NCT06948071

Enhanced Recovery After Surgery (ERAS) for Complicated Appendicitis

Enhanced Recovery Protocol for Acute, Complicated Appendicitis After Laparoscopic Appendectomy: An Exploratory Pilot Study

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Cedars-Sinai Medical Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The exploratory objective of this pilot study is to evaluate the feasibility and safety of an enhanced recovery protocol that will allow adult patients to be discharged to home on an oral antibiotic regimen for three days following a laparoscopic appendectomy for complicated appendicitis. Feasibility will be determined by high compliance and adherence of patients to the postoperative instructions, while safety will be assessed by the incidence of postoperative infectious complications and requirement for re-admission.

Conditions

• Appendicitis Acute
• Appendicitis Perforated
• Appendicitis With Perforation
• Appendicitis Suppurative
• Appendicitis Gangrenous

Interventions

Type	Name	Description
OTHER	Discharge on oral antibiotics	Patients will be discharged to home on an oral antibiotic regimen for 3 days instead of being admitted for intravenous antibiotics.

Timeline

• Start date: 2025-04-21
• Primary completion: 2025-12-31
• Completion: 2026-02-28
• First posted: 2025-04-29
• Last updated: 2025-04-29

Locations

1 site across 1 country: United States