| Not Yet Recruiting | R01_Pilot Jaw Muscle Phenotypes NCT07153107 | University of Minnesota | N/A |
| Not Yet Recruiting | Evaluating Noninvasive Brain Stimulation for TMD Pain: A Feasibility Study NCT07517172 | University of Minnesota | N/A |
| Not Yet Recruiting | Forward Head Posture Correction Impact on Temporomandibular Dysfunction NCT06123351 | Shima Abdollah Mohammad Zadeh | N/A |
| Not Yet Recruiting | Low-Level Laser Auriculotherapy in the Treatment of Myogenic Temporomandibular Disorders and Anxiety NCT07125404 | Quiropraxia y Equilibrio | N/A |
| Not Yet Recruiting | Validation and Evaluation of the Mastication Function in Adults: The Functional Six-minute Mastication Test (F NCT06298786 | Fundació Universitària del Bages | — |
| Completed | Trauma Exposure and Childhood Trauma in Temporomandibular Joint Disorders NCT07292103 | Gulseren Demir Karakilic | — |
| Recruiting | Botulinumtoxin A as a Treatment for Myalgia and Myofacial Pain in Patient With Temporomandibulardisorders NCT06941636 | Region Stockholm | Phase 3 |
| Completed | Effect of Manual Therapy on Temporomandibular Joint Dysfunction NCT07210957 | Abant Izzet Baysal University | N/A |
| Not Yet Recruiting | Efficacy of Therapeutic Exercise and Pain Neurophysiology Education in Temporomandibular Disorders NCT06502769 | University of Alcala | N/A |
| Recruiting | Treatment of Temporomandibular Disorders in Children and Adolsecents NCT03849534 | Karolinska Institutet | N/A |
| Completed | TMJ Dysfunction: Effects on Proprioception, Pain, and Body Awareness NCT06558318 | Nagihan Acet | — |
| Completed | Temporomandibular Disorders Knowledge, Attitude, and Practice in Egypt NCT06977997 | Cairo University | — |
| Completed | Computer Guided Visco Supplementation in the Management of Internal Derangement of Temporomandibular Joint NCT06667791 | Hams Hamed Abdelrahman | N/A |
| Not Yet Recruiting | Effect of Chronic Low Back Pain Treatment on Temporomandibular Disorder" NCT06343155 | Medipol University | N/A |
| Recruiting | Neural Mechanisms of Immersive Virtual Reality in Chronic Pain (VR TMD EEG) NCT06214923 | University of Maryland, Baltimore | N/A |
| Recruiting | An Algorithm for Approaching Temporomandibular Disorders With Osteopathic Manual Therapy in Patients With Fibr NCT06365151 | Universitat de Lleida | N/A |
| Recruiting | K23- Physical Self Regulation vs Placebo NCT06357702 | Ian Boggero, PhD | N/A |
| Active Not Recruiting | Effect of Virtual Reality on TMD Following Maxillofacial Surgery NCT06537661 | Cairo University | N/A |
| Recruiting | Additional Effect of Forward Head Posture Correction on Temporomandibular Dysfunction NCT06156345 | Shima Abdollah Mohammad Zadeh | N/A |
| Recruiting | Electrical Stimulation of the Mandibular Nerve for Pain and Function Management in Temporomandibular Disorders NCT06265636 | OrigenKinesis fisioterapia | N/A |
| Recruiting | Temporomandibular Disorder in Use of Levonorgestrel Intrauterine System NCT06500390 | Marmara University | N/A |
| Completed | Effectiveness of the Fascial Distortion Model on the Cervical Spine in Individuals With Temporomandibular Diso NCT06186817 | Hacettepe University | N/A |
| Recruiting | Cognitive Exercise Therapy Approach Biopsychosocial Questionnaire (BETY-BQ) in Patient with Temporomandibular NCT06186830 | Hacettepe University | — |
| Unknown | Clinical and Radiographic Outcomes of CAD/CAM vs Conventionally Constructed Occlusal Splints in Patients With NCT04591899 | Cairo University | N/A |
| Completed | Efficacy of Manual Therapy Based on the Fascial Distortion Model in Individuals With Temporomandibular Disorde NCT06134310 | Hacettepe University | N/A |
| Completed | Forward Head Posture and Myogenic TMD Association in Smartphone Overuse NCT06065826 | Doha Hany Mohamed Labib | — |
| Unknown | The Relationship of Premenstrual Syndrome and Primary Dysmenorrhea With Severity of Temporomandibular Disorder NCT06052722 | Tokat Gaziosmanpasa University | N/A |
| Unknown | The Association Between Temporomandibular Disorders and Sacroiliac Joint Dysfunction NCT06035341 | Marmara University | N/A |
| Unknown | Muscle Energy Technique on Hamstring Muscle for Trigger Points of Muscle of Mastication NCT05971953 | Riphah International University | N/A |
| Completed | The Relationship Between Pain Perception, Severity of Temporomandibular Joint Dysfunction, and Spinal Health i NCT06053008 | Tokat Gaziosmanpasa University | N/A |
| Unknown | Association Among Pain Perception, Severity of Temporomandibular Joint Dysfunction, and Spinal Health in Careg NCT06052735 | Tokat Gaziosmanpasa University | N/A |
| Unknown | CBD (Cannabidiol) Intraoral Application and TMD (Temporomandibular Disorders) NCT05562635 | Medical University of Silesia | Phase 2 / Phase 3 |
| Unknown | Effect of Forward Head Correction on EMG of Masticatory Muscles in Patients With TMD NCT05756010 | Beirut Arab University | N/A |
| Unknown | Manual Therapy and Movement Control Exercises for Chronic Neck Pain. A Pilot Randomized Controlled Trial NCT06189612 | Hochschule Osnabruck | N/A |
| Completed | Management of Temporomandibular Disorders (TMD) NCT06759584 | Minia University | N/A |
| Unknown | Turkish Validity and Reliability of The Helkimo Index for Diagnosis of Temporomandibular Disorders NCT05749224 | Yeditepe University | N/A |
| Unknown | Correlation Between Occlussion Types , in Patients With Temporomandibular Disorders. NCT05680103 | Cairo University | — |
| Unknown | Effect of Exercises on Convergence Insufficiency in Individuals With Temporomandibular Disorders NCT05761106 | University of Nove de Julho | N/A |
| Completed | Temporomandibular Dysfunction in Patients With Diabetic Foot Ulcers NCT06067022 | Harran University | — |
| Unknown | Effects of Aerobic Exercise on Pain in Patients With Myogenous Temporomandibular Disorders and Suspicion of Ce NCT05540366 | Universitat Internacional de Catalunya | N/A |
| Completed | Non-Invasive Intravascular Laser Irradiation Of Blood In The Treatment Of Children With Temporomandibular Diso NCT05297604 | University of Nove de Julho | N/A |
| Withdrawn | Comorbid Painful TMD Among Trigeminal Neuralgia NCT05914558 | University of Minnesota | — |
| Completed | Telerehabilitation for TMD NCT05318313 | University of Minnesota | — |
| Completed | Effects of a Self-management Program for Temporomandibular Myalgia in Subjects With Fibromyalgia: a Single Arm NCT05426655 | Jose Edgar Ferrandez Gomez | N/A |
| Completed | INVESTIGATION AND COMPARISON OF THE EFFECTS OF POSTURE EXERCISES ON DYSFUNCTION, POSTURE AND BALANCE IN INDIVI NCT05704998 | Dokuz Eylul University | N/A |
| Unknown | Botulinum Toxin Administration on Masticatory Performance NCT05562531 | Marmara University | — |
| Recruiting | Intraoral Versus Extraoral Manual Therapy in Subjects With Temporomandibular Disorders NCT05167656 | University of Alcala | N/A |
| Completed | Temporamandibular Joint Functions and Parafunctional Habits NCT05580276 | Karadeniz Technical University | — |
| Completed | Myoelectric Activity and Mandibular Movement for the Diagnosis of Temporomandibular Disorder NCT06372769 | Stomatological Hospital Affiliated with Fujian Medical University | — |
| Enrolling By Invitation | Effectiveness of iPRF Injections in Temporomandibular Joints Degeneration Management NCT05214924 | Wroclaw Medical University | Phase 2 / Phase 3 |
| Unknown | Evaluation of Biofeedback Therapy Efficiency in Masticatory Muscles Pain Management NCT03421028 | Wroclaw Medical University | N/A |
| Completed | Evaluation of the Effect of Muscle Activity on Subjective Tinnitus in Temporomandibular Disorders NCT05830604 | Kutahya Health Sciences University | N/A |
| Completed | Safety and Efficacy of Erenumab-aooe in Patients With Temporomandibular Disorder NCT04884763 | Indiana University | Phase 2 |
| Completed | Pterygomaxillary Disjunction With Interpositional Y-shape Plate in Patients With Temporomandibular Joint Deran NCT05561465 | Hams Hamed Abdelrahman | N/A |
| Active Not Recruiting | Neural Mechanisms of Immersive Virtual Reality in Chronic Pain NCT04851301 | University of Maryland, Baltimore | Phase 1 / Phase 2 |
| Recruiting | How is Aerobic Exercise Compared to Localized Pain Relief Exercises in Patients With Jaw Pain and Neck Pain? NCT05232604 | Hochschule Osnabruck | N/A |
| Unknown | Stem Cells and Stromal Vascular Fraction for Temporomandibular Joint Disease NCT05305833 | TC Erciyes University | Phase 1 / Phase 2 |
| Recruiting | Tele-Rehabilitation in Patients With Temporomandibular Dysfunction NCT05006963 | University of Nove de Julho | N/A |
| Unknown | The Effect of Different Physiotherapeutic Stimuli on Stomatognathic System Structures. NCT05021874 | Pomeranian Medical University Szczecin | N/A |
| Completed | The Effect of Bruxism on Temporomandibular Disorders NCT04866849 | Yerkoy State Hospital | — |
| Unknown | Urdu Version of Fonseca Anamnestic Index: Reliability and Validity Study NCT05431829 | Riphah International University | — |
| Completed | Evaluation of the Relationship Between Neck Pain and Temporomandibular Disorders in Office Workers NCT04900870 | Tugba Sahbaz | — |
| Completed | Physical Exercises for Temporomandibular Disorders NCT04819763 | University Medicine Greifswald | N/A |
| Completed | Telerehabilitation in Individuals Temporomandibular Dysfunction With Bruxism NCT04884152 | Hasan Kalyoncu University | N/A |
| Completed | Prevalence of Temporomandibular Disorders in Patients With Fibromyalgia Syndrome NCT04867044 | Yerkoy State Hospital | — |
| Completed | the Relationship Between Parafunctional Habits, Pain and Functional Limitation of the Jaw NCT05029908 | Istanbul Physical Medicine Rehabilitation Training and Research Hospital | — |
| Completed | Effect Of Sleep Apnea Treatment On Temporo-Mandibular Disorders NCT04948541 | Anna Alessandri Bonetti | N/A |
| Completed | Standard Care With LLLT & Myofascial Release Versus Standard Care Alone in Pregnant Women With Temporomandibul NCT05138354 | October 6 University | N/A |
| Completed | Effectiveness of Different Physiotherapy Practices in Temporomandibular Disorders NCT04708938 | Gazi University | N/A |
| Completed | Assessment of Nociceptive Processing Among Patients With Temporo-mandibular Disorders NCT04086732 | Université Catholique de Louvain | N/A |
| Unknown | Methodology for Developing an Occlusal Appliance With CBD Active Carrier NCT04775030 | Medical University of Silesia | Phase 2 / Phase 3 |
| Completed | Temporomandibular Joint and COVID-19 NCT05077189 | Recep Tayyip Erdogan University Training and Research Hospital | — |
| Completed | Relationship Between Cervical Pain and Temporomandibular Dysfunction Craniovertebral Angle, Jaw Functional Lim NCT06623552 | Yeditepe University | — |
| Completed | Role of Liquid Phase Concentrated Growth Factors vs. Hypertonic Dextrose Prolotherapy for Management of Patien NCT04557878 | Nourhan M.Aly | Phase 2 |
| Completed | Efficacy of a Standardized Centella Asiatica Extract in Patients With Temporomandibular Disorder NCT06231212 | Chulalongkorn University | Phase 2 / Phase 3 |
| Unknown | A Comparative Study Using Two 3D Printed Occlusal Splints for Patients With Tempromandibular Disorder NCT04455672 | Cairo University | N/A |
| Unknown | Temporomandibular Disorders Among Patients With Tinnitus NCT04434859 | Tel-Aviv Sourasky Medical Center | — |
| Completed | Evaluation of Oxidative Stress and Inflammation Markers in Temporomandibular Disorders NCT05985733 | Bahçeşehir University | — |
| Completed | Effectiveness of a Home Based Exercise Program on Temporomandibular Dysfunction Syndrome NCT04374682 | Assiut University | — |
| Completed | Effects on Pain and Function of Orthopedic Manual Therapy in Patients With Painful Disc Displacement With Redu NCT05728905 | Fisioterapia Manual Ortopedica | N/A |
| Completed | Proprioceptive Neuromuscular Facilitation Exercises in Temporomandibular Dysfunction NCT04967131 | Istanbul Medipol University Hospital | — |
| Enrolling By Invitation | Relationship Between Selected Parameters and Bruxism NCT04214561 | Wroclaw Medical University | — |
| Completed | Validation of the TMD Pain Screener in a Specialized Headache Center NCT04193111 | Danish Headache Center | — |
| Completed | Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments NCT03844412 | Duke University | Phase 2 |
| Completed | Prevalence of Temporomandibular Disorders and Its Association With Oral Parafunctions, Neck Pain and Function NCT04495777 | Aydin Adnan Menderes University | — |
| Withdrawn | Platelet-rich Plasma Injection for Temporomandibular Disorders NCT04127942 | Tri-Service General Hospital | N/A |
| Completed | Efficacy and Safety of JHG002 for Chronic Temporomandibular Joint Dysfunction: A Multicenter Randomized Contro NCT04087005 | Jaseng Medical Foundation | N/A |
| Completed | Jaw Kinematics and Muscle Activation in Patients With Non-specific Chronic Neck Pain NCT04041271 | National Yang Ming Chiao Tung University | — |
| Completed | Evaluation of the Efficacy of Different Drugs in the Treatment of the Pain in Patients With Temporomandibular NCT05529290 | Yuzuncu Yil University | Phase 4 |
| Completed | Assessing a New Jaw Support Device During Third Molar Extractions NCT03975920 | University of Minnesota | N/A |
| Completed | The Effect Of Core Stability Training In Temporomandibular Disorders NCT04755621 | Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey | N/A |
| Completed | Manual Therapy and Splint Therapy in Patients With Temporomandibular Dysfunction NCT05352438 | Turkoglu Dr. Kemal Beyazit State Hospital | N/A |
| Unknown | Computer Guided Arthrocentesis of Temporomandibular NCT03844971 | Cairo University | N/A |
| Completed | Condylar Inclination Recorded With Modjaw® Device. NCT04694040 | Centre Hospitalier Universitaire de Nice | — |
| Terminated | Investigation and Modulation of the Mu-opioid Mechanisms in TMD (in Vivo) NCT03724032 | University of Michigan | N/A |
| Completed | Evaluation of Styloid Chain Calcification to the Patient With the Temporomandibular Joint Disorder NCT04280107 | Nuh Naci Yazgan University | — |
| Completed | Evaluation of an Intra Auricular Device as a Treatment for Painful Temporo-Mandibular Disorders NCT05365932 | Federico II University | N/A |
| Enrolling By Invitation | Determination of Chronic Pain, Anxiety, Depression and Perceived Stress in Adults With Temporomandibular Disor NCT05183503 | Wroclaw Medical University | — |
| Completed | Effectiveness of Physical Teraphy in the Treatment of Myogenic Temporomandibular Disorders NCT03726060 | Paolo Pillastrini | N/A |
| Unknown | Photobiomodulation With Red and Infrared LED Device for Temporomandibular Dysfunction NCT03696706 | University of Nove de Julho | Phase 2 |
| Completed | Assessing Motor Imagery Ability of Tongue and Mouth in Subjects With and With no Temporomandibular Disorders NCT04102306 | Cabinet de Kinesitherapie SCM Saint-Alexandre | — |
| Completed | Botulinum Toxin Versus Placebo Injections to Temporalis and Masseter Muscles NCT03223298 | Weill Medical College of Cornell University | Phase 3 |
| Completed | Effectiveness of a Manual Therapy Protocol in Patients With Masticatory Muscle Disorders NCT03556150 | University of Alcala | N/A |
| Completed | An Investigation Of The Relationship Between Temporomandibular Disorder With Posture And Pedobarographic Analy NCT03490643 | Istanbul Medipol University Hospital | N/A |
| Completed | Effect of Massage Treatment in Temporomandibular Joint NCT04132726 | Istanbul University | N/A |
| Completed | Occlusal Splints or Botulinum Toxin? NCT03891121 | Ankara University | N/A |
| Completed | Efficacy of Naproxen-codeine, Naproxen+Dexamethasone, and Naproxen on Myofascial Pain NCT04066426 | Yuzuncu Yil University | Phase 4 |
| Completed | Myorelaxant Effect of Cannabis Cream Topical Skin Application in Patients With TMD NCT03994640 | Medical University of Silesia | Phase 2 / Phase 3 |
| Completed | The Platelet-Rich Plasma in the Therapy of Temporomandibular Disorders NCT03371888 | Medical University of Silesia | Phase 2 / Phase 3 |
| Completed | Cervical Spine Thrust Joint Manipulation for Temporomandibular Disorder NCT03300297 | Bradley University | N/A |
| Unknown | Photobiomodulation in Temporomandibular Disorder NCT03096301 | University of Nove de Julho | N/A |
| Completed | Home Exercises Program Compared With Physiotherapy Program in TMD NCT05778890 | Nigde Omer Halisdemir University | N/A |
| Unknown | Consequences of Temporomandibular Disorder on Balance Control NCT03283839 | Central Hospital, Nancy, France | N/A |
| Completed | Efficacy Of Different Types Of Physiotherapy Approaches In Temporomandibular Disorders NCT04294602 | Bitlis Eren University | N/A |
| Enrolling By Invitation | Selected Disorders and Sleep Bruxism NCT03083405 | Wroclaw Medical University | — |
| Completed | Effects of Temporomandibular Disorder on Masticatory Efficiency NCT04379609 | Bahçeşehir University | — |
| Completed | Photobiomodulation In the Masseter and Temporal In Patients With Temporomandibular Joint Dysfunction NCT03005730 | University of Nove de Julho | N/A |
| Completed | Osteopathic Manipulative Treatment in Individuals With Temporomandibular Disorder Who Make Use of Occlusal Spl NCT02991326 | Universidade Federal Fluminense | N/A |
| Completed | Comparison of the Effectiveness of Three Different Treatment Methods in Myofascial Pain Patients NCT03400462 | Pomeranian Medical University Szczecin | N/A |
| Completed | The Use of Manual Muscle Relaxation Techniques in the Treatment of Temporomandibular Joint Disorders NCT05091996 | Jagiellonian University | N/A |
| Completed | Effectiveness of Photobiomodulation and Manual Therapy Alone or Combined in TMD Patients NCT03454581 | Federal University of Rio Grande do Sul | Phase 2 |
| Completed | An Internet-based Multimodal Pain Program for Chronic Temporomandibular Disorder Pain NCT04363762 | Malmö University | N/A |
| Completed | A Comparison of Collagen, Lidocaine and Saline, in Trigger Points in Masseter Muscle. NCT03323567 | Medical University of Silesia | EARLY_Phase 1 |
| Unknown | Assessment of the Efficacy of a Sensorimotor Approach After Maximum Three Sessions in Subjects With TMD With H NCT02632643 | Osteovox | N/A |
| Completed | The Effectiveness of a Physiotherapy Technique in Patients With Chronic Myofascial Temporomandibular Disorder NCT03619889 | Universidad Complutense de Madrid | N/A |
| Completed | DC/TMD Axis I for Children NCT04256811 | CES University | — |
| Completed | Electromyographic Analysis of the Masticatory Muscles in Cleft Lip and Palate Children With Temporomandibular NCT03308266 | Pomeranian Medical University Szczecin | — |
| Unknown | Effect of Phototherapy in Individuals With Temporomandibular Disorder. NCT02018770 | University of Nove de Julho | Phase 1 / Phase 2 |
| Completed | Influence of Stabilization Splint Thickness on The Temporomandibular Disorders NCT04524806 | Istanbul Medipol University Hospital | N/A |
| Unknown | Low-level Laser Therapy on Temporomandibular Disorder NCT01846000 | University of Nove de Julho | N/A |
| Completed | Analysis of the Effects of the Osteopathic Manipulative Treatment in Carriers of Temporomandibular Disorders NCT02974166 | Instituto Brasileiro de Osteopatia | N/A |
| Withdrawn | Role of the Endogenous Opioid System Underlying Modulation of Experimental Pain NCT01327326 | University of Florida | N/A |
| Completed | Comparing the Effect of Physical Therapy With Oral Appliance on Temporomandibular Disorder Related Myofascial NCT01725867 | National Taiwan University Hospital | N/A |
| Completed | Effect of Massage Therapy and Occlusal Splint Therapy on the Electromyographic Activity and Mandibular Range o NCT01874041 | University of Nove de Julho | N/A |
| Completed | A Clinical Trial of the Optimal Treatment Period and Long-term Efficacy of Functional Electrical Stimulation ( NCT01000389 | Medotech A/S | N/A |
| Completed | Analgesic Effects of LED Light on Temporomandibular Disorders. NCT01873937 | University of Sao Paulo | N/A |
| Completed | Temporomandibular Disorders and Osteoporosis NCT01029210 | University of Sao Paulo | — |
| Completed | Reliability of the Angle Measurement of the Software for Photogrammetry Postural Assessment (SAPO) NCT00873080 | Universidade Federal de Santa Maria | — |
| Completed | Stabilization Splint Treatment of TMD NCT05240703 | University of Oulu | N/A |
| Completed | Efficiency of Two Occlusal Splints on TMD Treatment of Police Officers NCT01376973 | University of Campinas, Brazil | — |
| Completed | Parafunctional Habits and Temporomandibular Disorder in Adolescents NCT01331031 | University of Nove de Julho | — |
| Completed | The Frequency Forward Head Posture in Subjects With Temporomandibular Disorder NCT00743223 | Federal University of Mato Grosso | — |
| Recruiting | The New Serial Treatment of Temporomandibular Disorders NCT00932594 | Sun Yat-sen University | N/A |