NCT06476223

Artificial Saliva Containing Cumin and Ginger Extract in Hemodialysis Patients With Xerostomia

Efficacy and Safety of Artificial Saliva Containing Cumin and Ginger Extract in Hemodialysis

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 26 (estimated)
• Sponsor: Chulalongkorn University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Hemodialysis patients with xerostomia are divided into 2 groups which are group A (start with artificial saliva containing cumin and ginger extract for 2 weeks, free periods 2 weeks, then placebo for 2 weeks) and group B (start with placebo for 2 weeks, free periods 2 weeks, then artificial saliva containing cumin and ginger extract for 2 weeks). Amount of saliva (g/min), xerostomia's questionnaire, Increase of saliva score, World Health Organization Oral Mucositis Grading Scale, acid and base of saliva, quality of life's questionnaire will measure before, after using the sample for 7 and 14 days.

Conditions

• Xerostomia

Interventions

Type	Name	Description
DRUG	Artificial saliva containing cumin and ginger extract	The sample will be sprayed 2 puff/time, 3 times/day, for 14 days.
DRUG	Placebo	The sample will be sprayed 2 puff/time, 3 times/day, for 14 days.

Timeline

• Start date: 2024-07-01
• Primary completion: 2024-12-30
• Completion: 2025-01-31
• First posted: 2024-06-26
• Last updated: 2024-07-01