NCT04066426

Efficacy of Naproxen-codeine, Naproxen+Dexamethasone, and Naproxen on Myofascial Pain

Analgesic Efficacy of Naproxen-codeine, Naproxen+Dexamethasone, and Naproxen on Myofascial Pain: A Randomized Double-blind Controlled Trial

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 200 (actual)
• Sponsor: Yuzuncu Yil University · Academic / Other
• Sex: All
• Age: 18 Years – 69 Years
• Healthy volunteers: Not accepted

Summary

Temporomandibular disorders (TMDs) are one of the most common muco-skeletal disorders, seen in the dental clinics. Many factors work together to initiate or aggravate the condition, so it is a multifactorial disorder. The etiology of TMDs may be a result of parafunctional habits such as clenching and bruxism, acute trauma to the jaw, trauma from hyperextension e.g. after a long dental treatment, joint laxity, psychological distress, occlusal disharmony like presence of high crown or free-end saddle leading to joint instability or systemic diseases such as Rheumatoid arthritis or Osteoarthritis. The aim of this study was to evaluate the effects of naproxen sodium+codeine phosphate, naproxen sodium+dexamethasone, and naproxen sodium on pain in patients complaining from temporomandibular pain.

Conditions

• Temporomandibular Disorder

Interventions

Type	Name	Description
DRUG	naproxen sodium+codeine phosphate, naproxen sodium+dexamethasone, naproxen sodium, paracetamol	NSAID, steroid, opioid, paracetamol and combinations of this drugs can be used in temporomandibular disorders.

Timeline

• Start date: 2018-03-01
• Primary completion: 2019-04-01
• Completion: 2019-07-15
• First posted: 2019-08-26
• Last updated: 2021-02-15
• Results posted: 2021-02-15

Locations

1 site across 1 country: Turkey (Türkiye)