NCT02107300

NeutraSal Treatment for Xerostomia in OSAS Patients Using CPAP Therapy

NeutraSal in the Management of Xerostomia in Obstructive Sleep Apnea Syndrome (OSAS) Patients Utilizing Continuous Positive Airway Pressure (CPAP) Therapy

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 32 (actual)
• Sponsor: Medical University of South Carolina · Academic / Other
• Sex: All
• Age: 18 Years – 84 Years
• Healthy volunteers: Not accepted

Summary

To assess whether the daily use of NeutraSal will prevent or reduce dry mouth in patients undergoing CPAP therapy for OSAS and improve CPAP compliance

Detailed description

Subjects diagnosed with Obstructive Sleep Apnea Syndrome (OSAS) who have started CPAP treatment and have complained of dry mouth or developed worsening of a pre-existing dry mouth as an effect of CPAP treatment will test the effectiveness of NeutraSal mouthwash in preventing or reducing his/her dry mouth perceptions and improving their compliance with CPAP.

Conditions

• Xerostomia

Interventions

Type	Name	Description
DRUG	NeutraSal	NeutraSal is a powder that when dissolved in water creates a supersaturated calcium phosphate rinse.
DRUG	Placebo Comparator	Placebo is a powder consisting of sodium chloride only; chosen to mimic NeutraSal

Timeline

• Start date: 2013-11-01
• Primary completion: 2015-04-10
• Completion: 2017-07-03
• First posted: 2014-04-08
• Last updated: 2018-12-11
• Results posted: 2018-12-11

Locations

1 site across 1 country: United States