NCT04815733

Pressure Support Ventilation During Laparoscopic and Abdominal Robotic Surgery.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 106 (actual)
• Sponsor: Moscow Clinical Scientific Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This study is a single-center, blind, prospective, randomized, controlled trial of pressure support ventilation (PSVpro) versus pressure control ventilation - volume guaranteed (PCV - VG) during laparoscopic and robotic abdominal surgery.

Detailed description

The objective of the study to evaluate the possibility and feasibility of using PSVpro during anesthesia during long-term laparoscopic and robot-assisted abdominal operations at different levels of neuromuscular block. Intervention: We plan to include 100 patients who will undergo elective long (more 2 hours) laparoscopic or abdominal robotic surgery. All patients will be randomly assigned in two groups in ratio 1:1. 1 group- deep neuromuscular block and mandatory ventilation; 2 group- partial neuromuscular block and pressure support ventilation. Expected Results. PSV may reduce the systemic inflammatory response compared to the mandatory ventilation during laparoscopic and abdominal robotic surgery.

Conditions

• Ventilator-Induced Lung Injury

Interventions

Type	Name	Description
PROCEDURE	Mandatory ventilation	Use PCV-VG
PROCEDURE	pressure support ventilation	Use PSVpro

Timeline

• Start date: 2017-06-01
• Primary completion: 2023-03-31
• Completion: 2023-03-31
• First posted: 2021-03-25
• Last updated: 2023-04-26

Locations

1 site across 1 country: Russia