Xerostomia

142 registered clinical trials studyying Xerostomia — 13 currently recruiting.

Status	Trial	Sponsor	Phase
Withdrawn	Sparing Parotid Ducts Via MRI Sialography for Reduced Patient Reported Xerostomia NCT06276946	UNC Lineberger Comprehensive Cancer Center	N/A
Not Yet Recruiting	Effect of Enzymatic-Containing Mouth Spray (Oral7®) on Xerostomia Symptoms, Salivary Flow Rate, and Oral Healt NCT06984848	ZAINAB MAT YUDIN	N/A
Active Not Recruiting	Photodynamic Treatment as Part of Oral Healthcare on Persons With Sjögren's Syndrome NCT06877546	Koite Health Oy	N/A
Not Yet Recruiting	Efficacy of the Vacucis Candida® Autovaccine NCT05289375	University of Santiago de Compostela	N/A
Active Not Recruiting	Longitudinal Oral Health Changes After Head and Neck Radiotherapy NCT07394842	Ain Shams University	—
Recruiting	Acupressure on Xerostomia in Head and Neck Cancer Patients NCT06465628	The University of Hong Kong	N/A
Recruiting	Dose-Escalation Trial of Mesenchymal Stromal Cells in Patients With Medical Xerostomia NCT06392711	University of Wisconsin, Madison	Phase 1
Active Not Recruiting	Dry Mouth Toothpaste Study - Comparing Two Toothpastes With Arginine NCT06365047	Tufts University	Phase 3
Not Yet Recruiting	Diagnostic Interest of the Buccal Schirmer Test in Xerostomia During Sjögren's Syndrome: XERODIAG NCT06530940	University Tunis El Manar	—
Not Yet Recruiting	Artificial Saliva Containing Cumin and Ginger Extract in Head and Neck Cancer Patients With Xerostomia NCT05872464	Chulalongkorn University	N/A
Not Yet Recruiting	Artificial Saliva Containing Cumin and Ginger Extract in Hemodialysis Patients With Xerostomia NCT06476223	Chulalongkorn University	N/A
Active Not Recruiting	Effect of Whitening Agent With Emulsion Gel in Saliva and Halitosis NCT06194123	Tufts University	N/A
Completed	The Efficacy of Thyme Honey Mouth Rinse on Polypharmacy-induced Xerostomia NCT06201923	Ain Shams University	Phase 4
Not Yet Recruiting	Safety and Potential Effect of Innovative Cell-based Therapy Using Adipose-derived Stromal Vascular Fraction i NCT05857358	Assistance Publique Hopitaux De Marseille	Phase 1 / Phase 2
Completed	Efficacy of Transcutaneous Electrical Nerve Stimulation in Patients With Xerostomia (ETENX) NCT06708195	Universidad de Murcia	N/A
Recruiting	An Investigation Into Taste Problems Associated With Xerostomia in Patients With Advanced Cancer NCT06287294	Our Lady's Hospice and Care Services	—
Unknown	Aloe Vera Versus Thyme Honey Mouthwash in Management of Xerostomia in Type 2 Diabetics NCT05885906	Ain Shams University	Phase 3
Active Not Recruiting	Study Transplanting Bone Marrow Cells Into Salivary Glands to Treat Dry Mouth Caused by Radiation Therapy NCT05820711	University of Wisconsin, Madison	Phase 1
Recruiting	A Mouth Education Program for Dry Mouth NCT05964959	Leiden University Medical Center	N/A
Completed	The Use of Photobiomodulation in the Treatment of Oral Complaints of Long COVID-19.A Randomized Controlled Tri NCT05760092	University of Nove de Julho	Phase 2
Unknown	Effectiveness of Extraoral Photobiomodulation in Management of Oral Adverse Effects in Patients Undergoing HSC NCT05759975	Federal University of Rio Grande do Sul	N/A
Completed	The Effect of Chewing Gum, Exercises of the Tongue, Lip, Jaw on Salivation, Xerostomia, Dysphagia in Sjögren's NCT05680064	Saglik Bilimleri Universitesi	N/A
Unknown	Xerostomia in Patients With a Life-limiting Condition or Frailty NCT05506137	Maastricht University Medical Center	Phase 3
Completed	Photobiomodulation In Treatment Of Xerostomia In Type Ii Diabetic Patients NCT06703372	Hams Hamed Abdelrahman	N/A
Completed	Efficacy of a Probiotic and Microbiological Analysis on Oral Complications in Patients With HNC NCT06122636	University of Barcelona	N/A
Completed	Photobiomodulation Therapy in Patients With Head and Neck Cancer Post-Radiotherapy NCT05614843	Universidad de Granada	N/A
Completed	Beneficial Effects of Natural Products on Management of Xerostomia NCT06217614	British University In Egypt	N/A
Recruiting	Photobiomodulation Therapy Plus M-health in Head and Neck Cancer Patients: LAXER Study NCT05106608	Universidad de Granada	N/A
Completed	Clinical Evaluation of MucoPEG™ for Xerostomia NCT04986501	SunBio, Inc.	N/A
Completed	Effect of Photobiomodulation on ph and Salivary Flow NCT05413993	University of Nove de Julho	N/A
Unknown	Photobiomodulation on the Salivary Glands of Patients With Xerostomia Induced by the Use of Benzodiazepines NCT05443022	University of Nove de Julho	Phase 1 / Phase 2
Completed	Sphenopalatine Ganglion Stimulation for Ocular and Oral Dryness NCT05187533	Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA	N/A
Unknown	The Effectiveness of a Thyme and Honey Spray for Oral Toxicities NCT04880148	Cyprus University of Technology	N/A
Completed	The Effects of Traditional Chinese Medicine Mouthwash Solutions on the Oral Health of Leprosy Patients NCT05091216	Lo-Sheng Sanatorium	N/A
Completed	SaliPen Human Factors Study for OTC Labeling NCT05058430	Saliwell Ltd.	N/A
Completed	Effectiveness of Thyme Honey in Management of Xerostomia in ESRD NCT05247008	Ain Shams University	N/A
Completed	Exploratory Study on Effect of Whitening Agent With Emulsion Gel in Xerostomic Population NCT04996069	Tufts University	N/A
Completed	Effects of an External Oral Irrigation Device on Patients With Dry Mouth NCT04901507	Virginia Commonwealth University	N/A
Completed	the Effect of Mixture of Natural Products As Salivary Substitutes in Treatment Of Xerostomia NCT04252209	Cairo University	Phase 3
Unknown	Effectiveness of Photobiomodulation Protocols in Radiation-induced Oral Side Effects in H&N Cancer Patients NCT05242991	Federal University of Rio Grande do Sul	N/A
Completed	The Impact of Oral Health in HIV Patients on Antiretroviral Therapy NCT04645693	University of Pennsylvania	—
Recruiting	d-Limonene +Radiation +PlatinumBasedChemo for Xerostomia Prevention in LocallyAdvanced HNSCC NCT04392622	Stanford University	Phase 1
Completed	Blinded Dry Mouth Spray Crossover Study NCT04608773	Jonas Johnson	N/A
Unknown	Malic Acid in Treatment of Xerostomia NCT04756986	Hams Hamed Abdelrahman	N/A
Completed	Testing of a Candy in Five Different Versions for the Additional Humidification of the Oral Cavity NCT04554342	University Hospital, Basel, Switzerland	N/A
Completed	Effect of Low-level Laser Therapy on Salivary Flow, pH and Quality of Life in Irradiated Oropharyngeal Cancer NCT04738227	Ziauddin University	N/A
Completed	GUM Hydral Mouthwash vs Placebo in the Management of Hyposalivation. NCT05103124	Catholic University of the Sacred Heart	N/A
Unknown	Interest of the Sialendoscopy Associated With a Local Injection of Corticosteroids in the Treatment of Radio-i NCT04584164	Fondation Hôpital Saint-Joseph	N/A
Unknown	The Effect of Biotene® on the Symptoms of Xerostomia and Mastication and Swallowing NCT04323384	Nova Scotia Health Authority	N/A
Completed	Clinical Evaluation of Oral Rinse for Xerostomia NCT04289051	Sunstar Americas	N/A
Completed	Tolerance and Efficiency of an Intrabuccal Biological Film to Enhance Oral Dryness Sensation: The "PREDELFI" C NCT04206826	University Hospital, Brest	N/A
Completed	Influence of Two Paraffin Wax Chewing Gums of Different Consistency on the Stimulated Saliva Flow Rate NCT04661761	University Hospital, Basel, Switzerland	N/A
Unknown	Mouth Dryness and Thirst of Patients Undergone Major Abdominal Surgery NCT04657913	Ankara Medipol University	N/A
Recruiting	Interest of Auriculotherapy in the Treatment of Xerostomia NCT04222478	Hopital Foch	N/A
Completed	Evaluation of the Efficacy of 3M Dry Mouth Moisturizing Spray NCT04186806	Solventum US LLC	N/A
Completed	Salivary Gland Autotransplantation for Treatment of XRT Induced Xerostomia NCT04007081	University of Wisconsin, Madison	N/A
Unknown	Clinical Study New Gel for Xerostomia NCT04184908	Universidad de Murcia	Phase 1
Unknown	Allogeneic Mesenchymal Stem Cells for Radiation-induced Hyposalivation and Xerostomia/Dry Mouth NCT03874572	Rigshospitalet, Denmark	Phase 1
Unknown	Photobiomodulation in Salivary Production of Patients With Xerostomy NCT03632096	University of Nove de Julho	Phase 2
Unknown	Finger-prick Autologous Blood (FAB) for Use in Dry Mouth NCT03530735	Bedford Hospital NHS Trust	N/A
Completed	Periodontal Outcomes After Sanative Therapy NCT03649789	Brock University	—
Withdrawn	Use of Biotene Moisturizing Mouth Spray for Xerostomia Associated With Oral Oxybutynin Use NCT02522936	University of Southern California	Phase 4
Completed	Trial of Parotid Sparing Whole Brain Radiation NCT03595878	UNC Lineberger Comprehensive Cancer Center	N/A
Terminated	Everolimus in Restoring Salivary Gland Function in Participants With Locally Advanced Head and Neck Cancer Tre NCT03578432	University of Arizona	EARLY_Phase 1
Unknown	Effectiveness of Three Different Oral Moisturizers in Palliative Care Patients. NCT03400969	University of Bergen	N/A
Completed	"Hyaluronan" Formulation for Type 2 Diabetic Patients With Dry Mouth NCT03281486	You First Services	N/A
Unknown	Coconut Oil: Managing Radiation-Induced Xerostomia NCT03176368	Ottawa Hospital Research Institute	N/A
Completed	Comparison of Gum® HydralTM Moisturizing Gel and Biotene® Oral Gel in Dry Mouth Sensation Reduction NCT05342272	Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia	Phase 3
Unknown	Early Phase Study Comparing the Effectiveness of a Dairy Product With the Reference Treatment Aequasyal® on Dr NCT02705937	Centre Hospitalier Universitaire de Besancon	N/A
Unknown	"Hyaluronan" Formulation for Dry Mouth in Sleep Apnea Patients NCT03295019	You First Services	N/A
Terminated	Effects of Aqualief® in Patients With Xerostomia as Consequence of Radiotherapy for Head and Neck Cancer NCT03601962	Helsinn Healthcare SA	N/A
Completed	Validation of the French Version of the Xerostomia Inventory NCT03009786	CHU de Reims	—
Completed	Efficacy of Natural Enzymes Mouthwash: a Randomised Controlled Trial NCT05640362	National University of Malaysia	N/A
Completed	Topical Management of Xerostomia With Dry Mouth Products NCT03611283	Rosa María López-Pintor Muñoz	N/A
Completed	The Use of Chewing Gum for Xerostomia and Hyposalivation After Radiotherapy for Oral and Oropharyngeal Tumors NCT03302676	Odense University Hospital	N/A
Completed	Consumer Perception of an Experimental Mouthwash After a Single Use in Dry Mouth Subjects NCT03005041	GlaxoSmithKline	N/A
Completed	Effects of Photobiomodulation in Salivary Analysis of Chronic Renal Failure Patients NCT03647813	University of Nove de Julho	Phase 2
Unknown	Effect of Pilocarpine in Patients With Xerostomia NCT02982577	University of Sao Paulo	Phase 4
Completed	A Study of Patients With Dry Mouth and Sticky Saliva During Radiotherapy NCT02687087	NHS Greater Glasgow and Clyde	N/A
Completed	Potential of an Experimental Mouthwash Formulation to Reduce Dry Mouth Symptoms NCT02641912	GlaxoSmithKline	N/A
Completed	Prospective Evaluation of Patient Reported Xerostomia After Whole Brain Radiation NCT02682199	UNC Lineberger Comprehensive Cancer Center	—
Completed	Mesenchymal Stemcells for Radiation Induced Xerostomia NCT02513238	Rigshospitalet, Denmark	Phase 2
Withdrawn	Saliva, Hyperbaric Oxygen Therapy, & Gland Function: A Prospective Study NCT01532479	Loma Linda University	—
Completed	Efficacy of Traditional Persian Medicine Preparation Versus Artificial Saliva for Radiation Induced Xerostomia NCT02854358	Shiraz University of Medical Sciences	Phase 2
Completed	Acupuncture-Like Transcutaneous Electrical Nerve Stimulation in Treating Radiation-Induced Xerostomia in Patie NCT02474095	Roswell Park Cancer Institute	N/A
Completed	Effect of Childhood Radioiodine Therapy on Salivary Function NCT02375451	Boston Children's Hospital	—
Completed	Laser Therapy to Treat the Dry Mouth of Sjogren's Syndrome NCT02066896	Federal University of São Paulo	N/A
Completed	A Randomized Controlled Trial Evaluating the Effectiveness of a Salvia-based Mouthwash in Palliative Care NCT02067572	Lovisenberg Diakonale Hospital	N/A
Active Not Recruiting	Observational Study of Dental Outcomes in Head and Neck Cancer Patients NCT02057510	Wake Forest University Health Sciences	—
Completed	NeutraSal Treatment for Xerostomia in OSAS Patients Using CPAP Therapy NCT02107300	Medical University of South Carolina	N/A
Withdrawn	Development of a Milk Product Substitution for Patients Suffering From Xerostomia Caused by Medication NCT01960101	Institut National de la Santé Et de la Recherche Médicale, France	N/A
Completed	A Clinical Study to Evaluate the Efficacy of Three Dry Mouth Relief Products Versus Water NCT03494985	GlaxoSmithKline	N/A
Completed	Deterioration of Resilient Denture Liners and Patient Characteristics NCT02587676	Nihon University	—
Completed	Efficacy Study of a Ginger and Cardamom Gelatin for Xerostomy in Terminally Ill Patients NCT01915966	Fundacio Salut i Envelliment UAB	N/A
Completed	Xylitol Disk Use in Adults With Dry Mouth NCT01823445	University of Washington	N/A
Completed	Quality of Life and Sjögren Syndrome NCT03578900	Grupo de Investigação em Bioquímica e Biologia Oral	Phase 4
Completed	International Validation of the QLQ-OH17 for Oral Health NCT01724333	Oslo University Hospital	—
Completed	Efficacy of Novel Edible Gel-based Artificial Saliva in Thai Geriatric Populations With Systemic Diseases NCT02317172	Dental Innovation Foundation Under Royal Patronage	N/A
Withdrawn	Evaluation of Treatment Related Toxicity After Radiotherapy for Head and Neck Cancer NCT01621048	Universitaire Ziekenhuizen KU Leuven	—
Unknown	Treatment of Xerostomia by Herbal Preparation NCT01579877	Korea Health Industry Development Institute	N/A
Completed	Effect of a Self-adhering Material in Dental Hypersensitivity NCT02766127	Università degli Studi di Sassari	N/A
Completed	A New Oral salIvary equivAlent Compared to Two moisturizinG Mouth sprAys in Patients With xeRostomiA: NIAGARA NCT02049112	Unither Pharmaceuticals, France	Phase 4
Completed	A Trial Looking at Treating Dry Mouth After Radiotherapy for Head and Neck Cancer NCT02941276	University College, London	N/A
Completed	Effect of 0.1% Pilocarpine Mouthwash on Xerostomia NCT01627626	Jeong-seong Kwon	N/A
Terminated	Dexamethasone Irrigation of the Parotid Glands in Primary Sjögren's Syndrome Subjects NCT01316770	National Institute of Dental and Craniofacial Research (NIDCR)	Phase 2
Completed	Green Tea Lozenges for the Management of Dry Mouth NCT01647737	Augusta University	Phase 1 / Phase 2
Completed	Effects of Mucoprotective Product on Xerostomia NCT01316393	Camurus AB	Phase 4
Completed	Drug-induced Xerostomia. Evaluation of Malic Acid 1%, Salivary Mucins and Buffering Capacity NCT01652001	Universidad de Granada	Phase 2 / Phase 3
Completed	An Evaluation of the Impact of a Single Dose of P-552 on Oral Mucosal Wetness NCT01369589	Parion Sciences	Phase 1 / Phase 2
Completed	Oral Health and Oral Health-Related Quality of Life in Early Stage Breast Cancer Survivors NCT01272570	University of Michigan	—
Unknown	Treatment of Salivary Gland Hypofunction With Neuro- Electrostimulation NCT01174329	Universidad Autonoma de Nuevo Leon	Phase 2 / Phase 3
Completed	Salivary Bacteria and Oral Health Status in Children With ADHD NCT00966394	Hadassah Medical Organization	—
Terminated	Selenomethionine in Reducing Mucositis in Patients With Locally Advanced Head and Neck Cancer Who Are Receivin NCT01682031	Roswell Park Cancer Institute	Phase 2
Unknown	Xerostomia Pilot Fudan: Acupuncture for Prevention of Radiation-Induced Xerostomia NCT00862550	M.D. Anderson Cancer Center	N/A
Completed	A Safety and Efficacy Study of 552-02 in Subjects With Dry Mouth Associated With Sjogren's Syndrome NCT00852839	Parion Sciences	Phase 2
Completed	Acupuncture-Like Transcutaneous Electrical Nerve Stimulation (ALTENS) or Pilocarpine in Treating Early Dry Mou NCT00656513	Radiation Therapy Oncology Group	Phase 2 / Phase 3
Completed	Study of NGX267 Oral Capsules in Patients With Xerostomia Associated With Sjorgren's Syndrome NCT00637793	TorreyPines Therapeutics	Phase 2
Completed	Effect of Korean Red Ginseng (KRG) on Dry Mouth NCT00911768	The Korean Society of Ginseng	Phase 4
Completed	Study of the Effectiveness of Cevimeline on Oral Health in Patients With Radiation Induced Xerostomia NCT00466388	American Academy of Otolaryngology-Head and Neck Surgery Foundation	Phase 4
Unknown	Lipid Based Food Additives for Treating Patients With Dry Mouth NCT00422370	Hadassah Medical Organization	N/A
Completed	Effect of B-cell Depletion in Patients With Primary Sjögren's Syndrome NCT00426543	University of Copenhagen	Phase 2
Completed	Evaluation of an Electro-stimulator for the Treatment of Xerostomia NCT00509808	Saliwell Ltd.	Phase 4
Completed	Acupuncture for Prevention of Radiation-Induced Xerostomia NCT00430378	M.D. Anderson Cancer Center	N/A
Completed	A Comparison of Orally Pilocarpine and Artificial Saliva in Xerostomy Treatment NCT00438048	Pontificia Universidad Catolica de Chile	Phase 4
Unknown	Hypnosis for Treating Xerostomia Following Radiotherapy in Head & Neck Cancer Patients NCT00408759	Bnai Zion Medical Center	Phase 2
Terminated	Electroacupuncture in Treating Chronic Dry Mouth Caused By Radiation Therapy in Patients With Head and Neck Ca NCT00623129	Mayo Clinic	N/A
Terminated	Chemo/XRT +/- Amifostine to Assess Outcomes Related to Xerostomia, Mucositis, & Dysphagia NCT00503776	Vanderbilt-Ingram Cancer Center	Phase 2
Completed	Exploratory Study for Dry Mouth in Patients With Sjögren's Syndrome NCT00233363	Otsuka Pharmaceutical Co., Ltd.	Phase 2
Completed	Comparing Over-the-counter Dry Mouth Remedies After Radiation NCT00595933	University of Oklahoma	Phase 1
Completed	Effects of Hydroxychloroquine on Oral Complaints of Sjögren Patients NCT00873496	Ege University	—
Unknown	Parotid-Sparing Intensity-Modulated Radiation Therapy Compared With Conventional Radiation Therapy in Treating NCT00081029	Royal Marsden NHS Foundation Trust	Phase 3
Completed	Gingival Wetness and Gingival Crevicular Fluid Volume in Patients With Dry Mouth NCT00750828	Hacettepe University	—
Completed	OGT Spray in the Management of Xerostomia in the Elderly NCT00350350	Laboratoires CARILENE	—
Completed	Efficacy Study of Oxygenated Glycerol Triesters to Treat Xerostomia NCT00332618	Laboratoires CARILENE	—
Completed	Salivary Gland Surgery Before Radiation Therapy in Preventing Radiation-Caused Xerostomia in Patients With Hea NCT00068237	Radiation Therapy Oncology Group	Phase 2
Completed	Randomized Amifostine For SCCHN NCT00095927	Dana-Farber Cancer Institute	Phase 2
Completed	Study of Oral Bacteria in Patients With Dry Mouth NCT00048685	National Institute of Dental and Craniofacial Research (NIDCR)	—
Completed	Natural History of Salivary Gland Dysfunction and Sjogren's Syndrome NCT00001852	National Institute of Dental and Craniofacial Research (NIDCR)	—
Completed	Pilot Study of Thalidomide to Treat Sjogren's Syndrome NCT00001599	National Institute of Dental and Craniofacial Research (NIDCR)	Phase 2
Completed	DHEA Treatment for Sjogren's Syndrome NCT00001598	National Institute of Dental and Craniofacial Research (NIDCR)	Phase 2
Completed	Structure and Functional Status of Parotid Glands Exposed to Therapeutic Irradiation NCT00001523	National Institute of Dental and Craniofacial Research (NIDCR)	—
Unknown	Can Cytokines Predict the Severity of Acute Mucositis and the Need for Gastrostomy Tubes (PEG)? NCT00431925	Hadassah Medical Organization	—