| Not Yet Recruiting | A Study of Inhaled Cannabidiol in Healthy Occasional Cannabis Users NCT05320367 | Centre hospitalier de l'Université de Montréal (CHUM) | Phase 1 / Phase 2 |
| Suspended | Repeated Administration of Cannabis Varying in THC and CBD NCT05563948 | New York State Psychiatric Institute | Phase 2 |
| Not Yet Recruiting | Repeated CBD Administration and Cannabis Outcomes NCT07434895 | Hannah Harris | EARLY_Phase 1 |
| Completed | A Virtual Reality Game to Prevent E-cigarette and Cannabis Vaping NCT07413432 | Yale University | N/A |
| Recruiting | Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administration NCT05999383 | University of California, San Francisco | Phase 2 |
| Recruiting | Sex Hormones Impact on Cannabis Response NCT07417059 | Maastricht University | N/A |
| Enrolling By Invitation | Nicotine and Cannabis Vape Labeling Experiment - Spring 2025 NCT06919276 | University of Southern California | N/A |
| Recruiting | Reducing Breathlessness With Dronabinol in COPD Patients NCT06473701 | Vejle Hospital | Phase 3 |
| Withdrawn | Effect of Cannabis (Marijuana) on Stomach Emptying Before Surgery NCT05436236 | The Guthrie Clinic | — |
| Active Not Recruiting | Use of Cannabis Oil in Fibromyalgia NCT07194018 | Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria | — |
| Recruiting | Cannabis Observations on Brain Waves, Retrieval, and Attention: Experiment 3 NCT06669585 | L. Cinnamon Bidwell | — |
| Completed | Cannabis Edibles and Simulated Driving NCT06595576 | Centre for Addiction and Mental Health | N/A |
| Completed | Delta-8-THC vs. Delta-9-THC on Simulated Driving Performance NCT06218550 | Johns Hopkins University | Phase 1 |
| Recruiting | Modulation of THC Effects by CBD: a Dose-ranging Study NCT06099379 | Centre hospitalier de l'Université de Montréal (CHUM) | Phase 1 / Phase 2 |
| Recruiting | Evaluating Tetrahydrocannabinol as an Adjunct to Opioid Agonist Therapy NCT05985850 | BC Centre on Substance Use | Phase 2 |
| Recruiting | Age Differences in the Effects of Cannabis on Simulated Driving NCT04325958 | Centre for Addiction and Mental Health | N/A |
| Active Not Recruiting | Study on Regulated Cannabis Sales in Pharmacies NCT06120855 | University of Bern | N/A |
| Enrolling By Invitation | Responsible Marijuana Sales Practices to Reduce the Risk of Selling to Intoxicated Customers NCT06235632 | Klein Buendel, Inc. | N/A |
| Active Not Recruiting | The Pharmacokinetics of Single Dose Oral Tetrahydrocannabinol and Cannabidiol NCT05742724 | McMaster University | Phase 1 |
| Completed | Development and Evaluation of HighAlert NCT06098573 | Western University, Canada | N/A |
| Recruiting | Effects of Cannabidiol and Tetrahydrocannabinol on Microbiome and Neuroinflammation in HIV NCT05514899 | University of California, San Diego | Phase 2 |
| Unknown | An Integrated Program to Promote Anti-cannabis Messages NCT05899946 | The Hong Kong Polytechnic University | N/A |
| Unknown | Comparative PK Study Of THC/CBD Formulations NCT06149988 | CapSoil | Phase 1 |
| Completed | Investigating Real-world Stress-related Mechanisms in Heavy Cannabis Users NCT05833230 | Yale University | N/A |
| Enrolling By Invitation | Changes in Cognition and Psychiatric Disorder Symptoms During Cannabis Abstinence Using a Novel Discordant Twi NCT05160688 | University of Colorado, Denver | N/A |
| Recruiting | Cannabis' Impact on Alcohol Consumption NCT05389930 | Brown University | Phase 2 |
| Suspended | Dose-Ranging Trial of Inhaled Cannabis for Acute Migraine Treatment NCT05427630 | University of California, San Diego | Phase 2 |
| Completed | Joint Effort 2.0: a Mobile Application With University Students NCT05620433 | Centre hospitalier de l'Université de Montréal (CHUM) | N/A |
| Recruiting | ARISTOCRAT: Blinded Trial of Temozolomide +/- Cannabinoids NCT05629702 | University of Birmingham | Phase 2 |
| Unknown | Validation of the Cannabis Abuse Screening Test in General Practice(GP-CAST) NCT05633043 | University Hospital, Clermont-Ferrand | — |
| Completed | Improving Pain Disability With the Use of Oral Cannabinoids NCT05351905 | University Health Network, Toronto | N/A |
| Completed | Pain Inflammation and Cannabis in HIV NCT05554146 | Montefiore Medical Center | N/A |
| Completed | Cannabis Observations on Brain Waves, Retrieval, and Attention: Experiment 1 NCT05868213 | University of Colorado, Boulder | — |
| Withdrawn | Pain, Inflammation, and Cannabis in HIV NCT04860089 | Montefiore Medical Center | — |
| Completed | A Study of Ingested Cannabidiol in Healthy Occasional Cannabis Users NCT05407285 | Centre hospitalier de l'Université de Montréal (CHUM) | Phase 1 / Phase 2 |
| Active Not Recruiting | THC Memory & Reward Learning Pilot NCT05116527 | Hartford Hospital | Phase 1 / Phase 2 |
| Suspended | Transcranial Magnetic Brain Stimulation to Reduce Cannabis Use in Heavy Cannabis Users NCT05401929 | Duke University | N/A |
| Completed | Community Reinforcement and Family Training for Early Psychosis (CRAFT-EP) and Substance Use: A Pilot Study NCT05380583 | Mclean Hospital | N/A |
| Unknown | Sativex® and Gentamicin for Optimized Pharmagological Treatment in Older Patients (CanPan) NCT05503147 | Ove Andersen | Phase 1 |
| Completed | Cannabis, HIV and Mental Processing Systems NCT05430490 | Washington University School of Medicine | — |
| Completed | The Pharmacokinetics and Pharmacodynamics of a Single Acute Dose of a Hemp-derived Oral Product With a 1:1 Rat NCT05049733 | Johns Hopkins University | Phase 1 |
| Unknown | Detection of Cannabis Impairment With ISBRG's SpotLight-THC NCT05276232 | ISBRG Corp | Phase 1 |
| Completed | Development of a Lifestyle Physical Activity Intervention to Reduce Risk for Perinatal Cannabis Use NCT05528380 | Butler Hospital | N/A |
| Completed | Therapeutic Response of Cannabidiol in Rheumatoid Arthritis NCT04911127 | University of California, Los Angeles | Phase 1 |
| Completed | Cannabis Inhalation: Effects on Cardiovascular Function During Rest and Exercise NCT04693884 | Jamie Burr | EARLY_Phase 1 |
| Recruiting | Modeling the Effects of Chronic Marijuana Use on Neuroinflammation and HIV-related Neuronal Injury NCT04810858 | Wake Forest University Health Sciences | N/A |
| Suspended | Impact of Repeatedly-Administered THC-cannabis on Experimental Pain and Abuse Liability in Humans NCT04596644 | New York State Psychiatric Institute | Phase 2 |
| Completed | The Pharmacokinetics and Pharmacodynamics of Hemp-based Topical Cannabinoid Products NCT04741477 | Johns Hopkins University | Phase 1 |
| Withdrawn | Effects of THC and Alcohol on Driving Performance NCT03555968 | Lakehead University | Phase 4 |
| Completed | Repeated Cannabis Administration on Experimental Pain and Abuse Liability NCT04576507 | New York State Psychiatric Institute | Phase 2 |
| Unknown | EMERALD TRIAL Open Label Extension Study NCT04997954 | Gold Coast Hospital and Health Service | Phase 4 |
| Recruiting | A Pilot Study on the Effect of Cannabis Oil in Untreatable Liver Cancer Patients NCT06518434 | University Medical Center Groningen | Phase 2 |
| Completed | Impact of Reduced Cannabis Use on Functional Outcomes (R33 Phase) NCT04567238 | Duke University | N/A |
| Unknown | Methodology for Developing an Occlusal Appliance With CBD Active Carrier NCT04775030 | Medical University of Silesia | Phase 2 / Phase 3 |
| Completed | The Effect of Cannabidiol on Lean Body Mass in Patients Receiving Chemotherapy NCT04585841 | University of Copenhagen | Phase 1 |
| Completed | Efficacy of Inhaled Cannabis for Acute Migraine Treatment NCT04360044 | University of California, San Diego | Phase 2 |
| Completed | THC Crossover Study NCT04429568 | University of California, San Francisco | N/A |
| Completed | Full-spectrum Medical Cannabis for Treatment of Spasticity in Patients With Severe Forms of Cerebral Palsy NCT04634136 | University Medical Centre Ljubljana | N/A |
| Completed | Families With Substance Use and Psychosis: A Pilot Study NCT04284813 | Mclean Hospital | N/A |
| Completed | Analgesic Consumption in Chronic Marijuana Users Following Orthopedic Trauma Surgery NCT04587700 | University of Alberta | — |
| Completed | Behavioral Pharmacology of Cannabis and Nicotine NCT04124432 | Johns Hopkins University | Phase 1 |
| Completed | The Effect of Medical Cannabis on Tics, Premonitory Urge and Psychiatric Comorbidity in Adults With Tourette S NCT05115318 | Tel-Aviv Sourasky Medical Center | — |
| Completed | A Study Investigating the Bioavailability of CBD and THC in an Emulsion Product in a Healthy Population NCT04601207 | New Age Ventures LLC | Phase 1 |
| Completed | Enhancing Medication-based Analgesia in Humans- STUDY 2 NCT04036968 | Johns Hopkins University | Phase 2 |
| Unknown | Phase II Clinical Trial, Use of KL16-012 in Women With Fibromyalgia Refractary to Conventional Treatment. NCT04239469 | Knop Laboratorios | Phase 2 |
| Completed | The Study of Pharmacological Treatment Pattern for Cannabis-induced Psychosis NCT04945031 | Mahidol University | — |
| Recruiting | Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans: Sub-Study I NCT04704271 | Yale University | Phase 1 |
| Completed | THC and Ketamine Effects in Humans: Relation to Neural Oscillations and Psychosis NCT04199468 | Yale University | Phase 1 |
| Completed | Marijuana Effects on Simulated Driving Performance NCT03699540 | Shanna Babalonis, PhD | Phase 1 |
| Completed | Laboratory Smoking of Marijuana "Blunts" NCT03546790 | Battelle Memorial Institute | Phase 1 |
| Completed | Impact of Reduced Cannabis Use on Functional Outcomes NCT03681353 | Duke University | N/A |
| Completed | Do Adolescents and Adults Differ in Their Acute Response to Cannabis? NCT04851392 | University College, London | N/A |
| Unknown | The Effects of Cannabis on Visual Functions in Healthy and Retinitis Pigmentosa Patients NCT03078309 | Hadassah Medical Organization | EARLY_Phase 1 |
| Completed | Tetrahydrocannabinol (THC) and Sleep NCT03560934 | Oregon Health and Science University | EARLY_Phase 1 |
| Withdrawn | Cannabidiol Usage as an Adjunct Therapy for Crohn's Disease NCT03467620 | University of Illinois at Chicago | Phase 2 / Phase 3 |
| Completed | Effect of Cannabis and Endocannabinoids on HIV Neuropathic Pain NCT03099005 | University of California, San Diego | Phase 2 |
| Recruiting | Effect of Cannabis Extract on Acute Radicular Pain and on Analgesic Requirement NCT04816994 | Hadassah Medical Organization | Phase 3 |
| Completed | Myorelaxant Effect of Cannabis Cream Topical Skin Application in Patients With TMD NCT03994640 | Medical University of Silesia | Phase 2 / Phase 3 |
| Completed | Imaging the Neurochemistry of Drug Addiction With PET NCT02817698 | Yale University | EARLY_Phase 1 |
| Withdrawn | The Effect of Cannabis in Pancreatic Cancer NCT03245658 | Jens Rikardt Andersen | Phase 2 |
| Completed | Trial of Dronabinol and Vaporized Cannabis in Chronic Low Back Pain NCT02460692 | University of California, San Diego | Phase 2 |
| Completed | Enhancing Medication-based Analgesia in Humans NCT02901275 | Johns Hopkins University | Phase 2 |
| Completed | Duration of Marijuana Concentration in Breast Milk- A Pilot Study NCT02635568 | University of Colorado, Denver | — |
| Completed | Feasibility Trial of rTMS for Cannabis Use Disorder NCT03538288 | Medical University of South Carolina | N/A |
| Completed | Pharmacokinetic and Pharmacodynamic Effects of Smoked and Vaporized Cannabis NCT03676166 | Johns Hopkins University | Phase 1 |
| Completed | Cerebellar Alterations in Individuals With a Cannabis Use Disorder NCT02816034 | Universitat Pompeu Fabra | N/A |
| Completed | Intervening to Prevent Youth Access to Marijuana Phase II NCT03073291 | Klein Buendel, Inc. | N/A |
| Recruiting | Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans: Sub-Study I NCT02811510 | Yale University | Phase 1 |
| Active Not Recruiting | Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Sub-Study I NCT02709954 | Yale University | Phase 1 |
| Active Not Recruiting | Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Sub-Study II NCT02710097 | Yale University | Phase 1 |
| Active Not Recruiting | Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Substudy III NCT02710331 | Yale University | Phase 1 |
| Active Not Recruiting | Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition NCT02404688 | Yale University | Phase 1 |
| Terminated | Nabilone in Cannabis Users With PTSD NCT03251326 | New York State Psychiatric Institute | Phase 1 / Phase 2 |
| Completed | Excitatory rTMS to the Left Dorsolateral Pre-Frontal Cortex to Reduce Cannabis-Cue Induced Craving NCT02567344 | Medical University of South Carolina | N/A |
| Completed | Internet-Based Treatment for Individuals With Regular Cannabis Use: A Randomized Controlled Trial NCT02408640 | Karolinska Institutet | N/A |
| Recruiting | Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans NCT02781519 | Yale University | Phase 1 |
| Active Not Recruiting | Cannabinoids, Learning, and Memory NCT02407808 | Yale University | Phase 1 |
| Unknown | Colorado Marijuana Users Health Cohort NCT02735954 | National Jewish Health | — |
| Completed | Pharmacokinetic and Pharmacodynamic Effects of Oral Cannabis NCT02165176 | Johns Hopkins University | Phase 1 |
| Completed | Cannabinoids and Cerebellar-Motor Functioning NCT01853020 | Yale University | EARLY_Phase 1 |
| Completed | Effects of Inhaled Cannabis on Driving Performance NCT01620177 | Gary R Gaffney | N/A |
| Completed | Alcohol, Marijuana, and Risky Sex: Group Interventions With Detained Adolescents NCT01170260 | University of New Mexico | N/A |
| Completed | Web-based vs In-person Personalized Feedback Intervention for Comorbid Substance Use and Disordered Gambling NCT01529047 | University of Washington | N/A |
| Completed | Dronabinol Interactions With Cognitive Enhancing Drug in Humans NCT00842985 | Yale University | EARLY_Phase 1 |
| Completed | Cannabinoids, Neural Synchrony, and Information Processing NCT00708994 | Yale University | EARLY_Phase 1 |
| Completed | Effects of Sativex(Registered Trademark) and Oral THC on Attention, Affect, Working Memory, Reversal Learning, NCT01037608 | National Institute on Drug Abuse (NIDA) | Phase 1 |
| Completed | Antagonist-Elicited Cannabis Withdrawal NCT01041170 | National Institute on Drug Abuse (NIDA) | Phase 1 |
| Unknown | Family Motivational Intervention in Schizophrenia NCT01167556 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | N/A |
| Completed | Pharmacokinetics of THCCOOH and Its Acyl-glucuronide After Intravenous Administration of THCCOOH NCT00176085 | Heidelberg University | — |