NCT03776435

CT Carcinogenic Risk in Patients With Appendicitis

Carcinogenic Risk of CT in Patients With Appendicitis

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 1,000,000 (estimated)
• Sponsor: Seoul National University Bundang Hospital · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to compare the incidence rate of leukemia between CT-exposed and CT-unexposed group in patients who underwent appendectomy in South Korea.

Detailed description

South Korea has a single-payer healthcare system, administered by National Health Insurance Service (NHIS). As healthcare providers in South Korea need to claim reimbursement to NHIS for the vast majority of diagnostic and therapeutic procedures, the NHIS database enabled us to construct a large cohort who did or did not undergo CT for appendicitis. The purpose of this study is to compare the incidence rate of cancer between CT-exposed and CT-unexposed group in patients who underwent appendectomy in South Korea.

Conditions

• Computed Tomography
• Carcinogenesis
• Radiation Exposure
• Appendicitis

Interventions

Type	Name	Description
RADIATION	Abdomen CT	Patients are divided into CT-exposed or unexposed group according to the presence of claims codes of abdominopelvic CT conducted within seven days before and after appendectomy. The seven-day threshold is arbitrarily determined considering the delay in the diagnosis of appendicitis and the postoperative examination for surgical complication.

Timeline

• Start date: 2018-01-15
• Primary completion: 2020-12-15
• Completion: 2021-05-15
• First posted: 2018-12-14
• Last updated: 2020-02-17

Locations

1 site across 1 country: South Korea