NCT03994640

Myorelaxant Effect of Cannabis Cream Topical Skin Application in Patients With TMD

Myorelaxant Effect of Cannabis Cream Topical Skin Application in Patients With Temporomandibular Disorders: a Randomized, Double-blind Study

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Medical University of Silesia · Academic / Other
• Sex: All
• Age: 22 Years – 27 Years
• Healthy volunteers: Accepted

Summary

Evaluation of myorelaxant effect of cannabis cream.compared to placebo cream in topical skin application in patients with TMD

Detailed description

Cannabis sativa has a very wide application in various fields of medicine. In patients with temporomandibular disorder, especially with myofascial pain of masticatory muscles there is a special need to seek an effective pain therapy and muscle relaxing methods. Patients with TMD suffer from chronic pain and depression, cannabis topical skin application therapy seems promising in that field. Patients attending The Department of TMD in Zabrze, Polska were randomly divided into two groups: experimental and placebo. sEMG activity values were compared during 14 days therapy with cream. Positive results were obtained confirming the efficacy of the cannabis cream used in the study, compared to placebo.

Conditions

• Temporomandibular Disorder
• Myofascial Pain
• Cannabis
• Electromyography

Interventions

Type	Name	Description
COMBINATION_PRODUCT	Cannabis Cream	Topical, bilateral skin application of cannabis cream with self-massage of masseter muscles
COMBINATION_PRODUCT	Placebo Cream	Topical, bilteral skin application of placebo cream with self-massage of masseter muscles

Timeline

• Start date: 2018-01-01
• Primary completion: 2018-10-01
• Completion: 2019-01-01
• First posted: 2019-06-21
• Last updated: 2019-06-21

Locations

1 site across 1 country: Poland