Clinical Trials Directory

Trials / Completed

CompletedNCT05315869

a Retrospective Observational Study Comparing Outcomes of Retrocaecal Appendicitis With Non-retrocaecal Appendicitis

Retrocaecal Appendicitis: Risk Factor for Perioperative Complications?

Status
Completed
Phase
Study type
Observational
Enrollment
754 (actual)
Sponsor
Faculty Hospital Kralovske Vinohrady · Other Government
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

A retrospective observational study investigating whether retrocecal appendicitis associated with worse operative and postoperative outcomes than non-retrocecal appendicitis.

Detailed description

Acute appendicitis is the most common cause of acute abdomen requiring acute surgery. The prevalence of the retrocaecal position of the appendix varies significantly between studies from 14 to 36%. Appendectomy of a retrocecal appendix is generally considered to be more demanding procedure than appendectomy of appendices in other positions. The aim of this study is to investigate whether retrocaecal appendicitis is associated with a higher rate of perioperative complications and delayed diagnosis when compared with the other positions. A retrospective analysis of prospectively collected data of patients undergoing surgery for signs of acute appendicitis from January 2015 to April 2020 at the University Hospital Kralovske Vinohrady. Two groups of patients were be formed: the retrocaecal group and the non-retrocaecal group. The following data were recorded: sex, age, body mass index, length of hospital stay, abdominal drain placement, length of surgery, surgical approach (laparoscopic, open or converted), operative finding (normal appendix or catarrhal, phlegmonous, gangrenous, or perforated appendicitis), position of the appendix (retrocaecal or non-retrocaecal positions), histopathological findings (acute inflammation, chronic inflammation, appendiceal tumour or normal appendix), 30-day postoperative complications, 30-day postoperative mortality, symptoms (abdominal pain, nausea, vomiting, diarrhoea, body temperature above 37 degrees celsius, urological complaints and gynaecological complaints), duration of symptoms (from onset to surgery), serious comorbidities and diabetes mellitus.

Conditions

Interventions

TypeNameDescription
PROCEDUREAppendectomySurgical procedure for removal of the appendix

Timeline

Start date
2015-01-01
Primary completion
2020-04-01
Completion
2020-05-01
First posted
2022-04-07
Last updated
2022-04-07

Locations

1 site across 1 country: Czechia

Source: ClinicalTrials.gov record NCT05315869. Inclusion in this directory is not an endorsement.