NCT05872464

Artificial Saliva Containing Cumin and Ginger Extract in Head and Neck Cancer Patients With Xerostomia

Efficacy and Safety of Artificial Saliva Containing Cumin and Ginger Extract in Head and Neck Cancer Patients With Xerostomia

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 52 (estimated)
• Sponsor: Chulalongkorn University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The objectives of this study are to evaluate efficacy and safety of artificial saliva containing cumin and ginger extract in head and neck cancer patients with xerostomia.

Detailed description

There are 52 patients in this study. They are divided into 2 groups which are artificial saliva containing cumin and ginger extract group (test group) 26 patients and placebo group 26 patients. The patients spray the sample into the mouth 3 times/day for 14 day. Amount of saliva, pH of saliva, xerostomia questionnaires, WHO Oral Mucositis Grading Scale, quality of life, adverse events, and satisfaction were assessed.

Conditions

• Xerostomia

Interventions

Type	Name	Description
OTHER	Artificial saliva containing cumin and ginger extract	Artificial saliva containing cumin and ginger extract in spray bottle
OTHER	Placebo	Placebo containing composition close to the test group without cumin and ginger extract in spray bottle

Timeline

• Start date: 2024-07-01
• Primary completion: 2025-05-30
• Completion: 2025-06-30
• First posted: 2023-05-24
• Last updated: 2024-06-24