NCT07153107

R01_Pilot Jaw Muscle Phenotypes

R01_PilotStudy2_Jaw Muscle Metabolic and Brain-Derived Phenotypes of Chronic TMD Pain

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (estimated)
• Sponsor: University of Minnesota · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The proposed study will assess the effect of local heat therapy on jaw pain and jaw fatigue secondary to a teeth clenching task in chronic TMD pain cases. Researchers expect that most participants will respond to heat therapy and consequently experience reduced jaw pain and fatigue during teeth clenching. The study will assess the clinical characteristics of those participants who respond and do not respond to local heat therapy, in order to determine the common clinical characteristics for those in each response category.

Conditions

• Chronic TMD Pain
• Temporomandibular Disorder

Interventions

Type	Name	Description
OTHER	Local Heat Therapy	This will use a simple device provided to participants named "jaw bra", which is a head wrap with straps that goes around the chin and head that holds heated gel packs over the cheeks area

Timeline

• Start date: 2026-05-01
• Primary completion: 2027-01-12
• Completion: 2027-01-12
• First posted: 2025-09-03
• Last updated: 2026-03-19

Locations

1 site across 1 country: United States