-mode ultrasound. One group of subjects has had long-term intensive lipid altering therapy (lowering LDL-C plus raising HDL-C). The second group of patients has been on conventional "standard of care" treatment for carotid stenosis. The study will look at the Carotid Intima-media Thickness (CMIT) in both groups. Hypothesis: CIMT will differ between the two groups, such that the CIMT will be less in the subjects on intensive lipid altering therapy.

Conditions

• Carotid Stenosis

Timeline

• Start date: 2006-12-26
• Primary completion: 2012-05-09
• Completion: 2012-05-09
• First posted: 2009-09-14
• Last updated: 2021-12-16

Locations

1 site across 1 country: United States