| Not Yet Recruiting | First Appendectomy Using Revolve Surgical Robotic Arm NCT07455487 | Unity Health Toronto | N/A |
| Recruiting | Out-patiente Management for Gangrenous Acute Appendicitis: The PENDI-CSI II Randomized Clinical Trial. NCT07521969 | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | N/A |
| Recruiting | Prevention of Postoperative Hernias in Emergency Surgery NCT06815822 | Jan Kochanowski University | — |
| Recruiting | Enhanced Recovery After Surgery (ERAS) for Complicated Appendicitis NCT06948071 | Cedars-Sinai Medical Center | N/A |
| Recruiting | The Impact of a Diagnostic Strategy for Acute Appendicitis in Children With Acute Abdominal Pain in Primary Ca NCT06762275 | University Medical Center Groningen | N/A |
| Completed | Capillary Leak Index as a Prognostic Indicator for Post-Operative Abdominal Sepsis in Critically Ill Patients NCT06901544 | Ain Shams University | — |
| Recruiting | Early Detection of Infection Using the Fitbit in Pediatric Surgical Patients NCT06395636 | Ann & Robert H Lurie Children's Hospital of Chicago | N/A |
| Completed | Safety & Feasibility of PERIsign System in Demonstrating Involuntary Muscle Defense as a Sign of Peritonitis i NCT06296953 | STB INN AB | N/A |
| Recruiting | Clinical Study of PEG Bowel Preparation in Appendectomy Patients NCT07478029 | Huaping Xie | — |
| Recruiting | Low-dose Contrast Media for Low-kVp Abdomen CT NCT05878665 | Bohyun Kim | N/A |
| Unknown | Laparoscopic Versus Open Appendectomy Prospective Randomized Control Study NCT05611489 | Abanoub Atif Fawzy | N/A |
| Completed | Comparison of Ketorolac at Three Doses in Children With Acute Pain NCT05641363 | Hamilton Health Sciences Corporation | Phase 3 |
| Completed | A Comparative Study of CCI, EmSFI, and FTRST Scoring Systems NCT06943924 | Dr. Lutfi Kirdar Kartal Training and Research Hospital | — |
| Completed | Efficacy of LigaSure Versus Harmonic Scalpel US in Laparoscopic Appendectomy in Management of Acute Appendicit NCT07091110 | Zagazig University | — |
| Unknown | Diagnostic Importance of the Circulating Human Leucine-rich α-2-glycoprotein in Acute Appendicitis in Pediatri NCT05093660 | KBC Split | — |
| Completed | Online Field Test of an Appendicitis Decision Support Tool NCT05219786 | University of Washington | N/A |
| Completed | Evaluation of One Day Discharge After Laparoscopic Appendectomy for Uncomplicated Appendicitis in Children. NCT05095987 | Miro Jukić | N/A |
| Completed | Low vs Medium Pressure Pneumoperitoneum NCT04949659 | University Children's Hospital, Zurich | N/A |
| Completed | Surgical Site Infiltration Using Ketamine Versus Bupivacaine for Analgesia in Post-operative Appendectomy Oper NCT05097118 | Sohag University | EARLY_Phase 1 |
| Completed | TAP Block Versus Local Anesthesia Wound Infiltration for Postoperative Pain Relief After Appendicectomy in Chi NCT04969133 | Centre Hospitalier Universitaire de Besancon | N/A |
| Completed | Laparoscopically Guided Rectus Sheath Block in Pediatric Appendicitis NCT04717193 | University of Alberta | Phase 2 |
| Unknown | Short Post-operative Antibacterial Therapy in Complicated Appendicitis: Oral Versus Intravenous NCT04947748 | North Estonia Medical Centre | N/A |
| Completed | Right Iliac Fossa Treatment-Turkey Audit NCT04614649 | Gazi University | — |
| Unknown | Transumbilical Laparoscopy-assisted Appendectomy NCT04485247 | Myongji Hospital | N/A |
| Withdrawn | Contrast-Enhanced Ultrasound Diagnosis of Acute Appendicitis NCT03295656 | Boston Children's Hospital | Phase 1 |
| Unknown | Role of Duplex Doppler in Accurate Diagnosis of Appendicitis NCT04130074 | abdelRahman Ahmad abdAllah | — |
| Unknown | Polymerase Chain Reaction (PCR) and Cultivation of the Peritoneal Fluid at Operation for Appendicitis and Post NCT04713527 | University of Southern Denmark | — |
| Completed | Transversus Abdominis Plane Block Versus Quadratus Lumborum Block for Pain Management in Laparoscopic Appendec NCT05310266 | Bakirkoy Dr. Sadi Konuk Research and Training Hospital | N/A |
| Completed | Outcome and Quality of Life in Obese Patients Underwent Laparoscopic vs. Open Appendectomy NCT05434988 | Suez Canal University | — |
| Unknown | Management of Acute Appendicitis at District General Hospital NCT04707339 | Princess Alexandra Hospital NHS Trust | — |
| Unknown | Investigation of Oxidative Stress in Appendectomy - Open Versus Laparoscopic in Childhood and Adolescence NCT03723642 | Medical University of Graz | N/A |
| Completed | Comparison of Open and Laparoscopic Appendectomy in Pediatric Population NCT06363318 | King Edward Medical University | N/A |
| Completed | Clinical Trial for a Outpatient Clinical Management of Urgent Laparoscopic Appendectomy NCT05401188 | HJ23 | N/A |
| Completed | Review of Efficacy of Used ultraSonic Energy Device NCT04226482 | University of Split, School of Medicine | N/A |
| Unknown | Evaluating the Safety and Efficacy of a Outpatient Appendectomy NCT04464382 | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | N/A |
| Completed | Analysis of Endoloops, Endostaples and Endoclips for Closing the Appendiceal Stump During Laparoscopic Appende NCT04083313 | University Hospital Dubrava | N/A |
| Completed | Laparoscopic Appendectomy Performed by Junior SUrgeonS: Impact of 3D Visualization on Surgical Outcome NCT03770897 | Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia | N/A |
| Completed | Wound Infiltration With Local Anesthetic Agent for Laparoscopic Appendectomy in Adult NCT03481517 | National Taiwan University Hospital | Phase 4 |
| Unknown | Imaging and Histopathological Examination for Evaluation of Pediatric Appendicitis Score NCT03171662 | Assiut University | N/A |
| Completed | Feasability of Ambulatory Appendicectomy NCT03186105 | Fondation Lenval | N/A |
| Unknown | Leave or Laparoscopic Appendectomy With Normal Findings - a Regional Cohort Study NCT06000020 | Nordsjaellands Hospital | — |
| Completed | Outcome of Elderly Patients With Appendicitis NCT04791657 | Gulhane Training and Research Hospital | — |
| Completed | Appendicitis in Adults and Children in France-A Prospective Study by the French Surgical Association Multicent NCT04214340 | Association Francaise de Chirurgie | — |
| Completed | Value of Ultrasound and Computed Tomography in the Diagnosis of Acute Appendicitis With Histopathology as Gold NCT05070000 | KU Leuven | — |
| Completed | Are Cesarean Section and Appendectomy in Pregnancy and Puerperium Interrelated? NCT04876547 | Amasya University | — |
| Completed | a Retrospective Observational Study Comparing Outcomes of Retrocaecal Appendicitis With Non-retrocaecal Append NCT05315869 | Faculty Hospital Kralovske Vinohrady | — |
| Completed | Appendectomy During Pregnancy and Child Development NCT05759351 | Clinical Hospital Centre Zagreb | — |
| Completed | New Technique For Laparoscopic Appendicectomy NCT04751214 | Israel De Alba Cruz | — |