NCT06919276

Nicotine and Cannabis Vape Labeling Experiment - Spring 2025

Longitudinal Patterns of Non-Combustible Tobacco Product Use in Adolescents (EPIC) / Assessing Development Patterns of Vaping, Alcohol, Nicotine, and Cannabis Use and Emotional Well-being (ADVANCE)

• Status: Enrolling By Invitation
• Phase: N/A
• Study type: Interventional
• Enrollment: 3,900 (estimated)
• Sponsor: University of Southern California · Academic / Other
• Sex: All
• Age: 11 Years – 19 Years
• Healthy volunteers: Accepted

Summary

This study assesses how the ways in which nicotine and cannabis vaping devices are labeled impact use susceptibility, anticipated effects, and health harm.

Detailed description

The primary objectives of the study: (1) Determine whether different device labels with the contained substance (nicotine or cannabis) affect adolescent use susceptibility, anticipated effects or impairment, and perceived health harms; (2) Determine whether device color/product flavor differentially impact the study outcomes.

Conditions

• Vaping
• Adolescent
• Electronic Cigarette Use
• Nicotine
• Cannabis

Interventions

Type	Name	Description
OTHER	Vaping Device Labeling	Participants will view one vape image (experimental stimulus) and are randomized to a label presented and the color/flavor of the vaping device presented. The label conditions are: 1. plain (i.e., no labeling on device) 2. "contains THC" 3. "contains 80% THC" 4. "contains 80% THC - HIGH POTENCY" 5. "contains nicotine" 6. "contains 5% nicotine" 7. "contains 5% nicotine - HIGH STRENGTH" The color/flavor conditions are: mint/mint, white/original, blue/blueberry.

Timeline

• Start date: 2025-03-03
• Primary completion: 2025-05-01
• Completion: 2025-06-01
• First posted: 2025-04-09
• Last updated: 2025-04-09

Locations

1 site across 1 country: United States