NCT06083064

Protocol Based Selective Imaging Versus Routine Computed Tomography or Ultrasound in Suspected Appendicitis

Protocol Based Selective Imaging Versus Routine Computed Tomography or Ultrasound in Suspected Appendicitis (PROSECCO)

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 900 (estimated)
• Sponsor: Helsinki University Central Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to compare protocol based selective imaging to routine imaging in adult patients with suspected appendicitis. The main question\[s\] it aims to answer are: * Does protocol based selective imaging using clinical scoring affect clinical outcome? * Does protocol based selective observation combined with score based selective imaging affect clinical outcome? Participants will be randomized into three groups: * Selective imaging based on Adult Appendicitis Score * Selective observation based on Appendicitis Severity Score combined with selective imaging based on Adult Appendicitis Score * Routine imaging using ultrasound and/or computed tomography Researchers will compare selective imaging groups separately with routine imaging to see if number of negative appendectomies or number of complicated appendicitis is not significantly increased.

Conditions

• Appendicitis

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Abdominal imaging	Abdominal ultrasound and/or abdominal CT
OTHER	Score based selective abdominal imaging	Abdominal imaging is done selectively based on Adult Appendicitis Score
OTHER	Score based selective observation combined with selective abdominal imaging	Observation based on Appendicitis Severity Score combined Adult Appendicitis Score based selective abdominal imaging

Timeline

• Start date: 2023-11-15
• Primary completion: 2026-12-31
• Completion: 2028-12-31
• First posted: 2023-10-13
• Last updated: 2025-03-12

Locations

3 sites across 1 country: Finland