NCT05914558

Comorbid Painful TMD Among Trigeminal Neuralgia

Comorbid Painful Temporomandibular Disorder Among Trigeminal Neuralgia Patients

• Status: Withdrawn
• Phase: —
• Study type: Observational
• Enrollment: 0 (actual)
• Sponsor: University of Minnesota · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

An observational study following up with trigeminal neuralgia patients to understand their comorbid facial pain condition, specifically temporomandibular disorder.

Detailed description

This multi-center prospective observational cohort study aims to investigate the prevalence of comorbid Temporomandibular disorders (TMD) among trigeminal neuralgia (TN) patients. Trigeminal neuralgia patients with active TN status from three clinical sites (University of Minnesota, School of Dentistry, Orofacial Pain Clinic; Mhealth Fairview, Clinical Surgical Center, Neurosurgery Clinic; John Hopkins University, Anesthesiology, and Critical Care Clinic) could enroll in this study voluntary. All the patients will be evaluated by a provider using standard clinical assessment for TN and TMD, along with validated RedCap questionnaires for TN and TMD diagnosis, and be followed up every six months for 1-2 years.

Conditions

• Trigeminal Neuralgia
• Temporomandibular Disorder
• Myofascial Pain
• Trigeminal Neuropathy

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Clinical appointment	One clinical interview and examination to confirm the diagnosis of trigeminal neuralgia and temporomandibular disorder.

Timeline

• Start date: 2022-08-01
• Primary completion: 2026-08-30
• Completion: 2026-08-30
• First posted: 2023-06-22
• Last updated: 2025-12-31

Locations

2 sites across 1 country: United States