| Recruiting | Results of Laparoscopic Appendectomy With Application of Clips Versus Ligature for Stump Closure NCT07115303 | Sohag University | N/A |
| Not Yet Recruiting | Comparison of Outcome of Open Appendectomy With and Without Transversus Abdominis Plane (TAP) Block NCT06943456 | University of Health Sciences Lahore | N/A |
| Recruiting | A Global Prospective Cohort Study on Outcomes of Appendicectomy for Appendicitis NCT06774001 | University of Birmingham | — |
| Recruiting | Early Detection of Infection Using the Fitbit in Pediatric Surgical Patients NCT06395636 | Ann & Robert H Lurie Children's Hospital of Chicago | N/A |
| Recruiting | Intravenous Ketorolac Vs. Morphine In Children With Acute Abdominal Pain NCT06160778 | University of Calgary | Phase 3 |
| Completed | Aromatherapy Versus Acupressure: Impact on Postoperative Pain and Sleep Quality in Pediatric Abdominal Surgery NCT07157501 | Mansoura University | N/A |
| Active Not Recruiting | Comparative Study of Harmonic Scalpel vs. Suture Ligation for Appendix Base During Laparoscopic Appendectomy NCT07049965 | GSVM Medical College | N/A |
| Completed | Safety & Feasibility of PERIsign System in Demonstrating Involuntary Muscle Defense as a Sign of Peritonitis i NCT06296953 | STB INN AB | N/A |
| Completed | The Effect of Kinesio Taping in Pediatric Surgery NCT06344897 | KTO Karatay University | N/A |
| Recruiting | Clinical Study of PEG Bowel Preparation in Appendectomy Patients NCT07478029 | Huaping Xie | — |
| Recruiting | Transumbilical Laparoscopic Appendectomy NCT06177418 | Necmi Kadıoğlu Hospital | N/A |
| Recruiting | Protocol Based Selective Imaging Versus Routine Computed Tomography or Ultrasound in Suspected Appendicitis NCT06083064 | Helsinki University Central Hospital | N/A |
| Completed | Effect of Modified ERAS Protocol on Clinical Outcomes in Pediatric Patients With Appendectomy NCT05962320 | Karadeniz Technical University | N/A |
| Unknown | Peri-operative Analgesia for Single-incision Laparoscopic Appendectomy NCT05773521 | University Hospital, Angers | — |
| Terminated | Sugammadex vs Neostigmine Reversal in Pediatric Appendectomy NCT05256901 | Emory University | Phase 4 |
| Recruiting | Same Day Ambulatory Appendectomy (SAMBA) NCT05691348 | Centre Hospitalier Universitaire de Nice | N/A |
| Recruiting | Complex And Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure - UCSF NCT05966454 | University of California, San Francisco | Phase 4 |
| Unknown | Intestinal Flora and Metabonomics of Appendicitis NCT06035029 | HongyiQu | — |
| Unknown | Appendectomy vs. Symptomatic Treatment in Uncomplicated Acute Appendicitis Among Pediatric Patients NCT05289713 | Helsinki University Central Hospital | N/A |
| Recruiting | PAINED: Project Addressing INequities in the Emergency Department NCT05488080 | Children's National Research Institute | N/A |
| Unknown | Mapping the Human Appendix Using Single Cell Sequencing NCT05209061 | Bispebjerg Hospital | — |
| Unknown | Laparoscopic Clipping Versus Extracorporeal Ligation in Complicated Appendicitis Upper Egypt Overview NCT05637554 | Assiut University | N/A |
| Recruiting | Complex and Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure (CASA RELAX) NCT05838248 | University of Louisville | N/A |
| Unknown | Benchtop NMR Spectroscopy for Assessment of Clinical Human Pathologies (BRANCH-P STUDY) NCT05473325 | Willows Health | — |
| Unknown | TRIAD Appendicitis Decision-making Surveys NCT05887414 | University of Washington | — |
| Unknown | Safety and Efficacy of ERAS Therapeutic Protocol for Complicated Appendicitis in Children NCT05511194 | Instituto Mexicano del Seguro Social | N/A |
| Unknown | Laparoscopic Transversus Abdominis Plane Block (LTAP) for Appendicectomy Versus Standard Port Site Treatment NCT05427266 | Royal College of Surgeons, Ireland | N/A |
| Unknown | Appendectomy and Colorectal Cancer NCT06091137 | Chinese University of Hong Kong | — |
| Completed | Evaluation of Clinical Characteristics and Pathological Findings in Patients With Suspected Appendicitis NCT06462846 | Golestan University of Medical sciences | — |
| Unknown | Peritoneal Diffusion and Efficacy of Antibiotic Therapy in Pediatric Peritonitis NCT05308849 | Central Hospital, Nancy, France | N/A |
| Unknown | Cold Therapy for Pediatric Appendectomy NCT04986397 | Boston Children's Hospital | N/A |
| Completed | The Role of Imaging in the Diagnosis of Acute Appendicitis During the COVID-19 Pandemic NCT05205681 | University College London Hospitals | — |
| Completed | Laparoscopic Versus Open Appendectomy in Pregnancy NCT05430633 | North Estonia Medical Centre | — |
| Completed | Restricted or Liberal Antibiotics After Appendectomy - Denver Health NCT05002829 | Denver Health and Hospital Authority | N/A |
| Unknown | Evaluation of the Management of Acute Appendicitis Before Emergency Department in Children: a Prospective Stud NCT04885335 | University Hospital, Limoges | — |
| Completed | Effect of Covid-19 Pandemic in Non Covid-19 Patients at the Emergency Surgical Department NCT04900233 | Hospital Italiano de Buenos Aires | — |
| Completed | Ketorolac for Moderate to Severe Abdominal Pain in Children NCT04528563 | Hamilton Health Sciences Corporation | Phase 3 |
| Completed | Ultrasound Guided Rectus Sheath Block and Transversus Abdominis Plane Block NCT04838379 | Assiut University | N/A |
| Completed | Effect of Intravenous Lignocaine Infusion on Intraoperative End Tidal Desflurane Concentration Requirements NCT06064331 | Universiti Kebangsaan Malaysia Medical Centre | N/A |
| Completed | Appendectomy by Low Impact Laparoscopy vs Routine Laparoscopy : a Randomized Prospective Monocentric Trial NCT04614519 | Centre Hospitalier Universitaire de Nice | N/A |
| Completed | Review of the Pathological Results of Appendectomy Specimens NCT05391269 | King Abdulaziz University | — |
| Terminated | Operative vs Non-Operative Management of Acute Appendicitis and Acute Cholecystitis in COVID-19 Positive Patie NCT04748120 | The Cleveland Clinic | N/A |
| Not Yet Recruiting | The Prevalence of Appendiceal Tumours in Periappendicular Abscess NCT04634448 | Turku University Hospital | N/A |
| Suspended | The Optimization of a Low-dose CT Protocol in Patients With Suspected Uncomplicated Acute Appendicitis and BMI NCT04519086 | Turku University Hospital | N/A |
| Completed | Right Iliac Fossa Treatment-Turkey Audit NCT04614649 | Gazi University | — |
| Completed | Probiotics and Antibiotic Associated Diarrhea in Pediatric Complicated Appendicitis NCT04529980 | Children's Health | N/A |
| Completed | European Society for Trauma and Emergency Surgery (ESTES) Cohort Study Snapshot Audit 2020 - Acute Appendiciti NCT04365491 | Gary Alan Bass, MD PhD | — |
| Completed | Role of Delay and Antibiotics on Perforation Rate While Waiting Appendectomy NCT04378868 | Helsinki University Central Hospital | Phase 4 |
| Completed | Studding the Implementation of ERAS Protocols in Pediatric Surgery NCT04870242 | University of Jordan | — |
| Completed | Recurrent Appendicitis Following Successful Drainage of Appendicular Abscess in Adult NCT05048745 | Zagazig University | — |
| Recruiting | Operative Versus Non-Operative Management for Appendicitis With Abscess or Phlegmon NCT04168866 | Yale University | N/A |
| Completed | the Impact of COVID-19 Pandemic on the Incidence and Outcome of Complicated Appendicitis NCT04786041 | Meir Medical Center | — |
| Completed | NOVOsyn® for Trocar Incision After Laparoscopic Appendectomy and Cholecystectomy NCT04033211 | Aesculap AG | — |
| Completed | The Impact of a Patient Education Tool for Appendicitis NCT05571566 | McGill University Health Centre/Research Institute of the McGill University Health Centre | N/A |
| Unknown | Non Absorbable Clips vs Endoloops in Laproscopic Appendicectomy NCT04094480 | Assiut University | N/A |
| Recruiting | Re-assessment of Appendicitis Evaluation During Laparoscopic Appendectomy, Peritoneal Irrigation During Laparo NCT05075252 | Niguarda Hospital | — |
| Completed | Identification of the Optimal Treatment Strategy for Complex Appendicitis in the Pediatric Population NCT04755179 | Ramon Gorter | — |
| Completed | Clinical Trial for a Outpatient Clinical Management of Urgent Laparoscopic Appendectomy NCT05401188 | HJ23 | N/A |
| Completed | EFFECT OF USING SAME DERMATOME LİNE FOR ALL PORT SİTES IN LAPAROSCOPIC APPENDECTOMY IN ACUTE APANDICITIS NCT03792802 | Fatih Sultan Mehmet Training and Research Hospital | N/A |
| Withdrawn | Once Daily Metronidazole for Perforated Appendicitis NCT02561117 | Ahmed Nasr | Phase 4 |
| Unknown | A Randomized Controlled Trial on Wound Irrigation in Open Appendectomy. NCT04332809 | Mansoura University | N/A |
| Completed | Role of Wound Irrigation After Appendectomy NCT03773224 | Mansoura University | N/A |
| Completed | (D)Elayed vs. (E)Arly (L)Aparoscopic (A)Ppendectom(Y) NCT03524573 | Queen's University | N/A |
| Completed | Quadratus Lumborum Block Versus Transversus Abdominis Plane Block in Children Undergoing Laparoscopic Appendic NCT04031196 | Zagazig University | N/A |
| Completed | Laparoscopic Appendectomy Performed by Junior SUrgeonS: Impact of 3D Visualization on Surgical Outcome NCT03770897 | Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia | N/A |
| Completed | Grey Zone Appendicitis: Role of Blood Test Biomarkers to Detect Early Appendicitis and to Decrease the Inciden NCT04271826 | Zagazig University | N/A |
| Completed | Acute Appendicitis: Active Observation With and Without Antibiotics NCT03985514 | Göteborg University | Phase 4 |
| Unknown | Pain and Discomfort After Appendectomy in Children NCT03791229 | Sakarya University | — |
| Completed | Impact of SARS-Cov2 Pandemic on Severity of Perioperative Complications in Patients Undergoing Appendectomy NCT05178251 | Central Hospital, Nancy, France | — |
| Completed | Abdominal Drainage During Appendicectomy - Resources Down the Drain: A Retrospective Cohort Study NCT04163211 | The Whittington Hospital NHS Trust | — |
| Unknown | CT Carcinogenic Risk in Patients With Appendicitis NCT03776435 | Seoul National University Bundang Hospital | — |
| Withdrawn | A Retrospective Study of the Feasibility of Ambulatory Appendicectomy for Acute Appendicitis (Based on Data Fr NCT02894086 | Centre Hospitalier Universitaire, Amiens | — |
| Completed | Explanations for Negative Laparoscopic Appendectomies and Normal Laparoscopies NCT03349814 | Herlev Hospital | — |
| Terminated | Raja Isteri Pengiran Anak Saleha Appendicitis Treatment Without Operation NCT03169114 | Raja Isteri Pengiran Anak Saleha Hospital | N/A |
| Unknown | Pediatric Appendicitis Risk Calculator (pARC) in Children With Appendix Ultrasounds NCT03522233 | Children's Hospitals and Clinics of Minnesota | — |
| Withdrawn | Narcotic vs. Non-narcotic Pain Regimens After Pediatric Appendectomy NCT03528343 | University of Utah | Phase 1 / Phase 2 |
| Completed | Finding Evidence to Treat Or Reassure in Appendicitis (FETOR) NCT03248102 | The Leeds Teaching Hospitals NHS Trust | N/A |
| Unknown | Solo and Non-solo Approach for Laparoscopic Appendectomy (SOLOAP) NCT03224364 | Say-June Kim | N/A |
| Completed | Optimal Care of Complicated Appendicitis NCT03159754 | University of Michigan | Phase 4 |
| Completed | EHR-based Decision Support for Pediatric Acute Abdominal Pain in Emergency Care NCT02633735 | HealthPartners Institute | N/A |
| Completed | Implementation of 23 Hour Surgery Model in a Tertiary Hospital NCT04142203 | Kuopio University Hospital | — |
| Completed | Appendicitis During the National Lockdown During the COVID-19 Pandemic NCT04407117 | Claus Anders Bertelsen, PhD, MD | — |
| Completed | The Safety and Pharmacokinetics of Intraperitoneal Administration in Patients Undergoing Appendectomy for Unco NCT03046758 | Herlev Hospital | Phase 2 |
| Completed | Comparison of Medical and Surgical Treatment of Uncomplicated Acute Appendicitis in Children NCT02991937 | NYU Langone Health | Phase 4 |
| Unknown | Initial Non-operative Treatment Strategy Versus Appendectomy Treatment Strategy for Simple Appendicitis in Chi NCT02848820 | Ramon Gorter | Phase 4 |
| Completed | Polymer Clips Vs Endoloop for Appendicular Stump Ligation NCT03591419 | Services Hospital, Lahore | N/A |
| Completed | Influence of the Different Ways of Appendix Stump Closure on Patient Outcome in Laparoscopic Appendectomy NCT02941640 | University Clinical Center Tuzla | N/A |
| Completed | Children's Surgery in Sub-Saharan Africa NCT03185637 | King's College London | — |
| Completed | Conservative Versus Operative ManageMent of Acute Uncomplicated Appendicitis NCT02916134 | Beaumont Hospital | N/A |
| Unknown | A Trial to Assess the Efficacy and Safety of Morinidazole in Patients With Appendicitis NCT03380793 | Jiangsu Hansoh Pharmaceutical Co., Ltd. | Phase 4 |
| Unknown | Polymer Clips Versus Endoloops for Closure of the Appendiceal Stump During Emergency Laparoscopic Appendicecto NCT02726152 | National Health Service, United Kingdom | N/A |
| Completed | Postoperative Complications After Appendectomy NCT03119740 | Kepler University Hospital | — |
| Completed | Point of Care 3D Ultrasound for Various Applications: A Pilot Study NCT02831556 | Duke University | — |
| Unknown | Non-operative Management for Appendicitis in Children NCT02795793 | Sydney Children's Hospitals Network | N/A |
| Completed | The Comparison of Outcomes of Antibiotic Drugs and Appendectomy (CODA) Trial NCT02800785 | University of Washington | N/A |
| Completed | Acute Abdomen in Kawasaki Disease NCT03902262 | National Institute of Pediatrics, Mexico | — |
| Completed | DIAgnostic iMaging or Observation in Early Equivocal appeNDicitis NCT02742402 | Helsinki University Central Hospital | N/A |
| Completed | Appendectomy Versus Non-Operative Treatment For Acute Non-Perforated Appendicitis in Children NCT02687464 | Children's Mercy Hospital Kansas City | N/A |
| Unknown | The Effect of Breastfeeding on the Development of Appendicitis in Adults NCT02679547 | Sisli Hamidiye Etfal Training and Research Hospital | — |
| Unknown | Nebulized Analgesia for Laparoscopic Appendectomy Trial NCT02624089 | McGill University Health Centre/Research Institute of the McGill University Health Centre | Phase 1 / Phase 2 |
| Unknown | Irrigation Versus Suction in Complicated Acute Appendicitis NCT02688244 | Hospital Universitario Virgen de la Arrixaca | N/A |
| Completed | Point of Care 3D Ultrasound for Pediatric Appendicitis: a Pilot Study NCT02507674 | Duke University | — |
| Completed | CT Dose Simulation Study for Appendicitis NCT02556983 | Seoul National University Bundang Hospital | — |
| Unknown | Evaluation of Local Anesthetic at Incision Site NCT02483689 | Valley Anesthesiology Consultants | N/A |
| Completed | The Optimization of a Low-dose Computed Tomography Protocol in Patients With Suspected Uncomplicated Acute App NCT02533869 | Turku University Hospital | N/A |
| Terminated | Impact of Oral Contrast in the Large Intestine on the Recognition of Appendix NCT02497183 | HaEmek Medical Center, Israel | N/A |
| Completed | The Circulating Fibrocyte - a Novel and Accurate Biomarker in Diagnosing Acute Appendicitis in Adults NCT03988660 | University Hospital of Limerick | — |
| Completed | Appendicectomy Skin Closure Technique: Changing Paradigms (ASC) NCT02625987 | María Valeria Jiménez Baez | Phase 4 |
| Unknown | Laparoscopic Appendectomy for Uncomplicated Appendicitis: Does Antimicrobial Prophylaxis Really Matter? NCT02404064 | HaEmek Medical Center, Israel | N/A |
| Completed | a Retrospective Observational Study Comparing Outcomes of Retrocaecal Appendicitis With Non-retrocaecal Append NCT05315869 | Faculty Hospital Kralovske Vinohrady | — |
| Withdrawn | Antimicrobial Stewardship in Pediatric Surgery NCT02270996 | Alberta Children's Hospital | — |
| Completed | Choose the Best Concentration of Ropivacaine on TAP Block for Open Appendectomy in Children NCT03005808 | Hospital Infantil Albert Sabin | Phase 4 |
| Unknown | Domestic Surgical Robot Clinical Study NCT02752698 | The Third Xiangya Hospital of Central South University | N/A |
| Completed | Practical Advantages of Single-port Over Three-port Laparoscopic Appendectomy in Children NCT03106467 | Hallym University Medical Center | N/A |
| Unknown | Multi-institutional Trial of Non-operative Management of Appendicitis NCT02271932 | Nationwide Children's Hospital | — |
| Terminated | Non-operative Management of Pediatric Appendicitis With an Appendicoltih NCT02189668 | Peter Minneci | N/A |
| Unknown | Improvement of Appendix Identification and Appendicitis Diagnosis in us After Administration of Oral Contrast NCT02194140 | Hillel Yaffe Medical Center | N/A |
| Completed | Randomized Controlled Trial of a Patient Activation Tool in Pediatric Appendicitis (Antibiotics Alone vs. Appe NCT02110485 | Peter Minneci | N/A |
| Completed | Low vs. Standard Dose CT for Appendicitis Trial NCT01925014 | Kyoung Ho Lee, MD | N/A |
| Terminated | The Laparoscopic Appendicitis Score; a Multicenter Validation Study NCT02029781 | University Medical Center Groningen | N/A |
| Unknown | Comparative Study of Microwave Radiometry and Ultrasonography for the Diagnosis of Acute Appendicitis NCT02108340 | Hippocration General Hospital | N/A |
| Completed | Ultrasound-guided Abdominal Wall Nerve Blockade in Laparoscopic Surgery for Acute Appendicitis. NCT01825863 | Bispebjerg Hospital | N/A |
| Completed | Comparative Study of Polymetric Clips (Hem-o-Lok) Versus Historical Endoscopic Staplers for Laparoscopic Appen NCT01830387 | Duke University | — |
| Terminated | Is Interval Appendectomy Necessary? NCT01853683 | Children's Hospital of Eastern Ontario | N/A |
| Completed | Influence of Hospital Volume on Mortality and Short-term Postoperative Outcomes in Uncomplex General Surgery i NCT07022665 | Cantonal Hospital of St. Gallen | — |
| Unknown | Non-operative Management of Early Appendicitis in Children NCT01718275 | Peter Minneci | — |
| Terminated | Transversus Abdominis Plane (TAP) Versus Local Anesthetic for Lap Appendectomies NCT01575028 | Nationwide Children's Hospital | Phase 2 |
| Completed | Antibiotic Treatment Alone for Acute Simple Appendicitis in Children NCT01356641 | Ramon R. Gorter | N/A |
| Completed | Laparoscopic Versus Open Appendectomy? Let the Patient Decide NCT01738750 | University of Utah | N/A |
| Withdrawn | Importance of Peritoneal Free Fluid Cultures in Acute Appendicitis NCT01953289 | Universitaire Ziekenhuizen KU Leuven | — |
| Unknown | The Hasselt APPendicitis Immunology and Environmental Cohort STudy NCT02391675 | Hasselt University | — |
| Unknown | Single Incision Versus Conventional 3-Port Laparoscopic Appendectomy NCT01567098 | Hospital Authority, Hong Kong | N/A |
| Unknown | The Value of Pancreatic Stone Protein in Predicting Acute Appendicitis NCT01610193 | University of Zurich | — |
| Completed | Conservative Treatment of Acute Appendicitis in Children NCT01572558 | Karolinska University Hospital | N/A |
| Completed | Perioperative Pain Management of Pediatric Appendectomy Patients NCT02580487 | Kuopio University Hospital | — |
| Unknown | Active Versus Non Active Drainage for the Treatment of Infected Intra-abdominal Collection NCT01513421 | Centre Hospitalier Universitaire Vaudois | — |
| Completed | Are Post-operative Antibiotics Indicated in Simple Appendicitis? NCT01420367 | Monash University | N/A |
| Completed | A Prospective Study of The Complement Depletion in Patients With Severe Abdominal Sepsis NCT01568853 | Jinling Hospital, China | N/A |
| Completed | TICAP - Titanium Clips for Appendiceal Stump Closure NCT01734837 | Aesculap AG | — |
| Completed | A Comparison of UGBRS Block and Local Infiltration NCT02352519 | Baylor College of Medicine | Phase 4 |
| Completed | Inflammatory Response in Appendicitis NCT01718171 | Cirujanos la Serena | — |
| Completed | Laparoscopic Management of Periappendicular Abscess NCT01283815 | Helsinki University Central Hospital | Phase 2 |
| Terminated | A Safety and Tolerability Study of Doripenem Compared With Meropenem in Children Hospitalized With Complicated NCT01110382 | Janssen Research & Development, LLC | Phase 3 |
| Completed | Pediatric Appendicitis Pathway Study NCT01192620 | Oregon Health and Science University | — |
| Completed | Open Appendectomy Versus Laparoscopic Appendectomy NCT01260064 | Bakirkoy Dr. Sadi Konuk Research and Training Hospital | N/A |
| Terminated | Single-incision Laparoscopic (SILS) Versus Conventional Laparoscopic Appendectomy for the Treatment of Acute A NCT00997516 | University of California, San Francisco | N/A |
| Completed | Diagnostic Performance of C Reactive Protein and Delta CRP in Acute Appendicitis NCT02730585 | University of Monastir | — |
| Completed | APPEndicitis and Laparoscopic Criteria; APPEL Study NCT01054417 | University Medical Center Groningen | — |
| Completed | Safety and Efficacy Study of Single Port Laparoscopic Appendectomy in Acute Appendicitis NCT01007318 | Kyunghee University Medical Center | N/A |
| Withdrawn | Hybrid Transvaginal-Transabdominal Endoscopic Surgery NCT01039129 | St. Luke's-Roosevelt Hospital Center | N/A |
| Completed | A Randomised Controlled Trial on LESS Versus Conventional Laparoscopic Appendicectomy. NCT01203566 | Chinese University of Hong Kong | Phase 3 |
| Completed | Single Incision Versus Conventional Laparoscopic Appendectomy NCT01515293 | Hospital Universitario Virgen de la Arrixaca | Phase 3 |
| Completed | Diagnosis of Acute Appendicitis: Low-dose Computed Tomography (CT) Versus Standard-dose CT NCT00913380 | Seoul National University Bundang Hospital | Phase 3 |
| Terminated | Structured Management of Patients With Suspicion of Appendicitis Using a Clinical Score and Selective Imaging NCT00971438 | Ryhov County Hospital | N/A |
| Completed | Single Incision Laparoscopic Surgery (SILS) Versus Laparoscopic Appendectomy NCT00981136 | Children's Mercy Hospital Kansas City | N/A |
| Completed | Single Incision Laparoscopic Appendectomy in the Community Utilizing Conventional Instruments NCT00925145 | University of British Columbia | — |
| Terminated | Perforated Appendicitis With Delayed Presentation NCT01068288 | The Hospital for Sick Children | N/A |
| Completed | Wound Healing After Emergency Appendicectomy NCT00913445 | Tampere University Hospital | Phase 4 |
| Completed | Diagnostic Accuracy of Serum Bilirubin in the Prediction of Perforated Appendicitis NCT01698099 | University Hospital Tuebingen | — |
| Completed | Colonic Resections in Patients With Suspected Appendicitis NCT00888888 | Cirujanos la Serena | — |
| Completed | Study for a Rational Management of Appendicitis in Children NCT01067937 | Nantes University Hospital | N/A |
| Completed | Comparative Effectiveness of Intravenous v. Oral Antibiotic Therapy for Serious Bacterial Infections NCT02311452 | Children's Hospital of Philadelphia | — |
| Unknown | Trial on Postoperative Outcomes According to the Number of Trocar During Laparoscopic Appendectomy NCT00816933 | The Catholic University of Korea | Phase 1 |
| Completed | Effect of Pain Control on the Diagnosis of Acute Appendicitis on the Diagnostic Accuracy of General Surgeon NCT00783016 | Seoul National University Hospital | Phase 4 |
| Completed | Transvaginal Appendectomy NCT00806429 | Yale University | N/A |
| Completed | Magnetic Resonance Imaging (MRI) of Appendicitis in Children NCT00723788 | Children's National Research Institute | N/A |
| Completed | NOTES Transvaginal Cholecystectomy and Appendectomy NCT00552162 | Hadassah Medical Organization | N/A |
| Withdrawn | Study on the Difference of Axilo-rectal Temperature in Appendicitis NCT00674726 | Cirujanos la Serena | — |
| Completed | Diagnostic Value of Procalcitonin in Patients With Acute Appendicitis NCT00630071 | Ruhr University of Bochum | — |
| Unknown | Minimally Invasive Surgery: Using Natural Orifice Translumenal Endoscopic Surgery (NOTES) NCT00531219 | University of California, San Diego | — |
| Completed | Comparative Study of Laparoscopic Versus Open Appendectomy in Children NCT00554008 | Oregon Health and Science University | N/A |
| Completed | Minimally Invasive Surgery: Using Natural Orfices NCT00530998 | University of California, San Diego | — |
| Completed | Single Incision Laparoscopy NCT00616616 | University of California, San Diego | N/A |
| Withdrawn | Cefoperazone/Sulbactam In The Treatment Of Serious Intra-Abdominal And Hepatobiliary Infections. NCT00463762 | Pfizer | — |
| Completed | Emergency Department CT Scanning for Appendicitis NCT00734825 | WellSpan Health | N/A |
| Completed | Study of Conservative Versus Surgical Treatment of Appendicitis NCT00469430 | Göteborg University | Phase 2 |
| Completed | Wound Infection Alexis Wound Retractor NCT00323453 | Santa Barbara Cottage Hospital | N/A |
| Completed | Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infect NCT00230971 | Wyeth is now a wholly owned subsidiary of Pfizer | Phase 4 |
| Completed | Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infect NCT00195351 | Wyeth is now a wholly owned subsidiary of Pfizer | Phase 4 |
| Completed | Doripenem in the Treatment of Complicated Intra-Abdominal Infections NCT00210938 | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | Phase 3 |
| Completed | Doripenem in the Treatment of Complicated Intra-Abdominal Infections NCT00229060 | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | Phase 3 |
| Completed | Antibiotic Therapy Versus Appendectomy for Acute Appendicitis NCT00135603 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Morphine Analgesia in Patients With Acute Appendicitis NCT00477061 | Tehran University of Medical Sciences | Phase 4 |
| Completed | CT Scan Using IV Contrast Alone for Pediatric Appendicitis NCT00716703 | University of Rochester | N/A |
| Terminated | A Study Comparing Safety and Efficacy of Levofloxacin and Metronidazole Versus Piperacillin/Tazobactam in Trea NCT00236912 | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | Phase 4 |
| Unknown | Appendicitis With Medical Treatment NCT00172822 | National Taiwan University Hospital | — |
| Completed | A Comparison of Appendicectomy Outcomes in Children Between Paediatric and General Surgical Centres in Scotlan NCT02047786 | University of Edinburgh | — |
| Completed | The Hospital Volume Relationship in Appendicectomy Outcomes NCT02018016 | University of Edinburgh | — |
| Completed | Geographic Influences on Appendicectomy Outcomes NCT02017951 | University of Edinburgh | — |
| Completed | Is Acute Appendicitis Still a Clinical Diagnosis? NCT04477824 | Claus Anders Bertelsen, PhD, MD | — |
| Completed | Evaluation of Pressure Algometry in the Clinical Assessment of Acute Abdominal Pain in Children NCT04688463 | University of Manitoba | — |
| Completed | Open Versus Laparoscopic Appendectomy NCT00908804 | North Karelia Central Hospital | N/A |