| Not Yet Recruiting | Physiological Effects of Controlled vs. Assisted Ventilation During Moderate-to-severe ARDS (PEARL Study) NCT07315815 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Recruiting | Dynamic Compliance-Guided Ventilation in Lumbar Surgery NCT07349719 | Ankara City Hospital Bilkent | N/A |
| Recruiting | Inspiratory Effort-Targeted Pressure Support Ventilation (IT-PSV) Trial NCT06526598 | Capital Medical University | N/A |
| Recruiting | Electrical Impedance Tomography-Based Prognostic Model for ARDS NCT06967207 | XiaoJing Zou,MD | — |
| Not Yet Recruiting | Ventilation of the Extremely Premature Infants Optimized by Dead Space Washout NCT06334523 | Centre Hospitalier Intercommunal Creteil | N/A |
| Recruiting | EIT-Guided Ventilator Settings in AHRF NCT06936618 | Mahidol University | N/A |
| Recruiting | Open Lung Protective Extubation Following General Anesthesia NCT06296173 | Centre hospitalier de l'Université de Montréal (CHUM) | N/A |
| Recruiting | Non-invasive Phrenic Nerve Stimulation in ARDS Patient NCT06572280 | Southeast University, China | N/A |
| Enrolling By Invitation | Evaluation of Respiratory Mechanics in Supine and PARK-bench Positions (SPARK) NCT06448988 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Not Yet Recruiting | Effect of Vitamin C on Postoperative Pulmonary Complications After Intracranial Tumor Surgery NCT06421688 | Qianfoshan Hospital | Phase 2 |
| Completed | Novel Oxygenation Indices in Robot-Assisted Laparoscopic Surgeries NCT06430606 | Başakşehir Çam & Sakura City Hospital | — |
| Enrolling By Invitation | Optimizing the Assessment of Mechanical Ventilation by Integrating Advanced Monitoring Techniques [AVIM] NCT06236685 | Czech Technical University in Prague | N/A |
| Active Not Recruiting | Phrenic Identification in the ICU NCT05875883 | Unity Health Toronto | — |
| Completed | Comparing Mechanical Power in Different Inspiratory Times NCT06413472 | Başakşehir Çam & Sakura City Hospital | — |
| Unknown | Efficacy and Safety of Automated Closed-loop Ventilator vs Conventional Open-loop Ventilator in the Emergency NCT06157073 | University of Malaya | N/A |
| Completed | Optimal Positive End-Expiratory Pressure in Robotic-Assisted Thoracic Surgery NCT06026670 | Hospital Clinic of Barcelona | — |
| Recruiting | Mechanism Study of Ventilator-Induced Lung Injury in Elderly People. NCT06367946 | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | — |
| Unknown | The Effect of Two Different Intra-abdominal Pressure Applications on "Mechanical Power" in Laparoscopic Cholec NCT05859906 | Ayse Ulgey | — |
| Active Not Recruiting | CT for Personalized Mechanical Ventilation NCT05977153 | Columbia University | N/A |
| Unknown | Effect of End-inspiratory Airway Pressure Measurements on the Risk of VILI in Ventilated Patients NCT05991258 | University of Padova | — |
| Unknown | Evaluation of Regional Ventilation Distribution Using Electrical Impedance Tomography During Weaning From Mech NCT05726513 | Università degli Studi di Ferrara | N/A |
| Recruiting | Electrical Activity of the Diaphragm and Respiratory Mechanics During NAVA NCT05689476 | University of Padova | N/A |
| Unknown | QT Distance and P Dispersion in ECG in Patients Having Bronchoscopy in the ICU NCT05434624 | Abant Izzet Baysal University | N/A |
| Recruiting | "Lung Barometric Measurements in Normal And in Respiratory Distressed Lungs" NCT04484727 | Göteborg University | — |
| Completed | Assessing Ventilator Safety in Patients on Pressure-Support Ventilation NCT05125952 | Duke University | N/A |
| Withdrawn | Paradoxical Response to Chest Wall Loading in Mechanically Ventilated Patients NCT06093958 | HealthPartners Institute | N/A |
| Completed | Ventilation and Perfusion in the Respiratory System NCT05081895 | University of California, San Diego | — |
| Completed | Optimization of PEEP During Laparoscopic Surgery NCT05222893 | Karaganda Medical University | N/A |
| Terminated | Providing Optimal PEEP During Mechanical Ventilation for Obese Patients Using Esophageal Balloon NCT03951064 | University of North Carolina, Chapel Hill | N/A |
| Completed | How To Prevent Ventilator-Related Lung Damage in Intraoperative Mechanical Ventilation? Pcv or Vcv ? NCT05814081 | Başakşehir Çam & Sakura City Hospital | — |
| Unknown | Bilateral Bi-level Erector Spine Plane Block as a Component of General Anesthesia in Surgical Correction of Sp NCT04697498 | Lviv National Medical University | N/A |
| Completed | Respiratory Mechanics During One-lung Ventilation NCT04519606 | E-DA Hospital | — |
| Recruiting | Clinical Decision Support Tool in PARDS Pilot Study NCT04068012 | Children's Hospital Los Angeles | N/A |
| Recruiting | Inspiratory Work of Breathing Before and After Extubation NCT07017608 | University Health Network, Toronto | — |
| Unknown | Effects of Large Tidal Volumes Despite Minimal Inspiratory Support in Spontaneously Ventilated Intubated Resus NCT05056961 | University Hospital, Clermont-Ferrand | N/A |
| Completed | Ventilator-induced Lung Injury Vortex in Patients With SARS-CoV-2 NCT04174313 | Hospital El Cruce | — |
| Completed | Impact of Decreasing Respiratory Rate on Lung Injury Biomarkers in ARDS Patients NCT04641897 | Pontificia Universidad Catolica de Chile | N/A |
| Completed | Impact of the Depth of Neuromuscular Blockade on Respiratory Mechanics in Moderate to Severe ARDS Patients NCT05697666 | Centre Hospitalier de Saint-Brieuc | — |
| Completed | Comparison of Mechanical Power Calculations of Volume Control and Pressure Control Modes NCT05494554 | Bakirkoy Dr. Sadi Konuk Research and Training Hospital | — |
| Unknown | Extrapulmonary Lung Protection Strategy for Patients With Mechanical Ventilation NCT03947476 | Shanghai Zhongshan Hospital | — |
| Completed | A Central and Eastern European Survey On PEEP Titration and Alveolar Recruitment Manoeuvres During Surgery NCT04030078 | Péterfy Sándor Hospital | — |
| Completed | Ventilator Settings on Patients With Acute Brain Injury NCT03278769 | University Hospital of North Norway | N/A |
| Unknown | New Automated System for Continuous Real-time Monitoring of Transpulmonary Pressure NCT03945409 | University of Milan | — |
| Completed | A New Ultrasonographic Tool to Assess Pulmonary Strain in Patients Under One-lung Ventilation. NCT03817918 | Centre hospitalier de l'Université de Montréal (CHUM) | N/A |
| Unknown | Transpulmonary Pressure Under Stressing Conditions NCT03746236 | Regina Elena Cancer Institute | — |
| Unknown | Driving Pressure Variation: NAVA vs PSV NCT03719365 | Azienda Ospedaliero Universitaria Maggiore della Carita | N/A |
| Completed | Lung Protection Strategy in Open Heart Surgery: Which Tidal Volume is Better 8ml/kg or 6ml/kg NCT03651817 | Kocaeli University | N/A |
| Active Not Recruiting | Long Term Follow up of Children Enrolled in the REDvent Study NCT03709199 | Children's Hospital Los Angeles | — |
| Withdrawn | Effect of PEEP on Lung Recruitment and Homogeneity Over Time in Moderate to Severe ARDS NCT03140579 | Guy's and St Thomas' NHS Foundation Trust | — |
| Terminated | Enhanced Lung Protective Ventilation With ECCO2R During ARDS NCT03525691 | Hôpital Européen Marseille | N/A |
| Completed | Percutaneous Temporary Placement of a Transvenous Phrenic Nerve Stimulator for Diaphragm Pacing Using Jugular NCT03659552 | Lungpacer Medical Inc. | N/A |
| Completed | Transpulmonary Driving Pressure and Intra-abdominal Pressure Relationship During Laparoscopic Surgery NCT03435913 | Hospital Universitario La Fe | N/A |
| Recruiting | A New Ultrasonographic Tool to Assess Pulmonary Strain in the ICU NCT03405779 | Centre hospitalier de l'Université de Montréal (CHUM) | — |
| Unknown | Physiological Response in Lung Transplant Recipients Undergoing Neurally Adjusted Ventilatory Assist NCT03367221 | Policlinico Hospital | N/A |
| Completed | Assesment of the Endotracheal Tube Cuff Pressure Values in ICU Pateints Before and After Training Seminar NCT03401463 | Jagiellonian University | N/A |
| Unknown | Assisted or Controlled Ventilation in Ards (Ascovent) NCT03245684 | University of Roma La Sapienza | N/A |
| Completed | Mid and Standard Frequency Ventilation in Infants With Respiratory Distress Syndrome NCT03231735 | University of Alabama at Birmingham | Phase 2 / Phase 3 |
| Completed | A New Ultrasonographic Tool to Assess Regional Pulmonary Strain NCT03092557 | Centre hospitalier de l'Université de Montréal (CHUM) | N/A |
| Completed | Pressure Support Ventilation During Laparoscopic and Abdominal Robotic Surgery. NCT04815733 | Moscow Clinical Scientific Center | N/A |
| Completed | Ultra Protective Ventilation During Venoarterial Extracorporeal Membrane Oxygenation (UPV-ECMO) NCT03041428 | Fundación para la Investigación Biosanitaria del Principado de Asturias | N/A |
| Withdrawn | Intraop Ventilation Management and Postop Pulmonary Complications in High Risk Patients for OSA NCT03135691 | Ohio State University | — |
| Withdrawn | Randomized Study to Investigate the Safety and Performance of Diaphragm Stimulation Coupled With Mechanical Ve NCT04457427 | Synapse Biomedical | N/A |
| Completed | Comparison of Different Ventilation Mode During One-lung Ventilation NCT03061617 | Shanghai Zhongshan Hospital | N/A |
| Completed | Asynchrony During Mechanical Ventilation in Patients With Acute Respiratory Distress Syndrome NCT02732041 | Centro de Educación Medica e Investigaciones Clínicas Norberto Quirno | — |
| Completed | Inflammatory Local Response During OLV: Protective vs Conventional Ventilation Strategy NCT03056885 | University of Roma La Sapienza | N/A |
| Completed | Intraoperative Lung-Protective Ventilation in Neurosurgery NCT02386683 | Capital Medical University | N/A |
| Completed | Percutaneous Temporary Placement of a Phrenic Nerve Stimulator for Diaphragm Pacing, a First in Human Trial NCT02670460 | Lungpacer Medical Inc. | N/A |
| Completed | Protective Mechanical Ventilation and Risk of Postoperative Complications in Abdominal Surgery NCT03165760 | Mongi Slim Hospital | N/A |
| Unknown | Esophageal Pressure-Guided Optimal PEEP/mPaw in CMV and HFOV: The EPOCH Study NCT02342756 | University of Toronto | N/A |
| Unknown | High Frequency Oscillatory Ventilation Combined With Intermittent Sigh Breaths: Effects on Blood Oxygenation a NCT01959009 | Rigshospitalet, Denmark | N/A |
| Completed | APRV/BIPAP With Spontaneous Breathing on Lung Protection NCT02071277 | Unity Health Toronto | N/A |
| Completed | Hemodynamic and Respiratory Variations During Laparoscopic Surgery With and Without Deep Neuromuscular Blockad NCT02025075 | Massachusetts General Hospital | N/A |
| Completed | High Frequency Oscillatory Ventilation Combined With Intermittent Sigh Breaths: Effects on Lung Volume Monitor NCT01962818 | Rigshospitalet, Denmark | N/A |
| Completed | Local Assessment of Ventilatory Management During General Anesthesia for Surgery NCT01601223 | European Society of Anaesthesiology | — |
| Completed | Ventilatory Parameters and Inflammatory Responses of Neonates Ventilated by Different Modes of Ventilation NCT01514331 | Gazi University | N/A |
| Completed | Intensive Alveolar Recruitment Protocol After Cardiac Surgery NCT01502332 | University of Sao Paulo | N/A |